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Research and Teaching Associate
SB
SB-SCGC
SCGC-ENS

Research and Teaching Associate
SB
SB-SCGC
SCGC-GE
Research and Teaching Associate
ISIC - Administration
Scientific Staff Member
School Council SB
Christophe Roussel
Dr es Chimie-Physique

office(s): CHC0426
phone(s): [+41 21 69] 37675
Organic Chemistry
Cycloaddition of some arylnitriloxides with 3-methylenephtalide: electrocatalytic openning of the adduct
C. Roussel, K. Ciamala, P. Audebert, J. Vebrel, New Journal of Chemistry, 23: 989-992, 1999.

Contribution of microwaves in organic synthesis: statement of a methodology for the microwave-induced preparation of benzofuran-2(3H)-one and its comparison with classical heating
P. Concalo, C. Roussel, J-M. Melot, J. Vebrel, Journal of the Chemical Society Perking Trans. 2, 2111-2115, 1999.

Revisiting the addition of nitriloxides on protoanemonine. A new access to (2E)-3-(3'-arylisoxazol-5'-yl)propenoic acids
C. Roussel, R. Fihi, K. Ciamala, P. Audebert, J. Vebrel, New Journal of Chemistry, 24: 471-476, 2000.

The [3+2] cycloaddition of diphenyldiazomethane and ethyl diazoacetate with itaconic anhydride. A new access to spiranic cyclopropane derivatives
C. Roussel, K. Ciamala, J-M. Melot, J. Vebrel, C. Riche, Journal of Chemical research (s), 9: 449-451, 2002.

Spiroheterocycles from reaction of nitrones with methylene-gamma-butyrolactones and some of their rearrangements
C. Roussel, R. Fihi, K. Ciamala, J. Vebrel, T. Zair, C. Riche, Organic and Biomolecular Chemistry, 1: 2689-2698, 2003.

Mechanistic aspect of on-line electrochemical tagging of free L-cysteine residues during electrospray ionisation for mass spectrometry in protein analysis
C. Roussel, T. C. Rohner, H. Jensen, H. H. Girault, ChemPhysChem, 4: 200-206, 2003.

On-line cysteine modification for protein analysis: new probes for electrochemical tagging nanospray mass spectrometry
C. Roussel, L. Dayon, H. Jensen, and H. H. Girault, Journal of Electroanalytical Chemistry, 570: 187-199, 2004.

2,3-diphenyl-2,3-dihydrospiro[1,3-oxazole-5(4H),1'(3'H)-2-benzofuran]-3'-one
J.-C. Daran, R. Fihi, C. Roussel, N. Laghrib, M. Azrour, K. Ciamala, J. Vebrel, Acta Crystallographica E, 62: o329-o331, 2006.

Reaction of 3-methylenedihydro-(3H)-furan-2-one with diazoalkanes. Syntheses and crystal structures of spiranic cyclopropyl compounds
C. Roussel, K. Ciamala, J. Vebrel, M. Knorr, M. M. Kubicki, Heterocycles, 71: 1517-1528, 2007.

Electrochemical generation of Cu(I) complexes in aqueous solutions studied by on-line mass spectrometry
M. Prudent, C. Roussel, H. H. Girault, Electrochemistry Communications, 9: 2067-2074, 2007.

Protoporphyrin IX sensitized titanium oxide gel electrode
S. X. Tan, B. Su, C. Roussel, H. H. Girault, Inorganica Chimica Acta, 361: 746-760, 2008.

Reactivity of arynitriloxides and C-aroyl-N-phenylnitrones with 3-methylenedihydro-(3H)-furan-2-one and itaconic anhydride
C. Roussel, K. Ciamala, J. Vebrel , C. Riche, Heterocycles, 78: 1977-1991, 2009.
Analytical and Physical Chemistry
Microfluidic systems in proteomics
N. Lion, T. C. Rohner, L. Dayon, I. L. Arnaud, E. Damoc, N. Youhnovski, Z.-Y. Wu, C. Roussel, J. Josserand, H. Jensen, J. S. Rossier, M. Przybylski, H. H. Girault, Electrophoresis, 24: 3533-3562, 2003.

Generation of mass tags by the inherent electrochemistry of electrospray for protein mass spectrometry
C. Roussel, L. Dayon, N. Lion, T. C. Rohner, J. Josserand, J. S. Rossier, H. Jensen, H. H. Girault, Journal of the American Society for Mass Spectrometry, 15: 1767-1779, 2004.

On-line electrochemical tagging of free cysteine during nanospray ionisation for mass spectrometry analysis
C. Roussel, L. Dayon, T. C. Rohner, N. Lion, H. H. Girault, Biophotonics New Frontier: From Genome to Proteome, Proceedings of Spie, 5461: 30-37, 2004.

Polyelectrolyte modified short microchannel for cation separation
X. Bai, C. Roussel, H. Jensen, and H. H. Girault, Electrophoresis, 25: 931-935, 2004.

On-line electrochemical tagging of free cysteines in peptides during nanospray ionisation mass spectrometry: An Overview
L. Dayon, C. Roussel, H. H. Girault, Chimia, 58: 204-207, 2004.

On-Line counting of cysteine residues in peptides during electrospray ionization by electrogenerated tags and their application to protein identification
L. Dayon, C. Roussel, M. Prudent, N. Lion, H. H. Girault. Electrophoresis, 26: 238-247, 2005.

Antioxidant sensors based on DNA-modified electrodes
J. F. Liu, C. Roussel, G. Lagger, P. Tacchini, and H. H. Girault, Analytical Chemistry, 77: 7687-7694, 2005.

Size-selective separation of Gold nanoparticles using isoelectric focusing electrophoresis (IEF)
I. L. Arnaud, J.-P. Abid, C. Roussel, H. H. Girault, Chemical Communications, 787-788, 2005.

Salt removal during off-gel electrophoresis of protein samples
I. L. Arnaud, J. Josserand, H. Jensen, N. Lion, C. Roussel, H. H. Girault, Electrophoresis, 26: 1650-1658, 2005.

Probing cysteine reactivity in proteins by Mass Spectrometric EC-tagging
L. Dayon, C. Roussel, and H. H. Girault, Journal of Proteome Research, 5: 793-800, 2006.

Immobilized pH gradient gel cell to study the pH dependence of drug lipophilicity
H.-T. Lam, C. M. Pereira, C. Roussel, P.-A. Carrupt, H. H. Girault, Analytical Chemistry, 78: 1503-1508, 2006.

Electrochemical generation of Cu(I) complexes in aqueous solutions studied by on-line mass spectrometry
M. Prudent, C. Roussel, H. H. Girault, Electrochemistry Communications, 9: 2067-2074, 2007.

Specific on-plate enrichment of phosphorylated peptides for direct MALDI-TOF MS analysis
L. Qiao, C. Roussel, J. J. Wan, P. Y. Yang, H. H. Girault, B. H. Liu, Journal of Proteome Research, 6: 4763-4769, 2007.

MALDI in-source photo-oxidation reactions for on-line peptide tagging
L. Qiao, C. Roussel, J. J. Wan, J. L. Kong, P. Y. Yang, H. H. Girault, B. H. Liu, Angewandte Chemie, International Edition, 47: 2646-2648, 2008.

About the electrospray ionization source in Mass Spectrometry: electrochemistry and on-chip reactions
M. Prudent, M. A. Méndez, C. Roussel, B. Su, N. Lion, J. S. Rossier, H. H. Girault, Chimia, 63: 283-287, 2009.

Photocatalytic discoloration of aqueous malachite green solutions by UV-illuminated TiO2 nano-particles under air and nitrogen atmospheres: effects of counter-ions and pH
J.A. Rengifo-Herrera, L.R. Pizzo, M.N. Blanco, C. Roussel, C. Pulgarin, Photochemical and photobiological sciences, 10: 29-34, 2011.
Patents
Chemical wall-plug product comprises separate components which, when mixed, undergo simultaneous expansion and polymerization-crosslinking reactions to form an expanded 3-dimensional thermoset structure
J. Vebrel, P. Goncalo, C. Roussel, J. Vuillermoz, PCT/FR2000/01132, WO2000/66673-A, 2000.

Ionisation device
L. Qiao, P.Y. Yang, B. Liu, N. Lion, C. Roussel, H.H. Girault, PCT/EP2008/000140, WO2008/083966, 2008.


Solid-phase extraction and ionisation device
B. Liu, L. Qiao, N. Lion, J.J. Wan, M. Prudent, C. Roussel, P.Y. Yang, H.H. Girault, PCT/EP2008/5347, WO2009/003673, 2009.


Skills
Analytical Chemistry
Analytical Electrochemistry
Organic Synthesis
Organic Electrosynthesis
Sol-Gel processes
Teaching
Chemistry and Chemical Engineering


©2004-2012 Christophe Roussel - EPFL, 1015 Lausanne - last updated : 2010-12-31 11:25:09
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