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Graham Knott
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MISSION
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Graham Knott is a researcher in the field of neuroscience and head of the Bio EM facility at the EPFL. He has many years experience in electron microscopy particularly in the field of neuronal structure. As head of the BioEM facility Graham lectures on various aspects of EM for life science and provides a wide range of EM techniques to life scientists at the EPFL, and the wider community.
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MORE RECENT PUBLICATIONS
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Holtmaat A, De Paola V, Wilbrecht L, Knott GW. Imaging of experience-dependent structural plasticity in the mouse neocortex in vivo. Behav Brain Res. 2008 Sep 1;192(1):20-5.
Knott G, Marchman H, Wall D, Lich B. Serial section scanning electron microscopy of adult brain tissue using focused ion beam milling. J Neurosci. 2008 Mar 19;28(12):2959-64.
Knott G, Holtmaat A. Dendritic spine plasticity-Current understanding from in vivo studies.
Brain Res Rev. 2008 Aug;58(2):282-9.
Chattopadhyaya B, Di Cristo G, Wu CZ, Knott G, Kuhlman S, Fu Y, Palmiter RD, Huang ZJ. GAD67-Mediated GABA Synthesis and Signaling Regulate Inhibitory Synaptic Innervation in the Visual Cortex. Neuron. (2007) 54:889-903.
Genoud C., Quairiaux C., Steiner P., Hirling H., Welker E., & Knott, G.W. (2006) Plasticity of astrocytic coverage and glutamate transporter expression in adult mouse cortex. PLoS Biol 4(11): e343.
Knott, G.W., Holtmaat, A., Wilbrecht, L., Welker, E. & Svoboda, K. Spine growth precedes synapse formation in the adult neocortex in vivo. Nat Neurosci 9, 1117-24 (2006).
Holtmaat, A., Wilbrecht, L., Knott, G.W., Welker, E. & Svoboda, K. Experience-dependent and cell-type-specific spine growth in the neocortex. Nature 441, 979-83 (2006).
Kitchener, P.D., Hutton, E.J. & Knott, G.W. Primary sensory afferent innervation of the developing superficial dorsal horn in the South American opossum Monodelphis domestica. J Comp Neurol 495, 37-52 (2006).
Holtmaat A.J., Trachtenberg J.T., Wilbrecht L., Shepherd G.M., Zhang X., Knott G.W., Svoboda K. (2005) Transient and persistent dendritic spines in the neocortex in vivo. Neuron 45:279-291.
Chattopadhyaya B., Di Cristo G., Higashiyama H., Knott G.W., Kuhlman S.J., Welker E., Huang Z.J. (2004) Experience and activity-dependent maturation of perisomatic GABAergic innervation in primary visual cortex during a postnatal critical period. J Neurosci 24:9598-9611.
Cristo G.D., Wu C., Chattopadhyaya B., Ango F., Knott G., Welker E., Svoboda K., Huang Z.J. (2004) Subcellular domain-restricted GABAergic innervation in primary visual cortex in the absence of sensory and thalamic inputs. Nat Neurosci 7:1184-1186.
Genoud C., Knott G.W., Sakata K., Lu B., Welker E. (2004) Altered synapse formation in the adult somatosensory cortex of brain-derived neurotrophic factor heterozygote mice. J Neurosci 24:2394-2400. Impact factor 7.5
Zito K., Knott G., Shepherd G.M., Shenolikar S., Svoboda K. (2004) Induction of spine growth and synapse formation by regulation of the spine actin cytoskeleton. Neuron 44:321-334.Impact factor 14.3
Voutsinos-Porche B., Knott, G., Tanaka K., Quairiaux C., Welker E., Bonvento G. (2003) Glial glutamate transporters and maturation of the mouse somatosensory cortex. Cereb Cortex. 10, 1110-21. Impact factor 6.19
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