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Student ETU EDOC EDIC Doctoral Assistant IC ISC LANOS

Marc Hafner Doctoral Program in Computer & Communication Sciences birth date: 05.11.1982 nationality: Swiss web site: http://picasaweb.google.com/hafner.marc office(s): BC212 phone(s): [+41 21 69] 31293 MISSION The goal of my PhD is to quantify robustness of biochemical networks. I am currently developing a method to quantify the robustness of the cyanobacterial circadian cycle. My other topics of interest are the evolution of feedback loops in biochemical systems and the network of circadian oscillators. BIOGRAPHY Master of physics 2007 at EPFL, I wrote my Master Thesis on the aggregation of the polyglutamine chains with Prof. Paolo de Los Rios (LBS - SB - EPFL). Since May 2007, I have been working as a PhD student in the laboratory of nonlinear systems under the supervision of Prof. M. Hasler and Dr. H. Koeppl. Prof. A. Wagner (University of Zurich) is the co-advisor for my thesis. MAIN PUBLICATIONS M. Hafner, P. Sacre, H. Koeppl, and R. Sepulchre. Multiple feedback loops in circadian cycles: robustness and entrainment as selection criteria. In Proceedings of the 7th International Workshop on Computational Systems Biology, 2010. [ Details ] M. Hafner, H. Koeppl, M. Hasler, and A. Wagner. ‘glocal’ Robustness Analysis and Model Discrimination for Circadian Oscillators. PLoS Computational Biology, 5(10):e1000534, 2009. [ Details | Full Text ] H. Koeppl, M. Hafner, and R. Steuer. Semi-quantitative stability analysis constrains saturation levels in metabolic networks. In International Workshop on Computational Systems Biology, 2009. [ Details | Full Text | Link ] H. Koeppl, M. Hafner, and V. Danos. Rule-based modeling for protein-protein interaction networks - the cyanobacterial circadian clock as a case study. In International Workshop on Computational Systems Biology, 2009. [ Details | Full Text | Link ] M. Hafner, H. Koeppl, and A. Wagner. Robustness and evolution in oscillatory systems with feedback loops. In Third International Conference on Foundations of Systems Biology in Engineering, 2009. [ Details | Full Text | Link ]

Skills Programming in C/C++, MATLAB Biological modeling using MATLAB, Kappa formalism