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Mayumi Mochizuki
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BIOGRAPHY
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< EDUCATION >
2005 Spt.: Ph.D. in Bioengineering, Hokkaido University, Japan
2003 Mar.: M.S. in Bioengineering, Hokkaido University, Japan
2001 Mar.: B.S. in Polymer Science, Faculty of Science, Hokkaido University, Japan
< PROFESSIONAL EXPERIENCE >
2006 Apr. -present: Scientific Collaborator, Ecole Polytechnique Fédérale de Lausanne, Switzerland
2005 Oct. -2006 Mar.: Scientific Researcher, Hokkaido University, Japan (Dr. Motoyoshi Nomizu)
2005 Oct.- Dec.:
2005 Apr.- Jun.:
2002 Sep.- Oct.:
Guest Researcher, National Institute of Dental and Craniofacial Research, National Institutes of Health, United States (Chief. Dr. Hynda K Kleinman)
< AWARDS AND FELLOWSHIPS >
2006 Apr. - 2007 Mar.: An international postdoctoral fellowship under the exchange program between the Swiss National Science Foundation (SNSF) and the Japan Society of the Promotion of Science (JSPS)
2003 Apr. - 2006 Mar.: JSPS Research Fellow
2004: Travel Award, Gordon Research Conference (Basement Membrane)
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MAIN PUBLICATIONS
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A novel cell-adhesive scaffold material for delivering keratinocytes reduces granulation tissue in dermal wounds, Masuda, R., Mochizuki, M., Hozumi, K., Takeda, A., Uchinuma, E., Yamashina, S., Nomizu, M., and Kadoya, Y, Wound Repair Regen., 17: 127-135,2009
Controlling integrin specificity and stem cell differentiation in 2D and 3D environments through regulation of fibronectin domain stability, Martino, M.M., Mochizuki, M., Rothenfluh, D.A., Rempel, S.A., Hubbell, J.A., and Barker, T.H., Biomaterials, in press
Angiogenic activity of syndecan-binding laminin peptide AG73 (RKRLQVQLSIRT), Mochizuki, M., Philp, D., Hozumi, K., Suzuki, N., Yamada, Y., Kleinman, H. K., and Nomizu, Arch. Biochem. Biophys., 459: 249-255, 2007
Cyclic peptide analysis of the biologically active loop region in the laminin alpha3 chain LG4 module demonstrates the importance of peptide conformation on biological activity, Kato-Takagaki, K., Suzuki, N., Yokoyama, F., Takaki, S., Umezawa, K., Higo, J., Mochizuki, M., Kikkawa, Y., Oishi S., Utani A., and Nomizu, M, Biochemistry, 46: 1952-1960, 2007
Integrin-dependent cell behavior on ECM peptide-conjugated chitosan membranes, Mochizuki, M., Yamagata, N., Philp, D., Hozumi, K., Watanabe, T., Kikkawa, Y., Kadoya, Y., Kleinman, H. K., and Nomizu M, Biopolymers, 88: 112-130, 2007
Laminin peptide-conjugated chitosan membrane: Application for keratinocyte delivery in wounded skin, Ikemoto, S., Mochizuki, M., Yamada, M., Takeda, A., Uchinuma, E., Yamashina, S., Nomizu, M., and Kadoya, Y, J Biomed Mater Res A., 79: 716-722, 2006
Laminin alpha5 chain metastasis-and angiogenesis-inhibiting peptide blocks fibroblast growth factor 2 activity by binding to the heparan sulfate chains of CD44, Hibino, S., Shibuya, M., Hoffman, M. P., Engbring, J. A., Hossain, R., Mochizuki, M., Kudoh, S., Nomizu, M., and Kleinman, H. K, Cancer Res., 65: 10494-10501, 2005
Laminin active peptides as a powerful tool for biomedical materials, Mochizuki, M., Kadoya, Y., and Nomizu, M, Tanpakushitsu Kakusan Koso, 50: 374-382, 2005
Identification of an active site on the laminin alpha5 chain globular domain that binds to CD44 and inhibits malignancy, Hibino, S., Shibuya, M., Engbring, J. A., Mochizuki, M., Nomizu, M., and Kleinman, H. K, Cancer Res., 64: 4810-4816, 2004
Multifunctional peptide fibrils for biomedical materials, Kasai, S., Ohga, Y., Mochizuki, M., Nishi, N., Kadoya, Y., and Nomizu, M, Biopolymers, 76: 27-33, 2004
Biological activities of homologous loop regions in the laminin alpha chain G domains, Suzuki, N., Nakatsuka, H., Mochizuki, M., Nishi, N., Kadoya, Y., Utani, A., Oishi, S., Fujii, N., Kleinman, H. K., and Nomizu, M, J. Biol. Chem., 278: 45697-45705, 2003
Role for laminin-?5 chain LG4 module in epithelial branching morphogenesis, Kadoya, Y., Mochizuki, M., Nomizu, M., Sorokin, L., and Yamashina, S, Dev. Biol., 263: 153-164, 2003
Identification of a potent peptide antagonist to an active laminin-1 sequence that blocks angiogenesis and tumor growth, Lourdes, M. P., Hibino, S., Lebioda, A. M., Mochizuki, M., Nomizu, M., and Kleinman, H. K, Cancer Res., 63: 5060-5064, 2003
Laminin-1 peptide-conjugated chitosan membranes as a novel approach for cell engineering, Mochizuki, M., Kadoya, Y., Wakabayashi, Y., Kato, K., Okazaki, I., Yamada, M., Sato, T., Sakairi, N., Nishi, N., and Nomizu, M, FASEB J., 17: 875-877, 2003
Ile-Lys-Val-Ala-Val (IKVAV)-containing laminin alpha1 chain peptides form amyloid-like fibrils, Yamada, M., Kadoya, Y., Kasai, S., Kato, K., Mochizuki, M., Nishi, N., Watanabe, N., Kleinman, H. K., Yamada, Y., and Nomizu, M, FEBS Letters, 530: 48-52, 2002
Identification of Neurite Outgrowth Promoting Sites on the Laminin alpha3 Chain G Domain, Kato, K., Utani, A., Suzuki, N., Mochizuki, M., Yamada, M., Nishi, N., Matsuura, H., Shinkai, H., and Nomizu, M, Biochemistry, 41: 10747-10753, 2002
Inhibition of Hair Follicle Growth by a Laminin-1 G-Domain Peptide, RKRLQVQLSIRT, in and Organ Culture of Isolated Vibrissa Rudiment., Hayashi, K., Mochizuki, M., Nomizu, M., Uchinuma, E., Yamashina, S., and Kadoya, Y, J. Invest. Dermatol., 118: 712-718, 2002
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Scientist