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Mirjam Münch
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Ph.D.
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office(s):
LE1103
phone(s): [+41 21 69] 35556
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RESEARCH INTEREST
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Optimal light conditions are not only for vision but also to entrain the endogenous biological clock in humans. As we spend a fair amount of our time inside of buildings, the interaction of circadian rhythms and sleep in determining daily patterns of human physiology and performance becomes an important research topic in building science. We are interested in the physiological and neurobehavioral responses to light in humans. Thereby, the endogenous biological clock and the novel photo receptors in the retinal ganglion cells play a pivotal role. We are investigating the effects of (day-)light in the laboratory and in the field.
For more information see Impact of Light on Humans.
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BIBLIOGRAPHY
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Original Articles (in chronological order):
2012
Münch M, Linhart F, Borisuit A, Jaeggi SM, Scartezzini JL. Effects of prior light exposure on cognitive performance, subjective sleepiness, and hormonal secretion in the evening. Behavioral Neuroscience.2012 Feb;126(1):196-203. Epub 2011 Dec 26.
Frey S, Birchler-Pedross A, Hofstetter M, Brunner P, Götz T, Münch M, Blatter K, Knoblauch V, Wirz-Justice A, Cajochen C. Young women with major depression live on higher homeostatic sleep pressure than healthy controls. Chronobiology International (in press).
2011:
Chellappa S, Münch M, Knoblauch V, Cajochen C. Age effects on spectral electroencephalogram activity prior to dream recall. Journal of Sleep Research.
2011 Aug 18. doi: 10.1111/j.1365-2869.2011.00947.x. [Epub ahead of print]
Münch M, Scheuermaier KD, Zhang R, Dunne SP, Guzik A, Silva EJ, Ronda JM, Duffy JF. Effects on subjective and objective alertness and sleep in response to evening light exposure in older subjects. Behavioural Brain Research. 2011 Oct 31;224(2):272-8. Epub 2011 Jun 1.
Duffy JF, Cain SW, Chang AM, Phillips AJK, Münch MY, Gronfier C, Wyatt JK, Dijk DJ, Wright KP, Czeisler CA. Quantification of Behavior Sackler Colloquium: Sex difference in the near-24-hour intrinsic period of the human circadian timing system.Proceedings of the National Academy of Sciences of the USA. 2011 Sep 13;108 Suppl 3:15602-8. Epub 2011 May 2.
2010:
Sundaram P, Wells WM, Mulkern RV, Bubrick EJ Bromfield EB, Münch M, Orbach DB. Fast human brain magnetic resonance responses associated with epileptiform spikes. Magnetic Resonance in Medicine. 2010, 64(6):1728-38.
Münch M, Silva EJ, Ronda JM, Czeisler CA, Duffy JF. EEG sleep spectra in older adults across all circadian phases during NREM sleep. Sleep 2010, 33(3):389-401.
2009:
Chellappa SL, Münch M, Blatter K, Knoblauch V, Cajochen C. Does the circadian modulation of dream recall modify with age? Sleep. 2009, 32(9): 1201-1209.
O’Donnell D, Silva EJ, Münch M, Ronda JM, Wang W, Duffy JF. Comparison of subjective and objective assessments of sleep in healthy older subjects without sleep complaints. J. Sleep Res. 2009, 18(2): 254-263.
Birchler-Pedross A, Schröder C, Münch M, Knoblauch V, Blatter K, Schnitzler-Sack C, Wirz-Justice A, Cajochen C. Subjective well-being is modulated by circadian phase, sleep pressure, age and gender. J Biol Rhythms. 2009, 24(3):232-242.
Späti J, Münch M, Blatter K, Knoblauch V, Jones LA, Cajochen C. Impact of age, sleep pressure and circadian phase on time-of-day estimates. Beh Brain Res. 2009, 201: 48-52.
2007:
Münch M, Knoblauch V, Blatter K, Wirz-Justice A, Krauchi K, Cajochen C. Homeostatic sleep regulation under low sleep pressure: are there age effects? Sleep 2007, 30(6): 781-92.
2006:
Schmidt C, Peigneux P, Muto V, Schenkel M, Knoblauch V, Münch M, De Quervain D, Wirz-Justice A, Cajochen C. Encoding difficulty promotes post-learning changes in sleep spindle activity during napping. J Neurosci 2006 26(35): 8976-82.
Münch M, Kobialka S, Steiner R, Oelhafen P, Wirz-Justice A, Cajochen C. Wavelength-dependent effects of light on sleep architecture and sleep EEG power density in men. Am J Physiol Reg Comp Endocrinol 2006, 290: R1421-28.
Blatter K, Graw P, Münch M, Knoblauch V, Wirz-Justice A, Cajochen C. Gender and age differences in psychomotor vigilance performance under differential sleep pressure conditions. Behav Brain Res 2006, 168:312-7.
Cajochen C, Jud C, Münch M, Kobialka S, Wirz-Justice A, Albrecht U. Evening exposure to blue light stimulates the expression of the clock gene PER 2 in humans. Eur J Neurosci 2006, 23: 1082-86.
2005:
Blatter K, Opwis K, Münch M, Wirz-Justice A, Cajochen C. Sleep loss-related decrements in planning performance in healthy elderly depend on task difficulty. J Sleep Res 2005, 14: 409-17.
Knoblauch V, Münch M, Blatter K, Martens WL, Schroder C, Schnitzler C, Wirz-Justice A, Cajochen C. Age-related changes in the circadian modulation of sleep spindle frequency during nap sleep. Sleep 2005, 28: 1093-01.
Münch M, Knoblauch V, Blatter K, Schroder C, Schnitzler C, Krauchi K, Wirz-Justice A, Cajochen C. Age-related attenuation of the evening circadian arousal signal in humans. Neurobiol Aging 2005, 26: 1307-19.
Neusser M, Münch M, Anzenberger G, Muller S. Investigation of marmoset hybrids (Cebuella pygmaea x Callithrix jacchus) and related Callitrichinae (Platyrrhini) by cross-species chromosome painting and comparative genomic hybridization. Cytogenet Genome Res 2005, 108: 191-6.
Cajochen C, Münch M, Kobialka S, Krauchi K, Steiner R, Oelhafen P, Orgül S, Wirz-Justice A. High sensitivity of human melatonin, alertness, thermoregulation and heart rate to short wavelength light. J Clin Endocrinol Metab 2005, 90:1311-16.
2004:
Münch M, Knoblauch V, Blatter K, Schroder C, Schnitzler C, Krauchi K, Wirz-Justice A, Cajochen C. The frontal predominance in human EEG delta activity after sleep loss decreases with age. Eur J Neurosci 2004, 20: 1402-10.
Reviews:
2010:
Münch M. Überblick dynamische Beleuchtung - Chronobiologische Beurteilung der Beleuchtungssituation (german). SEV Bulletin - Fachzeitschrift und Verbandsinformationen von electrosuisse 2010, 6: 32-36.
2006:
Cajochen C, Münch M, Knoblauch V, Blatter K, Wirz-Justice A. Age-related changes in the circadian and homeostatic regulation of human sleep. Chronobiol Int 2006, 23: 461-73.
Juda M, Münch M, Wirz-Justice A, Merrow M, Roenneberg T. Circadian clock and sleep in the elderly. Zeitschrift für Gerontopsychologie und –psychiatrie 2006, 19(1): 45-51.
2005:
Münch M, Cajochen C, Wirz-Justice A. [German; Sleep and circadian rhythms in ageing]. Z Gerontol Geriatr. 2005;38 Suppl 1:I21-3.
Meeting Proceedings:
2011:
Borisuit A, Linhart F, Kämpf J, Scartezzini J-L, Münch M. Comparison of objective and subjective visual comfort and associations with non-visual functions in young subjects. Conference Proceedings, International Scientific Conference on Renewables in a Changing Climate (CISBAT): 361-366, Lausanne, September 14-16, 2011.
Basurto C, Borisuit A, Kämpf J, Münch M, Scartezzini J-L. Daylight Optimization of buildings and application of advanced daylighting systems in central Mexico. Conference Proceedings, International Scientific Conference on Renewables in a Changing Climate (CISBAT): 397-402, Lausanne, September 14-16, 2011.
2009:
Linhart F, Scartezzini J-L, Münch M. Daylight exposure and circadian efficiency in office rooms equipped with anidolic daylighting systems. Conference Proceedings, International Scientific Conference on Renewables in a Changing Climate (CISBAT): 255-260, Lausanne, September 2-3, 2009.
Linhart F, Wittkopf S, Münch M, Scartezzini J-L. Recent research on anidolic daylighting systems: highly reflective coating materials and chronobiological properties. Proceedings OF SPIE, volume 7421-7434, pages 74230K-1-74230K-15, San Diego, California, USA, August, 2-6, 2009.
2007:
Münch MY, Cain SW, Duffy JF. Biological Rhythms Workshop IC: Sleep and rhythms. 72nd Cold Spring Harbor Symposium on quantitative Biology. 2007, 72: 35-46.
Thesis:
2006:
M. Münch: “Circadian and homeostatic sleep regulation in humans: influence of age and monochromatic light” [PhD]. Basel (Switzerland):
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EDUCATION
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1996-1998
BS (Biology), Swiss Federal Institute of Technology Zürich (CH)
1998-2002
MSc (Anthropology, Anatomy, Zoology), University of Zürich (CH)
2002-2006
PhD (Neurobiology), University of Basel (CH)
2006-2008
Post-doctoral Research Fellow, Division of Sleep Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston (USA)
2009-present
Post-doctoral Research Fellow, Solar Energy and Building Physics Laboratory, Swiss Federal Institute of Technology, Lausanne (CH)
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FINANCIAL SUPPORT
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Velux Foundation (Switzerland)
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KEYWORDS
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circadian, chronobiology, light, photoreceptors, sleep-wake cycle, human
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TEACHING
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Doctoral course (EDNE): Fall (2 ECTS credits)
Light and the built environment - impact on circadian physiology in humans
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Research Associate