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Student ETU EDOC EDBB Doctoral Assistant SV GHI UPCOL

Swapna Uplekar Doctoral Program in Biotechnology and Bioengineering PhD student nationality: Indian office(s): SV3532 phone(s): [+41 21 69] 31754 MISSION Generate an integrated regulatory map of the genome of Mycobacterium tuberculosis. MAIN PUBLICATIONS S. Uplekar, B. Heym, V. Friocourt, J. Rougemont, and S. T. Cole. Comparative genomics of Esx genes from clinical isolates of Mycobacterium tuberculosis provides evidence for gene conversion and epitope variation. Infection and immunity, 79(10):4042-9, 2011. [ DOI | Details ] M. A. Kirksey, A. D. Tischler, R. Siméone, K. B. Hisert, S. Uplekar, C. Guilhot, and J. D. McKinney. Spontaneous phthiocerol dimycocerosate-deficient variants of Mycobacterium tuberculosis are susceptible to gamma interferon-mediated immunity. Infection and immunity, 79(7):2829-38, 2011. [ DOI | Details ] A. Massouras, K. Hens, C. Gubelmann, S. Uplekar, F. Decouttere, J. Rougemont, S. T. Cole, and B. Deplancke. Primer-initiated sequence synthesis to detect and assemble structural variants. Nature Methods, 7:485-486, 2010. [ DOI | Details ] A. Massouras, K. Hens, C. Gubelmann, S. Uplekar, F. Decouttere, J. Rougemont, S. T. Cole, and B. Deplancke. Primer-initiated sequence synthesis to detect and assemble structural variants. Nature Methods, 7(7):485-486, 2010. [ DOI | Details | Full Text ] M. C. Garcia Pelayo, S. Uplekar, A. Keniry, P. Mendoza Lopez, T. Garnier, J. Nunez Garcia, L. Boschiroli, X. Zhou, J. Parkhill, N. Smith, R. G. Hewinson, S. T. Cole, and S. V. Gordon. A comprehensive survey of single nucleotide polymorphisms (SNPs) across Mycobacterium bovis strains and M. bovis BCG vaccine strains refines the genealogy and defines a minimal set of SNPs that separate virulent M. bovis strains and M. bovis BCG strains. Infection and immunity, 77(5):2230-8, 2009. [ DOI | Details ] EDUCATION 2004-2005 MRes (Master of Research), Bioinformatics, University of Newcastle-upon-Tyne, UK 2001-2004 BSc, Biochemistry with molecular biology and biotechnology, University of Bristol, UK