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Doctoral Assistant SV BMI LNMC Student ETU EDOC EDNE

Vincent Delattre Neural Microcircuitry Laboratory Engineer in Life Science and Technology (EPFL) birth date: 26.11.1983 nationality: French office(s): AI2106 phone(s): [+41 21 69] 31603 private phone: 076 521 18 99 Neocortical Microcircuits Diagnostic Thesis director: Prof. Dr. Henry Markram MISSION My thesis focuses on interfacing neural tissue with electronics. PROJECT DESCRIPTION Neuroprosthetics has a high potential to restore many crippling functions of the nervous system. The limitations to successful implementation of neuroprosthetics is understanding how to record and stimulate the brain using implanted microprocessors. The ideal interface technology for brain microchips is not yet known. Preliminary results in our lab suggest that carbon nanotubes may be an ideal interface technology. This project will explore the potential for carbon nanotubes to interface between microchips and the brain. The study will also involve simulations to explore the recording and stimulation of the neural circuits using microchips in collaboration with the Blue Brain Project. Major Techniques: · MEA (Multi Electrodes Array) stimulation and recordings of acute brain slice . Patch-clamp recordings · In vitro experimentation with carbon nanotube coated MEA MAIN PUBLICATIONS "Spontaneous cortical column recurrent activity and layer sensitivity to electrical stimulation" , V. Delattre, M. Giugliano and H. Markram, Conference proceeding at the MEA meeting 2010

Skills Technics used in the project : - patch-clamp in-vitro - MEA stimulation and recordings - modeling