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Vladimir Mlynarik office(s): CHF0628 phone(s): [+41 21 69] 37685 Select. publications V. Mlynárik, M. Vida, V. Kellö : Computer-aided N.M.R. spectra interpretation. Part 2. Minicomputer-based 13C/1H-n.m.r. file search system. Anal. Chim. Acta 122, 47-56 (1980). V. Mlynárik, L. Benes: Low temperature 13C NMR study of 1-(3-pentyloxyphenylcarbamoyloxy)-2-dialkylaminocyclohexanes. Org. Magn. Reson. 14, 536-537 (1980). T. Liptaj, V. Mlynárik, M. Remko, J. Durinda, J. Heger: 13C-NMR spectra of azachalcones. Coll. Czech. Chem. Commun. 46, 1486-1491 (1981). V. Mlynárik: Determination of one-bond 14N-13C coupling constants in amines using 13C T1rhomeasurements. Org. Magn. Reson. 17, 178-179 (1981). V. Mlynárik: Indirect measurement of nitrogen-carbon coupling constants. J. Magn. Reson. 49, 534-536 (1982). V. Mlynárik: Determination of coupling constants of nitrogen in amino group of nitroanilines by means of relaxation times in rotating frame. Coll. Czech. Chem. Commun. 48, 984-988 (1983). L. Soltés, V. Mlynárik, V. Mihálov: Demethylation in vivo of a xanthine-related respiratory analeptic, ethimizol. Xenobiotica 13, 683-687 (1983). V. Mlynárik: A study of C-35Cl coupling constants and 35Cl relaxation times through 13C relaxation in the rotating frame. Org. Magn. Reson. 22, 164-166 (1984). M. Holík, P. Pavéska, V. Mlynárik: Transfer of substituent effects in N-(p-substituted phenyl)-2,6-dimethyl-4-pyridones. J. Mol. Struct. 114, 15-20 (1984). M. Kríz, J. Kovác, V. Mlynárik: Preparation of pyridinium salts of 2-furane derivatives. Coll. Czech. Chem. Commun. 49, 2485-2491 (1984). V. Mlynárik: Coupling constants between carbon-13 and iodine-127. J. Magn. Reson. 61, 333-337 (1985). V. Mlynárik: Measurement of spin coupling constants to quadrupolar nuclei via relaxation studies. Prog. Nucl. Magn. Reson. Spectrosc. 18, 277-305 (1986). V. Mlynárik: A study of internal rotation in 2-furaldehyde through 13C relaxation times in the rotating frame. Coll. Czech. Chem. Commun. 52, 541-546 (1987). V. Mlynárik: Investigation of cross-correlation effect in scalar relaxation of the second kind. J. Magn. Reson.79, 322-324 (1988). V. Mlynárik: Measurement of scalar relaxation of multiple-quantum coherences by spin echo techniques. Chem. Phys. Letters 160, 25-28 (1989). J. Oravcová, V. Mlynárik, S. Bystrický, L. Soltés, P. Szalay, L. Bohácik, T. Trnovec: Interaction of pirprofen enantiomers with human serum albumin. Chirality 3, 412-417 (1991). S. Marchalín, V. Mlynárik, A. Stanová, D. Ilavský: Synthesis of 3-(5-alkyl-4-acetyl(ethoxycarbonyl))-2-propenoates from derivatives of 5-phenoxy-2-furylmethylene. Coll. Czech. Chem. Commun. 57, 1684-1692 (1992). V. Mlynárik, A. Degrassi, R. Toffanin, O. Jarh, F. Vittur: A method for generating magnetic resonance microimaging T2 maps with low sensitivity to diffusion. Magn. Reson. Med. 35, 423-425 (1996). V. Mlynárik, A. Degrassi, R. Toffanin, F. Vittur, M. Cova, R. S. Pozzi-Mucelli: Investigation of laminar appearance of articular cartilage by means of magnetic resonance microscopy. Magn. Reson. Imaging 14, 435-442 (1996). O. Jarh, A. Sepe, P. Jevnikar, N. Funduk, R. Toffanin, V. Mlynárik: NMR microscopy of glass-ionomer cements. In: Nuclear Magnetic Resonance Spectroscopy of Cement-based Materials (P. Colombet, A.-R. Grimmer, H. Zanni and P. Sozzani, eds.), Springer, 1998, p.369-378. E. Fragonas, V. Mlynárik, V. Jellús, F. Micali, A. Piras, R. Toffanin, R. Rizzo, F. Vittur: Correlation between biochemical composition and magnetic resonance appearance of articular cartilage. Osteoarthr. Cart. 6, 24-32 (1998). M. Cova, R. Toffanin, F. Frezza, M. Pozzi-Mucelli, V. Mlynárik, R. S. Pozzi-Mucelli, F. Vittur, L. Dalla Palma: Magnetic resonance imaging of articular cartilage: Ex vivo study on normal cartilage correlated with magnetic resonance microscopy. Eur. Radiol. 8, 1130-1136 (1998). E. Fragonas, P. Pollesello, V. Mlynárik, R. Toffanin, C. Grando, C. Godeas, F. Vittur: Sensitivity of chondrocytes of growing cartilage to reactive oxygen species. Biochim. Biophys. Acta 1425, 103-111 (1998). S.F. Keevil, B. Barbiroli, J.C.W. Brooks, E.B. Cady, R. Canese, P. Carlier, D.J. Collins, P. Gilligan, G. Gobbi, J. Hennig, H. Kügel, M.O. Leach, D. Metzler, V. Mlynárik, E. Moser, M.C. Newbold, G.S. Payne, P. Ring, J.N. Roberts, I.J. Rowland, T. Thiel, I. Tkác, S. Topp, H.J. Wittsack, M. Wylezinska, P. Zaniol, O. Henriksen, F.Podo: Absolute metabolite quantification by in vivo NMR spectroscopy: II. A multicentre trial of protocols for in vivo localised proton studies of human brain. Magn. Reson. Imaging 16, 1093-1106 (1998). P. Latta, V. Jellús, L. Budinský, V. Mlynárik, I. Tkác, R. Luypaert: Motion artifacts reduction in DWI using navigator echoes: A robust and simple correction scheme. MAGMA 7, 21-27 (1998). V. Mlynárik, S. Kasparová, T. Liptaj, D. Dobrota, J. Horecký, V. Belan: Creatine kinase reaction rates in rat brain during chronic ischemia. MAGMA 7, 162-165 (1998). S. Trattnig, V. Mlynárik, M. Breitenseher, M. Huber, A. Zembsch, T. Rand, H. Imhof: MRI visualization of proteoglycan depletion in articular cartilage via intravenous administration of Gd-DTPA. Magn. Reson. Imaging 17, 577-583 (1999). M. Mazúr, V. Mlynárik, M. Valko, P. Pelikán: The time evolution of the sol-gel process: 29Si NMR study of hydrolysis and condensation reactions of tetramethoxysilane. Appl. Magn. Reson. 16, 547-557 (1999). V. Mlynárik, S. Trattnig, M. Huber, A. Zembsch, H. Imhof: The role of relaxation times in monitoring proteoglycan depletion in articular cartilage. J. Magn. Reson. Imaging 10, 497-502 (1999). M. Mazúr, V. Mlynárik, M. Valko, P. Pelikán: The time evolution of the sol-gel process: 29Si NMR study of the hydrolysis and condensation reactions of tetraethoxysilane. Appl. Magn. Reson. 18, 187-197 (2000). S. Kasparová, D. Dobrota, V. Mlynárik, T. N. Pham, T. Liptaj, J. Horecký, Z. Braunová, A. Gvozdjáková: A study of creatine kinase reaction in rat brain under chronic pathological conditions - Chronic ischemia and ethanol intoxication. Brain Res. Bull. 53, 431-435 (2000). S. Trattnig, M. Huber, V. Mlynárik, S. Puig, H. Imhof: Magnetic resonance imaging of articular cartilage and evaluation of cartilage diseases. Invest. Radiol. 35, 595-601 (2000). V. Mlynárik, S. Trattnig: Physicochemical properties of normal articular cartilage and its MR appearance. Invest. Radiol. 35, 589-594 (2000). V. Mlynárik, S. Gruber, Z. Starcuk, Z. Starcuk, Jr., E. Moser: Very short echo time proton MR spectroscopy of human brain with a standard transmit/receive surface coil. Magn. Reson. Med. 44, 964-967 (2000). Z. Braunová, S. Kasparová, V. Mlynárik, S. Mierisová, T. Liptaj, I. Tkác, A. Gvozdjáková: Metabolic changes in rat brain after prolonged ethanol consumption measured by 1H and 31P MRS experiments. Cell. Mol. Neurobiol. 20, 703-715 (2000). M. Krebs, M. Krssák, P. Nowotny, D. Weghuber, S. Gruber, V. Mlynárik, M. Bischof, H. Stingl, C. Fürnsinn, W. Waldhäusl, M. Roden: Free fatty acids inhibit glucose-stimulated increases of intramuscular glucose-6-phosphate concentrations in humans. J. Clin. Endocrinol. Metab. 86, 2153-2160 (2001). S. Trattnig, V. Mlynárik, B. Jung, T. Bader, I. Sulzbacher, A. Herneth, R. Gaisch, S. Puig: Bilaminar pattern of tibial condyle cartilage layer on the fat-suppressed 3D gradient echo images: artifact or structural and biochemical difference in composition of cartilage? Magn. Reson. Imaging 19, 187-192 (2001). R. Toffanin, V. Mlynárik, S. Russo, P. Szomolányi, A. Piras, F. Vittur: Proteoglycan depletion and magnetic resonance parameters of articular cartilage. Arch. Biochem. Biophys. 390, 235-242 (2001). V. Mlynárik, S. Gruber, E. Moser: Proton T1 and T2 relaxation times of human brain metabolites at 3 Tesla. NMR Biomed. 14, 325-331(2001). Z. Starcuk, jr., Z. Starcuk, V. Mlynárik, M. Roden, J. Horký, E. Moser: Low power water suppression by hyperbolic secant pulses with controlled offsets and delays (WASHCODE). J. Magn. Reson. 152, 168-178 (2001). O. Gonen, S. Gruber, B. S. Y. Li, V. Mlynárik, E. Moser: Multivoxel 3D proton spectroscopy in the brain at 1.5 versus 3 Tesla: a signal-to-noise and resolution comparison. Am. J. Neuroradiol. 22, 1727-1731 (2001). I. M. Nöbauer-Huhmann, A. Ba-Ssalamah, V. Mlynárik, M. Barth, A. Schöggl, K. Heimberger, C. Matula, A. Fog, A. Kaider, S. Trattnig: MRI contrast enhancement of brain tumors at 3 Tesla versus 1.5 Tesla. Invest. Radiol. 37, 114-119 (2002). V. Mlynárik: Magic angle effect in articular cartilage. Am. J. Roentgenol. 178, 1287 (2002). B. Plecko, S. Stöckler-Ipsiroglu, E. Schober, V. Mlynárik, G. Harrer, S. Gruber, E. Moser, D. Möslinger, H. Silgoner, O. Ipsiroglu: Oral ß-hydroxybutyrate supplementation in two patients with hyperinsulinemic hypoglycemia: Monitoring of ß-hydroxybutyrate levels in blood, CSF and in the brain by in vivo magnetic resonance spectroscopy. Pediatr. Res. 52, 301-306 (2002). S. Gruber, V. Mlynárik, E. Moser: High resolution 3D proton spectroscopic imaging of the human brain at 3 Tesla: SNR issues and application for anatomy-matched voxel sizes. Magn. Reson. Med. 49, 299-306 (2003). V. Mlynárik, I. Sulzbacher, M. Bittsanský, R. Fuiko, S. Trattnig: Investigation of apparent diffusion constant as an indicator of early degenerative disease in articular cartilage. J. Magn. Reson. Imaging 17, 440-444 (2003). S. Gruber, R. Frey, V. Mlynárik, A. Stadlbauer, A. Heiden, S. Kasper, G. J. Kemp, E. Moser: Quantification of metabolic differences in the frontal brain of depressive patients and controls obtained by 1H-MRS at 3 Tesla. Invest. Radiol. 38, 403-408 (2003). M. Barth, I. M. Nöbauer-Huhmann, J. R. Reichenbach, V. Mlynárik, A. Schöggl, C. Matula, S. Trattnig: High-resolution three-dimensional contrast-enhanced blood oxygenation level-dependent magnetic resonance venography of brain tumors at 3 Tesla: First clinical experience and comparison with 1.5 Tesla. Invest. Radiol. 38, 409-414 (2003). A. Ba-Ssalamah, I. M. Nöbauer-Huhmann, K. Pinker, N. Schibany, R. Prokesch, S. Mehrain, V. Mlynárik, A. Fog, K. Heimberger, S. Trattnig: Effect of contrast dose and field strength in the magnetic resonance detection of brain metastases. Invest. Radiol. 38, 415-422 (2003). B. Plecko, S. Stöckler-Ipsiroglu, S. Gruber, V. Mlynárik, E. Moser, J. Simbrunner, F. Ebner, G. Bernert, G. Harrer, A. Gal, D. Prayer: Degree of hypomyelination and magnetic resonance spectroscopy findings in patients with Pelizaeus Merzbacher phenotype. Neuropediatrics 34, 127-136 (2003). M. Hörmann, H. Traxler, A. Ba-Ssalamah, V. Mlynárik, M. Shodaj-Baghini, H. Kubiena, S. Trattnig: Correlative high-resolution MR-anatomic study of sciatic, ulnar, and proper palmar digital nerve. Magn. Reson. Imaging 21, 879-885 (2003). S. Trattnig, A. Ba-Ssalamah, I. M. Nöbauer-Huhmann, M. Barth, K. Pinker, V. Mlynárik: Kontrastmittelanwendung auf Hochfeld-(3 T-)MRT. Radiologe 44, 56-64 (2004). S. Wolfsberger, A. Ba-Ssalamah, K. Pinker, V. Mlynárik, T. Czech, E. Knosp, S. Trattnig: Application of three-tesla magnetic resonance imaging for diagnosis and surgery of sellar lesions. J. Neurosurg. 100, 278-286 (2004). M. Krssák, V. Mlynárik, M. Meyerspeer, E. Moser, M. Roden: 1H NMR relaxation times of skeletal muscle metabolites at 3 Tesla. MAGMA 16, 155-159 (2004). A. Rosi, S. Grande, A. M. Luciani, P. Barone, V. Mlynárik, V. Viti, L. Guidoni: 1H MRS studies of signals from mobile lipids and from lipid metabolites: comparison of the behavior in cultured tumor cells and in spheroids. NMR Biomed. 17, 76-91 (2004). M. G. Bischof, V. Mlynárik, A. Brehm, E. Bernroider, M. Krssák, E. Bauer, C. Madl, W. Waldhäusl, M. Roden: Brain energy metabolism during hypoglycaemia in healthy and Type 1 diabetic subjects. Diabetologia 47, 648-651 (2004). C. Maier, M. Riedl, M. Clodi, C. Bieglmayer, V. Mlynárik, S. Trattnig, A. Luger: Dynamic contrast-enhanced MR imaging of the stimulated pituitary gland. NeuroImage 21, 347-352 (2004). V. Mlynárik, P. Szomolányi, R. Toffanin, F. Vittur, S. Trattnig: Transverse relaxation mechanisms in articular cartilage. J. Magn. Reson. 169, 300-307 (2004). S. Trattnig, C. Plank, K. Pinker, G. Striessnig, V. Mlynárik, I. Nöbauer, S. Marlovits: Bildgebende Diagnostik von Knorpelersatztherapien. Radiologe 44, 748-755 (2004). S. Gruber, A. Stadlbauer, V. Mlynárik, B. Gatterbauer, K. Roessler, E. Moser: Proton magnetic resonance spectroscopic imaging in brain tumor diagnosis. Neurosurg. Clin. N. Am. 16, 101-114 (2005). S. Kasparová, V. Brezová, M. Valko, J. Horecký, V. Mlynárik, T. Liptaj, O. Vancová, O. Ulicná, D. Dobrota: Study of the oxidative stress in a rat model of chronic brain hypoperfusion. Neurochem. Int. 46, 601-611 (2005). K. Pinker, A. Ba-Ssalamah, S. Wolfsberger, V. Mlynárik, E. Knosp, S. Trattnig: The value of high-field MRI (3 T) in the assessment of sellar lesions. Eur. J. Radiol. 54, 327-334 (2005). N. Schibany, A. Ba-Ssalamah, S. Marlovits, V. Mlynárik, I. M. Nöbauer, G. Striessnig, M. Shodjai-Baghini, G. Heinze, S. Trattnig: Impact of high field (3.0 Tesla) magnetic resonance imaging on diagnosis of osteochondral defects in the ankle joint. Eur. J. Radiol. 55, 283-288 (2005). K. Likavcanová, D. Dobrota, T. Liptaj, N. Prónayová, V. Mlynárik, V. Belan, M. Galanda, A. Beres, J. De Riggo: In vitro study of astrocytic tumour metabolism by proton magnetic resonance spectroscopy. Gen. Physiol. Biophys. 24, 327-335 (2005). S. Kasparová, Z. Sumbalová, P. Bystrický, J. Kucharská, T. Liptaj, V. Mlynárik, A. Gvozdjáková: Effect of coenzyme Q10 and vitamin E on brain energy metabolism in the animal model of Huntington's disease. Neurochem. Int. 48, 93-99 (2006). I. M. Noebauer-Huhmann, K. Pinker, M. Barth, V. Mlynárik, A. Ba-Ssalamah, W. F. Saringer, M. Weber, T. Benesch, S. Witoszynskyj, A. Rauscher, J. R. Reichenbach, S. Trattnig: Contrast-enhanced, high-resolution, susceptibility-weighted magnetic resonance imaging of the brain: Dose-dependent optimization at 3 Tesla and 1.5 Tesla in healthy volunteers. Invest. Radiol. 41, 249-255 (2006). M. G. Bischof, A. Brehm, E. Bernroider, M. Krssák, V. Mlynárik, M. Krebs, M. Roden: Cerebral glutamate metabolism during hypoglycemia in healthy and type 1 diabetic humans. Eur. J. Clin. Invest. 36, 164-169 (2006). S. Kasparová, S. Zbýn, N. Zilka, J. Horecký, T. Liptaj, V. Mlynárik, I. Juránek: 31P Magnetic resonance spectroscopy study of brain creatine kinase in rats with moderate and severe hypertension and chronic cerebral hypoperfusion. Biologia 60 (Suppl. 17), 81-84 (2005). Z. Sumbalová, J. Kucharská, S. Kasparová, V. Mlynárik, P. Bystrický, P. Bozek, O. Ulicná, O. Vancová, R. B. Singh, A. Gvozdjáková: Brain energy metabolism in external chronic diabetes: Effect of long-term administration of coenzyme Q10 and omega-3 polyunsaturated fatty acids. Biologia 60 (Suppl. 17), 105-108 (2005). F. Riederer, M. Bittsanský, C. Schmidt, V. Mlynárik, C. Baumgartner, E. Moser, W. Serles: 1H Magnetic resonance spectroscopy at 3 T in cryptogenic and mesial temporal lobe epilepsy. NMR Biomed. 19, 544-553 (2006). V. Mlynárik, G. Gambarota, H. Frenkel, R. Gruetter: Localized short-echo-time proton MR spectroscopy with full signal-intensity acquisition. Magn. Reson. Med. 56, 065-970 (2006). M. Meyerspeer, G. J. Kemp, V. Mlynárik, M. Krssák, J. Szendroedi, P. Nowotny, M. Roden, E. Moser: Direct noninvasive quantification of lactate and high energy phosphates simultaneously in exercising human skeletal muscle by localised magnetic resonance spectroscopy. Magn. Reson. Med. 57, 654-660 (2007). F. Riederer, M. Bittsansky, E. Lehner-Baumgartner, C. Baumgartner, V. Mlynárik, S. Gruber, E. Moser, M. Kaya, W. Serles: Decrease of NAA with aging outside the seizure focus in mesial temporal lobe epilepsy – A proton-MRS-study at 3 Tesla. Brain Res. 1179, 131-139 (2007). V. Mlynárik, I. Kohler, G. Gambarota, A. Vaslin, P. Clarke, R. Gruetter: Quantitative proton spectroscopic imaging of the neurochemical profile in rat brain with microliter resolution at ultra-short echo times. Magn. Reson. Med. 59, 52-58 (2008). A. Probst, F. Modler, W. Kunzel, V. Mlynárik, S. Trattnig: Demonstration of the articular cartilage of the canine ulnar trochlear notch using high-field magnetic resonance imaging. Vet. J. 177, 63-70 (2008). L. Xin, G. Gambarota, V. Mlynárik, R. Gruetter: Proton T2 relaxation time of J-coupled cerebral metabolites in rat brain at 9.4 T. NMR Biomed. 21, 396-401 (2008). S. Gruber, K. Pinker, F. Riederer, M. Chmelík, A. Stadlbauer, M. Bittsansky, V. Mlynárik, R. Frey, W. Serles, O. Bodamer, E. Moser: Metabolic changes in the normal ageing brain: Consistent findings from short and long echo time proton spectroscopy. Eur. J. Radiol. 68, 320-327 (2008). H. Lei, V. Mlynárik, N. Just, R. Gruetter: Snapshot gradient-recalled echo-planar images of rat brains at long echo time at 9.4 T. Magn. Reson. Imaging 26, 954-960 (2008). G. Gambarota, L. Xin, C. Perazzolo, I. Kohler, V. Mlynárik, R. Gruetter: In vivo 1H NMR measurement of glycine in rat brain at 9.4 T at short echo time. Magn. Reson. Med. 60, 727-731 (2008). V. Mlynárik, C. Cudalbu, L. Xin, R. Gruetter: 1H NMR spectroscopy of rat brain in vivo at 14.1 Tesla: Improvements in quantification of the neurochemical profile. J. Magn. Reson. 194, 163-168 (2008). L. Xin, H. Frenkel, V. Mlynárik, F. D. Morgenthaler, R. Gruetter: Selective resonance suppression 1H-[13C] NMR spectroscopy with asymmetric adiabatic RF pulses. Magn. Reson. Med. 61, 260-266 (2009). G. Gambarota, R. Mekle, V. Mlynárik, G. Krueger: NMR properties of human median nerve at 3 Tesla: Proton density, T1, T2 and magnetization transfer. J. Magn. Reson. Imaging 29, 982-986 (2009). J. P. Marques, R. Maddage, V. Mlynárik, R. Gruetter: On the origin of the MR image phase contrast: An in vivo MR microscopy study of the rat brain at 14.1 T. NeuroImage 46, 345-352 (2009). R. Mekle, V. Mlynárik, G. Gambarota, M. Hergt, G. Krueger, R. Gruetter: MR spectroscopy of the human brain with enhanced signal intensity at ultra-short echo times on a clinical platform at 3 T and 7 T. Magn. Reson. Med. 61, 1279-1285 (2009). C. Cudalbu, V. Mlynárik, L. Xin, R. Gruetter: Quantification of in vivo short echo-time proton magnetic resonance spectra at 14.1 Tesla using two different approaches of modelling the macromolecule spectrum. Meas. Sci. Technol. 20, Art.No. 104034 (2009). C. Cudalbu, V. Mlynárik, L. Xin, R. Gruetter: Comparison of T1 relaxation times of the neurochemical profile in rat brain at 9.4 Tesla and 14.1 Tesla. Magn. Reson. Med. 62, 862-867 (2009). H. Lei, J. Duarte, V. Mlynárik, A. Python, R. Gruetter: Deep thiopental anesthesia alters steady-state glucose homeostasis but not the neurochemical profile of rat cortex. J. Neurosci. Res. 88, 413-419 (2010). V. Clément, D. Marino, C. Culdabu, M.-F. Hamou, V. Mlynárik, N. de Tribolet, P.-Y. Dietrich, R. Gruetter, M. E. Hegi, I. Radovanovic: Marker-independent identification of glioma-initiating cells. Nat. Methods 7, 224-228 (2010). L. Xin, V. Mlynárik, B. Lanz, H. Frenkel, R. Gruetter: 1H–[13C] NMR spectroscopy of the rat brain during infusion of [2-13C] acetate at 14.1 T. Magn. Reson. Med. 64, 334-340 (2010). N. Kunz, C. Cudalbu, V. Mlynárik, P.S. Hüppi, S.V. Sizonenko, R. Gruetter: Diffusion-weighted spectroscopy: A novel approach to determine macromolecule resonances in short-echo time 1H-MRS. Magn. Reson. Med. 64, 939-946 (2010). L. Xin, G. Gambarota, J. M. N. Duarte, V. Mlynárik, R. Gruetter: Direct in vivo measurement of glycine and the neurochemical profile in the rat medulla oblongata. NMR Biomed. 23, 1097-1102 (2010). D. Viertl, A. Bischof Delaloye, B. Lanz, C. Poitry-Yamate, R. Gruetter, V. Mlynárik, S. M. Ametamey, T. L. Ross, H.-A. Lehr, P.-A. André, F. Perillo-Adamer, M. Kosinski, Y. M. Dupertuis, F. Buchegger: Increase of [18F]FLT tumor uptake in vivo mediated by FdUrd: towards improving cell proliferation positron emission tomography. Mol. Imaging Biol. 13, 321-331 (2011). O. Marroquin Belaunzaran, M. I. Cordero, V. Setola, S. Bianchi, C. Galli, N. Bouche, V. Mlynárik, R. Gruetter, C. Sandi, J. C. Bensadoun, M. Molinari, P. Aebischer: Chronic delivery of antibody fragments using immunoisolated cell implants as a passive vaccination tool. PLoS One 6, e18268 (2011). G. H. Welsch, S. Apprich, S. Zbyn, T. C. Mamisch, V. Mlynárik, K. Scheffler, O. Bieri, S. Trattnig: Biochemical (T2, T2* and magnetisation transfer ratio) MRI of knee cartilage: feasibility at ultra-high field (7T) compared with high field (3T) strength. Eur. Radiol. 21, 1136-1143 (2011). M. F. Alf, H. Lei, C. Berthet, L. Hirt, R. Gruetter, V. Mlynárik: High-resolution spatial mapping of changes in the neurochemical profile after focal ischemia in mice. NMR Biomed., accepted 23.3.2011. V. Mlynárik, C. Cudalbu, V. Clément, D. Marino, I. Radovanovic, R. Gruetter: In vivo metabolic profiling of glioma-initiating cells using proton magnetic resonance spectroscopy at 14.1 Tesla. NMR Biomed., accepted 19.5.2011. BIOGRAPHY Education: 2002 DSc degree (physical chemistry) 1974-77 doctoral study (physical chemistry) 1969-74 Faculty of Chemical Technology, Slovak Technical University, Bratislava Previous employment: 1997-2005 Dept. of Radiology, University of Vienna, Vienna 1996-1997 Dérer Hospital, Bratislava, Magnetic Resonance Centre 1995-1996 POLY-biós Research Centre, Trieste (fellowship) 1992-1994 Dérer Hospital, Bratislava, Magnetic Resonance Centre 1977-1991 Czechoslovak Institute of Metrology, Bratislava, Department of Physical Chemistry 1974-1977 Slovak Technical University, Bratislava, Faculty of Chemical Technology, NMR Laboratory Field of research: - development of methods for MR imaging, MR microscopy, localized MR spectroscopy and high-resolution MR spectroscopic imaging - studies of the neurochemical profile in transgenic mice and in rats under normal and pathologic conditions - studies of dynamic processes and relaxation in isotropic media and in biological tissues in vitro and in vivo - multiple-quantum spectroscopy - quantitative analysis of organic reference materials Membership: - International Society for Magnetic Resonance in Medicine (from 2006) - European Society for Magnetic Resonance in Medicine and Biology (from 2002)