Bio and publications
Dr. Anastassiou holds the position of senior scientist at the Allen Institute for Brain Science (Seattle, USA) concurrently with the position of adjunct professor at the Neurology department at the University of British Columbia (Vancouver, Canada). After completing his undergraduate studies in the department of chemical engineering at ETH Zurich, Anastassiou conducted his doctoral work in the department of bioengineering at Imperial College London, under the supervision of Danny OHare and Kim H. Parker, on techniques to analyze nonlinear data collected in electrochemical experiments. From 2007 until 2013 he was postdoctoral fellow at the laboratory of Christof Koch at the California Institute of Technology (Caltech) where his work was supported by a number of national and international research funding agencies. Before joining Caltech, he also worked at the Massachusetts Institute of Technology in the department of mathematics with Martin Bazant on modeling reaction-(electro)diffusion processes occurring in the vicinity of charged surfaces. At the Allen Institute Costas leads the effort to explores how neurons in the mammalian brain integrate information and how such cooperative activity gives rise to percepts and concepts this work involves realistic, large-scale computer simulations as well as experimental slice and in vivo protocols (mainly e-phys and Ca-imaging).
J. Taxidis, C.A. Anastassiou, K. Diba & C. Koch, "Local Field Potentials Encode Place Cell Ensemble Activation during Hippocampal Sharp Wave Ripples", Neuron, 87(3), 590604, (2015)
E.W. Schomburg, A. Fernandez-Ruiz, K. Mizuseki, A. Berenyi, C.A. Anastassiou, C. Koch & G. Buzsaki, "Theta Phase Segregation of Input-Specific Gamma Patterns in Entorhinal-Hippocampal Networks", Neuron, 84(2), 470-485 (2014)
M.W. Reimann*, C.A. Anastassiou*, R. Perin, S. Hill, H. Markram & C. Koch, "A Biophysically detailed model of Neocortical Local Field Potentials predicts the Critical Role of Active Membrane Conductances", Neuron, 79(2): 375-390 (2013)
G. Buzsaki, C.A. Anastassiou & C. Koch, "The origin of extracellular fields and currents - EEG, ECoG, LFP and spikes", Nature Reviews Neuroscience, 13(6), 407-420 (2012)
C.A. Anastassiou*, R. Perin*, H. Markram & C. Koch, "Ephaptic coupling of cortical neurons", Nature Neuroscience, 14(2), 217-223 (2011)
C.A, Anastassiou, S. Montgomery, M. Barahona, G. Buzsaki, C. Koch, "The effect of spatially inhomogeneous extracellular electric fields on neurons", Journal of Neuroscience, 30(5), 1925-1936 (2010)