Anthony Vocat

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Laboratory Assistant

anthony.vocat@epfl.ch +41 21 693 40 77 https://www.epfl.ch/labs/dangelo-lab

Citizenship : Swiss

EPFL SV IBI-SV UPDANGELO
AI 1108 (Bâtiment AI)
Station 19
CH-1015 Lausanne

EPFL VPRHO DSPS COSEC-SV
AI 1108 (Bâtiment AI)
Station 19
CH-1015 Lausanne

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Administrative data

Publications

Mycobacterium tuberculosis

Spaggiari D, Desfontaine V, Cruchon S, Guinchard S, Vocat A, Blattes E, Pitteloud J, Ciullini L, Bardinet C, Ivanyuk A, Makarov V, Ryabova O, Buclin T, Cole ST, Decosterd LA,
PLoS One
Development and validation of a multiplex UHPLC-MS/MS method for the determination of the investigational antibiotic against multi-resistant tuberculosis macozinone (PBTZ169) and five active metabolites in human plasma.
Markos-Orestis Georgiadis, Violeta Kourbeli, Vaya Ioannidou, Evangelos Karakitsios, Ioannis Papanastasiou, Andrew Tsotinis, Dimitri Komiotis, Anthony Vocat, Stewart T.Cole, Martin C.Taylor, John M.Kelly
Synthesis of diphenoxyadamantane alkylamines with pharmacological interest.
Caroline S. Foo, Andréanne Lupien, Maryline Kienle, Anthony Vocat, Andrej Benjak, Raphael Sommer, Dirk A. Lamprecht, Adrie J. C. Steyn,c, Kevin Pethe, Jérémie Piton, Karl-Heinz Altmann, Stewart T. Cole
mBio
Arylvinylpiperazine Amides, a New Class of Potent Inhibitors Targeting QcrB of Mycobacterium tuberculosis
Lupien A, Vocat A, Foo CS, Blattes E, Gillon JY, Makarov V, Cole ST.
An optimized background regimen for treatment of active tuberculosis with the next-generation benzothiazinone Macozinone (PBTZ169).
Jérémie Piton, Anthony Vocat, Andréanne Lupien, Caroline Shi-Yan Foo, Olga Riabova, Vadim Makarov, Stewart T Cole.
Antimicrobial Agents And Chemotherapy
Structure-based drug design and characterization of sulfonyl-piperazine benzothiazinone inhibitors of DprE1 from Mycobacterium tuberculosis
Vlachou M, Siamidi A, Diamantidi E, Iliopoulou A, Papanastasiou I, Ioannidou V, Kourbeli V, Foscolos AS, Vocat A, Cole ST, Karalis V, Kellici T, Mavromoustakos T
Drug Research
In vitro Controlled Release from Solid Pharmaceutical Formulations of two new Adamantane Aminoethers with Antitubercular Activity (I).
Odermatt NT, Sala C, Benjak A, Kolly GS, Vocat A, Lupien A, Cole ST.
Journal of Bacteriology
Rv3852 (H-NS) of Mycobacterium tuberculosis is not involved in nucleoid compaction and virulence regulation.
Lijiang Song, Matthew Jenner, Joleen Masschelein, Cerith Jones, Matthew J. Bull, Simon R. Harris, Ruben C. Hartkoorn, Anthony Vocat, Isolda Romero-Canelón, Paul Coupland, Gordon Webster, Matthew Dunn, Rebecca Weiser, Christopher Paisey, Stewart T. Cole, Julian Parkhill, Eshwar Mahenthiralingam, and Gregory L. Challis
Discovery and biosynthesis of gladiolin: a Burkholderia gladioliantibiotic with promising activity against Mycobacterium tuberculosis
Elena G. Salina,, Olga Ryabova, Anthony Vocat, Boris Nikonenko, Stewart T. Cole, Vadim Makarov
New 1-hydroxy-2-thiopyridine derivatives active against both replicating and dormant Mycobacterium tuberculosis
Foscolos AS, Papanastasiou I, Tsotinis A, Kolocouris N, Foscolos GB, Vocat A, Cole ST.
Synthesis of adamantane aminoethers with anti tubercular potential-
Singh V, Dhar N, Pató J, Kolly GS, Korduláková J, Forbak M, Evans JC, Székely R, Rybniker J, Palčeková Z, Zemanová J, Santi I, Signorino-Gelo F, Rodrigues L, Vocat A, Covarrubias AS, Rengifo MG, Johnsson K, Mowbray S, Buechler J, Delorme V, Brodin P, Knott GW, Aínsa JA, Warner DF, Kéri G, Mikušová K, McKinney JD, Cole ST, Mizrahi V, Hartkoorn RC
Identification of aminopyrimidine-sulfonamides as potent modulators of Wag31-mediated cell elongation in mycobacteria.
Vinayak Singh, Stefano Donini, Angela Pacitto, Claudia Sala, Ruben C Hartkoorn, Neeraj Dhar, György Kéri, David B. Ascher, Guillaume Mondesert, Anthony Vocat, Andréanne Lupien, Raphael Sommer, Hélène Vermet, Sophie Lagrange, Joe Buechler, Digby F. Warner, John D. McKinney, Janos Pato, Stewart T. Cole, Tom L. Blundell, Menico Rizzi, and Valerie Mizrahi
The inosine monophosphate dehydrogenase, GuaB2, is a vulnerable new bactericidal drug target for tuberculosis
Galina Karabanovich, Júlia Zemanová, Tomáš Smutný, Rita Székely, Michal Šarkan, Ivana Centárová, Anthony Vocat, Ivona Pávková, Patrik Čonka, Jan Němeček, Jiřina Stolaříková∥, Marcela Vejsová, Kateřina Vávrová, Věra Klimešová, Alexandr Hrabálek, Petr Pávek, Stewart T. Cole, Katarína Mikušová, and Jaroslav Roh
Development of 3,5-Dinitrobenzylsulfanyl-1,3,4-Oxadiazoles and Thiadiazoles as Selective Antitubercular Agents Active Against Replicating and Nonreplicating Mycobacterium tuberculosis
Jan Rybniker, Anthony Vocat, Claudia Sala, Philippe Busso, Florence Pojer, Andrej Benjak & Stewart T. Cole
Lansoprazole is an antituberculous prodrug targeting cytochrome bc1
Vadim Makarov, João Neres, Ruben C. Hartkoorn, Olga B. Ryabova, Elena Kazakova, Michal Šarkan, Stanislav Huszár, Jérémie Piton, Gaëlle S. Kolly, Anthony Vocat, Trent M. Conroy, Katarína Mikušová, and Stewart T. Cole
The 8-Pyrrole-Benzothiazinones Are Noncovalent Inhibitors of DprE1 from Mycobacterium tuberculosis
Vocat A, Hartkoorn RC, Lechartier, Zhang, Dhar N, Cole ST, Sala C
Bioluminescence for Assessing Drug Potency against Nonreplicating Mycobacterium tuberculosis
Jan Rybniker, Jeffrey M. Chen, Claudia Sala, Ruben C. Hartkoorn, Anthony Vocat, Andrej Benjak, Stefanie Boy-Röttger, Ming Zhang, Rita Székely, Zoltán Greff, László Őrfi, István Szabadkai, János Pató, György Kéri, Stewart T. Cole
Anticytolytic Screen Identifies Inhibitors of Mycobacterial Virulence Protein Secretion
Kolly G, Sala C, Vocat A, Cole ST.
Assessing essentiality of transketolase in Mycobacterium tuberculosis using an inducible protein degradation system.
David Atlbesa-Jove,́ Laurent R. Chiarelli, Vadim Makarov, Maria Rosalia Pasca, Saioa Urresti, Giorgia Mori, Elena Salina, Anthony Vocat, Natalia Comino, Elisabeth Mohorko, Svetlana Ryabova, Bernhard Pfeiffer, Ana Luisa de Jesus Lopes Ribeiro, Ane Rodrigo-Unzueta, Montse Tersa, Giuseppe Zenoni, Silvia Buroni, Karl-Heinz Altmann, Ruben C. Hartkoorn, Rudi Glockshuber, Stewart T. Cole, Giovanna Riccardi and Marcelo E. Guerin
Rv2466c Mediates the Activation of TP053 To Kill Replicating and Non-replicating Mycobacterium tuberculosis
Ming Zhang, Claudia Sala, Neeraj Dhar, Anthony Vocat, Vasan K Sambandamurthy, Sreevalli Sharm, Gwendolyn Marriner, V. Balasubramanian and Stewart T. Cole
In Vitro and In Vivo Activities of Three Oxazolidinones against Nonreplicating Mycobacterium tuberculosis
Vadim Makarov, Benoit Lechartier, Ming Zhang, João Neres,Astrid M Sar, Susanne A Raadsen, Ruben C Hartkoorn, Olga B Ryabova, Anthony Vocat, Laurent A Decosterd, Nicolas Widmer, Thierry Buclin, Wilbert Bitter, Koen Andries, Florence Pojer, Paul J Dyson and Stewart T Cole
Towards a new combination therapy for tuberculosis with next generation benzothiazinones