LMNN publications

O. Khalaf, B. Fauvet, A. Oueslati, I. Dikiy and A.-L. Mahul-Mellier et al. The H50Q Mutation Enhances alpha-Synuclein Aggregation, Secretion, and Toxicity, in Journal Of Biological Chemistry, vol. 289, num. 32, p. 21856-21876, 2014.Detailed record - View at publisherB. C. D. Fauvet, H. Lashuel (Dir.). Protein semisynthesis and total synthesis approaches to elucidate the role of Alpha-Synuclein post-translational modifications. EPFL, Lausanne, 2014.Detailed record - View at publisherA.-L. Mahul-Mellier, B. Fauvet, A. Gysbers, I. Dikiy and A. Oueslati et al. c-Abl phosphorylates ?-synuclein and regulates its degradation: implication for ?-synuclein clearance and contribution to the pathogenesis of Parkinson's disease, in Human molecular genetics, vol. 23, num. 11, p. 2858-79, 2014.Detailed record - View at publisherA. W. Schmid, B. Fauvet, M. Moniatte and H. A. Lashuel. Alpha-synuclein Post-translational Modifications as Potential Biomarkers for Parkinson Disease and Other Synucleinopathies, in Molecular & Cellular Proteomics, vol. 12, num. 12, p. 3543-3558, 2013.Detailed recordM. Haj-Yahya, B. Fauvet, Y. Herman-Bachinsky, M. Hejjaoui and S. N. Bavikar et al. Synthetic polyubiquitinated ?-Synuclein reveals important insights into the roles of the ubiquitin chain in regulating its pathophysiology, in Proceedings of the National Academy of Sciences of the United States of America, vol. 110, num. 44, p. 17726-31, 2013.Detailed record - Full Text - View at publisherB. Fauvet, S. M. Butterfield, J. Fuks, A. Brik and H. A. Lashuel. One-pot total chemical synthesis of human ?-synuclein, in Chemical communications (Cambridge, England), vol. 49, num. 81, p. 9254-6, 2013.Detailed record - Full Text - View at publisherB. Fauvet, S. M. Butterfield, J. Fuks, A. Brik and H. A. Lashuel. One-pot total chemical synthesis of human ?-synuclein, in Chemical communications (Cambridge, England), vol. 49, num. 81, p. 9254-6, 2013.Detailed record - Full Text - View at publisherF. El-Turk, B. Fauvet, A. Ashrafi, H. Ouertatani-Sakouhi and M.-K. Cho et al. Characterization of Molecular Determinants of the Conformational Stability of Macrophage Migration Inhibitory Factor: Leucine 46 Hydrophobic Pocket, in PLoS ONE, vol. 7, num. 9, p. e45024, 2012.Detailed record - Full Text - View at publisherB. Fauvet, M.-B. Fares, F. Samuel, I. Dikiy and A. Tandon et al. Characterization of semisynthetic and naturally N?-acetylated ?-synuclein in vitro and in intact cells: implications for aggregation and cellular properties of ?-synuclein, in The Journal of biological chemistry, vol. 287, num. 34, p. 28243-62, 2012.Detailed record - Full Text - View at publisherB. Fauvet, M. K. Mbefo, M.-B. Fares, C. Desobry and S. Michael et al. ?-Synuclein in central nervous system and from erythrocytes, mammalian cells, and Escherichia coli exists predominantly as disordered monomer, in The Journal of biological chemistry, vol. 287, num. 19, p. 15345-64, 2012.Detailed record - Full Text - View at publisherM. Hejjaoui, S. Butterfield, B. Fauvet, F. Vercruysse and J. Cui et al. Elucidating the role of C-terminal post-translational modifications using protein semisynthesis strategies: ?-synuclein phosphorylation at tyrosine 125, in Journal of the American Chemical Society, vol. 134, num. 11, p. 5196-210, 2012.Detailed record - Full Text - View at publisherS. Butterfield, M. Hejjaoui, B. Fauvet, L. Awad and H. A. Lashuel. Chemical strategies for controlling protein folding and elucidating the molecular mechanisms of amyloid formation and toxicity, in Journal of molecular biology, vol. 421, num. 2-3, p. 204-36, 2012.Detailed record - Full Text - View at publisherB. Fauvet, S. M. Butterfield, M. Hejjaoui, D. Olschewski and M. Prudent et al. Semisynthesis and Total Chemical Synthesis of alpha-synuclein to study Post-Translational Modifications in Health and Disease. 22nd American Peptide Symposium, San Diego, CA, 2011.Detailed recordY. Lu, M. Prudent, B. Fauvet, H. A. Lashuel and H. H. Girault. Phosphorylation of alpha-Synuclein at Y125 and S129 Alters Its Metal Binding Properties: Implications for Understanding the Role of alpha-Synuclein in the Pathogenesis of Parkinson's Disease and Related Disorders, in Acs Chemical Neuroscience, vol. 2, num. 11, p. 667-675, 2011.Detailed record - Full Text - View at publisherH. Ouertatani-Sakouhi, F. El-Turk, B. Fauvet, M.-K. Cho and D. Pinar Karpinar et al. Identification and characterization of novel classes of macrophage migration inhibitory factor (MIF) inhibitors with distinct mechanisms of action, in The Journal of biological chemistry, vol. 285, num. 34, p. 26581-98, 2010.Detailed record - Full Text - View at publisherF. El Turk, B. Fauvet, H. Ouertatani-Sakouhi, A. Lugari and S. Betzi et al. An integrative in silico methodology for the identification of modulators of macrophage migration inhibitory factor (MIF) tautomerase activity, in Bioorganic & medicinal chemistry, vol. 18, num. 14, p. 5425-40, 2010.Detailed record - Full Text - View at publisherH. Ouertatani-Sakouhi, F. El-Turk, B. Fauvet, T. Roger and D. Le Roy et al. A new class of isothiocyanate-based irreversible inhibitors of macrophage migration inhibitory factor, in Biochemistry, vol. 48, num. 41, p. 9858-70, 2009.Detailed record - Full Text - View at publisherB. Fauvet, H. Lashuel (Dir.). Developing Novel Tools for Elucidating the Structure-Function Relationship of Macrophage Migration Inhibitory Factor. , 2008.Detailed recordO. Burri, M. Mouthon and B. Fauvet, L. Kaufmann and K. Skuza (Dirs.). Réception par des psychiatres d'un reportage télévisuel sur la folie . , 2007.Detailed record