Yoon Seok Kim

EPFL SV IBI-SV UPKIM
AI 2149 (Bâtiment AI)
Station 19
1015 Lausanne

EPFL SV IBI-SV UPKIM
AI 2149 (Bâtiment AI)
Station 19
1015 Lausanne

Curriculum vitae

2025-present Assistant Professor of Life Science Engineering, EPFL
2021-2025 Postdoctoral Researcher in Neurology, Stanford University
  •     Advisor: Michelle Monje, MD., PhD

2014-2020 Ph.D. in Bioengineering, Stanford University
  •     Advisors: Karl Deisseroth, M.D., Ph.D., and Brian Kobilka, M.D.
2010-2012 Military Service, South Korean Army
2007-2014 Combined B.S. and M.S. in Biology, Stanford University

Selected publications

Neuroligin-3 interaction with CSPG4 regulates normal and malignant glial precursors through mechanotransduction

Kim YS*#, Gillespie SM*, et al.,
Published in Biorxiv (In revision in Nature Neuroscience) in 2025

Structural basis for ion selectivity in potassium-selective channelrhodopsins

Kim YS*, Tajima S*, et al.,
Published in Cell in 2023

Structural basis for channel conduction in the pump-like channelrhodopsin ChRmine

Kishi KE*, Kim YS*, Fukuda M*, Inoue M*, Kusakizako T*, Wang PY*, et al.,
Published in Cell in 2022

Comprehensive dual- and triple-feature intersectional single-vector delivery of diverse functional payloads to cells of behaving mammals

Fenno LE*, Ramakrishnan C*, Kim YS* et al.,
Published in Neuron in 2020

Genetically-targeted Chemical Assembly of Functional Materials in Living Cells, Tissues and Animals

Liu J*, Kim YS*, Richardson C*, Tom A* et al.,
Published in Science in 2020

Cortical Layer-specific Critical Dynamics Triggering Perception

Marshel JH*, Kim YS*, Machado TA*, Quirin S* et al.,
Published in Science in 2019

Crystal structure of the natural anion-conducting channelrhodopsin GtACR1

Kim YS*, Kato HE* et al.,
Published in Nature in 2018

Structural mechanisms of selectivity and gating in anion channelrhodopsins

Kim YS*, Kato HE* et al.,
Published in Nature in 2018

Research

Current Research Fields

Our lab integrates structural and functional studies, protein engineering, and cell/molecular biology to address fundamental and translational challenges in neuroscience. By combining expertise across molecular biology, protein and chemical engineering, and neurobiology, we strive to develop cutting-edge solutions for pressing neurobiological questions, including optogenetics and cancer neuroscience.

Teaching & PhD

PhD Students

Zeynep Defne Lüleci