Georges Wagnières
Senior Scientist
georges.wagnieres@epfl.ch +41 21 693 31 20 https://lifmet.epfl.ch/wagnieres/
Citizenship: Swiss
EPFL SB IPHYS LIFMET
PH L1 490 (Bâtiment PH)
Station 3
1015 Lausanne
Web site: Web site: https://lifmet.epfl.ch/
EPFL SB IPHYS LIFMET
PH L1 490 (Bâtiment PH)
Station 3
1015 Lausanne
Web site: Web site: https://www.epfl.ch/schools/sb/scgc/
EPFL SB IPHYS LIFMET
PH L1 490 (Bâtiment PH)
Station 3
1015 Lausanne
Web site: Web site: https://sph.epfl.ch/
EPFL SB IPHYS LIFMET
PH L1 490 (Bâtiment PH)
Station 3
1015 Lausanne
Web site: Web site: https://sv.epfl.ch/education
Fields of expertise
- Photodynamic therapy (PDT).
- Photobiomodulation.
- Biomedical optical spectroscopy and imaging.
- Light dosimetry.
- Preclinical and clinical development of photosensitizers and photodiagnostic instruments.
- Tissue Optics.
- Technology transfer and entrepreneurship.
Mission
- Research and teaching in the field of biomedical optics and photomedicine- Technology transfer
Biography
Georges Wagnières received his diploma degree (MSc) in physics from the University of Lausanne, Switzerland, in 1986. He obtained his doctorate in science (PhD) in physics (Biomedical optics) from the Swiss Federal Institute of Technology at Lausanne (EPFL) in 1992 and did a postdoctoral work in the Wellman Laboratories of Photomedicine (Harvard Medical School), Boston, USA, from 1993 to 1994. He also obtained a Master degree in Management of Technology delivered by the Ecole des Hautes Etudes Commerciales (HEC) of Lausanne University and the EPFL in 2001.Georges Wagnières manages a research group active in the fields of:
- Detection of early superficial cancers by fluorescence imaging.
- Characterization of early superficial cancers by high magnification narrow band imaging.
- In vivo and in vitro measurement of the vascular and tissular oxygen concentration by time-resolved luminescence spectroscopy and imaging.
- Preclinical and clinical study of new photosensitizers for photodynamic therapy (PDT).
- Treatment of neurodegenerative conditions (Alzheimer, Parkinson's diseases) by photobiomodulation.
- Preclinical and clinical photodynamic therapy of inflammatory bowel diseases and atheroscerotic plaque.
- Improvement of the selective vascular extravasation of chemotherapeutic agents by PDT.
- Monitoring the light dosimetry during PDT by fluorescence spectroscopy and imaging.
- Monitoring laser treatments of the retina by reflectance imaging.
- Light dosimetry and tissue optical spectroscopy.
- Radiometry.
- Development of light delivery systems for biomedical applications.
Georges Wagnières is also co-founder and was chairman of one spin-off companies:
- Medlight SA, founded in July 1997, which develops, produces and commercializes light distributors for photodynamic therapy.
Georges Wagnières has currently authored more than 235 papers (more than 150 in international journals with review board) and is inventor of 18 patents. He supervised 12 PhD students up to now, and currently teaches biomedical optics and photomedicine in master programs and doctoral schools. In addition, he gives the course entitled "Physique Générale I" to biology first year students registered to the Biology School of the Lausanne's University.
MAIN PUBLICATIONS
Please visit: https://www.epfl.ch/labs/lifmet/wagnieres/publications/
GROUP HOMEPAGE
https://www.epfl.ch/labs/lifmet/wagnieres/START-UP
Medlight SAhttp://www.medlight.com/
Past PhD students (co-) supervised
Dögnitz NoraGabrecht Tanja
Glanzmann Thomas
Mizeret Jérôme
Nowak-Sliwinska Patrycja
Lovisa Blaise
Piffaretti Filippo
Santhakumar Kannappan
Stepinac Thomas
Uehlinger Pascal
Zellweger Matthieu
File Upload
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Infoscience publications
Infoscience
2023
[222] Effect of Photobiomodulation on Protein Kinase C delta, Cytochrome C, and Mitochondria in U87 MG Cells
Cells
2023-05-22
DOI : 10.3390/cells12101441
[221] Porphyrin metalla-assemblies coupled to cellulose nanocrystals for PDT and imaging applications
Journal Of Porphyrins And Phthalocyanines
2023-05-05
DOI : 10.1142/S1088424623500499
2022
[220] Sodium thiosulfate, a source of hydrogen sulfide, stimulates endothelial cell proliferation and neovascularization
Frontiers In Cardiovascular Medicine
2022-10-03
DOI : 10.3389/fcvm.2022.965965
[219] Optimization of the Distance between Cylindrical Light Distributors Used for Interstitial Light Delivery in Biological Tissues
Photonics
2022-09-01
DOI : 10.3390/photonics9090597
[218] Photobiomodulation and photodynamic therapy-induced switching of autophagy and apoptosis in human dermal fibroblasts
Journal Of Photochemistry And Photobiology B-Biology
2022-09-01
DOI : 10.1016/j.jphotobiol.2022.112539
[217] Cathepsin B-Cleavable Polymeric Photosensitizer Prodrug for Selective Photodynamic Therapy: In Vitro Studies
Pharmaceuticals
2022-05-01
DOI : 10.3390/ph15050564
[216] Identification of excimer delayed fluorescence by Protoporphyrin IX: A novel access to local chromophore concentration?
Journal Of Photochemistry And Photobiology B-Biology
2022-04-01
DOI : 10.1016/j.jphotobiol.2022.112408
2021
[215] Stimulation and homogenization of the protoporphyrin IX endogenous production by photobiomodulation to increase the potency of photodynamic therapy
Journal Of Photochemistry And Photobiology B-Biology
2021-12-01
DOI : 10.1016/j.jphotobiol.2021.112347
[214] Autophagy and Apoptosis Induced in U87 MG Glioblastoma Cells by Hypericin-Mediated Photodynamic Therapy Can Be Photobiomodulated with 808 nm Light
Biomedicines
2021-11-01
DOI : 10.3390/biomedicines9111703
[213] Understanding delayed fluorescence and triplet decays of Protoporphyrin IX under hypoxic conditions
Photochemical & Photobiological Sciences
2021-07-03
DOI : 10.1007/s43630-021-00044-8
[212] Intraocular Lens Refractive Index and Its Impact on External Surface Reflections
Journal Of Refractive Surgery
2021-06-01
DOI : 10.3928/1081597X-20210310-01
[211] Influence of Oxidative Stress on Time-Resolved Oxygen Detection by [Ru(Phen)3]2+ In Vivo and In Vitro
Molecules
2021-01-18
DOI : 10.3390/molecules26020485
[210] Sodium Thiosulfate, a Source of Hydrogen Sulfide, Promotes Angiogenesis via Metabolic Reprogramming of Endothelial Cells
2021-01-01. p. 18-18.2020
[209] Grid-aware distributed control of electric vehicle charging stations in active distribution grids
Electric Power Systems Research
2020-08-15
DOI : 10.1016/j.epsr.2020.106697
[208] A general framework for non-exponential delayed fluorescence and phosphorescence decay analysis, illustrated on Protoporphyrin IX
Journal of Photochemistry and Photobiology B-Biology
2020-08-01
DOI : 10.1016/j.jphotobiol.2020.111887
[207] Catechin reduces phototoxic effects induced by protoporphyrin IX-based photodynamic therapy in the chick embryo chorioallantoic membrane
Journal Of Biomedical Optics
2020-06-01
DOI : 10.1117/1.JBO.25.6.063807
[206] Optical Characterization of an Intra-Arterial Light and Drug Delivery System for Photodynamic Therapy of Atherosclerotic Plaque
Applied Sciences-Basel
2020-06-01
DOI : 10.3390/app10124304
[205] An objective comparison of detection and segmentation algorithms for artefacts in clinical endoscopy
Scientific Reports
2020-02-17
DOI : 10.1038/s41598-020-59413-5
[204] Comparison of autofluorescence and white-light bronchoscopies performed with the Evis Lucera Spectrum for the detection of bronchial cancers: a meta-analysis
Translational Lung Cancer Research
2020-02-01
DOI : 10.21037/tlcr.2020.01.04
2019
[203] Vascular-targeted low dose photodynamic therapy stabilizes tumor vessels by modulating pericyte contractility
Lasers In Surgery And Medicine
2019-08-01
DOI : 10.1002/lsm.23069
[202] Increase and homogenization of the endogenous production of protoporphyrin IX by photobiomodulation
2019-01-01. Conference on Medical Laser Applications and Laser-Tissue Interactions IX , Munich, GERMANY , Jun 23-24, 2019. p. 110790Q.DOI : 10.1117/12.2527082.
[201] Photoprotective effect of catechin during ALA-PDT
2019-01-01. 17th World Congress of the International-Photodynamic-Association (IPA) , Cambridge, MA , Jun 28-Jul 04, 2019. p. 11070BZ.DOI : 10.1117/12.2527278.
2018
[200] Hypericin can cross barriers in the chicken's chorioallantoic membrane model when delivered in low-density lipoproteins
Photodiagnosis And Photodynamic Therapy
2018-09-01
DOI : 10.1016/j.pdpdt.2018.07.009
2017
[199] Time-resolved imaging of oxidative stress and cell/tissue oxygenation
2017. 19th IUPAB Congress / 11th EBSA Congress , British Biophys Soc, Edinburgh, SCOTLAND , JUL 16-20, 2017. p. S367-S367.[198] Modulation of the endogenous production of protoporphyrin IX in a yeast - based model organism
2017. Conference on Optical Biopsy XV - Toward Real-Time Spectroscopic Imaging and Diagnosis , San Francisco, CA , JAN 31-FEB 01, 2017. p. 1006018.DOI : 10.1117/12.2256504.
[197] In vivo measurement of the tissue oxygenation by time-resolved luminescence spectroscopy of protoporphyrin IX: Strategies to minimize artefacts associated with photoproducts
2017. Conference on Optical Biopsy XV - Toward Real-Time Spectroscopic Imaging and Diagnosis , San Francisco, CA , JAN 31-FEB 01, 2017. p. 1006016.DOI : 10.1117/12.2256669.
[196] Negligible interaction of [Ru(Phen) 3 ] 2+ with human serum albumin makes it promising for a reliable in vivo assessment of the tissue oxygenation
Journal of Inorganic Biochemistry
2017
DOI : 10.1016/j.jinorgbio.2017.05.016
[195] Interstitial fluid pressure: A novel biomarker to monitor photo-induced drug uptake in tumor and normal tissues.
Lasers Surg. Med.
2017
DOI : 10.1002/lsm.22687
[194] Determination of the radiance of cylindrical light diffusers: design of a one-axis charge-coupled device camera-based goniometer setup
Journal Of Biomedical Optics
2017
DOI : 10.1117/1.Jbo.22.3.035004
[193] Photodynamic therapy for the treatment of atherosclerotic plaque: Lost in translation?
Cardiovascular Therapeutics
2017
DOI : 10.1111/1755-5922.12238
2016
[192] Measurement of pO2 by luminescence lifetime spectroscopy: A comparative study of the phototoxicity and sensitivity of [Ru(Phen)3]2+ and PdTCPP in vivo
Journal of Biophotonics
2016
DOI : 10.1002/jbio.201600127
[191] Optimization and characterization of the endogenous production of protoporphyrin IX in a yeast model
Journal of biomedical optics
2016
DOI : 10.1117/1.JBO.21.12.125008
[190] Effect of PpIX photoproducts formation on pO2 measurement by time-resolved delayed fluorescence spectroscopy of PpIX in solution and in vivo
Journal of photochemistry and photobiology. B, Biology
2016
DOI : 10.1016/j.jphotobiol.2016.09.022
[189] Intra-Arterial Drug and Light Delivery for Photodynamic Therapy Using Visudyne (R): Implication for Atherosclerotic Plaque Treatment
Frontiers In Physiology
2016
DOI : 10.3389/fphys.2016.00400
[188] Use of Water-Soluble Oxygen Sensors to Study the Oxygen Consumption during Photosensitization with Hypericin in Vitro and in Vivo
2016. 60th Annual Meeting of the Biophysical-Society , Los Angeles, USA , February 27 - March 2, 2016. p. 507A-508A.DOI : 10.1016/j.bpj.2015.11.2712.
[187] Study of the NIR Light Induced Effects on Neuroblastoma N2A Cells with Parkinson's-Like Features
2016. 60th Annual Meeting of the Biophysical-Society , Los Angeles, USA , February 27 - March 2, 2016. p. 470A-471A.DOI : 10.1016/j.bpj.2015.11.2519.
[186] Review of the role played by the photosensitizer's photobleaching during photodynamic therapy
Journal Of Optoelectronics And Advanced Materials
2016
2015
[185] Treatment of pleural malignancies by photo-induction combined to systemic chemotherapy: Proof of concept on rodent lung tumors and feasibility study on porcine chest cavities
Lasers In Surgery And Medicine
2015
DOI : 10.1002/lsm.22422
[184] Photobiomodulation Suppresses Alpha-Synuclein-Induced Toxicity in an AAV-Based Rat Genetic Model of Parkinson's Disease
PloS One
2015
DOI : 10.1371/journal.pone.0140880
[183] Study of the influence of over-the-counter vitamin supplement intake on urine fluorescence to optimize cancer detection by fluorescence cystoscopy
Journal Of Biomedical Optics
2015
DOI : 10.1117/1.Jbo.20.6.066011
[182] Optical properties of the deep brain in the red and NIR: changes observed under in-vivo, post-mortem, frozen and formalin-fixated conditions
2015. Conference on Medical Laser Applications and Laser-Tissue Interactions VII , Munich, GERMANY , JUN 21-23, 2015. p. 954207.DOI : 10.1117/12.2183687.
[181] Red and NIR light dosimetry in the human deep brain
Physics in Medicine and Biology
2015
DOI : 10.1088/0031-9155/60/7/2921
[180] Fluence plays a critical role on the subsequent distribution of chemotherapy and tumor growth delay in murine mesothelioma xenografts pre-treated by photodynamic therapy
Lasers in Surgery and Medicine
2015
DOI : 10.1002/lsm.22329
[179] Optical properties of rabbit brain in the red and near-infrared: changes observed under in vivo, postmortem, frozen, and formalin-fixated conditions
Journal Of Biomedical Optics
2015
DOI : 10.1117/1.Jbo.20.2.025006
2014
[178] Endosomes: Guardians Against [Ru(Phen)3]2+ Photo-action In Endothelial Cells During In Vivo pO2 Detection?
Metallomics
2014
DOI : 10.1039/C4MT00190G
[177] Temperature and oxygen-concentration dependence of singlet oxygen production by RuPhen as induced by quasi-continuous excitation
Photochemical & Photobiological Sciences
2014
DOI : 10.1039/C4PP00202D
[176] Low-Dose Vascular Photodynamic Therapy Decreases Tumor Interstitial Fluid Pressure, which Promotes Liposomal Doxorubicin Distribution in a Murine Sarcoma Metastasis Model
Translational oncology
2014
DOI : 10.1016/j.tranon.2014.04.010
[175] In vivo measurement of tissue oxygenation by time-resolved luminescence spectroscopy: advantageous properties of dichlorotris(1, 10-phenanthroline)-ruthenium(II) hydrate
Journal of Biomedical Optics
2014
DOI : 10.1117/1.JBO.19.7.077004
[174] Optical spectroscopy of the bladder washout fluid to optimize fluorescence cystoscopy with Hexvix
Journal of Biomedical Optics
2014
DOI : 10.1117/1.JBO.19.9.097002
[173] Light dose plays a critical role for the distribution of chemotherapy and tumor response in mesothelioma xenografts pre-treated by photodynamic therapy
2014. 101st Annual Congress of the Swiss-Society-of-Surgery . p. 23-23.[172] Detection of Bladder Cancer by Fluorescence Cystoscopy: From Bench to Bedside - the Hexvix Story
Handbook of Photomedicine; Taylor & Francis,2014.
p. 411-426.DOI : 10.1201/b15582-41.
[171] Study of the stability of the 5-aminolevulinic acid tyrosine ester in aqueous solution
ARKIVOC - Online Journal of Organic Chemistry
2014
DOI : 10.3998/ark.5550190.p008.469
2013
[170] Correlation between Protoporphyrin IX Fluorescence Intensity, Photobleaching, Pain and Clinical Outcome of Actinic Keratosis Treated by Photodynamic Therapy
Dermatology
2013
DOI : 10.1159/000353775
[169] Correlations between photoactivable porphyrins’ fluorescence, erythema and the pain induced by PDT on normal skin using ALA-derivatives
Photodiagnosis and Photodynamic Therapy
2013
DOI : 10.1016/j.pdpdt.2013.08.005
[168] Near-Infrared 808 nm Light Boosts Complex IV-Dependent Respiration and Rescues a Parkinson-Related pink1 Model
PLoS ONE
2013
DOI : 10.1371/journal.pone.0078562
2012
[167] Etude préclinique des effets vasculaires induits par la thérapie photodynamique de nouveaux dérivés d’acide 5-aminolevulinique
MRCT CNRS; Biophotonique, optique et diagnostic
2012
[166] Reflectance imaging of the human retina at 810 nm does not suffice to optimize the parameters of hydrodynamic rebalancing laser treatment
Journal Of Biomedical Optics
2012
DOI : 10.1117/1.Jbo.17.11.116027
[165] Real-time, in vivo measurement of tissular pO(2) through the delayed fluorescence of endogenous protoporphyrin IX during photodynamic therapy
Journal Of Biomedical Optics
2012
DOI : 10.1117/1.Jbo.17.11.115007
[164] Photoactive sawhorse-type diruthenium tetracarbonyl complexes
Inorganica Chimica Acta
2012
DOI : 10.1016/j.ica.2012.05.026
[163] Probing the Interaction Between a Surfactant-Cobalt(III) Complex and Bovine Serum Albumin
Journal of Solution Chemistry
2012
DOI : 10.1007/s10953-012-9800-0
[162] Angiogenesis inhibition by the maleimide-based small molecule GNX-686
Microvascular Research
2012
DOI : 10.1016/j.mvr.2011.10.004
2011
[161] Study of the pO2-sensitivity of the dendrimeric and free forms of Pd-meso-tetra(4-carboxyphenyl)porphyrin, incorporated or not in chitosan-based nanoparticles
Chimia
2011
DOI : 10.2533/chimia.2011.691
[160] Organometallic Ruthenium(II) Arene Compounds with Antiangiogenic Activity
Journal of Medicinal Chemistry
2011
DOI : 10.1021/jm2002074
[159] Human serum albumin binding and cytotoxicity studies of surfactant–cobalt(III) complex containing 1,10-phenanthroline ligand
Colloids and Surfaces B: Biointerfaces
2011
DOI : 10.1016/j.colsurfb.2011.03.012
[158] Low dose endoluminal photodynamic therapy improves murine T cell-mediated colitis
Endoscopy
2011
DOI : 10.1055/s-0030-1256382
2010
[157] Errata: Processing of Fluorescence Angiograms for the Quantification of Vascular Effects Induced by Anti-angiogenic Agents in the CAM model (vol 79, pg 21, 2010)
Microvascular Research
2010
DOI : 10.1016/j.mvr.2010.01.009
[156] Early stirrings of landscape genomics: Awaiting next-next generation sequencing platforms before take-off
Sustainable Improvement of Animal Production and Health; Rome: Joint FAO/IAEA Division of Nuclear Techniques in Food and Agriculture,2010.
p. 185-189.[155] Chitosan-based nanogels for selective delivery of photosensitizers to macrophages and improved retention in and therapy of articular joints
Journal Of Controlled Release
2010
DOI : 10.1016/j.jconrel.2010.02.008
[154] In vitro and in vivo photocytotoxicity of boron dipyrromethene derivatives for photodynamic therapy
Journal of Medicinal Chemistry
2010
DOI : 10.1021/jm901823u
[153] The Neovessel Occlusion Efficacy of 15(1)-hydroxypurpurin-7-lactone dimethyl ester induced with photodynamic therapy
Photochemistry and Photobiology
2010
DOI : 10.1111/j.1751-1097.2009.00684.x
[152] Angiostasis-induced vascular normalization can improve photodynamic therapy
Cellular and Molecular Life Sciences
2010
DOI : 10.1007/s00018-010-0294-x
[151] Processing of fluorescence angiograms for the quantification of vascular effects induced by anti-angiogenic agents in the CAM model
Microvascular Research
2010
DOI : 10.1016/j.mvr.2009.10.004
[150] Photodynamic Therapy Selectively Enhances Liposomal Doxorubicin Uptake in Sarcoma Tumors to Rodent Lungs
Lasers In Surgery And Medicine
2010
DOI : 10.1002/lsm.20912
[149] Fluorescence of the bladder washout fluid following cystoscopy: a preliminary study
2010. Conference on Photonic Therapeutics and Diagnostics VI , San Francisco, CA , Jan 23-25, 2010. p. 75481J.DOI : 10.1117/12.842100.
[148] Pioneers in biomedical optics: Special section honoring professor Tayyaba Hasan
Journal of Biomedical Optics
2010
DOI : 10.1117/1.3492580
[147] High-magnification vascular imaging to reject false-positive sites in situ during Hexvix® fluorescence cystoscopy
Journal of Biomedical Optics
2010
DOI : 10.1117/1.3484257
[146] Development of Minimally-Invasive Optical Methods to Individualize the Doses Used for Therapeutic Applications of Light
Lausanne, EPFL, 2010.DOI : 10.5075/epfl-thesis-4831.
[145] Endoscopic Fluorescence Imaging
Lausanne, EPFL, 2010.DOI : 10.5075/epfl-thesis-4797.
2009
[144] In vitro and in vivo studies of new photoluminescent oxygen sensors for non-invasive intravascular pO 2 measurements
2009. p. 73806N.DOI : 10.1117/12.822989.
[143] Vascular effects induced by anti-VEGF agents in the CAM model: Effect of the DMSO
2009.DOI : 10.1117/12.822967.
[142] In vivo time-resolved spectroscopy of the human bronchial early cancer autofluorescence
Journal of biomedical optics
2009
DOI : 10.1117/1.3088100
[141] Detection of early bladder carcinoma by fluorescence cystoscopy with Hexvix: optical characterization of a high magnification cystoscope
2009. Photonic Therapeutics and Diagnostics V , San Jose, CA, USA . p. 716118-716118-6.DOI : 10.1117/12.809195.
[140] Bladder cancer detection by fluorescence imaging with Hexvix®: Analysis and processing of images obtained during high magnification cystoscopy
2009. Conference on Clinical and Biomedical Spectroscopy , Munich, GERMANY , JUN 16-18, 2009.DOI : 10.1117/12.822971.
[139] Photodynamic Hair Re-Growth Inhibition With Ala Derivatives
2009. 29th Annual Conference of the American-Society-for-Laser-Medicine and Surgery , National Harbor, MD , Apr 01-05, 2009. p. 38-38.[138] Autofluorescence bronchoscopy: quantification of inter-patient variations of fluorescence intensity
Lasers in medical science
2009
DOI : 10.1007/s10103-007-0518-y
[137] Assessment of a sheep animal model to optimize photodynamic therapy with Foscan in the esophague
Lasers In Surgery And Medicine
2009
DOI : 10.1002/lsm.20844
2008
[136] Improvement of the specificity of cancer detection by autofluorescence imaging in the tracheo-bronchial tree using backscattered violet light
Photodiagnosis and photodynamic therapy
2008
DOI : 10.1016/j.pdpdt.2008.01.005
[135] Autofluorescence detection of tumors in the human lung - spectroscopical measurements in situ, in an in vivo model and in vitro
Photodiagnosis and photodynamic therapy
2008
DOI : 10.1016/j.pdpdt.2008.05.002
[134] Fluorescence cystoscopy: Perspective in clinical practice and research
Der Urologe. Ausg. A
2008
DOI : 10.1007/s00120-008-1778-2
[133] Video monitoring of neovessel occlusion induced by photodynamic therapy with verteporfin (Visudyne(r)), in the CAM model
Angiogenesis
2008
DOI : 10.1007/s10456-008-9106-4
[132] Comparison of ALA- and ALA hexyl-ester-induced PpIX depth distribution in human skin carcinoma
Journal of photochemistry and photobiology.B.Biology
2008
DOI : 10.1016/j.jphotobiol.2008.07.012
[131] Glycoside esters of 5-aminolevulinic acid for photodynamic therapy of cancer
Bioconjugate Chemistry
2008
DOI : 10.1021/bc700324r
[130] Detection of early bladder carcinoma by fluorescence cystoscopy with Hexvix(R): Improvement of the specificity by microcystoscopy
2008. p. 684218.DOI : 10.1117/12.763353.
2007
[129] Detection of early bronchial cancer by autofluorescence: Results in patients with H&N cancer
2007. p. OC1-OC8.DOI : 10.1364/ECBO.2007.6628_12.
[128] Correlations between tissular effects, PPIX fluorescence and the pain induced by PDT on normal skin
2007. 37th Annual Meeting of the European-Society-for-Dermatological-Research , Zurich, SWITZERLAND , Sep 05-08, 2007. p. S47-S47.[127] Design of an endoscopic optical reference to be used for autofluorescence bronchoscopy with a commercially available diagnostic autofluorescence endoscopy (DAFE) system
Physics in medicine and biology
2007
DOI : 10.1088/0031-9155/52/8/N02
[126] Blue-violet excited autofluorescence spectroscopy and imaging of normal and cancerous human bronchial tissue after formalin fixation
Photochemistry and photobiology
2007
DOI : 10.1562/2006-03-20-RA-852
[125] Design of a light delivery system for the photodynamic treatment of the Crohn's disease
2007.DOI : 10.1117/12.728477.
[124] Autofluorescence bronchoscopy: Clinical experience with an optimized system in head and neck cancer patients
Medical Laser Application
2007
DOI : 10.1016/j.mla.2007.09.003
[123] Optimized autofluorescence bronchoscopy using additional backscattered red light
Journal of biomedical optics
2007
DOI : 10.1117/1.2811952
[122] Improvement of the Contrast in Cancer Detection by Autofluorescence Bronchoscopy using a narrow spectral violet Excitation: A preliminary study
Biomedical Signal Processing and Control
2007
DOI : 10.1016/j.bspc.2007.07.004
[121] Detection of early bronchial cancer by autofluorescence: first clinical results with an improved system
2007
2006
[120] Photodynamic therapy as a novel therapeutic approach for the treatment of Crohn's disease
Gastroenterology
2006
[119] Improvement of the contrast in cancer detection by autofluorescence bronchoscopy using a narrow spectral violet excitation: A preliminary study
2006. p. 17-21.DOI : 10.3182/20060920-3-FR-2912.00008.
[118] Preclinical comparison of mTHPC and verteporfin for intracavitary photodynamic therapy of malignant pleural mesothelioma
European surgical research. Europäische chirurgische Forschung. Recherches chirurgicales européennes
2006
DOI : 10.1159/000094028
[117] Photothrombic activity of m-THPC-loaded liposomal formulations: pre-clinical assessment on chick chorioallantoic membrane model
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences
2006
DOI : 10.1016/j.ejps.2006.01.008
[116] On the role of iron and one of its chelating agents in the production of protoporphyrin IX generated by 5-aminolevulinic acid and its hexyl ester derivative tested on an epidermal equivalent of human skin
Photochemistry and Photobiology
2006
DOI : 10.1562/2005-12-04-RA-745
[115] Clinical fluorescence spectroscopy and imaging for the detection of early carcinoma by autofluorescence bronchoscopy and the study of the protoporphyrin IX pharmacokinetics in the endometrium
Lausanne, EPFL, 2006.DOI : 10.5075/epfl-thesis-3537.
2005
[114] Influence of the excitation wavelength on the Tumor-to-Healthy Contrast in Autofluorescence Bronchoscopy - A Comprehensive Study
2005. p. 586207.DOI : 10.1117/12.633009.
[113] Autofluorescence detection of tumors in the human lung: comparison between in-vivo and in vitro measurements
2005. p. 1-9.DOI : 10.1117/12.633011.
[112] Influence of the menstrual cycle on aminolevulinic acid induced protoporphyrin IX fluorescence in the endometrium: in vivo study
Lasers in Surgery and Medicine
2005
DOI : 10.1002/lsm.20139
[111] Preclinical evaluation of a novel water-soluble chlorin E-6 derivative (BLC 1010) as photosensitizer for the closure of the neovessels
Photochemistry and Photobiology
2005
DOI : 10.1562/2005-02-23-RA-448
[110] Photodynamic therapy and endoscopic mucosal resection as minimally invasive approaches for the treatment of early esophageal tumors: Pre-clinical and clinical experience in Lausanne
Photodiagnosis and Photodynamic Therapy
2005
DOI : 10.1016/S1572-1000(05)00035-9
[109] Light-induced retinal vascular damage by Pd-porphyrin luminescent oxygen probes
Investigative Ophthalmology & Visual Science
2005
DOI : 10.1167/iovs.04-0500
2004
[108] Méthodes optiques de mesure de la concentration d'oxygène tissulaire pour la photothérapie dynamique
Photoniques
2004
[107] Time-dependent hexaminolaevulinate induced protoporphyrin IX distribution after topical application in patients with cervical intraepithelial neoplasia: A fluorescence microscopy study
Lasers in Surgery and Medicine
2004
DOI : 10.1002/lsm.20095
[106] Photodynamic endometrial ablation for the treatment of dysfunctional uterine bleeding: A preliminary report
Lasers in Surgery and Medicine
2004
DOI : 10.1002/lsm.10244
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Lasers in Medical Science
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Research
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