Georges Wagnières

Nationality: Swiss

EPFL SB IPHYS LIFMET
PH L1 490 (Bâtiment PH)
Station 3
1015 Lausanne

EPFL SB IPHYS LIFMET
PH L1 490 (Bâtiment PH)
Station 3
1015 Lausanne

EPFL SB IPHYS LIFMET
PH L1 490 (Bâtiment PH)
Station 3
1015 Lausanne

EPFL SB IPHYS LIFMET
PH L1 490 (Bâtiment PH)
Station 3
1015 Lausanne

Expertise

- Fluorescence spectroscopy and imaging.
- Photodynamic therapy (PDT).
- Photobiomodulation.
- Biomedical optical spectroscopy and imaging.
- Light dosimetry.
- Preclinical and clinical development of photosensitizers and photodiagnostic instruments.
- Tissue Optics.
- Technology transfer and entrepreneurship.

Mission

- Research and teaching in the field of biomedical optics and photomedicine
- Technology transfer
Georges Wagnières received his diploma degree (MSc) in physics from the University of Lausanne, Switzerland, in 1986. He obtained his doctorate in science (PhD) in physics (Biomedical optics) from the Swiss Federal Institute of Technology at Lausanne (EPFL) in 1992 and did a postdoctoral work in the Wellman Laboratories of Photomedicine (Harvard Medical School), Boston, USA, from 1993 to 1994. He also obtained a Master degree in Management of Technology delivered by the Ecole des Hautes Etudes Commerciales (HEC) of Lausanne University and the EPFL in 2001.
Georges Wagnières manages a research group active in the fields of:
- Detection of early superficial cancers by fluorescence imaging.
- Characterization of early superficial cancers by high magnification narrow band imaging.
- In vivo and in vitro measurement of the vascular and tissular oxygen concentration by time-resolved luminescence spectroscopy and imaging.
- Preclinical and clinical study of new photosensitizers for photodynamic therapy (PDT).
- Treatment of neurodegenerative conditions (Alzheimer, Parkinson's diseases) by photobiomodulation.
- Preclinical and clinical photodynamic therapy of inflammatory bowel diseases and atheroscerotic plaque.
- Improvement of the selective vascular extravasation of chemotherapeutic agents by PDT.
- Monitoring the light dosimetry during PDT by fluorescence spectroscopy and imaging.
- Monitoring laser treatments of the retina by reflectance imaging.
- Light dosimetry and tissue optical spectroscopy.
- Radiometry.
- Development of light delivery systems for biomedical applications.
Georges Wagnières is also co-founder and was chairman of one spin-off companies:
- Medlight SA, founded in July 1997, which develops, produces and commercializes light distributors for photodynamic therapy.
Georges Wagnières has currently authored more than 235 papers (more than 150 in international journals with review board) and is inventor of 18 patents. He supervised 12 PhD students up to now, and currently teaches biomedical optics and photomedicine in master programs and doctoral schools. In addition, he gives the course entitled "Physique Générale I" to biology first year students registered to the Biology School of the Lausanne's University.
MAIN PUBLICATIONS
Please visit: https://www.epfl.ch/labs/lifmet/wagnieres/publications/

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GROUP HOMEPAGE

https://www.epfl.ch/labs/lifmet/wagnieres/

Past PhD students (co-) supervised


Dögnitz Nora
Gabrecht Tanja
Glanzmann Thomas
Mizeret Jérôme
Nowak-Sliwinska Patrycja
Lovisa Blaise
Piffaretti Filippo
Santhakumar Kannappan
Stepinac Thomas
Uehlinger Pascal
Zellweger Matthieu

START-UP

Medlight SA
http://www.medlight.com/

Infoscience

Teaching & PhD

Past EPFL PhD Students

Matthieu Philippe Emmanuel Zellweger, Thomas Stepinac, Pascal Uehlinger, Tanja Gabrecht, Filippo Piffaretti, Blaise Lovisa, Cyrus Kazemiraad

Courses

Biomedical optics

BIOENG-445

This course addresses the principles governing the interactions between light and biological tissue, their optical properties and basic concepts of radiometry. Illustrative diagnostic and therapeutic applications of light in medicine and photobiology will also be described.

Photomedicine

CH-448

The most important clinical diagnostic and therapeutic applications of light will be described. In addition, this course will address the principles governing the interactions between light and biological tissues, their optical properties and basic concepts in photobiology and photochemistry.