Injury-induced intestinal stem cell renewal requires capillary morphogenesis gene 2

L. Bracq; A. Chuat; B. Kunz; O. Burri; R. Guiet  et al.

Role of S-acylating enzymes in ciliated cells

D. Korotkova

Identification of the Lipid Oxygen Radical Defense pathway and its epigenetic control

F.-G. van der Goot; F. Sarmento Mesquita; L. Abrami; R. Forey; B. Kunz  et al.

INTEGRATING SUSTAINABILITY IN HIGHER EDUCATION INSTITUTIONS: A CASE STUDY FROM EPFL

V. Rossi; A. Garin; S. Der Sarkissian; J. Grazioli; G. van der Goot  et al.

Mechanisms and functions of protein S-acylation

F. S. Mesquita; L. Abrami; M. E. Linder; S. X. Bamji; B. C. Dickinson  et al.

S-acylation and lipid exchange at the ER-Golgi membrane contact sites regulate pathogen entry in human cells

M. U. Anwar

Pou5f1b inhibitors

L. Simó Riudalbas; D. Trono; L. Gouzi Abrami; G. Van Der Goot; S. Offner

SARS-CoV-2 hijacks a cell damage response, which induces transcription of a more efficient Spike S-acyltransferase

F. S. Mesquita; L. Abrami; L. Bracq; N. Panyain; V. Mercier  et al.

Dynamics of CLIMP-63 S-acylation control ER morphology

P. A. Sandoz; R. A. Denhardt-Eriksson; L. Abrami; L. A. Abriata; G. Spreemann  et al.

S-acylation: an orchestrator of the life cycle and function of membrane proteins

F. S. Mesquita; L. Abrami; A. Samurkas; F. G. van der Goot

ER-Golgi membrane contact sites control the formation of plasma membrane lipid nanodomains

M. Anwar; O. Sergeeva; L. Abrami; P. Liberali; G. D'Angelo  et al.

Refining S-acylation: Structure, regulation, dynamics, and therapeutic implications

M. U. Anwar; F. G. van der Goot

Inhibitors of acyl protein thioesterases against microbial infections

G. Van Der Goot; F. Mesquita; L. Abrami; C. Tapparel Vu; V. Cagno

Local and substrate-specific S-palmitoylation determines subcellular localization of G alpha o

G. P. Solis; A. Kazemzadeh; L. Abrami; J. Valnohova; C. Alvarez  et al.

ER-Golgi-localized proteins TMED2 and TMED10 control the formation of plasma membrane lipid nanodomains

M. U. Anwar; O. A. Sergeeva; L. Abrami; F. S. Mesquita; I. Lukonin  et al.

Akt Is S-Palmitoylated: A New Layer of Regulation for Akt

M. Blaustein; E. Piegari; C. M. Calejman; A. Vila; A. Amante  et al.

Palmitoylated acyl protein thioesterase APT2 deforms membranes to extract substrate acyl chains

L. Abrami; M. Audagnotto; S. Ho; M. J. Marcaida; F. S. Mesquita  et al.

S-acylation controls SARS-CoV-2 membrane lipid organization and enhances infectivity

F. S. Mesquita; L. Abrami; O. Sergeeva; P. Turelli; E. Qing  et al.

S-acylation by ZDHHC20 targets ORAI1 channels to lipid rafts for efficient Ca2+ signaling by Jurkat T cell receptors at the immune synapse

A. Carreras-Sureda; L. Abrami; K. Ji-Hee; W.-A. Wang; C. Henry  et al.

ANTXR2 as a novel player in skeletal muscle stem cells

S. Metti; L. J. Bracq; F. G. van der Goot; P. Bonaldo

Harnessing the Membrane Translocation Properties of AB Toxins for Therapeutic Applications

N. Piot; G. van der Goot; O. A. Sergeeva

Hemagglutinin of Influenza A, but not of Influenza B and C viruses is acylated by ZDHHC2, 8, 15 and 20

M. R. Gadalla; L. Abrami; F. G. van der Goot; M. Veit

Ligand Binding to the Collagen VI Receptor Triggers a Talin-to-RhoA Switch that Regulates Receptor Endocytosis

J. Buergi; L. Abrami; I. Castanon; L. A. Abriata; B. Kunz  et al.

Wnt-controlled sphingolipids modulate Anthrax Toxin Receptor palmitoylation to regulate oriented mitosis in zebrafish

I. Castanon; J. T. Hannich; L. Abrami; F. Huber; M. Dubois  et al.

A toxic palmitoylation of Cdc42 enhances NF-kappa B signaling and drives a severe autoinflammatory syndrome

B. Bekhouche; A. Tourville; Y. Ravichandran; R. Tacine; L. Abrami  et al.

Mammalian membrane trafficking as seen through the lens of bacterial toxins

F. S. Mesquita; F. G. van der Goot; O. A. Sergeeva

Use of deoxysphingolipids as anti-toxins and anti-virals

H. S. Riezman; J. T. Hannich; A. Galih; J. Gruenberg; F. G. Van Der Goot

Anthrax toxin requires ZDHHC5-mediated palmitoylation of its surface-processing host enzymes

O. A. Sergeeva; F. G. van der Goot

Image-based analysis of living mammalian cells using label-free 3D refractive index maps reveals new organelle dynamics and dry mass flux

P. Sandoz; C. C. G. Tremblay; G. van der Goot; M. Frechin

Aerolysin, a Powerful Protein Sensor for Fundamental Studies and Development of Upcoming Applications

B. Cressiot; H. Ouldali; M. Pastoriza-Gallego; L. Bacri; F. G. Van der Goot  et al.

Targeting STING with covalent small-molecule inhibitors

S. Haag; M. Gulen; L. Reymond; A. Gibelin; L. Abrami  et al.

Palmitoylation mediates membrane association of hepatitis E virus ORF3 protein and is required for infectious particle secretion

J. Gouttenoire; A. Pollan; L. Abrami; N. Oechslin; J. Mauron  et al.

Palmitoylation determines the subcellular localization of the hepatitis E virus ORF3 protein

J. Gouttenoire; P. Angela; A. Laurence; M. Maxime; D. T. V. Loan  et al.

Likelihood-free Inference of Population Genetic Parameters from Time-Sampled Genetic Data

H. Shim

Modeling CLiMP-63 spatio-temporal distribution and its interplay with Post-translational modification

R. A. Denhardt-Eriksson; P. Sandoz; L. Gouzi Abrami; S. Ho; B. Kunz

CMG2/ANTXR2 regulates extracellular collagen VI which accumulates in hyaline fibromatosis syndrome

J. Burgi; B. Kunz; L. Abrami; J. Deuquet; A. Piersigilli  et al.

Damage of eukaryotic cells by the pore-forming toxin sticholysin II: Consequences of the potassium efflux

S. Cabezas; S. Ho; U. Ros; M. E. Lanio; C. Alvarez  et al.

Novel systems biology approaches for design and analysis of palmitoylation networks reveal its regulatory effects on protein stability, activity and localization

T. Dallavilla

Regulation of Endoplasmic Reticulum Architecture by Protein S-Palmitoylation

P. A. Sandoz

Cryo-EM structure of aerolysin variants reveals a novel protein fold and the pore-formation process

I. Iacovache; S. De Carlo; N. Cirauqui; M. Dal Peraro; F. G. van der Goot  et al.

Cytoplasmic Ubiquitin-Specific Protease 19 (USP19) Modulates Aggregation of Polyglutamine-Expanded Ataxin-3 and Huntingtin through the HSP90 Chaperone

W.-T. He; X.-M. Zheng; Y.-H. Zhang; Y.-G. Gao; A.-X. Song  et al.

Intrinsic Disorder in Transmembrane Proteins: Roles in Signaling and Topology Prediction

J. Burgi; B. Xue; V. N. Uversky; F. G. van der Goot

Revealing Assembly of a Pore-Forming Complex Using Single-Cell Kinetic Analysis and Modeling

M. Bischofberger; I. Iacovache; D. Boss; F. Naef; F. G. van der Goot  et al.

Ubiquitin-dependent folding of the Wnt signaling coreceptor LRP6

E. Perrody; L. Abrami; M. Feldman; B. Kunz; S. Urbe  et al.

Model-Driven Understanding of Palmitoylation Dynamics: Regulated Acylation of the Endoplasmic Reticulum Chaperone Calnexin

T. Dallavilla; L. Abrami; P. A. Sandoz; G. Savoglidis; V. Hatzimanikatis  et al.

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

D. J. Klionsky; K. Abdelmohsen; A. Abe; M. J. Abedin; H. Abeliovich  et al.

The Ins and Outs of Anthrax Toxin

S. Friebe; F. G. van der Goot; J. Buergi

Folding and Endocytosis of Anthrax Toxin Receptors

S. E. Friebe

Differential dependence on N-glycosylation of anthrax toxin receptors CMG2 and TEM8

S. Friebe; J. Deuquet; F. G. van der Goot

The SwissLipids knowledgebase for lipid biology

L. Aimo; R. Liechti; N. Hyka-Nouspikel; A. Niknejad; A. Gleizes  et al.

Kicking Out Pathogens in Exosomes

O. A. Sergeeva; F. G. van der Goot

How many lives does CLIMP-63 have?

P. A. Sandoz; F. G. Van der Goot

Unraveling the Physiological Role of Capillary Morphogenesis Gene 2 in Health and Disease

J. Bürgi

Study of mTOR palmitoylation

E. Cuenot

Live-cell multiplane three-dimensional super-resolution optical fluctuation imaging

S. Geissbuehler; A. Sharipov; A. Godinat; N. L. Bocchio; P. A. Sandoz  et al.

Novel mechanistic insights into anthrax toxin endocytosis

S. Friebe; L. Abrami; F. G. Van der Goot

Close Encounter of the Third Kind: The ER Meets Endosomes at Fission Sites

F. G. Van Der Goot; J. Gruenberg

Mechanistic effects of protein palmitoylation and the cellular consequences thereof

S. Blaskovic; A. Adibekian; M. Blanc; F. G. van der Goot

In-Depth Analysis of Mutations in Hyaline Fibromatosis Syndrome (HFS)

S. Yan

Mechanism and Function of S-palmitoylation in Capillary Morphogenesis Gene 2

S. Blaskovic

Molecular assembly of the aerolysin pore reveals a swirling membrane-insertion mechanism

M. T. Degiacomi; I. Lacovache; L. Pernot; M. Chami; M. Kudryashev  et al.

Did Cholera Toxin Finally Get Caught?

F. Martinon; F. G. van der Goot

Calnexin Controls the STAT3-Mediated Transcriptional Response to EGF

A. K. Lakkaraju; G. van der Goot

Biochemical Membrane Lipidomics during Drosophila Development

X. L. Guan; G. Cestra; G. Shui; A. Kuhrs; R. B. Schittenhelm  et al.

In-depth analysis of hyaline fibromatosis syndrome frameshift mutations at the same site reveal the necessity of personalized therapy

S. E. Yan; T. Lemmin; S. Salvi; E. Lausch; A. Superti-Furga  et al.

Anthrax toxin receptor 2a controls mitotic spindle positioning

I. Castanon; L. Abrami; L. Holtzer; C. P. Heisenberg; G. van der Goot  et al.

Hijacking Multivesicular Bodies Enables Long-Term and Exosome-Mediated Long-Distance Action of Anthrax Toxin

L. Abrami; L. Brandi; M. Moayeri; M. J. Brown; B. A. Krantz  et al.

The Molecular Assembly of the Aerolysin Pore Reveals a Unique Swirling Membrane-Insertion Mechanism

M. Degiacomi; I. Iacovache; G. Van Der Goot; M. Dal Peraro

What does S-palmitoylation do to membrane proteins?

S. Blaskovic; M. Blanc; G. van der Goot

Palmitoylation, pathogens and their host

M. Blanc; S. Blaskovic; G. van der Goot

Caspase-2 is an initiator caspase responsible for pore-forming toxin-mediated apoptosis

G. Imre; J. Heering; A.-N. Takeda; M. Husmann; B. Thiede  et al.

Binding of Lassa virus perturbs extracellular matrix-induced signal transduction via dystroglycan

J. M. Rojek; M.-L. Moraz; C. Pythoud; S. Rothenberger; G. van der Goot  et al.

The dark sides of capillary morphogenesis gene 2

J. Deuquet; E. Lausch; A. Superti-Furga; G. van der Goot

Pathogenic Pore-Forming Proteins: Function and Host Response

M. Bischofberger; I. Iacovache; G. van der Goot

Hyaline Fibromatosis Syndrome inducing mutations in the ectodomain of anthrax toxin receptor 2 can be rescued by proteasome inhibitors

J. Deuquet; E. Lausch; N. Guex; L. Abrami; S. Salvi  et al.

Dynamics of Unfolded Protein Transport through an Aerolysin Pore

M. Pastoriza-Gallego; L. Rabah; G. Gibrat; B. Thiebot; G. van der Goot  et al.

Dual Chaperone Role of the C-Terminal Propeptide in Folding and Oligomerization of the Pore-Forming Toxin Aerolysin

I. Iacovache; M. T. Degiacomi; L. Pernot; S. Ho; M. Schiltz  et al.

Extending the aerolysin family: from bacteria to vertebrates

P. Szczesny; I. Iacovache; A. Muszewska; K. Ginalski; G. van der Goot  et al.

Monalysin, a novel ß-pore-forming toxin from the Drosophila pathogen Pseudomonas entomophila, contributes to host intestinal damage and lethality

O. Opota; I. Vallet-Gély; R. Vincentelli; C. Kellenberger; I. Iacovache  et al.

Pore-forming toxins induce multiple cellular responses promoting survival

M. R. Gonzalez; M. Bischofberger; B. Freche; S. Ho; R. G. Parton  et al.

When cells and microbes meet in Krakow

K. Rajalingam; G. van der Goot

Cellular Responses to Bacterial Pore-Forming Toxins

R. M. Gonzalez

Folding and Structure of the Pore Forming Toxin Aerolysin

M. I. Iacovache

Molecular Mechanisms Underlying Hyaline Fibromatosis Syndrome

J. Deuquet Ariosa

The 2DX robot: a membrane protein 2D crystallization Swiss Army knife

I. Iacovache; M. Biasini; J. Kowal; W. Kukulski; M. Chami  et al.

Preliminary crystallographic analysis of two oligomerization-deficient mutants of the aerolysin toxin, H132D and H132N, in their proteolyzed forms

L. Pernot; M. Schiltz; G. van der Goot

Anthrax toxin triggers the activation of src-like kinases to mediate its own uptake

L. Abrami; B. Kunz; F. G. van der Goot

Endocytosis of the anthrax toxin is mediated by clathrin, actin and unconventional adaptors

L. Abrami; M. Bischofberger; B. Kunz; R. Groux; F. G. van der Goot

A model for the assembly and activation process of the pore-forming toxin Aerolysin

M. Degiacomi; I. Iacovache; G. van der Goot; M. Dal Peraro

Structure and assembly of pore-forming proteins

I. Iacovache; M. Bischofberger; F. G. van der Goot

Getting the Opportunity to Fly on your own

G. van der Goot

Shigella phagocytic vacuolar membrane remnants participate in the cellular response to pathogen invasion and are regulated by autophagy

N. Dupont; S. Lacas-Gervais; J. Bertout; I. Paz; B. Freche  et al.

Systemic hyalinosis mutations in the CMG2 ectodomain leading to loss of function through retention in the endoplasmic reticulum

J. Deuquet; L. Abrami; A. Difeo; M. C. M. Ramirez; J. A. Martignetti  et al.

Membrane injury by pore-forming proteins

M. Bischofberger; M. R. Gonzalez; F. G. van der Goot

Novel ubiquitin-dependent quality control in the endoplasmic reticulum

M. Feldman; F. G. van der Goot

Receptors of anthrax toxin and cell entry

G. van der Goot; J. A. T. Young

Maturation modulates caspase-1-independent responses of dendritic cells to Anthrax lethal toxin

N. Reig; A. Jiang; R. Couture; F. S. Sutterwala; Y. Ogura  et al.

Activation of the unfolded protein response is required for defenses against bacterial pore-forming toxin in vivo

L. J. Bischof; C. Y. Kao; F. C. Los; M. R. Gonzalez; Z. Shen  et al.

Regulation of the V-ATPase along the endocytic pathway occurs through reversible subunit association and membrane localization

C. Lafourcade; K. Sobo; S. Kieffer-Jaquinod; J. Garin; F. G. van der Goot

Elastic membrane heterogeneity of living cells revealed by stiff nanoscale membrane domains

C. Roduit; F. G. van der Goot; P. De Los Rios; A. Yersin; P. Steiner  et al.

Hrs and SNX3 functions in sorting and membrane invagination within multivesicular bodies

V. Pons; P. P. Luyet; E. Morel; L. Abrami; F. G. van der Goot  et al.

Functional interactions between anthrax toxin receptors and the WNT signalling protein LRP6

L. Abrami; B. Kunz; J. Deuquet; A. Bafico; G. Davidson  et al.

Palmitoylation and ubiquitination regulate exit of the Wnt signaling protein LRP6 from the endoplasmic reticulum

L. Abrami; B. Kunz; I. Iacovache; F. G. van der Goot

Palmitoylation of membrane proteins (Review)

J. Charollais; F. G. Van Der Goot

Pore formation: an ancient yet complex form of attack

I. Iacovache; F. G. van der Goot; L. Pernot

Bacterial pore-forming toxins: the (w)hole story?

M. R. Gonzalez; M. Bischofberger; L. Pernot; F. G. van der Goot; B. Frêche

Exotoxin secretion: getting out to find the way in

M. Bischofberger; F. G. van der Goot

Involvement of a Golgi-resident GPI-anchored protein in maintenance of the Golgi structure

X. Li; D. Kaloyanova; M. van Eijk; R. Eerland; G. van der Goot  et al.

Late endosomal cholesterol accumulation leads to impaired intra-endosomal trafficking

K. Sobo; I. Le Blanc; P. P. Luyet; M. Fivaz; C. Ferguson  et al.

Diversity of raft-like domains in late endosomes

K. Sobo; J. Chevallier; R. G. Parton; J. Gruenberg; F. G. van der Goot

Pore-forming toxins and cellular non-immune defenses (CNIDs)

R. Aroian; F. G. van der Goot

The role of the inflammasome in cellular responses to toxins and bacterial effectors

B. Freche; N. Reig; F. G. van der Goot

Editorial Overview

P. L. Small; F. G. van der Goot

Dynamics of GPI-anchored proteins on the surface of living cells

A. Nohe; E. Keating; M. Fivaz; F. G. van der Goot; N. O. Petersen

Caspase-1 activation of lipid metabolic pathways in response to bacterial pore-forming toxins promotes cell survival

L. Gurcel; L. Abrami; S. Girardin; J. Tschopp; F. G. van der Goot

A rivet model for channel formation by aerolysin-like pore-forming toxins

I. Iacovache; P. Paumard; H. Scheib; C. Lesieur; N. Sakai  et al.

Receptor palmitoylation and ubiquitination regulate anthrax toxin endocytosis

L. Abrami; S. H. Leppla; F. G. van der Goot

Mechanisms of pathogen entry through the endosomal compartments

J. Gruenberg; F. G. van der Goot

Intra-endosomal membrane traffic

F. G. van der Goot; J. Gruenberg

About lipids and toxins

N. Reig; F. G. van der Goot

Toxoplasma: guess who's coming to dinner

J. Gruenberg; F. G. van der Goot

Aerolysin and related Aeromonas toxins

L. Gurcel; I. Iacovache; F. van der Goot

Bacterial invasion via lipid rafts

F. Lafont; F. G. van der Goot

Anthrax toxin: the long and winding road that leads to the kill

L. Abrami; N. Reig; F. G. van der Goot

Oiling the key hole

F. Lafont; F. G. van der Goot

Membrane insertion of anthrax protective antigen and cytoplasmic delivery of lethal factor occur at different stages of the endocytic pathway

L. Abrami; M. Lindsay; R. Parton; S. Leppla; F. van der Goot

Rafts can trigger contact-mediated secretion of bacterial effectors via a lipid-based mechanism

F. G. van der Goot; G. Tran van Nhieu; A. Allaoui; P. Sansonetti; F. Lafont

Mitogen-activated protein kinase pathways defend against bacterial pore-forming toxins

D. L. Huffman; L. Abrami; R. Sasik; J. Corbeil; F. G. van der Goot  et al.

A bacterial big-MAC attack

I. Iacovache; F. G. van der Goot

Bacterial subversion of lipid rafts

F. Lafont; L. Abrami; F. G. van der Goot

Anthrax toxin triggers endocytosis of its receptor via a lipid raft-mediated clathrin-dependent process

L. Abrami; S. Liu; P. Cosson; S. H. Leppla; F. G. van der Goot

Sensitivity of polarized epithelial cells to the pore-forming toxin aerolysin

L. Abrami; M. Fivaz; P. E. Glauser; N. Sugimoto; C. Zurzolo  et al.

Sliding doors: clathrin-coated pits or caveolae?

M. Felberbaum-Corti; V. D. Goot; F. Gisou; J. Gruenberg

Eukaryotic cells and microbial pathogens: a familiar couple take centre stage

C. R. Roy; F. G. van der Goot

Initial steps of Shigella infection depend on the cholesterol/sphingolipid raft-mediated CD44-IpaB interaction

F. Lafont; G. Tran Van Nhieu; K. Hanada; P. Sansonetti; F. G. van der Goot

Conversion of a transmembrane to a water-soluble protein complex by a single point mutation

Y. Tsitrin; C. J. Morton; C. el-Bez; P. Paumard; M. C. Velluz  et al.

Requirement of N-glycan on GPI-anchored proteins for efficient binding of aerolysin but not Clostridium septicum alpha-toxin

Y. Hong; K. Ohishi; N. Inoue; J. Y. Kang; H. Shime  et al.

The glycan core of GPI-anchored proteins modulates aerolysin binidng but is not sufficient: the polypeptide moiety is required for the toxin-receptor interaction

L. Abrami; M.-C. Velluz; H. Hong; K. Ohishi; A. Mehlert  et al.

Differential sorting and fate of endocytosed GPI-anchored proteins

M. Fivaz; F. Vilbois; S. Thurnheer; C. Pasquali; L. Abrami  et al.

Oiling the wheels of the endocytic pathway

F. G. van der Goot; J. Gruenberg

Association of Helicobacter pylori vacuolating toxin (VacA) with lipid rafts

W. Schraw; Y. Li; M. S. McClain; F. G. van der Goot; T. L. Cover

La vie sans cavéoles

L. Abrami; F. G. van der Goot; F. Lafont

Membranolytic toxins

F. G. van der Goot; M. Fivaz; L. Abrami

Not as simple as just punching a hole

M. Fivaz; L. Abrami; Y. Tsitrin; F. G. van der Goot

Aerolysin from Aeromonas hydrophila and related toxins

M. Fivaz; L. Abrami; Y. Tsitrin; F. G. van der Goot

Cross-talk between caveolae and glycosylphosphatidylinositol-rich domains

L. Abrami; M. Fivaz; T. Kobayashi; T. Kinoshita; R. G. Parton  et al.

Biosystem for epithelial cell culture and electrical characterisation

S. Hediger; A. Sayah; K. Sobo; F. Van der Goot; M. Gijs

The bacterial toxin toolkit

G. Schiavo; F. G. van der Goot

Raft membrane domains: from a liquid-ordered membrane phase to a site of pathogen attack

F. G. van der Goot; T. Harder

Pore-forming toxins

Analysis of glycosyl phosphatidylinositol-anchored proteins by two-dimensional gel electrophoresis

M. Fivaz; F. Vilbois; C. Pasquali; F. G. van der Goot

Plasticity of the transmembrane beta-barrel

F. G. van der Goot

Sensing proteins outside of the box

F. G. van der Goot; S. Matile

Cholesterol-rich plasma membrane microdomains promote oligomerization of the pore.forming toxin aerolysin.

L. Abrami; M. Fivaz; F. G. van der Goot

Adventures of a pore-forming toxin at the target cell surface

L. Abrami; M. Fivaz; F. G. van der Goot

Surface dynamics of aerolysin on the plasma membrane of living cells

L. Abrami; M. Fivaz; F. G. van der Goot

Surface Dynamics of Aerolysin on the Plasma Membrane of Livinf Cells.

L. Abrami; M. Fivaz; F. G. van der Goot

Landing on lipid rafts

M. Fivaz; L. Abrami; F. van der Goot

Plasma membrane microdomains act as concentration platforms to facilitate intoxication by aerolysin

L. Abrami; F. van der Goot

The lectin-like domain of tumor necrosis factor-alpha increases membrane conductance in microvascular endothelial cells and peritoneal macrophages

M. Hribar; A. Bloc; F. G. van der Goot; L. Fransen; P. De Baetselier  et al.

The tip of a molecular syringe

M. Fivaz; F. G. van der Goot

Purification and analysis of authentic CLIP-170 and recombinant fragments

J. Scheel; P. Pierre; J. E. Rickard; G. S. Diamantopoulos; C. Valetti  et al.

The staphylococcal alpha-toxin pore has a flexible conformation

B. Vecsey-Semjen; S. Knapp; R. Möllby; F. van der Goot

Dimer dissociation of the pore-forming toxin aerolysin precedes receptor binding

M. Fivaz; M. C. Velluz; F. G. van der Goot

Increased stability upon heptamerization of the pore-forming toxin aerolysin

C. Lesieur; S. Frutiger; G. Hughes; R. Kellner; F. Pattus  et al.

Membrane interaction of TNF is not sufficient to trigger increase in membrane conductance in mammalian cells

F. G. van der Goot; J. Pugin; M. Hribar; L. Fransen; Y. Dunant  et al.

Pathogens, toxins and lipid rafts

M. Fivaz; L. Abrami; F. van der Goot

A pore-forming toxin interacts with a GPI-anchored protein and causes vacuolation of the endoplasmic reticulum

L. Abrami; M. Fivaz; P. E. Glauser; R. G. Parton; F. G. van der Goot

The pore-forming toxin proaerolysin is activated by furin

L. Abrami; M. Fivaz; E. Decroly; N. G. Seidah; F. Jean  et al.

Brucella abortus transits through the autophagic pathway and replicates in the endoplasmic reticulum of nonprofessional phagocytes

J. Pizarro-Cerda; S. Meresse; R. G. Parton; G. van der Goot; A. Sola-Landa  et al.

Aerolysin induces G-protein activation and Ca2+ release from intracellular stores in human granulocytes

K. H. Krause; M. Fivaz; A. Monod; F. G. van der Goot

Movement of a loop in domain 3 of aerolysin is required for channel formation

J. Rossjohn; S. M. Raja; K. L. Nelson; S. C. Feil; F. G. van der Goot  et al.

Aerolysin--a paradigm for membrane insertion of beta-sheet protein toxins?

J. Rossjohn; S. C. Feil; W. J. McKinstry; D. Tsernoglou; G. van der Goot  et al.

Conformational Changes upon Channel Formation by Staphylococcal alpha-Toxin

B. Vecsey-Semjen; S. Knapp; R. Möllby; F. G. van der Goot

The Pore-Forming Toxin Aerolysin Binds to Microdomains of the Plasma Membrane and Leads to Fragmentation of the Endoplasmic Reticulum.

L. Abrami; M. Fivaz; J. T. Buckley; R. G. Parton; F. G. van der Goot

Separation of early steps in endocytic membrane transport

F. G. van der Goot

The disulfide bond in the Aeromonas hydrophila lipase/acyltransferase stabilizes the structure but is not required for secretion or activity

M. J. Brumlik; F. G. van der Goot; K. R. Wong; J. T. Buckley

Conformational changes due to membrane binding and channel formation by staphylococcal alpha-toxin

B. Vecsey-Semjen; C. Lesieur; R. Mollby; F. G. van der Goot

Conformational changes in aerolysin during the transition from the water-soluble protoxin to the membrane channel

V. Cabiaux; J. T. Buckley; R. Wattiez; J. M. Ruysschaert; M. W. Parker  et al.

Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry in the subunit stoichiometry study of high mass non-covalent complexes

M. Moniatte; C. Lesieur; B. Vecsey-Semjen; J. Buckley; F. Pattus  et al.

Membrane insertion: the strategy of toxins

C. Lesieur; B. Vecsey-Semjn; L. Abrami; M. Fivaz; F. van der Goot

Membrane insertion : the strategy of toxins

C. Lesieur; L. Vecsey-Semjen; L. Abrami; M. Fivaz; F. G. van der Goot

Partial C-terminal unfolding is required for channel formation by staphylococcal alpha-toxin

B. Vecsey-Semjen; R. Mollby; F. G. van der Goot

Characterisation of the heptameric pore-forming complex of the Aeromonas toxin aerolysin using MALDI-TOF mass spectrometry

M. Moniatte; F. G. van der Goot; J. T. Buckley; F. Pattus; A. van Dorsselaer

Aerolysin--the ins and outs of a model channel-forming toxin

M. W. Parker; F. G. van der Goot; J. T. Buckley

Membrane insertion of toxins

C. Lesieur; B. Vecsey-Semjen; M. Kruse; F. G. van der Goot

Structure and Assembly of the Channel-Forming Aeromonas Toxin Aerolysin

M. W. Parker; J. T. Buckley; F. van der Goot; D. Tsernoglou

Protonation of histidine-132 promotes oligomerization of the channel-forming toxin aerolysin

J. T. Buckley; H. U. Wilmsen; C. Lesieur; A. Schulze; F. Pattus  et al.

The C-terminal peptide produced upon proteolytic activation of the cytolytic toxin aerolysin is not involved in channel formation.

F. van der Goot; K. Hardie; M. Parker; J. Buckley

The pore-forming toxin aerolysin: from the soluble form to the transmembrane channel

F. van der Goot; F. Pattus; J. Buckley

The cytolytic toxin aerolysin: from the soluble form to the transmembrane channel

F. G. van der Goot; F. Pattus; M. Parker; J. T. Buckley

All in the family: the toxic activity of pore-forming colicins

J. Lakey; F. G. van der Goot; F. Pattus

The cytolytic aerolysin : how a Janus protein turns inside-out upon membrane insertion and pore formation ?

F. G. van der Goot; F. Pattus; H. U. Wilmsen; R. MacDonald; K. Leonard  et al.

Oligomerization of the channel-forming toxin aerolysin precedes insertion into lipid bilayers

F. G. van der Goot; F. Pattus; K. R. Wong; J. T. Buckley

Dimerization stabilizes the pore-forming toxin aerolysin in solution.

F. van der Goot; J. Ausio; K. Wong; F. Pattus; J. Buckley

Modèle d'étude de l'insertion des protéines membranaires

F. van der Goot; F. Pattus

Role of acidic lipids in the translocation and channel activity of colicins A and N in Escherichia coli cells

F. G. van der Goot; N. Didat; F. Pattus; W. Dowhan; L. Letellier

Physical and chemical characterization of the oligomerization state of the Aeromonas hydrophila lipase/acyltransferase

J. Ausio; F. G. van der Goot; J. T. Buckley

Modèles d'études de l'insertion des protéines membranaires

F. G. van der Goot; F. Pattus

Spectroscopic study of the activation and oligomerization of the channel-forming toxin aerolysin: identification of the site of proteolytic activation

F. G. van der Goot; J. Lakey; F. Pattus; C. M. Kay; O. Sorokine  et al.

Flow cytometry and sorting of amphibian bladder endocytic vesicles containing ADH-sensitive water channels

F. G. van der Goot; A. Seigneur; J. C. Gaucher; P. Ripoche

Primary and secondary structure of the pore-forming peptide of pathogenic Entamoeba histolytica

M. Leippe; E. Tannich; R. Nickel; G. van der Goot; F. Pattus  et al.

The molten globule intermediate for protein insertion or translocation through membranes

F. G. van der Goot; J. H. Lakey; F. Pattus

The membrane insertion of colicins

J. H. Lakey; J. M. González-Mañas; F. G. van der Goot; F. Pattus

Mechanism of water transport accross the renal proximal tubule.

B. Corman; F. G. van der Goot

Puncturing cell membranes : comparison of colicin A and Aerolysin

N. Didat; J.-M. Gonzales-Manas; F. G. van der Goot; D. Jeanteur; F. Lakey  et al.

Evidence for permanent water channels in the basolateral membrane of an ADH-sensitive epithelium

F. van der Goot; B. Corman; P. Ripoche

Axial heterogeneity of apical water permeability along rabbit kidney proximal tubule

F. Van Der Goot; B. Corman

A 'molten-globule' membrane-insertion intermediate of the pore-forming domain of colicin A

F. G. van der Goot; J. M. Gonzalez-Manas; J. H. Lakey; F. Pattus

Water permeabilities and salt reflection coefficients of luminal, basolateral and intracellular membrane vesicles isolated from rabbit kidney proximal tubule

F. G. van der Goot; R. A. Podevin; B. J. Corman

Determination of solute reflection coefficients in kidney brush-border membrane vesicles by light scattering: influence of the refractive index

F. van der Goot; P. Ripoche; B. Corman