Jérôme Waser
EPFL SB ISIC LCSO
BCH 1402 (Batochime UNIL)
Av. F.-A. Forel 2
1015 Lausanne
Web site: Web site: https://lcso.epfl.ch
Web site: Web site: https://www.epfl.ch/schools/sb/scgc/
+41 21 693 93 88
Office:
BCH 4306
EPFL
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VPA-AVP-DLE
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AVP-DLE-EDOC
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EDCH-ENS
Mission
To learn more about our mission, please have a look at the LCSO website: http://lcso.epfl.ch/Biography
Jérôme Waser biography and CV: https://www.epfl.ch/labs/lcso/waser/Publications
Infoscience publications
Infoscience
Silyl Ethynyl Benziodoxolone Reagents
Encyclopedia of Reagents for Organic Synthesis; Wiley, 2012.Iron-Catalyzed [3+2] Annulation of Aminocyclopropanes with Aldehydes: Stereoselective Synthesis of Aminotetrahydrofurans
Organic Letters. 2012. DOI : 10.1021/ol203144v.Indole Alkaloids Synthesis via a Selective Cyclization of Aminocyclopropanes
CHIMIA. 2012. DOI : 10.2533/chimia.2012.233.Catalytic Formal Homo-Nazarov Reaction and Other Cyclizations of Cyclopropanes : from Methodology to Total Synthesis
Lausanne, EPFL, 2012. DOI : 10.5075/epfl-thesis-5269.Catalytic Enantiospecific [3+2] Annulation of Aminocyclopropanes with Ketones
Chemistry - A European Journal. 2012. DOI : 10.1002/chem.201103971.Para-Selective Gold-Catalyzed Direct Alkynylation of Anilines
Organic Letters. 2012. DOI : 10.1021/ol203289v.Electrophilic alkynylation: the dark side of acetylene chemistry
Chemical Society Reviews. 2012. DOI : 10.1039/c2cs35034c.Ethynyl Benziodoxolones for the Direct Alkynylation of Heterocycles: Structural Requirement, Improved Procedure for Pyrroles, and Insights into the Mechanism
Chemistry - A European Journal. 2012. DOI : 10.1002/chem.201200200.Asymmetric Organocatalysis Meets Hypervalent Iodine Chemistry for the alpha-Functionalization of Carbonyl Compounds
Chemcatchem. 2012. DOI : 10.1002/cctc.201200116.Synthesis of 1-[(Triisopropylsilyl)ethynyl]-1 lambda(3),2-benziodoxol-3(1H)-one and Alkynylation of Indoles, Thiophenes, and Anilines
Synthesis-Stuttgart. 2012. DOI : 10.1055/s-0031-1290589.Development of Catalytic Umpolung : Part 1: Direct Alkynylation of Heterocycles and Electron-Rich Aromatics using Alkynyl-Benziodoxolones - Part 2: Synthesis of New Bifunctional (Thio)urea-Carbene Catalysts
Lausanne, EPFL, 2012. DOI : 10.5075/epfl-thesis-5397.Benziodoxole-based hypervalent iodine reagents for atom-transfer reactions
Chemical Communications (ChemComm). 2011. DOI : 10.1039/c0cc02265a.Formal Homo-Nazarov and Other Cyclization Reactions of Activated Cyclopropanes
Chemistry - A European Journal. 2011. DOI : 10.1002/chem.201102583.Catalytic [3+2] Annulation of Aminocyclopropanes for the Enantiospecific Synthesis of Cyclopentylamines
Angewandte Chemie International Edition. 2011. DOI : 10.1002/anie.201106255.Cyclopropanes and Hypervalent Iodine Reagents: High Energy Compounds for Applications in Synthesis and Catalysis
CHIMIA. 2011. DOI : 10.2533/chimia.2011.649.Benziodoxole-based hypervalent iodine reagents for atom-transfer reactions
Chemical Communications (ChemComm). 2011. DOI : 10.1039/C0CC02265A.A Palladium-Catalyzed Aminoalkynylation Strategy towards Bicyclic Heterocycles: Synthesis of (±)-Trachelanthamidine
Angewandte Chemie International Edition. 2011. DOI : 10.1002/anie.201100718.New Acetylene Chemistry : Direct [alpha]-Alkynylation of Carbonyls with Ethynyl Benziodoxolones (EBX)
Lausanne, EPFL, 2011. DOI : 10.5075/epfl-thesis-5214.One-pot gold-catalyzed synthesis of 3-silylethynyl indoles from unprotected o-alkynylanilines
Beilstein Journal Of Organic Chemistry. 2011. DOI : 10.3762/bjoc.7.65.Pd(0)-Catalyzed Oxy- and Aminoalkynylation of Olefins for the Synthesis of Tetrahydrofurans and Pyrrolidines
Organic Letters. 2011. DOI : 10.1021/ol2029383.Cyclization of Aminocyclopropanes in Indole Alkaloids Synthesis
Synlett. 2011. DOI : 10.1055/s-0030-1259553.Ethynyl-1,2-benziodoxol-3(1 H)-one (EBX): An Exceptional Reagent for the Ethynylation of Keto, Cyano, and Nitro Esters
Chemistry - A European Journal. 2010. DOI : 10.1002/chem.201001539.Synthesis of Chiral Bifunctional (Thio)Urea N-Heterocyclic Carbenes
Synlett. 2010. DOI : 10.1055/s-0029-1219543.Catalytic Selective Cyclizations of Aminocyclopropanes: Formal Synthesis of Aspidospermidine and Total Synthesis of Goniomitine
Angewandte Chemie International Edition. 2010. DOI : 10.1002/anie.201001853.Pd-Catalyzed Intramolecular Oxyalkynylation of Alkenes with Hypervalent Iodine
Organic Letters. 2010. DOI : 10.1021/ol9027286.Azides by Olefin Hydroazidation Reactions
Organic Azides: Syntheses and Applications; Wiley, 2010. p. 95 - 112.Direct Alkynylation of Thiophenes: Cooperative Activation of TIPS–EBX with Gold and Brønsted Acids
Angewandte Chemie International Edition. 2010. DOI : 10.1002/anie.201003179.Cyclization of Cyclopropyl Carbonyls and the Homo-Nazarov Reaction
CHIMIA. 2009. DOI : 10.2533/chimia.2009.162.Catalytic Formal Homo-Nazarov Cyclization
Organic Letters. 2009. DOI : 10.1021/ol802970g.Direct Alkynylation of Indole and Pyrrole Heterocycles
Angewandte Chemie International Edition. 2009. DOI : 10.1002/anie.200905419.Cyclization and Cycloaddition Reactions of Cyclopropyl Carbonyls and Imines
Synthesis. 2009. DOI : 10.1055/s-0029-1216998.Other publications
Full publication list
A full publication list of LCSO with graphical abstracts is available on the following website: http://lcso.epfl.ch/PublicationsResearch
Link to our resarch
A regularly updated description of our research program is available on the following website: http://lcso.epfl.ch/ResearchTeaching & PhD
Teaching
Chemistry and Chemical Engineering
PhD Students
Aregger Nina, Baldassari Carlo, Kamei Yuji, Lee Najung, Marty Christine Alice Jacqueline, Nguyen Vu Trung Tin, Olikauskas Valentas, Robert Emma Gabrielle Louise, Schöpfer Alexandre Alain, Solé Àvila Helena, Tanguy Clément Gabriel Baptiste, Wu Wei,Past EPFL PhD Students
Amos Stephanie Grace Elizabeth , Borrel Julien Aymeric , Brand Jonathan , Caramenti Paola , Cavalli Diana , Das Ashis Kumar , De Simone Filippo , De la Barre De Nanteuil Florian Patrick Marie Daniel , Declas Nina , Fernández González Davinia , Garreau Marion Marie-Agnès , Greenwood Phillip Gulliver Dominic , Grinhagena Elija , Le Du Eliott Hugo Joran , Le Vaillant Franck , Li Yifan , Liu Xingyu , Muriel Bastian Antoine Rodolphe Claude , Nicolai Stefano , Orcel Ugo Jonathan , Palamini Pierre Gérard Joseph , Perrotta Daniele , Pisella Guillaume Dominique , Purins Mikus , Racine Sophie Lucie , Simonet-Davin Raphaël Michel Henri , Smyrnov Vladyslav , Tessier Romain Gaëtan , Vita Maria Victoria , Wang Mingming ,Courses
Advanced general chemistry I
This course comprises of two parts. The bases of the thermodynamics of equilibria and of the kinetics of reactions are introduced. The first notions of quantum chemistry on electrons and bonds, exemplified in organic chemistry, are presented in the second part.
Advanced general chemistry II
Fundamental knowledge on the reactivity of organic compounds and their identification by mass spectrometry, IR spectroscopy and nuclear magnetic resonance.
Sustainable chemistry and engineering in Industry
In the course given by experts from the Swiss Chemical industry, the students will be introduced in key concepts of sustainable chemistry and chemical engineering of industrial relevance. They will be able to learn from real hands-on problems and to better understand the challenges faced in industry
Frontiers in Sustainable Chemical Synthesis
The students will become familiar with the most recent progress in sustainable synthetic chemistry, covering a broad rang of topics such as catalysis, heterocyclic chemistry, stereoselective synthesis and new synthetic tools.