Francesco Stellacci

Edit profile

Full Professor

francesco.stellacci@epfl.ch +41 21 693 78 72 http://sunmil.epfl.ch/

https://orcid.org/0000-0003-4635-6080

Scopus ID

Google Scholar ID

EPFL STI IMX SUNMIL
MXG 030 (Bâtiment MXG)
Station 12
1015 Lausanne

+41 21 693 78 72
+41 21 693 73 96
Office: MXG 030
EPFL > STI > IMX > SUNMIL

Web site: Web site: https://sunmil.epfl.ch

EPFL STI IBI-GE
AAB
Station 15
1015 Lausanne

+41 21 693 78 72
EPFL > STI > IBI-STI > IBI-STI-GE

Web site: Web site: https://bioengineering.epfl.ch/

+41 21 693 78 72
EPFL > VPA > VPA-FAC > ASC

+41 21 693 78 72
EPFL > VPA > VPA-FAC > CPR

vCard
Administrative data

Fields of expertise

Nanomaterials,
Nanoparticles,
Soft Materials,
Supramolecular interactions,
Solid-Liquid Interfaces,
Nanomedicine
Antivirals

Mission

Prof. Stellacci heads the Supramolecular NanoMaterials and Interfaces Laboratory (SuNMiL).
SuNMIL mission is to uncover the complex interactions that take place between supramolecular assemblies and the molecular world that surrounds them. To achieve this goal novel materials are synthesizes and characterized. A special attention is devoted to the creation, characterization, and understanding of supramolecular interfaces that present nanoscale domains.

Representative papers are:

1. Jackson, A. M.; Myerson, J. W.; Stellacci, F. Spontaneous assembly of sub-nanometre ordered domains in the ligand shell of monolayer protected nanoparticles Nature Materials, 3, 330-336, 2004
2. Halik, M.; Klauk, H.; Zschieschang, U.; Schmid, G.; Dehm, C.; Schütz, M.; Maisch, S.; Effenberger, F.; Brunnbauer, M.; Stellacci, F. Low-voltage organic transistors with an amorphous molecular gate dielectric Nature, 431, 963-966, 2004
3. AYu, A. A.; Savas, T. A.; Taylor G. S.; Guiseppe-Elie A.; Smith H. I.; Stellacci F. Supramolecular Nano-stamping: using DNA as movable type, Nano Letters, 5, 1061-1066, 2005
4. DeVries, G. A.; Brunnbauer, M.; Hu, Y.; Jackson, A. M.; Long, B.; Neltner, B.; Uzun, O.; Wunsch, B. H.; Stellacci, F. Divalent Metal Nanoparticles: From One-Dimensional Chains to Self-Standing Films, Science, 315, 358-361, 2007
5. Singh, C; Ghorai, P. K.; Horsch, M. A.; Jackson, A. M.; Larson, R. G.; Stellacci, F.; Glotzer, S.C. Entropy-Mediated Patterning of Surfactant-Coated Nanoparticles and Surfaces Physical Review Letters, 99, 226106 (1-4), 2007
6. Verma, A.; Uzun, O.; Hu, Y.; Han, H.-S.; Watson N.; Chen S.; Irvine, D. J.; Stellacci, F. Surface Structure-Regulated Cell Membrane Penetration by Monolayer Protected Nanoparticles, Nature Materials, 7, 588-595, 2008
7. Yuan, J.; Liu, X.; Akbulut, O.; Hu, J.; Suib, S. L.; Kong J.; Stellacci, F. Selective Superwetting Nanowire Membranes, Nature Nanotechnology, 3, 332-336, 2008
8. Centrone, A.; Penzo, E.; Sharma, M.; Myerson, J. W.; Jackson A. M.; Marzari, N.; Stellacci, F. The role of nanostructure in the wetting behavior of mixed-monolayer-protected metal nanoparticles, Proceeding of the National Academy of Science, 105, 9886-9891, 2008
9. Kuna, J.J., Voitchovsky, K., Singh, C.; Jiang, H.; Mwenifumbo, S.; Ghorai, P.K.; Stevens, M.M., Glotzer, S.C.; Stellacci, F. The Effect of Nanometre-Scale Structure on Interfacial Energy, Nature Materials, 10, 837-842, 2009
10. Voïtchovsky, K.; Kuna, J.J.; Antoranz Contera, S.; Tosatti, E.; Stellacci F. Direct mapping of the solid-liquid adhesion energy with sub-nanometer resolution, Nature Nanotech., 5, 401-405, 2010

Biography

Francesco Stellacci graduated in Materials Engineering at the Politecnico di Milano in 1998 with a thesis on photochromic polymers with Prof. Giuseppe Zerbi and Mariacarla Gallazzi. In 1999 he moved to the Chemistry Department of the University of Arizona for as a post-doc in the group of Joe Perry in close collaboration with the group of Seth Marder. In 2002 he moved to the Department of Materials Science and Engineering at the Massachusetts Institute of Technology as an assistant professor. He was then promoted to associate without (2006) and with tenure (2009). In 2010 he moved to the Institute of Materials at EPFL as a full Professor. He holds the Alcan EP Chair. Francesco was one of the recipients of the Technology Review TR35 "35 Innovator under 35" award in 2005, and the Popular Science Magazine "Brilliant 10" award in 2007. He has been a Packard Fellow starting 2005.

Publications

Infoscience publications

Publications

Structure-Activity Relationship Studies of Glycosaminoglycan Mimetic Macrocycles Against Herpes

S. Pawar; H. T. Tran; M. Ozkan; D. Sardana; C. P. Aigroz et al.

CHEMISTRY OF MATERIALS. 2025. DOI : 10.1021/acs.chemmater.4c02016.

Francesco Stellacci

Full Professor

Fields of expertise

Mission

Biography

Publications

Infoscience publications

Publications

Structure-Activity Relationship Studies of Glycosaminoglycan Mimetic Macrocycles Against Herpes

Physical determinants of nanoparticle-mediated lipid membrane fusion

Robot-Assisted Measurement of the Critical Micelle Concentration

Long-Term Protein Synthesis with PURE in a Mesoscale Dialysis System

Reliable and robust robotic handling of microplates via computer vision and touch feedback

Cholesterol-rich lipoprotein nanoparticles for cancer diagnosis

Proteins as sustainable and recyclable polymers for a circular economy in bioplastics

Size distributions and fractograms of cholesterol-rich lipoprotein nanoparticles for cancer diagnosis

Structure-Property Relationships of Elastomeric Vinylogous Urethane Thermosets and Their Application as Closed-Loop Recyclable Strain Sensors

Amino acids modulate liquid-liquid phase separation in vitro and in vivo by regulating protein-protein interactions

Direct Monomer Recovery from Ring-Closing Depolymerization of Thermosets

Development of Broad-Spectrum β-Cyclodextrins-Based Nanomaterials Against Influenza Viruses

Combining external physical stimuli and nanostructured materials for upregulating pro-regenerative cellular pathways in peripheral nerve repair

Inhibition of influenza virus infection in mice by pulmonary administration of a spray dried antiviral drug

Reaction of β-Ketoester and 1,3-Diol to Access Chemically Recyclable and Mechanically Robust Poly(vinyl alcohol) Thermosets through Incorporation of β-(1,3-dioxane)ester

Modulating Weak Protein-Protein Cross-Interactions by the Addition of Free Amino Acids at Millimolar Concentrations

Nature-inspired recycling of a protein mixture into a green fluorescent protein-based hydrogel

Amino Acids and Their Biological Derivatives Modulate Protein-Protein Interactions in an Additive Way

Broad-Spectrum Supramolecularly Reloadable Antimicrobial Coatings

Benzene with Alkyl Chains Is a Universal Scaffold for Multivalent Virucidal Antivirals

A Synthetic Multivalent Lipopeptide Derived from Pam3CSK4 with Irreversible Influenza Inhibition and Immuno-Stimulating Effects

Beyond the limiting gap length: peripheral nerve regeneration through implantable nerve guidance conduits

Versatile Capillary Cells for Handling Concentrated Samples in Analytical Ultracentrifugation

Engineering nanomaterial surfaces for biomedical applications: antiviral surface coatings, antiviral nanoparticles and lipid-based biopharmaceutical drug systems

Materials science experiments by robotic automation

Two-component paint, antimicrobial surface and preparation method thereof

Supramolecular Architectures of Dendritic Polymers Provide Irreversible Inhibitor to Block Viral Infection

Hydrophobic Interaction and its Small Molecule effect

Peptide-based virucidal drugs

Virucidal compounds and use thereof

Ligand concentration determines antiviral efficacy of silica multivalent nanoparticles

Editorial to the special issue on the 35th EFFoST international conference in future foods 'Future Food for Healthy Individuals, Resilient Communities, and Global Food Security'

Difference in astringency of the main pea protein fractions

Simultaneous Electrophysiology and Imaging Reveal Changes in Lipid Membrane Thickness and Tension upon Uptake of Amphiphilic Gold Nanoparticles

Amphiphilic Au nanoparticles and cholesterol-containing liposomes serving as minimal tunable fusion machinery

Influence of structural dynamics on cell uptake investigated with single-chain polymeric nanoparticles

Reversible Microscale Assembly of Nanoparticles Driven by the Phase Transition of a Thermotropic Liquid Crystal

Development of an inhalable antiviral powder formulation against respiratory syncytial virus

Editorial to the special issue on the 35(th) EFFoST International Conference in Innovative Food Science and Emerging Technologies

Recycling of Polymerase Chain Reaction (PCR) Kits

Cholesterol-Containing Liposomes Decorated With Au Nanoparticles as Minimal Tunable Fusion Machinery

Antiviral Mechanism of Virucidal Sialic Acid Modified Cyclodextrin

Virucidal compositions and use thereof

Multivalent Virucidal Antivirals: Synthesis, Mechanisms of Action, and Immune-stimulating Effects

Stress granules quantification on fixed and live cells

Antiviral compounds, compositions and uses thereof

Photodynamic treatment of multidrug-resistant bacterial infection using indium phosphide quantum dots

Peptide-Grafted Nontoxic Cyclodextrins and Nanoparticles against Bacteriophage Infections

Lignin: A Sustainable Antiviral Coating Material

Monovalent ion-mediated charge-charge interactions drive aggregation of surface-functionalized gold nanoparticles

An anti-influenza combined therapy assessed by single cell RNA-sequencing

Quantifying the Solution Structure of Metal Nanoclusters Using Small-Angle Neutron Scattering

Site-selective surface enhanced Raman scattering study of ligand exchange reactions on aggregated Ag nanocubes

Experimental Method to Distinguish between a Solution and a Suspension

Potent Virustatic Polymer-Lipid Nanomimics Block Viral Entry and Inhibit Malaria Parasites In Vivo

Ion-bridges and lipids drive aggregation of same-charge nanoparticles on lipid membranes

Site-selective overgrowth of Ag nanocrystals by Polyvinylpyrrolidone-mediated atom deposition by Ostwald ripening

DNA as a Recyclable Natural Polymer

Polyanionic Amphiphilic Dendritic Polyglycerols as Broad-Spectrum Viral Inhibitors with a Virucidal Mechanism

Protein Engineering for Personalized therapy and diagnosis

Cryogenic electron tomography to determine thermodynamic quantities for nanoparticle dispersions

Sulfated and sulfonated dendritic polyglycerols and use thereof as broad-spectrum virucidal agents

Single-Chain Nanoparticles for Intracellular Drug Delivery

Control and Characterization of the Compactness of Single-Chain Nanoparticles

In-situ Investigations on Gold Nanoparticles Stabilization Mechanisms in Biological Environments Containing HSA

Broad-spectrum nanoparticles against bacteriophage infections

Amphiphilic nanoparticles generate curvature in lipid membranes and shape liposome-liposome interfaces

Nanoparticle-Induced Disorder at Complex Liquid-Liquid Interfaces: Effects of Curvature and Compositional Synergy on Functional Surfaces

Nature-Inspired Circular-Economy Recycling for Proteins: Proof of Concept

Cholesterol Hinders the Passive Uptake of Amphiphilic Nanoparticles into Fluid Lipid Membranes

An antiviral trap made of protein nanofibrils and iron oxyhydroxide nanoparticles

Interferon Lambda Delays the Emergence of Influenza Virus Resistance to Oseltamivir