Bruno Correia
Nationalité: Portuguese
+41 21 693 61 66
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+41 21 693 61 66
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Publications représentatives
De novo protein design enables precise induction of functional antibodies in vivo
Sesterhenn F*, Yang C*, Cramer JT, Bonet J, Wen X, Abriata LA, Kucharska I, Chiang CI, Wang Y, Castoro G, Vollers SS, Galloux M, Dheilly E, Richard CA, Rosset S, Corthesy P, Georgeon S, Villard M, Richard CA, Descamps D, Delgado T, Oricchio E, Rameix-Welti MA, Mas V, Ervin S, Eleouet JF, Riffault S, Bates JT, Julien JP, Li Y, Jardetzky T, Krey T, Correia BE
Published in Science, 2020 in
Computational design of anti-CRISPR proteins with improved inhibition potency and expanded specificity
Mathony J*, Harteveld Z*, Schmelas C*, Belzen JU, Aschenbrenner S, Hoffmann MD, Stengl C, Scheck A, Rosset S, Grimm D, Eils R, Correia BE*, Niopek D*
Published in Nature Chemical Biology, 2020 in
Macromolecular modeling and design in Rosetta: recent methods and frameworks
Leman JK, Weitzner BD, Lewis SM, Adolf-Bryfogle J, Alam N, Alford RF, Aprahamian M, Baker D, Barlow KA, Barth P, Basanta B, Bender BJ, Blacklock K, Bonet J, Boyken SE, Bradley P, Bystroff C, Conway P, Cooper S, Correia BE, Coventry B, Das R, De Jong RM, DiMaio F, Dsilva L, Dunbrack R, Ford AS, Frenz B, Fu DY, Geniesse C, Goldschmidt L, Gowthaman R, Gray JJ, Gront D, Guffy S, Horowitz S, Huang PS, Huber T, Jacobs TM, Jeliazkov JR, Johnson DK, Kappel K, Karanicolas J, Khakzad H, Khar KR, Khare SD, Khatib F, Khramushin A, King IC, Kleffner R, Koepnick B, Kortemme T, Kuenze G, Kuhlman B, Kuroda D, Labonte JW, Lai JK, Lapidoth G, Leaver-Fay A, Lindert S, Linsky T, London N, Lubin JH, Lyskov S, Maguire J, Malmström L, Marcos E, Marcu O, Marze NA, Meiler J, Moretti R, Mulligan VK, Nerli S, Norn C, Ó'Conchúir S, Ollikainen N, Ovchinnikov S, Pacella MS, Pan X, Park H, Pavlovicz RE, Pethe M, Pierce BG, Pilla KB, Raveh B, Renfrew PD, Burman SSR, Rubenstein A, Sauer MF, Scheck A, Schief W, Schueler-Furman O, Sedan Y, Sevy AM, Sgourakis NG, Shi L, Siegel JB, Silva DA, Smith S, Song Y, Stein A, Szegedy M, Teets FD, Thyme SB, Wang RY, Watkins A, Zimmerman L, Bonneau R
Published in Nature Methods, 2020 in
Computationally designed STOP-CAR disrupted by small molecule confers on-command regulation of T-cell therapy
Giordano-Attianese G*, Gainza P*, Gray-Gaillard E*, Cribioli E, Shui S, Kim S, Kwak M, Vollers S, Osorio A, Reichenbach P, Bonet J, Oh B, Irving M*, Coukos G*, Correia BE*
Published in Nature Biotechnology, 2020 in
Deciphering interaction fingerprints from protein molecular surfaces using geometric deep learning
Gainza P, Sverrisson F, Monti F, Rodola E, Bronstein MM, Correia BE
Published in Nature Methods, 2020 in
rstoolbox - a Python library for large-scale analysis of computational protein design data and structural bioinformatics
Bonet J, Harteveld Z, Sesterhenn F, Scheck A, Correia BE
Published in BMC Bioinformatics, 2019 in
Boosting subdominant neutralizing antibody responses with a computationally designed epitope-focused immunogen
Sesterhenn F, Galloux M, Vollers S, Cspregi L, Yang C, Descamps D, Bonet J, Friedensohn S, Gainza P, Corthesy P, Chen M, Rosset S, Rameix-Welti MA, Elouet JF, Reddy ST, Graham B, Riffault S, Correia BE
Published in Plos Biology, 2019 in
Rosetta FunFolDes - a general framework for the computational design of functional proteins
Bonet J*, Wehrle S*, Schriever K*, Yang C*, Billet A, Sesterhenn F, Scheck A, Sverrisson F, Veselkova B, Vollers S, Lourman R, Villard M, Rosset S, Krey T, Correia BE
Published in Plos Computational Biology, 2018 in
Engineered anti-CRISPR proteins for optogenetic control of CRISPR/Cas9
Bubeck F, Hoffmann M, Harteveld Z, Aschenbrenner S, Bietz A, Waldhauer MC, Boerner K, Fakhiri J, Schmelas C, Dietz L, Grimm D, Correia BE, Eils R, Niopek D
Published in Nature Methods, 2018 in
Enseignement et PhD
Doctorant·es actuel·les
Shuhao Xiao, Irina Morozova, Yangyang Miao, Pengkang Guo, Mubarak Olanrewaju Idris, Adrian Wolfgang Dobbelstein, Julius Wenckstern, Flávia Mayumi Odahara de Abreu, Marin Paul Geoffroy Marie Ollagnon, Evgenia Elizarova, Christian Schellhaas, Tian Zhu, Ekaterina Pyatova, Lennart Nickel, Petra Elisabeth Marilena Balbi, Nicolas Manuel Goldbach, Rebecca Manuela Neeser, Helen Schmid
A dirigé les thèses EPFL de
Fabian Sesterhenn (2019), Che Yang (2020), Andreas Scheck (2021), Zander Harteveld (2022), Sailan Shui (2022), Sarah Wehrle (2022), Alexandra Krina Van Hall-Beauvais (2023), Anthony Marchand (2024), Freyr Sverrisson (2024), Karla Montserrat Castro Gilabert (2024), Ahmed Sadek (2025), Casper Goverde (2025), Stephen Michael Buckley (2025), Ilia Igashov (2026), Arne Schneuing (2026), Maddalena Elia (2026)
A co-dirigé les thèses EPFL de
Mathieu Girardin (2023), Lucia Bonati (2025)
Cours
Bio-organic chemistry
BIO-110
L'objectif du cours est de fournir une compréhension chimique et une intuition pour déchiffrer et prédire les processus chimiques dans les systèmes vivants.
BioEngineering Student Seminar Series
BIOENG-613
Monthly IBI-EDBB Mini-symposia
BIOENG-600