Albert Santamaria Martinez

Nationality: Swiss

EPFL SV ISREC UPORICCHIO
SV 2824 (Bâtiment SV)
Station 19
CH-1015 Lausanne

Expertise

Personalized medicine, tumor microenvironment, cancer stem cells.

Current work

TUMORSHARE | Personalized medicine, tumor microenvironment, therapy resistance, biobanking.

Awards

Pfizer Prize in Oncology

2013

SNF Ambizione

PZ00P3_154751, Principal Investigator

2015

Anna Fuller Fund Grant

2011

Vall d' Hebron Research Institute Foundation Grant

2005

Krebsliga grant

KLS-4121-02-2017, Principal Investigator

2017

Fondazione San Salvatore

Co-Principal Investigator

2021

Selected publications

Development of patient-derived lymphomoids with preserved tumor architecture for lymphoma therapy screening

Albert Santamaria- Martínez✉︎, Justine Epiney, Divyanshu Srivastava, Daniele Tavernari, Marco Varrone, Dina Milowich, Igor Letovanec, Thorsten Krueger, Rafael Duran, Giovanni Ciriello, Anne Cairoli & Elisa Oricchio✉︎
Published in Nature Communications volume 15, 10650 (2024) in

Metabolic dependencies of metastasis-initiating cells in female breast cancer

C. Megan Young, Laurent Beziaud, Pierre Dessen, Angela Madurga Alonso, Albert Santamaria-Martínez✉︎ & Joerg Huelsken✉︎
Published in Nature Communications volume 14, 7076 (2023) in

The Tumor Microenvironment as a Driving Force of Breast Cancer Stem Cell Plasticity

Flavia Fico & Albert Santamaria-Martínez✉︎
Published in Cancers (Basel) . 2020 Dec 21;12(12):3863. in

TGFBI modulates tumour hypoxia and promotes breast cancer metastasis

Flavia Fico & Albert Santamaria-Martínez✉︎
Published in Molecular oncology, Vol. 14, Issue 12, 2020 in

Breast cancer stem cells with tumor vs metastasis initiating capacities are modulated by TGFBR1 inhibition

Flavia Fico, Mélanie Bousquenaud, Curzio Rüegg and Albert Santamaria-Martínez✉︎
Published in Stem Cell Reports 2019, Vol. 13, 1-9 in

Obesity promotes the expansion of metastasis-initiating cells

Mélanie Bousquenaud, Flavia Fico, Giovanni Solinas, Curzio Rüegg* and Albert Santamaria- Martínez✉︎*
Published in Breast Cancer Research, 2018, 20:104 in

The niche under siege: novel targets for metastasis therapy

Santamaria-Martínez A. and Huelsken J.
Published in Journal of Internal Medicine 2013, 274(2):127-36 in

Interactions between cancer stem cells and their niche govern metastatic colonization

Ilaria Malanchi*, Albert Santamaria-Martínez*, Evelyn Susanto, Hong Peng, Hans-Anton Lehr, Jean-Francois Delaloye & Joerg Huelsken
Published in Nature 481, 85:89, 2012 (*equal contribution) in

Research

Book chapters

Dafflon C., Santamaria-Martínez A., and Ordóñez-Morán P.: An Intrasplenic Injection Model for the Study of Cancer Stem Cells Seeding Capacity. Intestinal Stem Cells: Methods and Protocols, ed. P. Ordóñez-Morán, Springer. 2020.
Huelsken J. and Santamaria-Martínez A.: Cancer stem cells in metastasis and minimal residual disease. Cancer Stem Cells, ed. V.K. Rajasekhar, Wiley Press, 2014.