Domaines de compétences
Spectroscopie 1H, 13C, 15N dynamique in vivo
Tomographie par émission de positrons
Modèles mathématiques de métabolisme
PET CMRglc mapping and H-1-MRS show altered glucose uptake and neurometabolic profiles in BDL ratsAnalytical Biochemistry. 2022-06-15. DOI : 10.1016/j.ab.2022.114606.
Quantitative FDG-PET and 1H-MRS reveal altered glucose uptake and neurometabolic profiles in BDL rats2022-06-01. p. 57-58.
Excitatory/inhibitory neuronal metabolic balance in mouse hippocampus upon infusion of [U-C-13(6)]glucoseJournal Of Cerebral Blood Flow And Metabolism. 2021. DOI : 10.1177/0271678X20910535.
Magnetic resonance spectroscopy in the rodent brain: Experts' consensus recommendationsNmr In Biomedicine. 2020-08-26. DOI : 10.1002/nbm.4325.
Terminology and concepts for the characterization of in vivo MR spectroscopy methods and MR spectra: Background and experts' consensus recommendationsNmr In Biomedicine. 2020-08-17. DOI : 10.1002/nbm.4347.
Neuronal energy metabolism in the mouse brain measured by H-1-[C-13] MRS at 14.1T under [3-C-13]-Lactate infusion: a feasibility study2019-07-01. 29th International Symposium on Cerebral Blood Flow, Metabolism and Function / 14th International Conference on Quantification of Brain Function with PET (BRAIN and BRAIN Pet), Yokohama, JAPAN, Jul 04-07, 2019. p. 208-209.
Hyperpolarized C-13 Magnetic Resonance Spectroscopy Reveals the Rate-Limiting Role of the Blood-Brain Barrier in the Cerebral Uptake and Metabolism of L-Lactate in VivoAcs Chemical Neuroscience. 2018-11-01. DOI : 10.1021/acschemneuro.8b00066.
In vivo (13)C MRS in the mouse brain at 14.1 Tesla and metabolic flux quantification under infusion of [1,6-(13)C2]glucoseJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 2018. DOI : 10.1177/0271678X17734101.
MRS studies of neuroenergetics and glutamate/glutamine exchange in rats: Extensions to hyperammonemic modelsAnalytical biochemistry. 2017. DOI : 10.1016/j.ab.2016.11.021.
New technologies – new insights into the pathogenesis of hepatic encephalopathyMetabolic Brain Disease. 2016. DOI : 10.1007/s11011-016-9906-y.
(1)H and (31)P magnetic resonance spectroscopy in a rat model of chronic hepatic encephalopathy: in vivo longitudinal measurements of brain energy metabolismMetabolic brain disease. 2016. DOI : 10.1007/s11011-015-9715-8.
Assessment of metabolic fluxes in the mouse brain in vivo using (1)H-[(13)C] NMR spectroscopy at 14.1 TeslaJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 2015. DOI : 10.1038/jcbfm.2014.251.
Neurochemical profile differentiation of glioma induced by cancer stem cells expressing WIF1: a 1H-MRS longitudinal study at 14.1T2014. International Society for Magnetic Resonance in Medicine, Milan, May 10-16, 2014.
In vivo 13C MRS in the mouse brain at 14.1 T and metabolic flux quantification during infusion of [1,6-13C2] Glucose2014. International Society for Magnetic Resonance in Medicine, Milan, May 10-16, 2014.
Lactate brain metabolism in different mouse strains probed by hyperpolarized 13C MRS4th International DNP Symposium, Copenhagen, Denmark, August 28-31, 2013.
Which prior knowledge? Quantification of in vivo brain (13) C MR spectra following (13) C glucose infusion using AMARESMagnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. 2013. DOI : 10.1002/mrm.24406.
Cerebral glutamine metabolism under hyperammonemia determined in vivo by localized H-1 and N-15 NMR spectroscopyJournal Of Cerebral Blood Flow And Metabolism. 2012. DOI : 10.1038/jcbfm.2011.173.
GLIAL GLYCOLYTIC GAPDH ACTIVITY MODULATES THE RESTING CEREBRAL METABOLIC RATE OF GLUCOSE AND CA+2- DEPENDENT EXCITATORY NEUROTRANSMITTER RELEASE2011. Brain 2011, Barcelona, Spain, 25-28 May, 2011. p. 133.
Impact of the prior knowledge on the quantification of in vivo 13C spectra using two different algorithms: LCModel and AMARES2011. ISMRM 19th Annual Scientific Meeting, Montreal, Canada, 7-13 May 2011.
Imaging the in vivo effect of hyperammonemia in the rat brain: a Spectroscopic Imaging and Diffusion Tensor Imaging study2011. BRAIN’11 & BRAINPET’11, Barcelona, Spain, 24-28 May 2011.
Evaluation of glial metabolic fluxes in vivo with [2-13C] acetate infusion in mouse brain by 1H-[13C] NMR spectroscopy2011. ESMRMB CONGRESS 2011 28th Annual Scientific Meeting, Leipzig,Germany, October 6-8, 2011.
In Vivo Assessment of Neuronal Metabolic Fluxes in Mouse Brain by 1H-[13C] NMR Spectroscopy2011. ISMRM 19th Annual Meeting & Exhibition, Montréal, Québec, Canada, May 7-13, 2011.
Cerebral metabolic compartmentation determined by high resolution in vivo 13C NMR spectroscopySwiss Society for Neuroscience Annual Meeting 2011, Basel, Switzerland, March 26, 2011.
Brain metabolism by in vivo 13C NMR spectroscopy25th International Symposium on Cerebral Blood Flow, Metabolism and Function & 10th International Conference on Quantification of Brain Function with PET, Barcelona, Spain, May 25-28, 2011..
In vivo simultaneous measurement of glutamine synthetase and glutamate dehydrogenase activity in the hyperammonemic rat brain using localized 1H and 15N MRS2010. ISMRM-ESMRMB joint Annual Meeting, Stockholm, Sweden, 1-7 May, 2010.
Imaging glutamine synthesis rates in the hyperammonemic rat brain2010. ISMRM-ESMRMB joint Annual Meeting, Stockholm, Sweden, 1-7 May, 2010.
In vivo Magnetic Resonance Spectroscopy (MRS) studies of brain metabolism during ammonia infusion2010. 9th International Conference on Brain Energy Metabolism, Budapest, 7-10 July 2010.
Simultaneous Localized in vivo 1H and 15N MRS of Glutamine Synthesis in the hyperammonaemic rat brain2009. ISMRM 17th Annual Scientific Meeting, Hawaii, 18-19 April.
In vivo localized 15N and 1H MRS in the hyperammonaemic rat brain at 9.4T2009. ESMRMB, Antalya, TR, October 1-3.
MEASUREMENT OF GLUTAMINE SYNTHESIS RATE IN THE HYPERAMMONAEMIC RAT BRAIN USING IN VIVO 1H AND 15N MRS2009. INTERNATIONAL SYMPOSIUM ON HEPATIC ENCEPHALOPATHY, Valencia, Spain, September 17-19.
BISEP-based, Ultra-short TE 1H–[13C] NMR Spectroscopy of the Rat Brain at 14.1 T2009. ISMRM 17th Scientific Meeting & Exhibition, Honolulu, Hawai’i, USA, April 18-24, 2009.
Glutamine synthesis rate in the hyperammonaemic rat brain using simultaneous localized in vivo H-1 and N-15 MRS2009. 24th International Symposium on Cerebral Blood Flow and Metabolism/9th International Conference on Quantification of Brain Function with PET, Chicago, IL, Jun 29-Jul 03, 2009. p. S609-S610.
Measurements of glial metabolic fluxes with C-11-acetate using positron emission and an adapted NMR-based metabolic modeling approach2009. 24th International Symposium on Cerebral Blood Flow and Metabolism/9th International Conference on Quantification of Brain Function with PET, Chicago, IL, Jun 29-Jul 03, 2009. p. S460-S461.
Sélection de publications
supervisor: D. Pavuna // advisor: J. Generosi, Feb. 2007
|Master Project (SNOM)|