Camille Goemans
EPFL SV GHI UPGOEMANS
SV 2539 (Bâtiment SV)
Station 19
1015 Lausanne
Web site: Web site: https://www.epfl.ch/labs/upgoemans/
EPFL SV GHI UPGOEMANS
SV 2539 (Bâtiment SV)
Station 19
1015 Lausanne
Web site: Web site: https://sv.epfl.ch/education
Biography
Camille's research focuses on understanding how antibiotics and non-antibiotic drugs affect the diverse bacteria from the human gut microbiota and how they contribute to dysbiosis and the development of antibiotic resistance. To achieve this goal, she combines systems approaches with molecular microbiology, bacterial genetics and biochemistry.She obtained her Bachelor’s and Master’s degrees in Biomedical Sciences from the UCLouvain, Belgium, after which she completed her PhD (FRIA national fellowship) at the de Duve Institute, Belgium, in the laboratory of Prof. Jean-François Collet. Her primary focus was to elucidate bacterial responses to oxidative stress combining molecular microbiology with biochemistry. She then pursued post-doctoral studies at the European Molecular Biology Laboratory (EMBL) with an EMBO post-doctoral fellowship, in the laboratory of Dr. Nassos Typas, where she gained deep expertise into systems biology focusing on the impact of antibiotics on the human gut microbiota.
Camille's work has been published in top journals and her discoveries were highlighted by national and international press. She has received numerous awards and honors for her research, including the FNRS Yourassowsky Award for best PhD Thesis (Belgium, 2020), the Christiane Nusslein-Volhard Foundation Award (Germany, 2019), the Global Grants for Gut Health Best Paper Award by Nature (2021) and the l’Oreal/UNESCO for Women in Science Award (Germany, 2020).
Publications
Infoscience publications
2024
Bactericidal effect of tetracycline in E. coli strain ED1a may be associated with ribosome dysfunction
Nature Communications. 2024. DOI : 10.1038/s41467-024-49084-5.Systematic mapping of antibiotic cross-resistance and collateral sensitivity with chemical genetics
bioRxiv. 2024. DOI : 10.1101/2024.01.25.576750.2023
A molecular device for the redox quality control of GroEL/ES substrates
Cell. 2023. DOI : 10.1016/j.cell.2023.01.013.2021
Unravelling the collateral damage of antibiotics on gut bacteria
Nature. 2021. DOI : 10.1038/s41586-021-03986-2.2020
How the assembly and protection of the bacterial cell envelope depend on cysteine residues
Journal of Biological Chemistry. 2020. DOI : 10.1074/jbc.REV120.011201.The functional proteome landscape of Escherichia coli
Nature. 2020. DOI : 10.1038/s41586-020-3002-5.2019
Stress-induced chaperones: a first line of defense against the powerful oxidant hypochlorous acid
F1000Research. 2019. DOI : 10.12688/f1000research.19517.1.2018
CnoX Is a Chaperedoxin: A Holdase that Protects Its Substrates from Irreversible Oxidation
Molecular Cell. 2018. DOI : 10.1016/j.molcel.2018.04.002.An essential thioredoxin is involved in the control of the cell cycle in the bacterium Caulobacter crescentus
Journal of Biological Chemistry. 2018. DOI : 10.1074/jbc.RA117.001042.The Chaperone and Redox Properties of CnoX Chaperedoxins Are Tailored to the Proteostatic Needs of Bacterial Species
mBio. 2018. DOI : 10.1128/mBio.01541-18.2014
Folding mechanisms of periplasmic proteins
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 2014. DOI : 10.1016/j.bbamcr.2013.10.014.A New Role for Escherichia coli DsbC Protein in Protection against Oxidative Stress
Journal of Biological Chemistry. 2014. DOI : 10.1074/jbc.M114.554055.Teaching & PhD
Teaching
Life Sciences Engineering