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Camille Goemans

EPFL SV GHI UPGOEMANS
SV 2539 (Bâtiment SV)
Station 19
1015 Lausanne

EPFL SV GHI UPGOEMANS
SV 2539 (Bâtiment SV)
Station 19
1015 Lausanne

EPFL SV GHI UPGOEMANS
SV 2539 (Bâtiment SV)
Station 19
1015 Lausanne

EPFL SV GHI UPGOEMANS
SV 2539 (Bâtiment SV)
Station 19
1015 Lausanne

Camille's research focuses on understanding how antibiotics and non-antibiotic drugs affect the diverse bacteria from the human gut microbiota and how they contribute to dysbiosis and the development of antibiotic resistance. To achieve this goal, she combines systems approaches with molecular microbiology, bacterial genetics and biochemistry.
She obtained her Bachelor's and Master's degrees in Biomedical Sciences from the UCLouvain, Belgium, after which she completed her PhD (FRIA national fellowship) at the de Duve Institute, Belgium, in the laboratory of Prof. Jean-François Collet. Her primary focus was to elucidate bacterial responses to oxidative stress combining molecular microbiology with biochemistry. She then pursued post-doctoral studies at the European Molecular Biology Laboratory (EMBL) with an EMBO post-doctoral fellowship, in the laboratory of Dr. Nassos Typas, where she gained deep expertise into systems biology focusing on the impact of antibiotics on the human gut microbiota.
Camille's work has been published in top journals and her discoveries were highlighted by national and international press. She has received numerous awards and honors for her research, including the FNRS Yourassowsky Award for best PhD Thesis (Belgium, 2020), the Christiane Nusslein-Volhard Foundation Award (Germany, 2019), the Global Grants for Gut Health Best Paper Award by Nature (2021) and the l'Oreal/UNESCO for Women in Science Award (Germany, 2020).

2025

Mining the gut microbiota for defluorination activity

C. Goemans

Trends in Biochemical Sciences. 2025. DOI : 10.1016/j.tibs.2025.07.003.

2024

Systematic mapping of antibiotic cross-resistance and collateral sensitivity with chemical genetics

N. SakenovaE. CacaceA. OrakovF. HuberV. Varik  et al.

Nature Microbiology. 2024. DOI : 10.1038/s41564-024-01857-w.

Systematic mapping of antibiotic cross-resistance and collateral sensitivity with chemical genetics

N. SakenovaE. CacaceA. OrakovF. HuberV. Varik  et al.

2024

Bactericidal effect of tetracycline in E. coli strain ED1a may be associated with ribosome dysfunction

I. KhusainovN. RomanovC. GoemansB. TuroňováC. E. Zimmerli  et al.

Nature Communications. 2024. DOI : 10.1038/s41467-024-49084-5.

2023

A molecular device for the redox quality control of GroEL/ES substrates

E. DupuyS. E. Van der VerrenJ. LinM. A. WilsonA. V. Dachsbeck  et al.

Cell. 2023. DOI : 10.1016/j.cell.2023.01.013.

2021

Unravelling the collateral damage of antibiotics on gut bacteria

L. MaierC. V. GoemansJ. WirbelM. KuhnC. Eberl  et al.

Nature. 2021. DOI : 10.1038/s41586-021-03986-2.

2020

The functional proteome landscape of Escherichia coli

A. MateusJ. HevlerJ. BobonisN. KurzawaM. Shah  et al.

Nature. 2020. DOI : 10.1038/s41586-020-3002-5.

How the assembly and protection of the bacterial cell envelope depend on cysteine residues

J.-F. ColletS.-H. ChoB. I. IorgaC. V. Goemans

Journal of Biological Chemistry. 2020. DOI : 10.1074/jbc.REV120.011201.

2019

Stress-induced chaperones: a first line of defense against the powerful oxidant hypochlorous acid

C. V. GoemansJ.-F. Collet

F1000Research. 2019. DOI : 10.12688/f1000research.19517.1.

2018

An essential thioredoxin is involved in the control of the cell cycle in the bacterium Caulobacter crescentus

C. V. GoemansF. BeaufayK. WahniI. Van MolleJ. Messens  et al.

Journal of Biological Chemistry. 2018. DOI : 10.1074/jbc.RA117.001042.

The Chaperone and Redox Properties of CnoX Chaperedoxins Are Tailored to the Proteostatic Needs of Bacterial Species

C. V. GoemansF. BeaufayI. S. ArtsR. AgrebiD. Vertommen  et al.

mBio. 2018. DOI : 10.1128/mBio.01541-18.

CnoX Is a Chaperedoxin: A Holdase that Protects Its Substrates from Irreversible Oxidation

C. V. GoemansD. VertommenR. AgrebiJ.-F. Collet

Molecular Cell. 2018. DOI : 10.1016/j.molcel.2018.04.002.

2014

Folding mechanisms of periplasmic proteins

C. GoemansK. DenoncinJ.-F. Collet

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 2014. DOI : 10.1016/j.bbamcr.2013.10.014.

A New Role for Escherichia coli DsbC Protein in Protection against Oxidative Stress

K. DenoncinD. VertommenI. S. ArtsC. V. GoemansS. Rahuel-Clermont  et al.

Journal of Biological Chemistry. 2014. DOI : 10.1074/jbc.M114.554055.

PhD Students

Rodriguez Valentin, Maydaniuk Dustin Troy, Farano Anna Carla, Müller Katharina

Courses

Cellular and molecular biology I

BIO-205

The course covers the regulation of gene expression, which translates the information contained in the genome into function, by adjusting the levels and activities of mRNAs and proteins to the needs of specific cells, tissues and environments. A particular emphasis is given on experimental methods.

General Biology

BIOENG-110

The purpose of the course is to provide a general overview of the biology of cells and organisms. We will discuss this in the context of cell and organ life, focusing on the regulatory principles you will encounter in your biology studies.

General chemistry

CH-100

This course covers essential notions in general chemistry, relative to matter and its structure, equilibriums and chemical reactions, for life science students. The lectures and exercise sessions provide the knowledge and methodology required to solve general chemistry exercises.

Practical - Goemans Lab

BIO-621

The students will get practical experience in (i) how to cultivate diverse bacteria (ii) how to treat them with antibiotics or (iii) with bacteriophages that they will isolate themselves from the environment.