Christian Iseli
EPFL SV PTECH BICC
AAB 1 19 (Bâtiment AAB)
Station 19
1015 Lausanne
+41 21 693 75 36
Office: AAB 1 19
EPFL › SV › PTECH › BICC
Website: https://bix.epfl.ch
EPFL SV PTECH BICC
AAB 1 19 (Bâtiment AAB)
Station 19
1015 Lausanne
+41 21 693 75 36
Office: AAB 1 19
EPFL › SV › SV-SSV › SSV-ENS
Website: https://sv.epfl.ch/education
EPFL SV PTECH BICC
AAB 1 19 (Bâtiment AAB)
Station 19
1015 Lausanne
+41 21 693 75 36
Office: AAB 1 19
EPFL › SV › SV-DEC › CF-SV
Website: https://sv.epfl.ch/Council
- Variant-specific pathophysiological mechanisms of AFF3 differently influence transcriptome profiles
Genome Medicine. 2024-05-30. DOI : 10.1186/s13073-024-01339-y.- Inhibition of anti-tumor immunity by melanoma cell-derived Activin-A depends on STING
Frontiers In Immunology. 2024-01-18. DOI : 10.3389/fimmu.2023.1335207.- A phase 1 trial of adoptive transfer of vaccine-primed autologous circulating T cells in ovarian cancer
Nature Cancer. 2023-09-21. DOI : 10.1038/s43018-023-00623-x.- Chromosome-level organization of the regulatory genome in the Drosophila nervous system
Cell. 2023-08-31. DOI : 10.1016/j.cell.2023.07.008.- Epigenetic silencing of selected hypothalamic neuropeptides in narcolepsy with cataplexy
Proceedings Of The National Academy Of Sciences Of The United States Of America. 2023-05-01. DOI : 10.1073/pnas.2220911120.- DNA modifications impact natural transformation of Acinetobacter baumannii
Nucleic Acids Research. 2023. DOI : 10.1093/nar/gkad377.- Energy-harnessing problem solving of primordial life: Modeling the emergence of catalytic host-nested parasite life cycles
PLOS ONE. 2023. DOI : 10.1371/journal.pone.0281661.- Revisiting the specificity and ability of phospho-S129 antibodies to capture alpha-synuclein biochemical and pathological diversity
Npj Parkinsons Disease. 2022-10-20. DOI : 10.1038/s41531-022-00388-7.- SPICA: Swiss portal for immune cell analysis
Nucleic Acids Research. 2022-01-07. DOI : 10.1093/nar/gkab1055.- Essential role of Cp190 in physical and regulatory boundary formation
Science Advances. 2022. DOI : 10.1126/sciadv.abl8834.- Unexpected post‐glacial colonisation route explains the white colour of barn owls ( Tyto alba ) from the British Isles
Molecular Ecology. 2022. DOI : 10.1111/mec.16250.- Cell-autonomous inflammation of BRCA1-deficient ovarian cancers drives both tumor-intrinsic immunoreactivity and immune resistance via STING
Cell Reports. 2021. DOI : 10.1016/j.celrep.2021.109412.- CTCF loss has limited effects on global genome architecture in Drosophila despite critical regulatory functions
Nature Communications. 2021. DOI : 10.1038/s41467-021-21366-2.- Blood virosphere in febrile Tanzanian children
Emerging Microbes & Infections. 2021-01-01. DOI : 10.1080/22221751.2021.1925161.- Virosaurus A Reference to Explore and Capture Virus Genetic Diversity
Viruses-Basel. 2020-11-01. DOI : 10.3390/v12111248.- Neighbor predation linked to natural competence fosters the transfer of large genomic regions in Vibrio cholerae
eLife. 2019-09-03. DOI : 10.7554/eLife.48212.- MAR-Mediated transgene integration into permissive chromatin and increased expression by recombination pathway engineering
Biotechnology And Bioengineering. 2017. DOI : 10.1002/bit.26086.- The SIB Swiss Institute of Bioinformatics' resources: focus on curated databases
Nucleic Acids Research. 2016. DOI : 10.1093/nar/gkv1310.- ZFN-Site searches genomes for zinc finger nuclease target sites and off-target sites
BMC Bioinformatics. 2011. DOI : 10.1186/1471-2105-12-152.- Probabilistic base calling of Solexa sequencing data
BMC bioinformatics. 2008. DOI : 10.1186/1471-2105-9-431.- A Circuit for the Temperature Compensation of Capacitive Sensors
1996. p. 381-384. DOI : 10.1109/ISCAS.1996.539909.- Spyder
Lausanne, EPFL, 1996. DOI : 10.5075/epfl-thesis-1476.Teaching & PhD
Courses
Bioinformatic Analysis of RNA-sequencing (Spring)
BIO-693(b)
This course will take place in Spring 2026, dates and place to be determined. It introduces the workflows and techniques that are used for the analysis of bulk and single-cell RNA-seq data. It empowers students to understand and analyze their own data.
Methods: omics in biomedical research
BIOENG-519
High-throughput methodologies broadly called Omics allow to characterize the complexity and dynamics of any biological system. This course will provide a general description of different methods related to the Omics field followed by hands-on rotations in participating technological platforms.