EPFL SB SB-SCGC SCGC-ENS
PhD Thesis in physical organic chemistry at the University of Bourgogne Franche-Comté (Besançon, France) / Ecole Normale Supérieure de Cachan (Paris, France)
Habilitation à Diriger les Recherches (HDR) in chemistry at the Ecole Normale Supérieure de Cachan (Paris, France)
Fields of expertise
PublicationsCycloaddition of some arylnitriloxides with 3-methylenephtalide: electrocatalytic openning of the adduct C. Roussel, K. Ciamala, P. Audebert, J. Vebrel, New Journal of Chemistry, 23: 989-992, 1999. Contribution of microwaves in organic synthesis: statement of a methodology for the microwave-induced preparation of benzofuran-2(3H)-one and its comparison with classical heating P. Concalo, C. Roussel, J-M. Melot, J. Vebrel, Journal of the Chemical Society Perking Trans. 2, 2111-2115, 1999. Revisiting the addition of nitriloxides on protoanemonine. A new access to (2E)-3-(3'-arylisoxazol-5'-yl)propenoic acids C. Roussel, R. Fihi, K. Ciamala, P. Audebert, J. Vebrel, New Journal of Chemistry, 24: 471-476, 2000. The [3 2] cycloaddition of diphenyldiazomethane and ethyl diazoacetate with itaconic anhydride. A new access to spiranic cyclopropane derivatives C. Roussel, K. Ciamala, J-M. Melot, J. Vebrel, C. Riche, Journal of Chemical research (s), 9: 449-451, 2002. Spiroheterocycles from reaction of nitrones with methylene-gamma-butyrolactones and some of their rearrangements C. Roussel, R. Fihi, K. Ciamala, J. Vebrel, T. Zair, C. Riche, Organic and Biomolecular Chemistry, 1: 2689-2698, 2003. Mechanistic aspect of on-line electrochemical tagging of free L-cysteine residues during electrospray ionisation for mass spectrometry in protein analysis C. Roussel, T. C. Rohner, H. Jensen, H. H. Girault, ChemPhysChem, 4: 200-206, 2003. Microfluidic systems in proteomics N. Lion, T. C. Rohner, L. Dayon, I. L. Arnaud, E. Damoc, N. Youhnovski, Z.-Y. Wu, C. Roussel, J. Josserand, H. Jensen, J. S. Rossier, M. Przybylski, H. H. Girault, Electrophoresis, 24: 3533-3562, 2003. On-line cysteine modification for protein analysis: new probes for electrochemical tagging nanospray mass spectrometry C. Roussel, L. Dayon, H. Jensen, and H. H. Girault, Journal of Electroanalytical Chemistry, 570: 187-199, 2004. Generation of mass tags by the inherent electrochemistry of electrospray for protein mass spectrometry C. Roussel, L. Dayon, N. Lion, T. C. Rohner, J. Josserand, J. S. Rossier, H. Jensen, H. H. Girault, Journal of the American Society for Mass Spectrometry, 15: 1767-1779, 2004. On-line electrochemical tagging of free cysteine during nanospray ionisation for mass spectrometry analysis C. Roussel, L. Dayon, T. C. Rohner, N. Lion, H. H. Girault, Biophotonics New Frontier: From Genome to Proteome, Proceedings of Spie, 5461: 30-37, 2004. Polyelectrolyte modified short microchannel for cation separation X. Bai, C. Roussel, H. Jensen, and H. H. Girault, Electrophoresis, 25: 931-935, 2004. On-line electrochemical tagging of free cysteines in peptides during nanospray ionisation mass spectrometry: An Overview L. Dayon, C. Roussel, H. H. Girault, Chimia, 58: 204-207, 2004. On-Line counting of cysteine residues in peptides during electrospray ionization by electrogenerated tags and their application to protein identification L. Dayon, C. Roussel, M. Prudent, N. Lion, H. H. Girault. Electrophoresis, 26: 238-247, 2005. Antioxidant sensors based on DNA-modified electrodes J. F. Liu, C. Roussel, G. Lagger, P. Tacchini, and H. H. Girault, Analytical Chemistry, 77: 7687-7694, 2005. Size-selective separation of Gold nanoparticles using isoelectric focusing electrophoresis (IEF) I. L. Arnaud, J.-P. Abid, C. Roussel, H. H. Girault, Chemical Communications, 787-788, 2005. Salt removal during off-gel electrophoresis of protein samples I. L. Arnaud, J. Josserand, H. Jensen, N. Lion, C. Roussel, H. H. Girault, Electrophoresis, 26: 1650-1658, 2005. Probing cysteine reactivity in proteins by Mass Spectrometric EC-tagging L. Dayon, C. Roussel, and H. H. Girault, Journal of Proteome Research, 5: 793-800, 2006. Immobilized pH gradient gel cell to study the pH dependence of drug lipophilicity H.-T. Lam, C. M. Pereira, C. Roussel, P.-A. Carrupt, H. H. Girault, Analytical Chemistry, 78: 1503-1508, 2006. 2,3-diphenyl-2,3-dihydrospiro[1,3-oxazole-5(4H),1'(3'H)-2-benzofuran]-3'-one J.-C. Daran, R. Fihi, C. Roussel, N. Laghrib, M. Azrour, K. Ciamala, J. Vebrel, Acta Crystallographica E, 62: o329-o331, 2006. Electrochemical generation of Cu(I) complexes in aqueous solutions studied by on-line mass spectrometry M. Prudent, C. Roussel, H. H. Girault, Electrochemistry Communications, 9: 2067-2074, 2007. Specific on-plate enrichment of phosphorylated peptides for direct MALDI-TOF MS analysis L. Qiao, C. Roussel, J. J. Wan, P. Y. Yang, H. H. Girault, B. H. Liu, Journal of Proteome Research, 6: 4763-4769, 2007. Reaction of 3-methylenedihydro-(3H)-furan-2-one with diazoalkanes. Syntheses and crystal structures of spiranic cyclopropyl compounds C. Roussel, K. Ciamala, J. Vebrel, M. Knorr, M. M. Kubicki, Heterocycles, 71: 1517-1528, 2007. MALDI in-source photo-oxidation reactions for on-line peptide tagging L. Qiao, C. Roussel, J. J. Wan, J. L. Kong, P. Y. Yang, H. H. Girault, B. H. Liu, Angewandte Chemie, International Edition, 47: 2646-2648, 2008. Protoporphyrin IX sensitized titanium oxide gel electrode S. X. Tan, B. Su, C. Roussel, H. H. Girault, Inorganica Chimica Acta, 361: 746-760, 2008. About the electrospray ionization source in Mass Spectrometry: electrochemistry and on-chip reactions M. Prudent, M. A. Méndez, C. Roussel, B. Su, N. Lion, J. S. Rossier, H. H. Girault, Chimia, 63: 283-287, 2009. Reactivity of arynitriloxides and C-aroyl-N-phenylnitrones with 3-methylenedihydro-(3H)-furan-2-one and itaconic anhydride C. Roussel, K. Ciamala, J. Vebrel , C. Riche, Heterocycles, 78: 1977-1991, 2009. Photocatalytic discoloration of aqueous malachite green solutions by UV-illuminated TiO2 nano-particles under air and nitrogen atmospheres: effects of counter-ions and pH J.A. Rengifo-Herrera, L.R. Pizzo, M.N. Blanco, C. Roussel, C. Pulgarin, Photochemical and photobiological sciences, 10: 29-34, 2011. RF-plasma pretreatment of surfaces leading to TiO2 coatings with improved optical absorption and OH radical-production O. Baghriche, S. Rtimi, C. Pulgarin, C. Roussel, J. Kiwi, Applied Catalysis B, 130-131: 65-72, 2013. Hyperpolarized 13C MRI contrast agent generated by shining light on a pure glucose metabolic product for probing metabolism in vivo in real time T.R. Eichhorn, Y. Takado, N. Salameh, A. Capozzi, T. Cheng, J.-N. Hyacinthe, M. Mishkovsky, C. Roussel, A. Comment, Proceedings of the national academy of sciences of the united states of America, 2013, 110, 18064-18069. Standard addition strip for quantitative electrostatic spray ionization mass spectrometry analysis: Determination of caffeine in drinks. E. Tobolkina, L. Qiao, C. Roussel and H. H. Girault, Talanta, 2014, 130, 377-381. Optimal glass-forming solvent brings sublimation dynamic nuclear polarization to 129Xe hyperpolarization biomedical imaging standards. A. Capozzi, C. Roussel, A. Comment and J.-N. Hyacinthe, Journal of Physical Chemistry C, 2015, 119, 5020-5025. Photo-Induced non-Persistent Radicals as Polarizing Agents for X-Nuclei Dissolution-DNP. A. Capozzi, J.-N. Hyacinthe, T. Cheng, T. Eichhorn, G. Boero, C. Roussel, J. Van der Klink and A. Comment, Journal of Physical Chemistry C, 2015, 119, 22632-22639. Preparation, kinetics, mechanism and properties of semi-transparent photocatalytic stable films active in dye degradation L. Suarez, C. Pulgarin, C. Roussel and J. Kiwi, Applied Catalysis A, 2016, 516, 70-80. Experimental and theoretical studies on electropolymerization of polar amino acids on platinum electrode T. Alhedabi, H. Cattey, C. Roussel, V. Blondeau-Patissier, T. Gharbi and G. Herlem, Material Chemistry and Physics, 2017, 185, 183-194. Thermal annihilation of photo-induced radicals following dynamic nuclear polarization to produce transportable frozen hyperpolarized 13C-substrates A. Capozzi, T. Cheng, G. Boero, C. Roussel and A. Comment, Nature Communications, 2017, 8, 15757. Quantification of THC in cannabis plants by Fast-HPLC-DAD: a promising method for routine analyses C. Burnier, P. Esseiva and C. Roussel, Talanta, 2019, 192, 135.
PatentsChemical wall-plug product comprises separate components which, when mixed, undergo simultaneous expansion and polymerization-crosslinking reactions to form an expanded 3-dimensional thermoset structure J. Vebrel, P. Goncalo, C. Roussel, J. Vuillermoz, PCT/FR2000/01132, WO2000/66673-A, 2000. Ionisation device L. Qiao, P.Y. Yang, B. Liu, N. Lion, C. Roussel, H.H. Girault, PCT/EP2008/000140, WO2008/083966, 2008. Solid-phase extraction and ionisation device B. Liu, L. Qiao, N. Lion, J.J. Wan, M. Prudent, C. Roussel, P.Y. Yang, H.H. Girault, PCT/EP2008/5347, WO2009/003673, 2009. Method for the generation of radicals for Dynamic Nuclear Polarization and uses thereof for NMR, MRS and MRI T.R. Eichhorn, C. Roussel, A. Comment, PCT/EP2013/709430, WO2014/139573, 2014.
Teaching & PhD
- Chemistry and Chemical Engineering,
This course aims at the acquisition of essential notions on the structure of matter, chemical equilibria and reactivity. Theoretical teaching and exercise provide the methodology to analyze and solve by reasoning and calculation novel problems of general ...Auditeurs, 2018-2019, Autumn semester, language : french
Section of Chemistry and Chemical Engineering, 2018-2019, Bachelor semester 5, language : french