Cristina Ramona Cudalbu

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Field of Expertise
  • In vivo proton, phosphorus, carbon and nitrogen MR Spectroscopy 
  • Chronic  Hepatic Encephalopathy, Hyperammonemia - https://actu.epfl.ch/news/when-liver-disease-affects-the-brain/
  • Brain metabolites quantification and macromolecules
  • In vivo proton Spectroscopic Imaging 
  • Diffusuion weighted Spectroscopy
  • Brain tumors 
  • Dynamic nuclear polarization 

Position
Senior Research Staff Scientist & 9.4T MRI Operational Manager, CIBM MRI AIT (EPFL)

PubMed
Scholar google

EPFL ENT-R CIBM-AIT
CH F0 628 (Bâtiment CH)
Station 6
CH-1015 Lausanne

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Administrative data

Infoscience publications

Research

Current work

Development: implement/validate new acquisition and quantification techniques for in vivo proton, phosphorous, carbon, nitrogen MRS
  • Implement new acquisition techniques for fast spectroscopic imaging and diffusion spectroscopy
  • Implement new techniques for brain macromolecules quantification

Animal models: 
  • Chronic liver failure/chronic hepatic encephalopathy, 
  • Brain tumors, 
  • Creatine deficiencies, etc

Grants

  • 2019-2021 - Co-applicant in the Innosuisse - Suisse Innovation Agency application "Pearl injectable implants, a solution for the reconstruction of ultra-large volumes of soft tissues post-injury"
  • 2018-2022 - Vice-coordinator in the H2020-MSCA-ITN-2018 application " INtegrating Magnetic Resonance SPectroscopy and Multimodal Imaging for Research and Education in MEDicine" (INSPiRE-MED, 813120) 
  • 2017-2021: Swiss National Science Foundation; grant n° 31003A-175778/1 to Braissant&Cudalbu. “Cerebral creatine deficiency syndromes: New in vivo AAV approaches to treat SLC6A8 deficiency.”
  • 2017-2021: Swiss National Science Foundation; grant n° 310030_173222/1 to Cudalbu&Braissant&McLin. “Translational Non-Invasive Metabolic Studies towards Novel Treatments of Chronic Hepatic Encephalopathy in Developing Brain, from 3D Organotypic Brain Cell Cultures to the In vivo Rat and Human Brain.”
  • 2017-2018: Co-applicant in the Swiss Cancer League application “Characterizing invasiveness of patient derived brain tumor transplants in mice by gene expression profiling in association with metabolite profiles obtained by magnetic resonance spectroscopy (MRS). A pilot project”, (PI Monika Hegi)
  • 2014-2016: Co-applicant in the Swiss Bridge Foundation application "Towards patient-specific treatments in glioblastoma: Comparison and validation of high-resolution imaging and molecular profiles of human glioblastoma and respective paired orthotopic xenografts in the mouse" (PI Andreas Hottinger)
  • 2014: PI for the Industrial grant VSL Pharmaceuticals Inc. 
  • 2013-2017: Co-applicant in FP7-PEOPLE Marie Curie Initial Training Network project "Transforming Magnetic Resonance Spectroscopy into a Clinical Tool" (TRANSACT)