The mission of Protein Production and Structure Core Facility (PTPSP) is to assist, advise and connect researchers in protein sciences and integrative structural biology, not only to allow them to achieve their own goals, but also to give them the opportunity to think further and differently. To achieve this mission, we provide a team of motivated experts in protein production, purification and characterization (biophysical and structural), high-end in-house instruments, and access to top-end structural biology facilities in Switzerland and worldwide. PTPSP is a hub where academic scientists, from within or outside the EPFL, novice or not, should feel welcome to learn, interact, share and intensify their knowledge, collaborations, and research opportunities.