Giovanna Ambrosini

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Safety Delegate

giovanna.ambrosini@epfl.ch +41 21 693 09 57

Citizenship: Italian and Swiss

+41 21 693 09 57
+41 21 693 88 36
Office: AAB 1 21
EPFL > VPO > VPO-SE > OHS > COSEC-SV

EPFL SV PTECH BICC
AAB 1 19 (Bâtiment AAB)
Station 19
1015 Lausanne

+41 21 693 88 36
Office: AAB 1 21
EPFL > SV > PTECH > BICC

Web site: Web site: https://bix.epfl.ch

EPFL SV ISREC UPBRI
SV 2830 (Bâtiment SV)
Station 19
1015 Lausanne

+41 21 693 88 36
Office: SV 2830
Office: AAB 1 21
EPFL > SV > ISREC > UPBRI

Web site: Web site: https://brisken-lab.epfl.ch

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Administrative data

Current Position

Senior Scientist, School of Life Sciences, Philipp Bucher Group, École Polythechnique Fédérale de Lausanne, Lausanne.

Honors

Admitted to the Collegio Ghislieri in Pavia for my Bachelor's degree at the University of Pavia. The Ghislieri College (Ital. Collegio Ghislieri), founded in 1567 by Pope Pius V, is one of the most ancient colleges in Pavia and co-founder of the IUSS, located in Pavia as well. Collegio Ghislieri is a 450 years old Italian institution committed to promote University studies on the basis of merit, hosting around 200 pupils (males and females) who attend all faculties in Pavia State University, offering them logistic and cultural opportunities such as scholarships, lectures, conferences, a 100.000 volumes library (the third one among private libraries in Northern Italy), foreign languages courses. Each year about 30 new students coming from all over the country are selected by public contest.

Professional course

University Assistant

University of Bern, Switzerland

1995-1997

Fellow in the EP Division ATD group at CERN

development of Data Acquisition Systems

1998-1999

Software Engineer

R&D department

Lightning Instrumentation SA, Lausanne

1999-2000

Systems Engineer

Linux Architect

Creative Electronics Systems, Geneva

2000-2002

Bioinformatician

Swiss Institute for Experimental Cancer Research (ISREC), Lausanne/Epalinges

2002-2007

Bioinformatician and software engineer

École Polytechnique Fédérale de Lausanne (EPFL), Lausanne

2007-current

Education

Ph.D. in Physics

High Energy Physics at CERN, Geneva, Switzerland

University of Pavia, Italy

Oct 1995.

Laurea, the italian equivalent of a Bachelors degree

in Mathematical and Physical Sciences

University of Pavia, Italy

July the 19th 1991.

Publications

Infoscience publications

PUBLICATIONS

Integrating distribution kinetics and toxicodynamics to assess repeat dose neurotoxicity in vitro using human BrainSpheres: a case study on amiodarone

C. Nunes; S. Proenca; G. Ambrosini; D. Pamies; A. Thomas et al.

Frontiers In Pharmacology. 2023-09-06. DOI : 10.3389/fphar.2023.1248882.

C. Iseli, G. Ambrosini, P. Bucher, and C. V. Jongeneel In PLoS ONE, volume 2, page e579, 2007.	Indexing strategies for rapid searches of short words in genome sequences
G. Ambrosini, V. Praz, V. Jagannathan, and P. Bucher In Nucleic Acids Res, volume 31, number 13, pages 3618-20, 2003.	Signal search analysis server

Giovanna Ambrosini

Safety Delegate

Current Position

Honors

Professional course

Education

Publications

Infoscience publications

PUBLICATIONS

Integrating distribution kinetics and toxicodynamics to assess repeat dose neurotoxicity in vitro using human BrainSpheres: a case study on amiodarone

MarrowQuant 2.0: A Digital Pathology Workflow Assisting Bone Marrow Evaluation in Experimental and Clinical Hematology

Epithelial-mesenchymal plasticity determines estrogen receptor positive breast cancer dormancy and epithelial reconversion drives recurrence

Abstract 2993: Intraductal xenografts model ERα-positive invasive lobular carcinoma of the breast

Contraceptive progestins with androgenic properties stimulate breast epithelial cell proliferation

Intraductal xenografts show lobular carcinoma cells rely on their own extracellular matrix and LOXL1

Insights gained from a comprehensive all-against-all transcription factor binding motif benchmarking study

The secreted protease Adamts18 links hormone action to activation of the mammary stem cell niche

EPD in 2020: enhanced data visualization and extension to ncRNA promoters

Common genetic variants associated with Parkinson's disease display widespread signature of epigenetic plasticity

Short-lived AUF1 p42-binding mRNAs of RANKL and BCL6 have two distinct instability elements each

PWMScan: a fast tool for scanning entire genomes with a position-specific weight matrix

MGA repository: a curated data resource for ChIP-seq and other genome annotated data

SMiLE-seq identifies binding motifs of single and dimeric transcription factors

The eukaryotic promoter database in its 30th year: focus on non-vertebrate organisms

SNP2TFBS - a database of regulatory SNPs affecting predicted transcription factor binding site affinity

The ChIP-Seq tools and web server: a resource for analyzing ChIP-seq and other types of genomic data

Influence of Rotational Nucleosome Positioning on Transcription Start Site Selection in Animal Promoters

The SIB Swiss Institute of Bioinformatics' resources: focus on curated databases

The Eukaryotic Promoter Database: expansion of EPDnew and new promoter analysis tools

Principles of ChIP-seq Data Analysis Illustrated with Examples

Nuclear Factor I genomic binding associates with chromatin boundaries

EPD and EPDnew, high-quality promoter resources in the next-generation sequencing era

Critical assessment of automated flow cytometry data analysis techniques

Nuclear factor I revealed as family of promoter binding transcription activators

ZFN-Site searches genomes for zinc finger nuclease target sites and off-target sites

A gene-rich, transcriptionally active environment and the pre-deposition of repressive marks are predictive of susceptibility to KRAB/KAP1-mediated silencing

KRAB-Zinc Finger Proteins and KAP1 Can Mediate Long-Range Transcriptional Repression through Heterochromatin Spreading

Nucleosome eviction from MHC class II promoters controls positioning of the transcription start site

Selected publications

All postal addresses and positions