Biographie

since 2018:
Adjoint du Doyen SV, Responsable Finance SV

since 2008:
 Adjoint du Doyen SV
 
 2002-2010: 
 Adjoint scientifique, FSV-LNC, EPFL
 
 2006-2008: 
 Adjoint de Section SSV
 
 2003-2004:
 coordinator (directeur) of the doctoral program in Neuroscience, EPFL Doctoral School
 
 1994-2001: 
 University of Lausanne 
 Stanford University 
 Institut Curie, Paris 
 
 Education: 
 ISREC, Epalinges (Switzerland).
 University of Konstanz (Germany)

TEACHING EXPERIENCE

- "Introduction Biologie Cellulaire I" to 1. year chemistry students 
 (EPFL, 2005-2006, 8h lecture per year, 8h exercises per year), in French
 
 - Histology of the Nervous Tissue and the Nervous system to 2. year medical students
 (University of Lausanne, 2000 – 2001, 8h per year), in French
 
 - Assistance in microscopy courses of General Histology to 2. year medical students 
 (University of Lausanne, 1997 – 2001, 56h per year), in French
 
 - Problem-based Teaching in Biochemisty (Metabolism and Nutrition) to 2. year medical students(University of Lausanne, 2000 – 2002, 8h per year), in French
 
 - Cellular Neuroscience Module: "Intracellular Trafficking" to 3. year biology students
 (University of Lausanne, 2003 – 2004, 6h per year), in French
 
 - "Membrane Dynamics" and "Plasticity" lectures in orientation Neuroscience course to 3. year life sciences BA students 
 (EPFL, 2005, 4h per year), in English
 
 - Master course "Biologie et biochimie cellulaire pour ingénieurs", to MA students in Microtechniques, Material Sciences, Informatics 
 (EPFL, 2006 - 2011, 28h lecture per year, 28h exercises per year), in English
 
 - Graduate course "Developmental Neurobiology"; Doctoral Schools EPFL/UNIL in Neuroscience 
 (EPFL/UniL, 2002 – 2006, 3h pro year), in English
 
 - Graduate course "Image acquisition and processing in biology", Doctoral Schools EPFL/UNIL in Neuroscience 
 (EPFL/UniL, 2004-2005, 21h per year), in English
 

RECENT PUBLICATIONS

- Steiner, P., Sarria, J.-C. F., Glauser, L., Magnin, S., Catsicas, S. and Hirling, H. (2002)
 Modulation of receptor cycling by Neuron-Enriched Endosomal Protein of 21 kDa 
 J. Cell Biol., 157, 1197-1209
 
 - Coppola, T., Frantz, C., Perret-Menoud, V., Gattesco, S., Hirling, H., and Regazzi, R. (2002)
 The pancreatic b-cell protein granuphilin binds Rab3 and Munc-18 and controls exocytosis 
 Mol. Biol. Cell, 13, 1906-1915
 
 - Sarria, J.-C. F., Catsicas, S., Hornung, J.-P. and Hirling, H. (2002)
 Developmental and spatial expression pattern of syntaxin 13 in the mouse central nervous system 
 Cell Tissue Res., 309, 209-218
 
 - Steiner, P., Sarria, J.-C. F., Huni, B., Marsault, R., Catsicas, S. and Hirling, H. (2002)
 Overexpression of neuronal Sec1 enhances axonal branching in hippocampal neurons 
 Neuroscience, 113, 893-905
 
 - Morgenthaler, F.D., Knott, G., Sarria, J.-C. F., Wang, X., Staple, J.K., Catsicas, S. and Hirling, H. (2003)
 Morphological and molecular heterogeneity in release sites of single neurons 
 Eur. J. Neurosci., 17, 1365-1374
 
 - Yersin, A., Hirling, H., Steiner, P., Magnin, S., Regazzi, R., Huni, B., Huguenot, P., De Los Rios, P., Dietler, G., Catsicas, S. and Kasas, S. (2003)
 Interactions between synaptic vesicle fusion proteins explored by atomic force microscopy
 Proc. Natl. Acad. Sci. USA, 100, 8736-8741
 
 - Uldy, M., Steiner, P., Zürich-Graf, M.-G., Béguin, P., Hirling, H., Honneger, P. , Dolci, W. and Thorens, B. (2004)
 Regulated Exocytosis of a H /myo-Inositol symporter at synapses and growth cones
 EMBO J., 23, 531-540
 
 - Meijering, E., Jacob, M., Sarria, J.-C. F., Steiner, P., Hirling, H., and Unser, M. (2004) 
 Design and Validation of a Tool for Neurite Tracing and Analysis in Fluorescence Microscopy Images
 Cytometry, 58A,167-176
 
 - Steiner, P., Kulangara, K., Sarria, J.-C. F ., Glauser, L., Regazzi, R. and Hirling, H. (2004)
 Reticulon 1-C/Neuroendocrine-Specific Protein-C interacts with SNARE proteins
 J. Neurochem., 89, 569-580
 
 - Debaigt, C., Hirling, H., Vincent, J.-P., Steiner, P. and Mazella, J (2004)
 Crucial Role of Neuron-Enriched Endosomal Protein of 21 KD in sorting between degradation and recycling of internalized G-protein coupled receptors
 J. Biol. Chem, 279 (34), 35687-35691
 
 - Saxena, S., Howe, C.L., Cosgaya, J.M., Steiner, P., Hirling, H., Chan, J.R., Weis, J. and Krüttgen, A. (2005) Differential endocytic sorting of p75NTR and TrkA in response to NGF: a role for late endosomes in TrkA trafficking
 Mol. Cell. Neurosci., 28, 571-587 
 
 - Beretta, F., Sala, C., Saglietti, L., Hirling, H., Sheng, M. and Passafaro, M. (2005)
 NSF interaction is important for direct insertion of GluR2 at synaptic sites
 Mol. Cell. Neurosci., 28, 650-660
 
 - Alberi, S., Boda, B., Steiner, P., Nikonenko, I., Hirling, H. and Muller, D. (2005)
 Interference with the endosomal protein NEEP21 affects AMPA receptor mediated synaptic transmission and plasticity in the hippocampus
 Mol. Cell. Neurosci., 29, 313-319
 
 - Kasas, S., Wang, X., Hirling, H., Marsault, R., Huni, B., Yersin, A., Regazzi, R., Grenningloh, G., Riederer, B., Forrò, L., Dietler, G. and Catsicas, S. (2005)
 Superficial and Deep Changes of Cellular Mechanical Properties Following Cytoskeleton Disassembly
 Cell Motil Cytoskeleton, 62, 124-132
 
 Steiner, P., Alberi, S, Kulangara, K., Yersin, A., Sarria, JCF., Regulier, E., Kasas, S., Dietler, G., Muller, D., Catsicas, S. and Hirling, H. (2005)
 Interactions between NEEP21, GRIP1 and GluR2 regulate sorting and recycling of the glutamate receptor subunit GluR2 
 EMBO J. , 24, 2873-2884
 
 - Genoud, C., Quariauxx, C., Steiner, P., Hirling, H., Welker, E. and Knott, G.W. (2006) 
 Plasticity of astrocyte coverage and glutamate transmporter expression in adult mouse cortex
 PLoS Biology, 4, e343
 
 - Brissoni, B., Agostini, L., Kropf, M., Martinon, F., Swoboda, V., Lippens, S., Everett, H., Aebi, N., Janssens, S., Meylan, E., Felbermann-Corti, M., Hirling, H., Gruenberg, J, Tschopp, J and Burns, K. (2006)
 Intracellular trafficking of Interleukin-1 receptor I requires Tollip
 Current Biology, 16, 2265
 
 - Kulangara, K., Kropf, M., Glauser, L., Magnin, S., Alberi, S., Yersin, A. and Hirling, H. (2007) 
 Phosphorylation of GRIP1 regulates surface expression of glutamate receptors 
 J. Biol. Chem., 282 (4), 2395-2404 
 
 - Yersin, A., Hirling, H., Kasas, S., Roduit, C., Kulangara, K., Dietler, G., Lafont, F., Catsicas, S. and Steiner, P. (2007) 
 Elastic properties of the cell surface and trafficking of single AMPA receptors in living primary hippocampal neurons 
 Biophys. J., 92(12), 4482-4489 
 
 - Brunner, J.-M., Plattet, P., Majcherczyk, P., Zurbriggen, A., Wittek, R. and Hirling, H. (2007) 
 Canine distemper virus infection of primary hippocampal cells induces increase in extracellular glutamate and neurodegeneration 
 J. Neurochem., 103, 1184-1195 
 
 - Yap, C.C., Wisco, D., Kujala, P., Lasiecka, Z.M., Cannon, J.T., Chang, M.C., Hirling, H., Klumperman, J. and Winckler, B. (2008) 
 The somatodendritic endosomal regulator NEEP21 facilitates axonal targeting of L1/NgCAM 
 J. Cell Biol., 180, 827-842 
 
 - Kropf, M.,, Rey, G., Glauser, L., Kulangara, K., Johnsson, K. and Hirling, H. (2008) 
 Subunit-specific surface mobility of differentially labeled AMPA receptor subunits 
 Eur. J. Cell. Biol., 87, 763-778 
 
 -Rudinskiy, N., Grishchuk, Y., Vaslin, A., Puyal, J., Delacourte, A., Hirling, H., Clarke, P.G. and Luthi-Carter, R. (2009) 
 Calpain hydrolysis of alpha- and beta2-adaptins decreases clathrin-dependent endocytosis and may promote neurodegeneration. 
 J. Biol. Chem, 284, 12447-58 
 
 - Utvik, J.K., Haglerød, C., Mylonakou, M.N., Holen, T., Kropf, M., Hirling, H., Skare, O., Laake, P., Ottersen, O.P., Haug, F.M. and Davanger, S. (2009) 
 Neuronal enriched endosomal protein of 21 kDa colocalizes with glutamate receptor subunit GLUR2/3 at the postsynaptic membrane. 
 Neuroscience, 158, 96-104 
 
 - Mbefo, M.K., Paleologou, K.E., Boucharaba, A., Oueslati, A., Schell, H., Fournier, M., Olschewski, D., Yin, G., Zweckstetter, M., Masliah, E., Kahle, P.J., Hirling, H. and Lashuel, H.A. (2010) 
 Phosphorylation of synucleins by members of the Polo-like kinase family 
 J. Biol. Chem, 285, 2807-22