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Données administratives

Jocelin Grosse

jocelyn.grosse@epfl.ch

EPFL CIBM-PCI
CH F0 626 (Bâtiment CH)
Station 6
1015 Lausanne

Publications représentatives

Energy-dependent modulation of nucleus accumbens output via K-ATP channel activity

Astori, Simone , Zanoletti, Olivia , Grosse, Jocelyn , Sandi, Carmen
Published in Neuropsychopharmacology in 2026

Urolithin A abolishes high anxiety and rescues the associated mitochondria-related transcriptomic signatures and synaptic function

David Mallet; Doğukan Hazar Ülgen; Jocelyn Grosse; Olivia Zanoletti; Isabelle Guillot de Suduiraut; Anna S. Monzel; Davide D’Amico; Chris Rinsch; Martin Picard; Simone Astor; Carmen Sandi
Published in Biological Psychiatry in 2025

Blunted Glucocorticoid Responsiveness to Stress Causes Behavioral and Biological Alterations That Lead to Posttraumatic Stress Disorder Vulnerability

Monari, S.; Guillot de Suduiraut, I.; Grosse, J.; Zanoletti, O.; Walker, S.E.; Mesquita, M.; Wood, T.C.; Cash, D.; Astori, S.; Sandi, C
Published in Biological Psychiatry in 2024

Corticosterone administration immediately after peripuberty stress exposure does not prevent protracted stress-induced behavioral alterations

Laura Perez-Caballero, Isabelle Guillot de Suduiraut, Leire R. Romero , Jocelyn Grosse, Carmen Sandi, Raul Andero
Published in Psychoneuroendocrinology in 2024

Mitofusin-2 in nucleus accumbens D2-MSNs regulates social dominance and neuronal function

Ghosal, S.; Gebara, E.; Ramos-Fernández, E.; Chioino, A.; Grosse, J.; Guillot de Suduiraut, I.; Zanoletti, O.; Schneider, B.; Zorzano, A.; Astori, S., Sandi C.
Published in Cell Reports in 2023

Creatine transporter–deficient rat model shows motor dysfunction, cerebellar alterations, and muscle creatine deficiency without muscle atrophy

Duran-Trio, L.; Fernandes-Pires, G.; Grosse, J.; Soro-Arnaiz, I.; Roux-Petronelli, C.; Binz, P.-A.; De Bock, K.; Cudalbu, C.; Sandi, C.; Braissant, O
Published in Journal of Inherited Metabolic Disease in 2022

Deletion of Crtc1 leads to hippocampal neuroenergetic impairments associated with depressive-like behavior

herix, A.; Poitry-Yamate, C.; Lanz, B.; Zanoletti, O.; Grosse, J.; Sandi, C.; Gruetter, R.; Cardinaux, J.-R
Published in Molecular Psychiatry in 2022

ENAMPT actions through nucleus accumbens NAD+/SIRT1 link increased adiposity with sociability deficits programmed by peripuberty stress

Morató, L.; Astori, S.; Zalachoras, I.; Rodrigues, J.; Ghosal, S.; Huang, W.; De Suduiraut, I.G.; Grosse, J.; Zanoletti, O.; Cao, L; Sandi C.
Published in Science Advances in 2022

Opposite effects of stress on effortful motivation in high and low anxiety are mediated by CRHR1 in the VTA

Zalachoras, I.; Astori, S.; Meijer, M.; Grosse, J.; Zanoletti, O.; De Suduiraut, I.G.; Deussing, J.M.; Sandi, C.
Published in Science Advances in 2022

Stress-induced depressive-like behavior in male rats is associated with microglial activation and inflammation dysregulation in the hippocampus in adulthood

Brás, J.P.; Guillot de Suduiraut, I.; Zanoletti, O.; Monari, S.; Meijer, M.; Grosse, J.; Barbosa, M.A.; Santos, S.G.; Sandi, C.; Almeida, M.I
Published in Brain Behavior and Immunity in 2022

A new rat model of creatine transporter deficiency reveals behavioral disorder and altered brain metabolism

Duran-Trio, L.; Fernandes-Pires, G.; Simicic, D.; Grosse, J.; Roux-Petronelli, C.; Bruce, S.J.; Binz, P.-A.; Sandi, C.; Cudalbu, C.; Braissant, O.
Published in Scientific Reports in 2021

Astrocytic release of ATP through type 2 inositol 1,4,5-trisphosphate receptor calcium signaling and social dominance behavior in mice

Guillot de Suduiraut, I.; Grosse, J.; Ramos-Fernández, E.; Sandi, C.; Hollis, F.
Published in European Journal of Neuroscience in 2021

Mitofusin-2 in the Nucleus Accumbens Regulates Anxiety and Depression-like Behaviors Through Mitochondrial and Neuronal Actions

Gebara, E.; Zanoletti, O.; Ghosal, S.; Grosse, J.; Schneider, B.L.; Knott, G.; Astori, S.; Sandi, C.
Published in Biological Psychiatry in 2021

Probiotics improve the neurometabolic profile of rats with chronic cholestatic liver disease

Rackayová, V.; Flatt, E.; Braissant, O.; Grosse, J.; Capobianco, D.; Mastromarino, P.; McMillin, M.; DeMorrow, S.; McLin, V.A.; Cudalbu, C
Published in Scientific Reports in 2021

Amygdala GluN2B-NMDAR dysfunction is critical in abnormal aggression of neurodevelopmental origin induced by St8sia2 deficiency

Bacq, A.; Astori, S.; Gebara, E.; Tang, W.; Silva, B.A.; Sanchez-Mut, J.; Grosse, J.; Guillot de Suduiraut, I.; Zanoletti, O.; Maclachlan, C; Sandi., c
Published in Molecular Psychiatry in 2020

Metabolic signature in nucleus accumbens for anti-depressant-like effects of acetyl-l-carnitine

Cherix, A.; Larrieu, T.; Grosse, J.; Rodrigues, J.; McEwen, B.; Nasca, C.; Gruetter, R.; Sandi, C.
Published in Elife in 2020

Mitochondrial gene signature in the prefrontal cortex for differential susceptibility to chronic stress

Weger, M.; Alpern, D.; Cherix, A.; Ghosal, S.; Grosse, J.; Russeil, J.; Gruetter, R.; de Kloet, E.R.; Deplancke, B.; Sandi, C
Published in Scientific Reports in 2020

The glucocorticoid receptor in the nucleus accumbens plays a crucial role in social rank attainment in rodents

Papilloud, A.; Weger, M.; Bacq, A.; Zalachoras, I.; Hollis, F.; Larrieu, T.; Battivelli, D.; Grosse, J.; Zanoletti, O.; Parnaudeau, S; Sandi, C.
Published in Psychoneuroendocrinology in 2020

Longitudinal neurometabolic changes in the hippocampus of a rat model of chronic hepatic encephalopathy

Braissant, O.; Rackayová, V.; Pierzchala, K.; Grosse, J.; McLin, V.A.; Cudalbu, C
Published in Journal of Hepatology in 2019

Low vagal tone in two rat models of psychopathology involving high or low corticosterone stress responses

Huzard, D.; Ghosal, S.; Grosse, J.; Carnevali, L.; Sgoifo, A.; Sandi, C
Published in Psychoneuroendocrinology in 2019

Peripubertal stress-induced heightened aggression: modulation of the glucocorticoid receptor in the central amygdala and normalization by mifepristone treatment

Papilloud, A.; Veenit, V.; Tzanoulinou, S.; Riccio, O.; Zanoletti, O.; Guillot de Suduiraut, I.; Grosse, J.; Sandi, C.
Published in Neuropsychopharmacology in 2019

Diazepam actions in the VTA enhance social dominance and mitochondrial function in the nucleus accumbens by activation of dopamine D1 receptors

Van Der Kooij, M.A.; Hollis, F.; Lozano, L.; Zalachoras, I.; Abad, S.; Zanoletti, O.; Grosse, J.; Guillot De Suduiraut, I.; Canto, C.; Sandi, C
Published in Molecular Psychiatry in 2018

Increased brain glucocorticoid actions following social defeat in rats facilitates the long-term establishment of social subordination

Weger, M.; Sevelinges, Y.; Grosse, J.; de Suduiraut, I.G.; Zanoletti, O.; Sandi, C
Published in Physiology and Behavior in 2018

Peripubertal stress increases play fighting at adolescence and modulates nucleus accumbens CB1 receptor expression and mitochondrial function in the amygdala

Hollis, F.; Sevelinges, Y.; Grosse, J.; Zanoletti, O.; Sandi, C
Published in Eneuro in 2016

Involvement of CRFR1 in the basolateral amygdala in the immediate fear extinction deficit

Hollis, F.; Sevelinges, Y.; Grosse, J.; Zanoletti, O.; Sandi, C.
Published in eNeuro in 2016

Neuroligin-2 Expression in the Prefrontal Cortex is Involved in Attention Deficits Induced by Peripubertal Stress

Tzanoulinou, S.; García-Mompó, C.; Riccio, O.; Grosse, J.; Zanoletti, O.; Dedousis, P.; Nacher, J.; Sandi, C.
Published in Neuropsychopharmacology in 2016

Hippocampal neuroligin-2 links early-life stress with impaired social recognition and increased aggression in adult mice

Kohl, C.; Wang, X.-D.; Grosse, J.; Fournier, C.; Harbich, D.; Westerholz, S.; Li, J.-T.; Bacq, A.; Sippel, C.; Hausch, F, Sandi, C.
Published in Psychoneuroendocrinology in 2015

The effects of stress during early postnatal periods on behavior and hippocampal neuroplasticity markers in adult male mice

van der Kooij, M.A.; Grosse, J.; Zanoletti, O.; Papilloud, A.; Sandi, C.
Published in Neuroscience in 2015

Impaired hippocampal neuroligin-2 function by chronic stress or synthetic peptide treatment is linked to social deficits and increased aggression

JVan Der Kooij, M.A.; Fantin, M.; Kraev, I.; Korshunova, I.; Grosse, J.; Zanoletti, O.; Guirado, R.; Garcia-Mompó, C.; Nacher, J.; Stewart, M.G.; Sandi C.
Published in Neuropsychopharmacology in 2014

Role for MMP-9 in stress-induced downregulation of nectin-3 in hippocampal CA1 and associated behavioural alterations

Van Der Kooij, M.A.; Fantin, M.; Rejmak, E.; Grosse, J.; Zanoletti, O.; Fournier, C.; Ganguly, K.; Kalita, K.; Kaczmarek, L.; Sandi, C
Published in Nature Communications in 2014

A Key Role for Nectin-1 in the Ventral Hippocampus in Contextual Fear Memory

Fantin, M.; van der Kooij, M.A.; Grosse, J.; Krummenacher, C.; Sandi, C
Published in Plos One in 2014

Hippocampal Neuroligin-2 Overexpression Leads to Reduced Aggression and Inhibited Novelty Reactivity in Rats

Kohl, C.; Riccio, O.; Grosse, J.; Zanoletti, O.; Fournier, C.; Schmidt, M.V.; Sandi, C
Published in Plos One in 2013

The interplay of conditional NCAM-knockout and chronic unpredictable stress leads to increased aggression in mice

Kohl, C.; Riccio, O.; Grosse, J.; Zanoletti, O.; Fournier, C.; Klampfl, S.M.; Schmidt, M.V.; Sandi, C.
Published in Stress in 2013