Juan Cruz Landoni
Web site: Web site: https://leb.epfl.ch
Web site: Web site: https://sb.epfl.ch/conseil
Fields of expertise
Research interest
I am a chemist turned mitochondria enthusiast. Using molecular biology and "smart" super-resolution imaging techniques, I am exploring the complex behavior of the tiny cellular intruders called mitochondria, and how this affects their genetics, function, and the health of the cell as a whole.Professional course
Postdoctoral Fellow
Laboratory of Experimental Biophysics | Manley Lab
Institute of Physics, EPFL
July 2022 - present
Research Facilitator
Physiology: Modern Cell Biology Using Microscopic, Biochemical and Computational Approaches
Marine Biological Laboratory (MBL) - Woods Hole MA
June - July 2024
Doctoral Researcher
Mitochondrial Medicine | Suomalainen-Wartiovaara Lab
Stem Cells & Metabolism, University of Helsinki
January 2019 - July 2022
Undergraduate/Master’s student
Mitochondrial Medicine | Suomalainen-Wartiovaara Lab
Molecular Neurology, University of Helsinki
January 2014 - January 2019
Editor in chief
MyScience magazine
LUMA Education Centre Finland
January 2015 - January 2017
Education
Doctor of Philosophy (Ph.D.)
Integrative Life Sciences
Faculty of Medicine, University of Helsinki
July 2022
Master of Science (M.Sc.)
Translational Medicine
Faculty of Medicine, University of Helsinki
January 2019
Bachelor of Science (B.Sc.)
Chemistry
Faculty of Science, University of Helsinki
February 2017
Publications
Selected publications
| Landoni, et al. bioRxiv |
Overactive mitochondrial DNA replisome causes neonatal heart failure via ferroptosis |
| Kuukasjärvi*, Landoni*, et al. European Journal of Human Genetics |
IMPDH2: a new gene associated with dominant juvenile-onset dystonia-tremor disorder |
| Hämäläinen, Landoni*, et al. Nature Metabolism |
Defects in mtDNA replication challenge nuclear genome stability through nucleotide depletion and provide a unifying mechanism for mouse progerias |
| Landoni, Wang & Suomalainen. Biology Methods and Protocols |
Quantitative solid-phase assay to measure deoxynucleoside triphosphate pools |
| Nikkanen, Landoni, et al. EMBO molecular medicine |
A complex genomic locus drives mt DNA replicase POLG expression to its disease‐related nervous system regions |
| Juan C Landoni, Tatjana Kleele, Julius Winter, Willi Stepp, Suliana Manley Annual Review of Cell and Developmental Biology |
Mitochondrial Structure, Dynamics, and Physiology: Light Microscopy to Disentangle the Network |