Julie Parchet-Piccand
julie.parchet-piccand@epfl.ch +41 21 693 73 42 https://inside.epfl.ch/https://www.epfl.ch/research/facilities/cpg/
EPFL SV CPG-GE
SV 1841 (Bâtiment SV)
Station 19
1015 Lausanne
+41 21 693 73 42
Office: SV 1841
EPFL › SV › CPG › CPG-GE
Site web: https://cpg.epfl.ch/
Expertise
Developmental Biology (Endocrine cells of the pancreas and intestine)
Metabolism
Humanised Liver/Pancreas mice
Mission
Travail en cours
Formation
PhD
| Biologie du Développement et cellules souches
2008 – 2012
Université de Strasbourg
Dirigée par
Gérard Gradwohl - IGBMC
Ingénieur EPF / Master
| Biologie cellulaire et oncologie moléculaire2006 – 2008 Ecole Polytechnique Fédérale de Lausanne
Bachelor
| Neuroscience2003 – 2006 Ecole Polytechnique Fédérale de Lausanne
Expériences professionnelles
Manager scientifique de projet / Post-Doc
Participation au projet financé par le FP7 Health and the Understanding of Metabolism, Aging and Nutrition.
Préparation des dossiers pour l’autorisation éthique en lien avec la Loi relative à la recherche sur l’être humain.
Spécialiste associée / Post-Doc
Participation au projet financé par le FP7 Health and the Understanding of Metabolism, Aging and Nutrition.
Post-Doc
Caractérisation du métabolisme endocrinien.
Etudiante en thèse
Stagière
Etudiante de Master
Prix et distinctions
Swiss 3R Competence Centre
2022
Publications représentatives
Mice with humanized livers reveal the role of hepatocyte clocks in rhythmic behavior.
AS Delbès, M Quinones, C Gobet, J Castel, R Denis, J Berthelet, BD Weger, E Challet, A Charpagne, S Metairon, J Piccand, M Kraus, BH Rohde, J Bial, EM Wilson, LL Vedin, ME Minniti, M Pederelli, P Parini, F Gachon and S Luquet
Published in Science Advances in 2023
Rfx6 promotes the differentiation of peptide-secreting enteroendocrine cells while repressing genetic programs controlling serotonin production
Piccand J*, Vagne C*, Blot F*, Meunier A, Beucher A, Strasser P, Lund ML, Ghimire S, Nivlet L, Lapp C, Petersen N, Engelstoft MS, Thibault-Carpentier C, Keime C, JimenezCorrea S, Schreiber V, Molina N, Schwartz TW, Gradwohl G
Published in Molecular Metabolism in 2019
Applying hydrodynamic pressure to efficiently generate induced pluripotent stem cells via reprogramming of centenarian skin fibroblasts.
Vosough M, Ravaioli F, Zabulica M, Capri M, Garagnani P, Franceschi C, Piccand J, Kraus MR, Kannisto K, Gramignoli R, Strom SC
Published in PLoS One in 2019
Macroencapsulated Human iPSC-Derived Pancreatic Progenitors Protect against STZ-Induced Hyperglycemia in Mice.
Haller C*, Piccand J*, De Franceschi F, Ohi Y, Bhoumik A, Boss C, De Marchi U, Jacot G, Metairon S, Descombes P, Wiederkehr A, Palini A, Bouche N, Steiner P, Kelly OG, R-C Kraus M
Published in Stem Cell Reports in 2019
Insights into Islet Differentiation and Maturation through Proteomic Characterization of a Human iPSC-Derived Pancreatic Endocrine Model
Haller C*, Chaskar P*, Piccand J, Cominetti O, Macron C, Dayon L, Kraus MR
Published in Proteomics Clinical Applications in 2018
RFX6 regulates insulin secretion by modulating Ca2 homeostasis in human beta-ells
Chandra V, Albagli-Curiel O, Hastoy B, Piccand J, Randriamampita C, Vaillant E, Cavé, H, Busiah K, Froguel P, Vaxillaire M, Rorsman P, Polak M, Scharfmann R
Published in Cell Reports in 2014
Rfx6 maintains the functional identity of adult pancreatic beta-cells
Piccand J, Strasser P, Hodson DJ, Meunier A, Ye T, Keime C, Birling MC, Rutter GA, Gradwohl G.
Published in Cell Reports in 2014
Pak3 promotes cell cycle exit and differentiation of β-cells in the embryonic pancreas and is necessary to maintain glucose homeostasis in adult mice
Piccand J, Meunier A, Merle C, Jia Z, Barnier JV, Gradwohl G
Published in Diabetes in 2013