Julie Parchet

Elle - She/her

EPFL SV CPG-GE
SV 1841 (Bâtiment SV)
Station 19
1015 Lausanne

Mission

The Center of PhenoGenomics is specialised in animal experimentation and alternatives. We contribute to the research excellence by supporting the scientific community through tailored services and advice.

Through our commitment, professionalism and strong team spirit, we work altogether to ensure the welfare of laboratory animals in compliance with laws and ethics.

Current Work

Animal Welfare Officer at the Center of PhenoGenomics

Education

PhD

| Developmental Biology and Stem Cell Programme

2008 – 2012 Université de Strasbourg
Directed by Gérard Gradwohl - IGBMC

Ingénieur EPF / Master

| Cell Biology and Molecular Oncology

2006 – 2008 Ecole Polytechnique Fédérale de Lausanne

Bachelor

| Neurosciences

2003 – 2006 Ecole Polytechnique Fédérale de Lausanne

Professionals experiences

Scientific Project Manager / Post-Doc

Differentiation of iPSC into pancreatic progenitors and characterisation of liver humanised mice.
Part of the Health and the Understanding of Metabolism, Aging and Nutrition FP7 founded project.
Preparation of files for ethical approval related to the Human Research Act.

Associate Specialist /Post-Doc

Differentiation of iPSC into pancreatic progenitors and characterisation of liver humanised mice.
Part of the Health and the Understanding of Metabolism, Aging and Nutrition FP7 founded project.

Post-doctoral Fellow

Control of endocrine cell differentiation in the pancreas and intestine.
Understanding of endocrine metabolism.

PhD Student

Control of endocrine cell differentiation in the pancreas and intestine.

Intern

Study of the genetic components of pre-eclampsia

Master Student

Studied the role of BMPs on pancreas development and cancer

Awards

Culture of Care Award

Swiss 3R Competence Centre

2022

Selected publications

Mice with humanized livers reveal the role of hepatocyte clocks in rhythmic behavior.

AS Delbès, M Quinones, C Gobet, J Castel, R Denis, J Berthelet, BD Weger, E Challet, A Charpagne, S Metairon, J Piccand, M Kraus, BH Rohde, J Bial, EM Wilson, LL Vedin, ME Minniti, M Pederelli, P Parini, F Gachon and S Luquet
Published in Science Advances in 2023

Rfx6 promotes the differentiation of peptide-secreting enteroendocrine cells while repressing genetic programs controlling serotonin production

Piccand J*, Vagne C*, Blot F*, Meunier A, Beucher A, Strasser P, Lund ML, Ghimire S, Nivlet L, Lapp C, Petersen N, Engelstoft MS, Thibault-Carpentier C, Keime C, JimenezCorrea S, Schreiber V, Molina N, Schwartz TW, Gradwohl G
Published in Molecular Metabolism in 2019

Applying hydrodynamic pressure to efficiently generate induced pluripotent stem cells via reprogramming of centenarian skin fibroblasts.

Vosough M, Ravaioli F, Zabulica M, Capri M, Garagnani P, Franceschi C, Piccand J, Kraus MR, Kannisto K, Gramignoli R, Strom SC
Published in PLoS One in 2019

Macroencapsulated Human iPSC-Derived Pancreatic Progenitors Protect against STZ-Induced Hyperglycemia in Mice.

Haller C*, Piccand J*, De Franceschi F, Ohi Y, Bhoumik A, Boss C, De Marchi U, Jacot G, Metairon S, Descombes P, Wiederkehr A, Palini A, Bouche N, Steiner P, Kelly OG, R-C Kraus M
Published in Stem Cell Reports in 2019

Insights into Islet Differentiation and Maturation through Proteomic Characterization of a Human iPSC-Derived Pancreatic Endocrine Model

Haller C*, Chaskar P*, Piccand J, Cominetti O, Macron C, Dayon L, Kraus MR
Published in Proteomics Clinical Applications in 2018

RFX6 regulates insulin secretion by modulating Ca2 homeostasis in human beta-ells

Chandra V, Albagli-Curiel O, Hastoy B, Piccand J, Randriamampita C, Vaillant E, Cavé, H, Busiah K, Froguel P, Vaxillaire M, Rorsman P, Polak M, Scharfmann R
Published in Cell Reports in 2014

Rfx6 maintains the functional identity of adult pancreatic beta-cells

Piccand J, Strasser P, Hodson DJ, Meunier A, Ye T, Keime C, Birling MC, Rutter GA, Gradwohl G.
Published in Cell Reports in 2014

EPFL Publications

Mice with humanized livers reveal the role of hepatocyte clocks in rhythmic behavior

A.-S. DelbesM. QuinonesC. GobetJ. CastelR. G. P. Denis  et al.

Science Advances. 2023-05-19. DOI : 10.1126/sciadv.adf2982.

Role of BMP signalling in the developing pancreas

J. Piccand

2008

La transsexualité en Thaïlande

J. PiccandS. MoretC. Fellay

2007