Li Tang
EPFL STI IBI-STI LBI
MED 1 2826 (Bâtiment MED)
Station 9
1015 Lausanne
+41 21 693 07 56
+41 21 693 09 37
Office: MED 1 2826
EPFL › STI › IBI-STI › LBI
Website: https://tang-lab.epfl.ch/
EPFL STI IMX-GE
MED 1 2826 (Bâtiment MED)
Station 9
1015 Lausanne
+41 21 693 09 37
Office: MED 1 2826
EPFL › STI › IMX › IMX-GE
+41 21 693 09 37
EPFL › STI › STI-SMX › SMX-ENS
+41 21 693 09 37
EPFL › SV › SV-SSV › SSV-ENS
Website: https://sv.epfl.ch/education
+41 21 693 09 37
EPFL › VPA › VPA-AVP-DLE › AVP-DLE-EDOC › EDMS-ENS
Website: https://go.epfl.ch/edms
+41 21 693 09 37
EPFL › VPA › VPA-AVP-DLE › AVP-DLE-EDOC › EDBB-GE
Website: https://go.epfl.ch/phd-edbb
+41 21 693 09 37
EPFL › SV › SV-DEC › SV-DIR
Expertise
Cancer immunotherapy
Immune metabolism
Mechano-immunology
Biomaterials
Mission
Professionals experiences
Assistant Professor
CRI Irvington Postdoctoral Fellow
Advisor: Darrell J. Irvine
Education
Materials Science and Engineering
| Urbana, IL, USA
2007 – 2012
University of Illinois at Urbana-Champaign (UIUC)
Directed by
Jianjun Cheng
Chemistry
| Beijing, China2003 – 2007 Peking University (PKU)
Awards
European Research Council (ERC) Consolidator Grant
European Research Council (ERC)
2025
Highly Cited Researcher in the field of Cross-Field
Web of Science
2025
Stanisław Lem European Research Prize (Lem Prize)
Wrocław Tech
2025
Friedrich Miescher Award
Life Sciences Switzerland (LS2)
2025
Biomaterials Science Lectureship
Biomaterials Science
2025
Leenaards Prize for Translational Medical Research
Leenaards Foundation
2025
Biomaterials Award for Young Investigators
Biomaterials
2024
MIT TR 35 Innovators Under 35 of China Region
MIT Technology Review
2020
European Research Council (ERC) Starting Grant
European Research Council
2018
Selected publications
The type 2 cytokine Fc–IL-4 revitalizes exhausted CD8 T cells against cancer
Published in Nature in 2024
Single-cell CAR T atlas reveals type2 function in 8-year leukemia remission
Published in Nature in 2024
IL-10-expressing, anti-CD19 CAR T cells for patients with relapsed or refractory B-cell acute lymphoblastic leukaemia: an open-label, single-arm, phase 1 study
Published in The Lancet Haematology in 2025
IL-10-expressing CAR T cells resist dysfunction and mediate durable clearance of solid tumors and metastases
Published in Nature Biotechnology in 2024
Metabolic reprogramming of terminally exhausted CD8 T cells by IL-10 enhances anti-tumor immunity
Published in Nature Immunology in 2021
Cancer-cell stiffening via cholesterol depletion enhances adoptive T-cell immunotherapy
Published in Nature Biomedical Engineering in 2021
Switchable immune modulator for tumor-specific activation of anticancer immunity
Published in Science Advances in 2021
Enhancing T cell therapy through TCR-signaling-responsive nanoparticle drug delivery
Published in Nature Biotechnology in 2018
Evidence and therapeutic implications of biomechanically regulated immunosurveillance in cancer and other diseases
Published in Nature Nanotechnology in 2024
Teaching & PhD
PhD Students
Rongrong Li, Nadia Yasmina Ben Sayed, Yunyi Zhou, Yann Tinguely, Weilin Li, Tom Enbar
Past EPFL PhD Students
Yuqing Xie, Kewen Lei, Yang Zhao, Min Gao, Xiaomeng Hu, Armand Kurum, Lucia Bonati
Past EPFL PhD Students as codirector
Lixia Wei, Céline Jasmin Prange
Courses
Concept to early-stage drug and medTech products
BIO-497
This course explores how innovative drugs and medical devices are brought to the market. Experts from leading companies share real-world insights and experiences. By the end, students gain a clear and practical understanding of the clinical, regulatory and quality aspects.
Immunoengineering
BIOENG-399
Immunoengineering is an emerging field where engineering principles are grounded in immunology. This course provides students a broad overview of how engineering approaches can be utilized to study immunology, model immune systems, modulate immune response, and develop novel immunotherapies.
Next-generation biomaterials
BIOENG-458
"Next-Generation Biomaterials" explores the latest advancements in the development and application of cutting-edge biomaterials for medical and healthcare innovation.
Practical - Tang Lab
BIO-603(TL)
In this course, the students will learn the basics skills in cancer immunotherapy and immunoengineering. Open to 4 students.