Loïc Dayon
EPFL › SB › SB-SCGC › SCGC-ENS
Site web: https://www.epfl.ch/schools/sb/scgc/
Publications représentatives
Probing cysteine reactivity in proteins by mass spectrometric EC-tagging
Dayon L., Roussel C., Girault H.H.
Published in J. Proteome Res. 2006, 5, 793-800 in
Electrochemical multi-tagging of cysteinyl peptides during microspray mass spectrometry: numerical simulation of consecutive reactions in a microchannel
Dayon L., Josserand J., Girault H.H.
Published in Phys. Chem. Chem. Phys. 2005, 7, 4054-4060 in
On-line counting of cysteine residues in peptides during electrospray ionization by electrogenerated tags and their application to protein identification
Dayon L., Roussel C., Prudent M., Lion N., Girault H.H.
Published in Electrophoresis 2005, 26, 238-247 in
Generation of mass tags by the inherent electrochemistry of electrospray for protein mass spectrometry
Roussel C., Dayon L., Lion N., Rohner T.C., Josserand J., Rossier J.S:, Jensen H., Girault H.H.
Published in J. Am. Soc. Mass Spectrom. 2004, 15, 1767-1779 in
On-line cysteine modification for protein analysis: new probes for electrochemical tagging nanospray mass spectrometry
Roussel C., Dayon L., Jensen H., Girault H. H.
Published in J. Electroanal. Chem. 2004, 570, 187-199
in
On-line electrochemical tagging of free cysteines in peptides during nanospray ionisation mass spectrometry: An overview
Dayon L., Roussel C., Girault H.H.
Published in Chimia 2004, 58, 204-207 in
Microfluidic systems in proteomics
Lion N., Rohner T.C., Dayon L., Arnaud I.L., Damoc E., Youhnovski N., Wu Z., Roussel C., Josserand J., Jensen H., Rossier J.S., Przybylski M., Girault H.H.
Published in Electrophoresis 2003, 24, 3533-3562 in
MAIN PUBLICATIONS
SLC25A46 promotes mitochondrial fission and mediates resistance to lipotoxic stress in INS-1E insulin-secreting cells
Journal Of Cell Science. 2023-04-01. DOI : 10.1242/jcs.260049.The promise of multi-omics approaches to discover biological alterations with clinical relevance in Alzheimer's disease
Frontiers In Aging Neuroscience. 2022-12-07. DOI : 10.3389/fnagi.2022.1065904.Blood plasma protein profiles of neuropsychiatric symptoms and related cognitive decline in older people
Journal Of Neurochemistry. 2022-11-15. DOI : 10.1111/jnc.15715.Proteomics reveals unique plasma signatures in constitutional thinness
Proteomics Clinical Applications. 2022-05-26. DOI : 10.1002/prca.202100114.Systemic and central nervous system neuroinflammatory signatures of neuropsychiatric symptoms and related cognitive decline in older people
Journal Of Neuroinflammation. 2022-05-28. DOI : 10.1186/s12974-022-02473-3.Proteomics of human biological fluids for biomarker discoveries: technical advances and recent applications
Expert Review Of Proteomics. 2022-05-06. DOI : 10.1080/14789450.2022.2070477.Assessing normalization methods in mass spectrometry-based proteome profiling of clinical samples
Biosystems. 2022-06-01. DOI : 10.1016/j.biosystems.2022.104661.Cerebrospinal Fluid Proteome Alterations Associated with Neuropsychiatric Symptoms in Cognitive Decline and Alzheimer's Disease
Cells. 2022-03-01. DOI : 10.3390/cells11061030.Crosstalk between Drp1 phosphorylation sites during mitochondrial remodeling and their impact on metabolic adaptation
Cell Reports. 2021-08-24. DOI : 10.1016/j.celrep.2021.109565.Proteomics of Human Milk: Definition of a Discovery Workflow for Clinical Research Studies
Journal Of Proteome Research. 2021-05-07. DOI : 10.1021/acs.jproteome.0c00816.An integrative multi-omics approach reveals new central nervous system pathway alterations in Alzheimer's disease
Alzheimers Research & Therapy. 2021-04-01. DOI : 10.1186/s13195-021-00814-7.Augmented mitochondrial energy metabolism is an early response to chronic glucose stress in human pancreatic beta cells
Diabetologia. 2020-09-22. DOI : 10.1007/s00125-020-05275-5.Exploration of human cerebrospinal fluid: A large proteome dataset revealed by trapped ion mobility time-of-flight mass spectrometry
Data In Brief. 2020-08-01. DOI : 10.1016/j.dib.2020.105704.Progress and pitfalls of using isobaric mass tags for proteome profiling
Expert Review Of Proteomics. 2020-02-23. DOI : 10.1080/14789450.2020.1731309.Novel Analytical Methods for Allergy-Related Studies
Lausanne, EPFL, 2020. DOI : 10.5075/epfl-thesis-7271.Mass Spectrometry Methods for Bacterial Infection Diagnosis and Cancer Analysis
Lausanne, EPFL, 2019. DOI : 10.5075/epfl-thesis-9322.Circadian and Feeding Rhythms Orchestrate the Diurnal Liver Acetylome
Cell Reports. 2017. DOI : 10.1016/j.celrep.2017.07.065.Nuclear Proteomics Uncovers Diurnal Regulatory Landscapes in Mouse Liver
Cell Metabolism. 2017. DOI : 10.1016/j.cmet.2016.10.003.Proteomics of Cerebrospinal Fluid: Throughput and Robustness Using a Scalable Automated Analysis Pipeline for Biomarker Discovery
Analytical Chemistry. 2015. DOI : 10.1021/acs.analchem.5b02748.Proteomics and circadian rhythms: It's all about signaling!
Proteomics. 2015. DOI : 10.1002/pmic.201400187.Comprehensive and Scalable Highly Automated MS-Based Proteomic Workflow for Clinical Biomarker Discovery in Human Plasma
Journal Of Proteome Research. 2014. DOI : 10.1021/pr500635f.From allergen detection to protein-ligand interactions
Lausanne, EPFL, 2014. DOI : 10.5075/epfl-thesis-6332.Combination of Gas-Phase Fractionation and MS3 Acquisition Modes for Relative Protein Quantification with Isobaric Tagging
Journal Of Proteome Research. 2012. DOI : 10.1021/pr300519c.Electrospray Micromixer Chip for On-Line Derivatization and Kinetic Studies
Analytical Chemistry. 2008. DOI : 10.1021/ac800058h.Diagonal chromatographic selection of cysteinyl peptides modified with benzoquinones
Analytical and Bioanalytical Chemistry. 2007. DOI : 10.1007/s00216-007-1492-8.Multitrack electrospray chips
Journal of Mass Spectrometry. 2006. DOI : 10.1002/jms.1119.Probing Cysteine Reactivity in Proteins by Mass Spectrometric EC-Tagging
Journal of Proteome Research. 2006. DOI : 10.1021/pr050365o.Thiol-targeted microspray mass spectrometry of peptides and proteins through on-line EC-tagging
Lausanne, EPFL, 2006. DOI : 10.5075/epfl-thesis-3525.Electrochemical Multi-Tagging of Cysteinyl Peptides during Microspray Mass Spectrometry: Numerical Simulation of Consecutive Reactions in a Microchannel
Phys. Chem. Chem. Phys. 2005. DOI : 10.1039/b511334b.On-Line Counting of Cysteine Residues in Peptides during Electrospray Ionization by Electrogenerated Tags and Their Application to Protein Identification
Electrophoresis. 2005. DOI : 10.1002/elps.200406144.On-Line Electrochemical Tagging of Free Cysteines in Peptides during Nanospray Ionisation Mass Spectroscopy: An Overview
Chimia. 2004. DOI : 10.2533/000942904777678028.On-line cysteine modification for protein analysis: new probes for electrochemical tagging nanospray mass spectrometry
Journal of Electroanalytical Chemistry. 2004. DOI : 10.1016/j.jelechem.2004.03.029.Generation of Mass Tags by the Inherent Electrochemistry of Electrospray for Protein Mass Spectrometry
Journal of the American Society for Mass Spectrometry. 2004. DOI : 10.1016/j.jasms.2004.08.006.Microfluidic systems in proteomics
Electrophoresis. 2003. DOI : 10.1002/elps.200305629.Enseignement et PhD
Courses
Protein mass spectrometry and proteomics
CH-419
L'analyse protéomique est un pilier essentiel de la biologie des systèmes, permettant une meilleure compréhension du vivant. Les technologies protéomiques, et en particulier celles basées sur la spectrométrie de masse, permettent désormais de cartographier les protéomes à large échelle.