online people directory

Using integrative structural biology for the identification of novel aerolysin-like pore forming toxins for nanopore sensing

J. S. Anton; F. Meireles; J. F. Bada; M. J. Marcaida; M. Dal Peraro

2023-07-01. p. S116-S116.

Structure and dynamics of Toll immunoreceptor activation in the mosquito Aedes aegypti

Y. Saucereau; T. H. Wilson; M. C. K. Tang; M. C. Moncrieffe; S. W. Hardwick et al.

Nature Communications. 2022-08-30. DOI : 10.1038/s41467-022-32690-6.

Prolyl endopeptidase-like is a (thio)esterase involved in mitochondrial respiratory chain function

K. Rosier; M. T. McDevitt; J. Smet; B. J. Floyd; M. Verschoore et al.

Iscience. 2021-12-17. DOI : 10.1016/j.isci.2021.103460.

Palmitoylated acyl protein thioesterase APT2 deforms membranes to extract substrate acyl chains

L. Abrami; M. Audagnotto; S. Ho; M. J. Marcaida; F. S. Mesquita et al.

Nature Chemical Biology. 2021-04-01. DOI : 10.1038/s41589-021-00753-2.

The Human RNA Helicase DDX21 Presents a Dimerization Interface Necessary for Helicase Activity

M. J. Marcaida Lopez; A. Kauzlaric; A. Duperrex; J. Sülzle; M. C. Moncrieffe et al.

iScience. 2020-11-18. DOI : 10.1016/j.isci.2020.101811.

The Polyglutamine Expansion at the N-Terminal of Huntingtin Protein Modulates the Dynamic Configuration and Phosphorylation of the C-Terminal HEAT Domain

T. Jung; B. Shin; G. Tamo; H. Kim; R. Vijayvargia et al.

Structure. 2020-09-01. DOI : 10.1016/j.str.2020.06.008.

Btk SH2-kinase interface is critical for allosteric kinase activation and its targeting inhibits B-cell neoplasms

D. P. Duarte; A. J. Lamontanara; G. La Sala; S. Jeong; Y.-K. Sohn et al.

Nature Communications. 2020-05-08. DOI : 10.1038/s41467-020-16128-5.

Structural and functional divergence of duplicated mosquito Toll and Spz compared to Drosophila

Y. Saucereau; M. J. Marcaida; M. Gangloff

2020-05-01. Annual Meeting of the American-Association-of-Immunologists - Immunology 2020, Honolulu, HI, May 08-12, 2020.

Single-molecule sensing of peptides and nucleic acids by engineered aerolysin nanopores

C. Cao; N. Cirauqui; M. J. Marcaida; E. Buglakova; A. Duperrex et al.

Nature Communications. 2019-10-29. DOI : 10.1038/s41467-019-12690-9.

KAP1 is an antiparallel dimer with a functional asymmetry

G. Fonti; M. J. Marcaida; L. C. Bryan; S. Traeger; A. S. Kalantzi et al.

Life Science Alliance. 2019-08-01. DOI : 10.26508/lsa.201900349.

Structure and dynamics of mesophilic variants from the homing endonuclease I-DmoI

J. Alba; M. J. Marcaida; J. Prieto; G. Montoya; R. Molina et al.

Journal Of Computer-Aided Molecular Design. 2017. DOI : 10.1007/s10822-017-0087-5.

Key Players in I-DmoI Endonuclease Catalysis Revealed from Structure and Dynamics

R. Molina; N. Besker; M. J. Marcaida; G. Montoya; J. Prieto et al.

ACS chemical biology. 2016. DOI : 10.1021/acschembio.5b00730.

Discovery of a Selective Aurora A Kinase Inhibitor by Virtual Screening

F. Kilchmann; M. J. Marcaida; S. Kotak; T. Schick; S. D. Boss et al.

Journal Of Medicinal Chemistry. 2016. DOI : 10.1021/acs.jmedchem.6b00709.

X-ray structure of a lectin-bound DNA duplex containing an unnatural phenanthrenyl pair

P. Roethlisberger; A. Istrate; M. J. M. Lopez; R. Visini; A. Stocker et al.

Chemical Communications. 2016. DOI : 10.1039/c6cc00374e.

Engineering a Nickase on the Homing Endonuclease I-DmoI Scaffold

R. Molina; M. J. Marcaida; P. Redondo; M. Marenchino; P. Duchateau et al.

The Journal of biological chemistry. 2015. DOI : 10.1074/jbc.M115.658666.

Bridged bicyclic peptides as potential drug scaffolds: synthesis, structure, protein binding and stability

M. Bartoloni; X. Jin; M. J. Marcaida; J. Banha; I. Dibonaventura et al.

Chemical Science. 2015. DOI : 10.1039/c5sc01699a.

Structural insights on cholesterol endosynthesis: Binding of squalene and 2,3-oxidosqualene to supernatant protein factor

M. Christen; M. J. Marcaida; C. Lamprakis; W. Aeschimann; J. Vaithilingam et al.

Journal Of Structural Biology. 2015. DOI : 10.1016/j.jsb.2015.05.001.

Oxypurinol directly and immediately activates the drug-specific T cells via the preferential use of HLA-B*58:01

J. Yun; M. J. Marcaida; K. K. Eriksson; H. Jamin; S. Fontana et al.

Journal of immunology (Baltimore, Md. : 1950). 2014. DOI : 10.4049/jimmunol.1302306.

Visualizing phosphodiester-bond hydrolysis by an endonuclease

R. Molina; S. Stella; P. Redondo; H. Gomez; M. J. Marcaida et al.

Nature structural & molecular biology. 2014. DOI : 10.1038/nsmb.2932.

Solution structure of human growth arrest and DNA damage 45alpha (Gadd45alpha) and its interactions with proliferating cell nuclear antigen (PCNA) and Aurora A kinase

R. Sánchez; D. Pantoja-Uceda; J. Prieto; T. Diercks; M. J. Marcaida et al.

The Journal of biological chemistry. 2010. DOI : 10.1074/jbc.M109.069344.

Homing endonucleases: from basics to therapeutic applications

M. J. Marcaida; I. G. Muñoz; F. J. Blanco; J. Prieto; G. Montoya

Cellular and molecular life sciences : CMLS. 2009. DOI : 10.1007/s00018-009-0188-y.

Molecular basis of histone H3K4me3 recognition by ING4

A. Palacios; I. G. Muñoz; D. Pantoja-Uceda; M. J. Marcaida; D. Torres et al.

The Journal of biological chemistry. 2008. DOI : 10.1074/jbc.M710020200.

Complementing structural information of modular proteins with small angle neutron scattering and contrast variation

J. G. Grossmann; A. J. Callaghan; M. J. Marcaida; B. F. Luisi; F. H. Alcock et al.

European biophysics journal : EBJ. 2008. DOI : 10.1007/s00249-008-0278-z.

The crystal structure of the Escherichia coli RNase E apoprotein and a mechanism for RNA degradation

D. J. Koslover; A. J. Callaghan; M. J. Marcaida; E. F. Garman; M. Martick et al.

Structure. 2008. DOI : 10.1016/j.str.2008.04.017.

Crystal structure of I-DmoI in complex with its target DNA provides new insights into meganuclease engineering

M. J. Marcaida; J. Prieto; P. Redondo; A. D. Nadra; A. Alibés et al.

Proceedings of the National Academy of Sciences of the United States of America. 2008. DOI : 10.1073/pnas.0804795105.

Modulation of heme redox potential in the cytochrome c6 family

J. A. R. Worrall; B. G. Schlarb-Ridley; T. Reda; M. J. Marcaida; R. J. Moorlen et al.

Journal of the American Chemical Society. 2007. DOI : 10.1021/ja072346g.

The RNA degradosome: life in the fast lane of adaptive molecular evolution

M. J. Marcaida; M. A. DePristo; V. Chandran; A. J. Carpousis; B. F. Luisi

Trends in biochemical sciences. 2006. DOI : 10.1016/j.tibs.2006.05.005.

Structure of cytochrome c6A, a novel dithio-cytochrome of Arabidopsis thaliana, and its reactivity with plastocyanin: implications for function

M. J. Marcaida; B. G. Schlarb-Ridley; J. A. R. Worrall; J. Wastl; T. J. Evans et al.

Journal of molecular biology. 2006. DOI : 10.1016/j.jmb.2006.05.065.

Structure of Escherichia coli RNase E catalytic domain and implications for RNA turnover

A. J. Callaghan; M. J. Marcaida; J. A. Stead; K. J. McDowall; W. G. Scott et al.

Nature. 2005. DOI : 10.1038/nature04084.