Martinus Gijs
Full Professor
EPFL STI IMT LMIS2
BM 3128 (Bâtiment BM)
Station 17
CH-1015 Lausanne
+41 21 693 67 34
+41 21 693 77 31
Office:
BM 3128
EPFL
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STI
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IEM
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LMIS2
Web site: Web site: https://lmis2.epfl.ch/
+41 21 693 67 34
Office:
BM 3128
EPFL
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VPA
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VPA-AVP-PGE
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AVP-PGE-EDOC
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EDMI-ENS
Fields of expertise
Microsystems Microfluidics Bio-MEMS Magnetic Applications Microfabrication technologies
Mission
The Laboratory of Microsystems 2 of Prof. Martin Gijs was established in 1997 and has as mission the development of new microfabrication technologies and to exploit these for applications of industrial interest. We actively participate in national and international research programs. The research of LMIS2 is centered on four themes: - Novel microfabrication technologies - Magnetic applications - Microfluidics - Bio-Micro-Electro-Mechanical Systems (BioMEMS) Novel microfabrication technologies We have established a sol-gel process for the replication of three-dimensional and thin film glass nanostructures. Moreover, we have discovered a new sol-gel process to synthesize borosilicate nanoparticles. Magnetic applications We are working on miniaturised systems for the handling and magnetic transport of magnetic micro- and nanoparticles in microfluidic devices. Microfluidics Chemists and biologists have recognized the utility of microfabricated devices for transporting and manipulating liquids on a sub-?L scale. We are active in the realisation and use of glass and polymer microfluidic chips. BioMEMS We are developing microfluidic channel- and droplet-based microsystems for the handling of magnetic beads for biomedical and mixing applications. We demonstrated a variety of on-chip immuno- and cell-based- assays using magnetic beads in a microfluidic channel as substrate.Biography
Martin A.M. Gijs received his degree in physics in 1981 from the Katholieke Universiteit Leuven, Belgium and his Ph.D. degree in physics at the same university in 1986. He joined the Philips Research Laboratories in Eindhoven, The Netherlands, in 1987. Subsequently, he has worked there on micro-and nano-fabrication processes of high critical temperature superconducting Josephson and tunnel junctions, the microfabrication of microstructures in magnetic multilayers showing the giant magnetoresistance effect, the design and realisation of miniaturised motors for hard disk applications and the design and realisation of planar transformers for miniaturised power applications. He joined EPFL in 1997. His present interests are in developing technologies for novel magnetic devices, new microfabrication technologies for microsystems fabrication in general and the development and use of microsystems technologies for microfluidic and biomedical applications in particular.Publications
Infoscience publications
M. Gijs
Bubble-enhanced ultrasonic microfluidic chip for rapid DNA fragmentation (vol 22, pg 560, 2022)
Lab On A Chip. 2023-03-29. DOI : 10.1039/d3lc90037a.Efficient AC electrothermal flow (ACET) on-chip for enhanced immunoassays
Lab On A Chip. 2023-01-16. DOI : 10.1039/d2lc01147f.Multi-photon polymerization using upconversion nanoparticles for tunable feature-size printing
Nanophotonics. 2023-01-10. DOI : 10.1515/nanoph-2022-0598.Polydimethylsiloxane microstructure-induced acoustic streaming for enhanced ultrasonic DNA fragmentation on a microfluidic chip
Lab On A Chip. 2022-09-30. DOI : 10.1039/d2lc00366j.A central arctic extreme aerosol event triggered by a warm air-mass intrusion
Nature Communications. 2022-09-08. DOI : 10.1038/s41467-022-32872-2.The enhancement of DNA fragmentation in a bench top ultrasonic water bath with needle-induced air bubbles: Simulation and experimental investigation
Biomicrofluidics. 2022-07-01. DOI : 10.1063/5.0101740.Overview of the MOSAiC expedition: Snow and sea ice
Elementa-Science Of The Anthropocene. 2022-02-07. DOI : 10.1525/elementa.2021.000046.Overview of the MOSAiC expedition—Atmosphere
Elementa: Science of the Anthropocene. 2022-02-07. DOI : 10.1525/elementa.2021.00060.Selective attention involves a feature-specific sequential release from inhibitory gating
Neuroimage. 2022-02-01. DOI : 10.1016/j.neuroimage.2021.118782.Source imaging of high-density visual evoked potentials with multi-scale brain parcellations and connectomes
Scientific Data. 2022-01-19. DOI : 10.1038/s41597-021-01116-1.Bubble-enhanced ultrasonic microfluidic chip for rapid DNA fragmentation
Lab On A Chip. 2022-01-06. DOI : 10.1039/d1lc00933h.Piezoelectric suspended microchannel resonators
Lausanne, EPFL, 2022. DOI : 10.5075/epfl-thesis-9135.Microfluidic systems for in-flow bioanalytes collection
Lausanne, EPFL, 2022. DOI : 10.5075/epfl-thesis-8863.Ripening of two-dimensional colloidal CdSe nanocrystals into zero-dimensional nanodots
Iscience. 2021-12-17. DOI : 10.1016/j.isci.2021.103457.The connectome spectrum as a canonical basis for a sparse representation of fast brain activity
Neuroimage. 2021-12-01. DOI : 10.1016/j.neuroimage.2021.118611.Effect of inoculum size and antibiotics on bacterial traveling bands in a thin microchannel defined by optical adhesive
Microsystems & Nanoengineering. 2021-10-22. DOI : 10.1038/s41378-021-00309-3.Progress on the Upgrade of EDIPO, a 15 T Large Aperture Dipole
Ieee Transactions On Applied Superconductivity. 2021-08-01. DOI : 10.1109/TASC.2021.3061044.Antimicrobial susceptibility testing by measuring bacterial oxygen consumption on an integrated platform
Lab On A Chip. 2021-07-16. DOI : 10.1039/d1lc00296a.An In Vivo Microfluidic Study of Bacterial Load Dynamics and Absorption in the C. elegans Intestine
Micromachines. 2021-07-01. DOI : 10.3390/mi12070832.Phase calibration of a basic bright-field microscope for 3D metrology of transparent samples at the nanoscale
2021-01-01. Conference on Optics and Photonics for Advanced Dimensional Metrology, ELECTR NETWORK, Apr 06-10, 2020. p. 113521N. DOI : 10.1117/12.2559349.Microfluidic culture platforms for C. elegans bacterial interaction and digestion studies at single-organism resolution
Lausanne, EPFL, 2021. DOI : 10.5075/epfl-thesis-8598.Integration of polymeric membrane/dielectric sphere assemblies in microfluidic chips for enhanced-contrast imaging with low-magnification systems
Journal Of Optical Microsystems. 2021-01-01. DOI : 10.1117/1.JOM.1.1.014001.Towards an in vitro cardiac model: 3D environment, co-culture, alignment, and mechanical stimulation impact on cell behavior
Lausanne, EPFL, 2021. DOI : 10.5075/epfl-thesis-8434.Microfluidic Platforms for the Study of Bacterial Metabolism and Antimicrobial Susceptibility Testing
Lausanne, EPFL, 2021. DOI : 10.5075/epfl-thesis-8403.Insight into the Growth of Anisotropic CdSe Nanocrystals: Attachment of Intrinsically Different Building Blocks
Journal Of Physical Chemistry C. 2020-12-17. DOI : 10.1021/acs.jpcc.0c07933.Nested oscillations and brain connectivity during sequential stages of feature-based attention
Neuroimage. 2020-12-01. DOI : 10.1016/j.neuroimage.2020.117354.Connectome spectral analysis to track EEG task dynamics on a subsecond scale
Neuroimage. 2020-11-01. DOI : 10.1016/j.neuroimage.2020.117137.3D nanometrology of transparent objects by phase calibration of a basic bright-field microscope for multiple illumination apertures
Optics Express. 2020-09-14. DOI : 10.1364/OE.404240.Fast antimicrobial susceptibility testing onEscherichia coliby metabolic heat nanocalorimetry
Lab On A Chip. 2020-09-07. DOI : 10.1039/d0lc00579g.Anin vivomicrofluidic study of bacterial transit inC. elegansnematodes
Lab On A Chip. 2020-08-07. DOI : 10.1039/d0lc00064g.Magnetic and Mechanical 3-D Modelling of a 15 T Large Aperture Dipole Magnet
Ieee Transactions On Applied Superconductivity. 2020-06-01. DOI : 10.1109/TASC.2020.2969639.Force microscopy of the Caenorhabditis elegans embryonic eggshell
Microsystems & Nanoengineering. 2020-05-04. DOI : 10.1038/s41378-020-0137-3.Automated phenotyping of Caenorhabditis elegans embryos with a high-throughput-screening microfluidic platform
Microsystems & Nanoengineering. 2020-04-06. DOI : 10.1038/s41378-020-0132-8.PDMS filter structures for size-dependent larval sorting and on-chip egg extraction of C. elegans
Lab On A Chip. 2020-01-07. DOI : 10.1039/c9lc00949c.Microfluidic system for Caenorhabditis elegans culture and oxygen consumption rate measurements
Lab On A Chip. 2020-01-07. DOI : 10.1039/c9lc00829b.At the end of scaling: 2D materials for computing and sensing applications
Lausanne, EPFL, 2020. DOI : 10.5075/epfl-thesis-7695.The Detection of Early Epigenetic Inheritance of Mitochondrial Stress in C. Elegans with a Microfluidic Phenotyping Platform
Scientific Reports. 2019-12-17. DOI : 10.1038/s41598-019-55979-x.A power-balance model of the density limit in fusion plasmas: application to the L-mode tokamak
Nuclear Fusion. 2019-12-01. DOI : 10.1088/1741-4326/ab3b31.Rapid high-plex staining and simultaneous imaging for immunophenotyping of tissue sections
2019-11-06.Microfluidics-assisted multiplexed biomarker detection for in situ mapping of immune cells in tumor sections
Microsystems & Nanoengineering. 2019-11-06. DOI : 10.1038/s41378-019-0104-z.Overview of the JET preparation for deuterium-tritium operation with the ITER like-wall
Nuclear Fusion. 2019-11-01. DOI : 10.1088/1741-4326/ab2276.Automated Platform for Long-Term Culture and High-Content Phenotyping of Single C. elegans Worms
Scientific Reports. 2019-10-04. DOI : 10.1038/s41598-019-50920-8.Microfluidic-based immunohistochemistry for breast cancer diagnosis: a comparative clinical study
Virchows Archiv. 2019-09-01. DOI : 10.1007/s00428-019-02616-7.CMOS and 3D Printing for NMR Spectroscopy at the Single Embryo Scale
Chimia. 2019-08-01. DOI : 10.2533/chimia.2019.635.The 16 T Dipole Development Program for FCC and HE-LHC
IEEE Transactions on Applied Superconductivity. 2019-08-01. DOI : 10.1109/TASC.2019.2900556.EDGE2D-EIRENE simulations of the influence of isotope effects and anomalous transport coefficients on near scrape-off layer radial electric field
Plasma Physics And Controlled Fusion. 2019-07-01. DOI : 10.1088/1361-6587/ab1629.Geodesic acoustic mode evolution in L-mode approaching the L-H transition on JET
Plasma Physics And Controlled Fusion. 2019-07-01. DOI : 10.1088/1361-6587/ab1e73.Spontaneous Formation of CdSe Photoluminescent Nanotubes with Visible-Light Photocatalytic Performance
Acs Central Science. 2019-06-26. DOI : 10.1021/acscentsci.9b00184.On a fusion born triton effect in JET deuterium discharges with H-minority ion cyclotron range of frequencies heating
Nuclear Fusion. 2019-06-01. DOI : 10.1088/1741-4326/ab19f5.COREDIV numerical simulation of high neutron rate JET-ILW DD pulses in view of extension to JET-ILW DT experiments
Nuclear Fusion. 2019-05-01. DOI : 10.1088/1741-4326/ab0c47.Comparison of the structure of the plasma-facing surface and tritium accumulation in beryllium tiles from JET ILW campaigns 2011-2012 and 2013-2014
Nuclear Materials And Energy. 2019-05-01. DOI : 10.1016/j.nme.2019.02.011.First mirror test in JET for ITER: Complete overview after three ILW campaigns
Nuclear Materials And Energy. 2019-05-01. DOI : 10.1016/j.nme.2019.02.009.Radial variation of heat transport in L-mode JET discharges
Nuclear Fusion. 2019-05-01. DOI : 10.1088/1741-4326/ab03e1.Approximate analytic expressions using Stokes model for tokamak polarimetry and their range of validity
Plasma Physics And Controlled Fusion. 2019-05-01. DOI : 10.1088/1361-6587/ab09c2.Long-lived coupled peeling ballooning modes preceding ELMs on JET
Nuclear Fusion. 2019-05-01. DOI : 10.1088/1741-4326/ab0031.High-content, cell-by-cell assessment of HER2 overexpression and amplification: a tool for intratumoral heterogeneity detection in breast cancer
Laboratory Investigation. 2019-05-01. DOI : 10.1038/s41374-018-0172-y.Super-resolution optical imaging: A comparison
Micro And Nano Engineering. 2019-03-01. DOI : 10.1016/j.mne.2018.11.005.Combining fluorescence-based image segmentation and automated microfluidics for ultrafast cell-by-cell assessment of biomarkers for HER2-type breast carcinoma
Journal of Biomedical Optics. 2019-02-01. DOI : 10.1117/1.JBO.24.2.021204.Multimodal imaging and high-throughput image-processing for drug screening on living organisms on-chip
Journal of Biomedical Optics. 2019-02-01. DOI : 10.1117/1.JBO.24.2.021205.Automated high-content phenotyping from the first larval stage till the onset of adulthood of the nematode Caenorhabditis elegans
Lab On A Chip. 2019-01-07. DOI : 10.1039/c8lc00863a.Automated High-Content Phenotyping Of The Nematode C. Elegans At Single Animal Resolution With A Microfluidic Platform
2019-01-01. 20th International Conference on Solid-State Sensors, Actuators and Microsystems and Eurosensors XXXIII (TRANSDUCERS and EUROSENSORS), Berlin, GERMANY, Jun 23-27, 2019. p. 2209-2212. DOI : 10.1109/TRANSDUCERS.2019.8808300.Long-term imaging, automated high-content phenotyping and sorting of C. elegans larvae and embryos using microfluidic platforms
Lausanne, EPFL, 2019. DOI : 10.5075/epfl-thesis-7509.An assessment of nitrogen concentrations from spectroscopic measurements in the JET and ASDEX upgrade divertor
Nuclear Materials And Energy. 2019-01-01. DOI : 10.1016/j.nme.2018.12.012.Integration of microfluidics and multimodal optics for translational bioanalytics
Lausanne, EPFL, 2019. DOI : 10.5075/epfl-thesis-9546.Studying the roundworm Caenorhabditis elegans using microfluidic chips
2019-01-01. Conference on Microfluidics, BioMEMS, and Medical Microsystems XVII, San Francisco, CA, Feb 02-04, 2019. p. 1087518. DOI : 10.1117/12.2513194.Shape and size control of colloidal CdSe nanocrystals in the presence of carboxylate and alkylamine ligands
Lausanne, EPFL, 2019. DOI : 10.5075/epfl-thesis-7298.Material migration and fuel retention studies during the JET carbon divertor campaigns
Fusion Engineering And Design. 2019-01-01. DOI : 10.1016/j.fusengdes.2018.10.002.Full-orbit and drift calculations of fusion product losses due to explosive fishbones on JET
Nuclear Fusion. 2019-01-01. DOI : 10.1088/1741-4326/aaea1e.Measuring fast ions in fusion plasmas with neutron diagnostics at JET
Plasma Physics And Controlled Fusion. 2019-01-01. DOI : 10.1088/1361-6587/aad8a6.Microfluidic and micromechanical in vivo studies of Caenorhabditis elegans
Lausanne, EPFL, 2019. DOI : 10.5075/epfl-thesis-7237.Dimensional tailoring of hydrothermally grown zinc oxide nanostructures in a continuous flow micro reactor
Chemical Communications. 2018-12-04. DOI : 10.1039/c8cc05384g.Tritium retention characteristics in dust particles in JET with ITER-like wall
Nuclear Materials And Energy. 2018-12-01. DOI : 10.1016/j.nme.2018.11.001.Thermal desorption spectrometry of beryllium plasma facing tiles exposed in the JET tokamak (vol 133, pg 135, 2018)
Fusion Engineering And Design. 2018-12-01. DOI : 10.1016/j.fusengdes.2018.08.007.Propagating transport-code input parameter uncertainties with deterministic sampling
Plasma Physics And Controlled Fusion. 2018-12-01. DOI : 10.1088/1361-6587/aae80b.Assessment of the baseline scenario at q(95) similar to 3 for ITER
Nuclear Fusion. 2018-12-01. DOI : 10.1088/1741-4326/aade57.Identification of BeO and BeOxDy in melted zones of the JET Be limiter tiles: Raman study using comparison with laboratory samples
Nuclear Materials And Energy. 2018-12-01. DOI : 10.1016/j.nme.2018.11.008.On the role of finite grid extent in SOLPS-ITER edge plasma simulations for JET H-mode discharges with metallic wall
Nuclear Materials And Energy. 2018-12-01. DOI : 10.1016/j.nme.2018.10.013.Heat flux analysis of Type-I ELM impact on a sloped, protruding surface in the JET bulk tungsten divertor
Nuclear Materials And Energy. 2018-12-01. DOI : 10.1016/j.nme.2018.10.009.3D non-linear MHD simulation of the MHD response and density increase as a result of shattered pellet injection
Nuclear Fusion. 2018-12-01. DOI : 10.1088/1741-4326/aae614.Plasma-wall interaction on the divertor tiles of JET ITER-like wall from the viewpoint of micro/nanoscopic observations
Fusion Engineering And Design. 2018-11-01. DOI : 10.1016/j.fusengdes.2018.01.051.Dust generation in tokamaks: Overview of beryllium and tungsten dust characterisation in JET with the ITER-like wall
Fusion Engineering And Design. 2018-11-01. DOI : 10.1016/j.fusengdes.2018.03.027.Characterisation of neutron generators and monitoring detectors for the in-vessel calibration of JET
Fusion Engineering And Design. 2018-11-01. DOI : 10.1016/j.fusengdes.2018.01.071.Modelling of the neutron production in a mixed beam DT neutron generator
Fusion Engineering And Design. 2018-11-01. DOI : 10.1016/j.fusengdes.2018.04.075.Activation material selection for multiple foil activation detectors in JET TT campaign
Fusion Engineering And Design. 2018-11-01. DOI : 10.1016/j.fusengdes.2018.04.052.Generation of a plasma neutron source for Monte Carlo neutron transport calculations in the tokamak JET
Fusion Engineering And Design. 2018-11-01. DOI : 10.1016/j.fusengdes.2018.04.065.Assessment of the strength of kinetic effects of parallel electron transport in the SOL and divertor of JET high radiative H-mode plasmas using EDGE2D-EIRENE and KIPP codes
Plasma Physics And Controlled Fusion. 2018-11-01. DOI : 10.1088/1361-6587/aae0a0.Preparation for commissioning of materials detritiation facility at Culham Science Centre
Fusion Engineering And Design. 2018-11-01. DOI : 10.1016/j.fusengdes.2018.05.019.Determination of 2D poloidal maps of the intrinsic W density for transport studies in JET-ILW
Review Of Scientific Instruments. 2018-11-01. DOI : 10.1063/1.5046562.Shutdown dose rate measurements after the 2016 Deuterium-Deuterium campaign at JET
Fusion Engineering And Design. 2018-11-01. DOI : 10.1016/j.fusengdes.2018.05.006.Shutdown dose rate neutronics experiment during high performances DD operations at JET
Fusion Engineering And Design. 2018-11-01. DOI : 10.1016/j.fusengdes.2018.05.053.Testing of tritium breeder blanket activation foil spectrometer during JET operations
Fusion Engineering And Design. 2018-11-01. DOI : 10.1016/j.fusengdes.2018.02.005.Microsphere-mediated optical contrast tuning for designing imaging systems with adjustable resolution gain
Scientific Reports. 2018-10-12. DOI : 10.1038/s41598-018-33604-7.Equilibrium reconstruction at JET using Stokes model for polarimetry
Nuclear Fusion. 2018-10-01. DOI : 10.1088/1741-4326/aad751.14 MeV calibration of JET neutron detectors-phase 2: in-vessel calibration
Nuclear Fusion. 2018-10-01. DOI : 10.1088/1741-4326/aad4c1.An improved model for the accurate calculation of parallel heat fluxes at the JET bulk tungsten outer divertor
Nuclear Fusion. 2018-10-01. DOI : 10.1088/1741-4326/aad83e.The upgraded JET gamma-ray cameras based on high resolution/high count rate compact spectrometers
Review Of Scientific Instruments. 2018-10-01. DOI : 10.1063/1.5038839.Development of a new compact gamma-ray spectrometer optimised for runaway electron measurements
Review Of Scientific Instruments. 2018-10-01. DOI : 10.1063/1.5038803.Instrumentation for the upgrade to the JET core charge-exchange spectrometers
Review Of Scientific Instruments. 2018-10-01. DOI : 10.1063/1.5037639.Neutron emission spectroscopy of D plasmas at JET with a compact liquid scintillating neutron spectrometer
Review Of Scientific Instruments. 2018-10-01. DOI : 10.1063/1.5038549.TLD calibration for neutron fluence measurements at JET fusion facility
Nuclear Instruments & Methods In Physics Research Section A-Accelerators Spectrometers Detectors And Associated Equipment. 2018-10-01. DOI : 10.1016/j.nima.2018.07.050.Teaching & PhD
Teaching
Microengineering
PhD Students
Draz Muaz Salama Abdelmonem, Rezaeianaran Farzad,Past EPFL PhD Students
Afshar Ghasemlouy Rana , Atakan Hüseyin Baris , Berdat Daniel , Ciftlik Ata Tuna , Cornaglia Matteo , Dahan Elodie Deborah , Dobrzynska Jagoda Anna , Dong Li , Dupont Emile , Dupouy Diego Gabriel , Huang Xiaopeng , Huszka Gergely , Krenger Roger Philippe , Lehmann Ulrike , Letizia Maria Cristina , Liu Yang , Migliozzi Daniel , Moser Yves , Nguyen Huu Tuan , Orhan Jean-Baptiste Robert , Padovani Rima , Schwander Flurina , Shen Meng , Sivagnanam Venkataragavalu , Tekin Hüseyin Cumhur , Viri Vittorio , Wacker Josias Basil , Yang Hui ,Courses
Microfabrication technologies
The student will learn process techniques and applications of modern micro- and nanofabrication technologies, as practiced in a standard
clean room, with focus on silicon mainstream and microsystems technologies.
Microfabrication practicals
The goal of this course is to introduce students to the practical aspects of some basic micro-fabrication techniques.
Materials and technology of microfabrication
The student will learn procedures and applications of modern microfabrication technologies, as practiced in a clean room environment, in particular modern techniques that go beyond the classical steps of deposition, lithography and etching, with a focus on materials and multidisciplinarity.
MOOC: Micro and Nanofabrication (MEMS)
Micro- and nanofabrication can be taught to students and professionals by textbooks and ex-cathedra lectures, but the real learning comes from seeing the manufacturing steps as they happen. This MOOC will not only explain the basics of microfabrication but also show the practice through videos.
Microstructuring of glass
The course will provide fundamental key aspects governing glass as a material and the microstructuring of glass using a variety of techniques, like dry and wet etching, mechanical and laser machining, as well as sol gel technology. Also concrete application examples will be discussed.
Theoretical Microfluidics
Navier-Stokes equation and basic flow solutions / Hydraulic resistance and compliance
Capillary effects / Diffusion and mixing on the microscale
Electrohydrodynamics and Electroosmosis, Nanofluidics
Dielectrophoresis and Magnetophoresis