EPFL STI IMT LMIS2
BM 3128 (Bâtiment BM)
+41 21 693 67 34
+41 21 693 77 31
Office: BM 3128
EPFL > STI > IEM > LMIS2
Web site: Web site: https://lmis2.epfl.ch/
Fields of expertise
MissionThe Laboratory of Microsystems 2 of Prof. Martin Gijs was established in 1997 and has as mission the development of new microfabrication technologies and to exploit these for applications of industrial interest. We actively participate in national and international research programs. The research of LMIS2 is centered on four themes: - Novel microfabrication technologies - Magnetic applications - Microfluidics - Bio-Micro-Electro-Mechanical Systems (BioMEMS) Novel microfabrication technologies We have established a sol-gel process for the replication of three-dimensional and thin film glass nanostructures. Moreover, we have discovered a new sol-gel process to synthesize borosilicate nanoparticles. Magnetic applications We are working on miniaturised systems for the handling and magnetic transport of magnetic micro- and nanoparticles in microfluidic devices. Microfluidics Chemists and biologists have recognized the utility of microfabricated devices for transporting and manipulating liquids on a sub-?L scale. We are active in the realisation and use of glass and polymer microfluidic chips. BioMEMS We are developing microfluidic channel- and droplet-based microsystems for the handling of magnetic beads for biomedical and mixing applications. We demonstrated a variety of on-chip immuno- and cell-based- assays using magnetic beads in a microfluidic channel as substrate.
BiographyMartin A.M. Gijs received his degree in physics in 1981 from the Katholieke Universiteit Leuven, Belgium and his Ph.D. degree in physics at the same university in 1986. He joined the Philips Research Laboratories in Eindhoven, The Netherlands, in 1987. Subsequently, he has worked there on micro-and nano-fabrication processes of high critical temperature superconducting Josephson and tunnel junctions, the microfabrication of microstructures in magnetic multilayers showing the giant magnetoresistance effect, the design and realisation of miniaturised motors for hard disk applications and the design and realisation of planar transformers for miniaturised power applications. He joined EPFL in 1997. His present interests are in developing technologies for novel magnetic devices, new microfabrication technologies for microsystems fabrication in general and the development and use of microsystems technologies for microfluidic and biomedical applications in particular.
Bubble-enhanced ultrasonic microfluidic chip for rapid DNA fragmentation (vol 22, pg 560, 2022)Lab On A Chip. 2023-03-29. DOI : 10.1039/d3lc90037a.
Efficient AC electrothermal flow (ACET) on-chip for enhanced immunoassaysLab On A Chip. 2023-01-16. DOI : 10.1039/d2lc01147f.
Multi-photon polymerization using upconversion nanoparticles for tunable feature-size printingNanophotonics. 2023-01-10. DOI : 10.1515/nanoph-2022-0598.
Polydimethylsiloxane microstructure-induced acoustic streaming for enhanced ultrasonic DNA fragmentation on a microfluidic chipLab On A Chip. 2022-09-30. DOI : 10.1039/d2lc00366j.
A central arctic extreme aerosol event triggered by a warm air-mass intrusionNature Communications. 2022-09-08. DOI : 10.1038/s41467-022-32872-2.
The enhancement of DNA fragmentation in a bench top ultrasonic water bath with needle-induced air bubbles: Simulation and experimental investigationBiomicrofluidics. 2022-07-01. DOI : 10.1063/5.0101740.
Overview of the MOSAiC expedition: Snow and sea iceElementa-Science Of The Anthropocene. 2022-02-07. DOI : 10.1525/elementa.2021.000046.
Overview of the MOSAiC expedition—AtmosphereElementa: Science of the Anthropocene. 2022-02-07. DOI : 10.1525/elementa.2021.00060.
Selective attention involves a feature-specific sequential release from inhibitory gatingNeuroimage. 2022-02-01. DOI : 10.1016/j.neuroimage.2021.118782.
Source imaging of high-density visual evoked potentials with multi-scale brain parcellations and connectomesScientific Data. 2022-01-19. DOI : 10.1038/s41597-021-01116-1.
Bubble-enhanced ultrasonic microfluidic chip for rapid DNA fragmentationLab On A Chip. 2022-01-06. DOI : 10.1039/d1lc00933h.
Piezoelectric suspended microchannel resonatorsLausanne, EPFL, 2022. DOI : 10.5075/epfl-thesis-9135.
Microfluidic systems for in-flow bioanalytes collectionLausanne, EPFL, 2022. DOI : 10.5075/epfl-thesis-8863.
Ripening of two-dimensional colloidal CdSe nanocrystals into zero-dimensional nanodotsIscience. 2021-12-17. DOI : 10.1016/j.isci.2021.103457.
The connectome spectrum as a canonical basis for a sparse representation of fast brain activityNeuroimage. 2021-12-01. DOI : 10.1016/j.neuroimage.2021.118611.
Effect of inoculum size and antibiotics on bacterial traveling bands in a thin microchannel defined by optical adhesiveMicrosystems & Nanoengineering. 2021-10-22. DOI : 10.1038/s41378-021-00309-3.
Progress on the Upgrade of EDIPO, a 15 T Large Aperture DipoleIeee Transactions On Applied Superconductivity. 2021-08-01. DOI : 10.1109/TASC.2021.3061044.
Antimicrobial susceptibility testing by measuring bacterial oxygen consumption on an integrated platformLab On A Chip. 2021-07-16. DOI : 10.1039/d1lc00296a.
An In Vivo Microfluidic Study of Bacterial Load Dynamics and Absorption in the C. elegans IntestineMicromachines. 2021-07-01. DOI : 10.3390/mi12070832.
Phase calibration of a basic bright-field microscope for 3D metrology of transparent samples at the nanoscale2021-01-01. Conference on Optics and Photonics for Advanced Dimensional Metrology, ELECTR NETWORK, Apr 06-10, 2020. p. 113521N. DOI : 10.1117/12.2559349.
Microfluidic culture platforms for C. elegans bacterial interaction and digestion studies at single-organism resolutionLausanne, EPFL, 2021. DOI : 10.5075/epfl-thesis-8598.
Integration of polymeric membrane/dielectric sphere assemblies in microfluidic chips for enhanced-contrast imaging with low-magnification systemsJournal Of Optical Microsystems. 2021-01-01. DOI : 10.1117/1.JOM.1.1.014001.
Towards an in vitro cardiac model: 3D environment, co-culture, alignment, and mechanical stimulation impact on cell behaviorLausanne, EPFL, 2021. DOI : 10.5075/epfl-thesis-8434.
Microfluidic Platforms for the Study of Bacterial Metabolism and Antimicrobial Susceptibility TestingLausanne, EPFL, 2021. DOI : 10.5075/epfl-thesis-8403.
Insight into the Growth of Anisotropic CdSe Nanocrystals: Attachment of Intrinsically Different Building BlocksJournal Of Physical Chemistry C. 2020-12-17. DOI : 10.1021/acs.jpcc.0c07933.
Nested oscillations and brain connectivity during sequential stages of feature-based attentionNeuroimage. 2020-12-01. DOI : 10.1016/j.neuroimage.2020.117354.
Connectome spectral analysis to track EEG task dynamics on a subsecond scaleNeuroimage. 2020-11-01. DOI : 10.1016/j.neuroimage.2020.117137.
3D nanometrology of transparent objects by phase calibration of a basic bright-field microscope for multiple illumination aperturesOptics Express. 2020-09-14. DOI : 10.1364/OE.404240.
Fast antimicrobial susceptibility testing onEscherichia coliby metabolic heat nanocalorimetryLab On A Chip. 2020-09-07. DOI : 10.1039/d0lc00579g.
Anin vivomicrofluidic study of bacterial transit inC. elegansnematodesLab On A Chip. 2020-08-07. DOI : 10.1039/d0lc00064g.
Magnetic and Mechanical 3-D Modelling of a 15 T Large Aperture Dipole MagnetIeee Transactions On Applied Superconductivity. 2020-06-01. DOI : 10.1109/TASC.2020.2969639.
Force microscopy of the Caenorhabditis elegans embryonic eggshellMicrosystems & Nanoengineering. 2020-05-04. DOI : 10.1038/s41378-020-0137-3.
Automated phenotyping of Caenorhabditis elegans embryos with a high-throughput-screening microfluidic platformMicrosystems & Nanoengineering. 2020-04-06. DOI : 10.1038/s41378-020-0132-8.
PDMS filter structures for size-dependent larval sorting and on-chip egg extraction of C. elegansLab On A Chip. 2020-01-07. DOI : 10.1039/c9lc00949c.
Microfluidic system for Caenorhabditis elegans culture and oxygen consumption rate measurementsLab On A Chip. 2020-01-07. DOI : 10.1039/c9lc00829b.
At the end of scaling: 2D materials for computing and sensing applicationsLausanne, EPFL, 2020. DOI : 10.5075/epfl-thesis-7695.
The Detection of Early Epigenetic Inheritance of Mitochondrial Stress in C. Elegans with a Microfluidic Phenotyping PlatformScientific Reports. 2019-12-17. DOI : 10.1038/s41598-019-55979-x.
A power-balance model of the density limit in fusion plasmas: application to the L-mode tokamakNuclear Fusion. 2019-12-01. DOI : 10.1088/1741-4326/ab3b31.
Rapid high-plex staining and simultaneous imaging for immunophenotyping of tissue sections2019-11-06.
Microfluidics-assisted multiplexed biomarker detection for in situ mapping of immune cells in tumor sectionsMicrosystems & Nanoengineering. 2019-11-06. DOI : 10.1038/s41378-019-0104-z.
Overview of the JET preparation for deuterium-tritium operation with the ITER like-wallNuclear Fusion. 2019-11-01. DOI : 10.1088/1741-4326/ab2276.
Automated Platform for Long-Term Culture and High-Content Phenotyping of Single C. elegans WormsScientific Reports. 2019-10-04. DOI : 10.1038/s41598-019-50920-8.
Microfluidic-based immunohistochemistry for breast cancer diagnosis: a comparative clinical studyVirchows Archiv. 2019-09-01. DOI : 10.1007/s00428-019-02616-7.
CMOS and 3D Printing for NMR Spectroscopy at the Single Embryo ScaleChimia. 2019-08-01. DOI : 10.2533/chimia.2019.635.
The 16 T Dipole Development Program for FCC and HE-LHCIEEE Transactions on Applied Superconductivity. 2019-08-01. DOI : 10.1109/TASC.2019.2900556.
EDGE2D-EIRENE simulations of the influence of isotope effects and anomalous transport coefficients on near scrape-off layer radial electric fieldPlasma Physics And Controlled Fusion. 2019-07-01. DOI : 10.1088/1361-6587/ab1629.
Geodesic acoustic mode evolution in L-mode approaching the L-H transition on JETPlasma Physics And Controlled Fusion. 2019-07-01. DOI : 10.1088/1361-6587/ab1e73.
Spontaneous Formation of CdSe Photoluminescent Nanotubes with Visible-Light Photocatalytic PerformanceAcs Central Science. 2019-06-26. DOI : 10.1021/acscentsci.9b00184.
On a fusion born triton effect in JET deuterium discharges with H-minority ion cyclotron range of frequencies heatingNuclear Fusion. 2019-06-01. DOI : 10.1088/1741-4326/ab19f5.
COREDIV numerical simulation of high neutron rate JET-ILW DD pulses in view of extension to JET-ILW DT experimentsNuclear Fusion. 2019-05-01. DOI : 10.1088/1741-4326/ab0c47.
Comparison of the structure of the plasma-facing surface and tritium accumulation in beryllium tiles from JET ILW campaigns 2011-2012 and 2013-2014Nuclear Materials And Energy. 2019-05-01. DOI : 10.1016/j.nme.2019.02.011.
First mirror test in JET for ITER: Complete overview after three ILW campaignsNuclear Materials And Energy. 2019-05-01. DOI : 10.1016/j.nme.2019.02.009.
Radial variation of heat transport in L-mode JET dischargesNuclear Fusion. 2019-05-01. DOI : 10.1088/1741-4326/ab03e1.
Approximate analytic expressions using Stokes model for tokamak polarimetry and their range of validityPlasma Physics And Controlled Fusion. 2019-05-01. DOI : 10.1088/1361-6587/ab09c2.
Long-lived coupled peeling ballooning modes preceding ELMs on JETNuclear Fusion. 2019-05-01. DOI : 10.1088/1741-4326/ab0031.
High-content, cell-by-cell assessment of HER2 overexpression and amplification: a tool for intratumoral heterogeneity detection in breast cancerLaboratory Investigation. 2019-05-01. DOI : 10.1038/s41374-018-0172-y.
Super-resolution optical imaging: A comparisonMicro And Nano Engineering. 2019-03-01. DOI : 10.1016/j.mne.2018.11.005.
Combining fluorescence-based image segmentation and automated microfluidics for ultrafast cell-by-cell assessment of biomarkers for HER2-type breast carcinomaJournal of Biomedical Optics. 2019-02-01. DOI : 10.1117/1.JBO.24.2.021204.
Multimodal imaging and high-throughput image-processing for drug screening on living organisms on-chipJournal of Biomedical Optics. 2019-02-01. DOI : 10.1117/1.JBO.24.2.021205.
Automated high-content phenotyping from the first larval stage till the onset of adulthood of the nematode Caenorhabditis elegansLab On A Chip. 2019-01-07. DOI : 10.1039/c8lc00863a.
Automated High-Content Phenotyping Of The Nematode C. Elegans At Single Animal Resolution With A Microfluidic Platform2019-01-01. 20th International Conference on Solid-State Sensors, Actuators and Microsystems and Eurosensors XXXIII (TRANSDUCERS and EUROSENSORS), Berlin, GERMANY, Jun 23-27, 2019. p. 2209-2212. DOI : 10.1109/TRANSDUCERS.2019.8808300.
Long-term imaging, automated high-content phenotyping and sorting of C. elegans larvae and embryos using microfluidic platformsLausanne, EPFL, 2019. DOI : 10.5075/epfl-thesis-7509.
An assessment of nitrogen concentrations from spectroscopic measurements in the JET and ASDEX upgrade divertorNuclear Materials And Energy. 2019-01-01. DOI : 10.1016/j.nme.2018.12.012.
Integration of microfluidics and multimodal optics for translational bioanalyticsLausanne, EPFL, 2019. DOI : 10.5075/epfl-thesis-9546.
Studying the roundworm Caenorhabditis elegans using microfluidic chips2019-01-01. Conference on Microfluidics, BioMEMS, and Medical Microsystems XVII, San Francisco, CA, Feb 02-04, 2019. p. 1087518. DOI : 10.1117/12.2513194.
Shape and size control of colloidal CdSe nanocrystals in the presence of carboxylate and alkylamine ligandsLausanne, EPFL, 2019. DOI : 10.5075/epfl-thesis-7298.
Material migration and fuel retention studies during the JET carbon divertor campaignsFusion Engineering And Design. 2019-01-01. DOI : 10.1016/j.fusengdes.2018.10.002.
Full-orbit and drift calculations of fusion product losses due to explosive fishbones on JETNuclear Fusion. 2019-01-01. DOI : 10.1088/1741-4326/aaea1e.
Measuring fast ions in fusion plasmas with neutron diagnostics at JETPlasma Physics And Controlled Fusion. 2019-01-01. DOI : 10.1088/1361-6587/aad8a6.
Microfluidic and micromechanical in vivo studies of Caenorhabditis elegansLausanne, EPFL, 2019. DOI : 10.5075/epfl-thesis-7237.
Dimensional tailoring of hydrothermally grown zinc oxide nanostructures in a continuous flow micro reactorChemical Communications. 2018-12-04. DOI : 10.1039/c8cc05384g.
Tritium retention characteristics in dust particles in JET with ITER-like wallNuclear Materials And Energy. 2018-12-01. DOI : 10.1016/j.nme.2018.11.001.
Thermal desorption spectrometry of beryllium plasma facing tiles exposed in the JET tokamak (vol 133, pg 135, 2018)Fusion Engineering And Design. 2018-12-01. DOI : 10.1016/j.fusengdes.2018.08.007.
Propagating transport-code input parameter uncertainties with deterministic samplingPlasma Physics And Controlled Fusion. 2018-12-01. DOI : 10.1088/1361-6587/aae80b.
Assessment of the baseline scenario at q(95) similar to 3 for ITERNuclear Fusion. 2018-12-01. DOI : 10.1088/1741-4326/aade57.
Identification of BeO and BeOxDy in melted zones of the JET Be limiter tiles: Raman study using comparison with laboratory samplesNuclear Materials And Energy. 2018-12-01. DOI : 10.1016/j.nme.2018.11.008.
On the role of finite grid extent in SOLPS-ITER edge plasma simulations for JET H-mode discharges with metallic wallNuclear Materials And Energy. 2018-12-01. DOI : 10.1016/j.nme.2018.10.013.
Heat flux analysis of Type-I ELM impact on a sloped, protruding surface in the JET bulk tungsten divertorNuclear Materials And Energy. 2018-12-01. DOI : 10.1016/j.nme.2018.10.009.
3D non-linear MHD simulation of the MHD response and density increase as a result of shattered pellet injectionNuclear Fusion. 2018-12-01. DOI : 10.1088/1741-4326/aae614.
Plasma-wall interaction on the divertor tiles of JET ITER-like wall from the viewpoint of micro/nanoscopic observationsFusion Engineering And Design. 2018-11-01. DOI : 10.1016/j.fusengdes.2018.01.051.
Dust generation in tokamaks: Overview of beryllium and tungsten dust characterisation in JET with the ITER-like wallFusion Engineering And Design. 2018-11-01. DOI : 10.1016/j.fusengdes.2018.03.027.
Characterisation of neutron generators and monitoring detectors for the in-vessel calibration of JETFusion Engineering And Design. 2018-11-01. DOI : 10.1016/j.fusengdes.2018.01.071.
Modelling of the neutron production in a mixed beam DT neutron generatorFusion Engineering And Design. 2018-11-01. DOI : 10.1016/j.fusengdes.2018.04.075.
Activation material selection for multiple foil activation detectors in JET TT campaignFusion Engineering And Design. 2018-11-01. DOI : 10.1016/j.fusengdes.2018.04.052.
Generation of a plasma neutron source for Monte Carlo neutron transport calculations in the tokamak JETFusion Engineering And Design. 2018-11-01. DOI : 10.1016/j.fusengdes.2018.04.065.
Assessment of the strength of kinetic effects of parallel electron transport in the SOL and divertor of JET high radiative H-mode plasmas using EDGE2D-EIRENE and KIPP codesPlasma Physics And Controlled Fusion. 2018-11-01. DOI : 10.1088/1361-6587/aae0a0.
Preparation for commissioning of materials detritiation facility at Culham Science CentreFusion Engineering And Design. 2018-11-01. DOI : 10.1016/j.fusengdes.2018.05.019.
Determination of 2D poloidal maps of the intrinsic W density for transport studies in JET-ILWReview Of Scientific Instruments. 2018-11-01. DOI : 10.1063/1.5046562.
Shutdown dose rate measurements after the 2016 Deuterium-Deuterium campaign at JETFusion Engineering And Design. 2018-11-01. DOI : 10.1016/j.fusengdes.2018.05.006.
Shutdown dose rate neutronics experiment during high performances DD operations at JETFusion Engineering And Design. 2018-11-01. DOI : 10.1016/j.fusengdes.2018.05.053.
Testing of tritium breeder blanket activation foil spectrometer during JET operationsFusion Engineering And Design. 2018-11-01. DOI : 10.1016/j.fusengdes.2018.02.005.
Microsphere-mediated optical contrast tuning for designing imaging systems with adjustable resolution gainScientific Reports. 2018-10-12. DOI : 10.1038/s41598-018-33604-7.
Equilibrium reconstruction at JET using Stokes model for polarimetryNuclear Fusion. 2018-10-01. DOI : 10.1088/1741-4326/aad751.
14 MeV calibration of JET neutron detectors-phase 2: in-vessel calibrationNuclear Fusion. 2018-10-01. DOI : 10.1088/1741-4326/aad4c1.
An improved model for the accurate calculation of parallel heat fluxes at the JET bulk tungsten outer divertorNuclear Fusion. 2018-10-01. DOI : 10.1088/1741-4326/aad83e.
The upgraded JET gamma-ray cameras based on high resolution/high count rate compact spectrometersReview Of Scientific Instruments. 2018-10-01. DOI : 10.1063/1.5038839.
Development of a new compact gamma-ray spectrometer optimised for runaway electron measurementsReview Of Scientific Instruments. 2018-10-01. DOI : 10.1063/1.5038803.
Instrumentation for the upgrade to the JET core charge-exchange spectrometersReview Of Scientific Instruments. 2018-10-01. DOI : 10.1063/1.5037639.
Neutron emission spectroscopy of D plasmas at JET with a compact liquid scintillating neutron spectrometerReview Of Scientific Instruments. 2018-10-01. DOI : 10.1063/1.5038549.
TLD calibration for neutron fluence measurements at JET fusion facilityNuclear Instruments & Methods In Physics Research Section A-Accelerators Spectrometers Detectors And Associated Equipment. 2018-10-01. DOI : 10.1016/j.nima.2018.07.050.
Teaching & PhD