Martinus Adela Maria Gijs

Expertise

Microsystems Microfluidics Bio-MEMS Magnetic Applications Microfabrication technologies

Mission

The Laboratory of Microsystems 2 of Prof. Martin Gijs was established in 1997 and has as mission the development of new microfabrication technologies and to exploit these for applications of industrial interest. We actively participate in national and international research programs. The research of LMIS2 is centered on four themes: - Novel microfabrication technologies - Magnetic applications - Microfluidics - Bio-Micro-Electro-Mechanical Systems (BioMEMS) Novel microfabrication technologies We have established a sol-gel process for the replication of three-dimensional and thin film glass nanostructures. Moreover, we have discovered a new sol-gel process to synthesize borosilicate nanoparticles. Magnetic applications We are working on miniaturised systems for the handling and magnetic transport of magnetic micro- and nanoparticles in microfluidic devices. Microfluidics Chemists and biologists have recognized the utility of microfabricated devices for transporting and manipulating liquids on a sub-?L scale. We are active in the realisation and use of glass and polymer microfluidic chips. BioMEMS We are developing microfluidic channel- and droplet-based microsystems for the handling of magnetic beads for biomedical and mixing applications. We demonstrated a variety of on-chip immuno- and cell-based- assays using magnetic beads in a microfluidic channel as substrate.
Martin A.M. Gijs received his degree in physics in 1981 from the Katholieke Universiteit Leuven, Belgium and his Ph.D. degree in physics at the same university in 1986. He joined the Philips Research Laboratories in Eindhoven, The Netherlands, in 1987. Subsequently, he has worked there on micro-and nano-fabrication processes of high critical temperature superconducting Josephson and tunnel junctions, the microfabrication of microstructures in magnetic multilayers showing the giant magnetoresistance effect, the design and realisation of miniaturised motors for hard disk applications and the design and realisation of planar transformers for miniaturised power applications. He joined EPFL in 1997. His present interests are in developing technologies for novel magnetic devices, new microfabrication technologies for microsystems fabrication in general and the development and use of microsystems technologies for microfluidic and biomedical applications in particular.

Selected publications

Droplet-based DNA purification in a magnetic lab-on-a-chip

U. Lehmann, C. Vandevyver, V.K. Parashar, and M.A.M. Gijs
Published in Angewandte Chemie Int. Ed. 45, 3062-3067 (2006); Angewandte Chemie 118, 3132-3137 (2006) in

Will fluidic electronics take off?

M.A.M. Gijs
Published in Nature Nanotechnology 2, 268-270 (2007) in

Borosilicate nanoparticles prepared by exothermic phase separation

Virendra K. Parashar, Jean-Baptiste Orhan, Abdeljalil Sayah, Marco Cantoni, and Martin A.M. Gijs
Published in Nature Nanotechnology 3, 589-594 (2008) in

Full on-chip nanoliter immuno-assay by geometrical magnetic trapping of nanoparticle chains

F. Lacharme, C. Vandevyver, and M.A.M. Gijs
Published in Analytical Chemistry 80, 2905-2910 (2008) in

Label-free detection of DNA with interdigitated micro-electrodes in a fluidic cell

D. Berdat, A.C. Martin Rodriguez, F. Herrera, and M.A.M. Gijs
Published in Lab on a Chip 8, 302-308 (2008) in

Rapid fluidic exchange microsystem for recording of fast ion channel kinetics in Xenopus oocytes

E. Dahan, V. Bize, T. Lehnert, J.-D. Horisberger, and M.A.M. Gijs
Published in Lab on a Chip 8, 1809-1818 (2008) in

On-chip immunoassay using electrostatic assembly of streptavidin-coated bead micropatterns

Venkataragavalu Sivagnanam , Bo Song, Caroline Vandevyver, and Martin A. M. Gijs
Published in Analytical Chemistry 81, 6509-6515 (2009) in

On-chip immuno-agglutination assay with analyte capture by active manipulation of superparamagnetic beads

Y. Moser, T. Lehnert, and M.A.M. Gijs
Published in Lab-on-a-Chip 9, 3261-3267 (2009) in

Monolithic micro-direct methanol fuel cell in PDMS with microfluidic channel-integrated Nafion strip

M. Shen, S. Walter, and M.A.M. Gijs
Published in Journal of Power Sources 193, 761-765 (2009) in

Monolithic CMOS chip for immunofluorescent detection of single magnetic beads

Emile P. Dupont, Estelle Labonne, Caroline Vandevyver, Ulrike Lehmann, Edoardo Charbon and Martin A. M. Gijs
Published in Analytical Chemistry 82, 49-52 (2010) in

Microfluidic protein preconcentrator using microchannel-integrated Nafion strip: experiment and modeling

M. Shen, H. Yang, V. Sivagnanam, and M.A.M. Gijs
Published in Analytical Chemistry 82, 9989-9997 (2010) in

Microfluidic applications of magnetic particles for biological analysis and catalysis

Martin A. M. Gijs, Frédéric Lacharme, and Ulrike Lehmann
Published in Chemical Reviews 110, 1518-1563 (2010) in

M. Gijs