Mykhailo Batiuk

EPFL SV BMI UPGRAEFF
AI 2135 (Bâtiment AI)
Station 19
1015 Lausanne

Expertise

Single cell and spatial genomics (wet/dry lab), glia, psychiatry, neuroscience
I obtained my PhD (2012-2018) in KU Leuven/VIB, Belgium where I investigated astrocyte heterogeneity using single cell transcriptomics. During this period I developed tools to acutely and specifically isolate astrocytes from adult brain and identified five astrocyte subtypes in the cortex and hippocampus of mouse brain expanding previous understanding of astrocyte variability.
Following my PhD, I did my first post-doc in the lab of Konstantin Khodosevich at BRIC, Copenhagen University (2018-2021) where I used single nuclei/spatial transcriptomics and identified neuronal perturbations involved in human schizophrenia. During this period I also managed single cell sequencing core facility and trained researchers to use single cell/spatial genomics tools.
Since mid 2021 I am a post-doctoral researcher in Johannes Gräff lab at EPFL. Here I combine my previous expertise in single cell genomics, psychiatry, and neuron/glia research to decipher epigenetic bases of traumatic memory.

Education

PhD

| PhD, Doctoral School of Biomedical Sciences

2012 – 2018 KU Leuven, Belgium

MSc

| Master's Degree in Biochemistry and Molecular Biology (Cum Laude)

2010 – 2012 Taras Shevchenko National Uniersity of Kyiv

BSc

| Bachelor's Degree in Biology (Cum Laude)

2006 – 2010 Taras Shevchenko National Uniersity of Kyiv

Professionals experiences

Post-doc

Post-doc

PhD Student

Selected publications

Upper cortical layer–driven network impairment in schizophrenia

Mykhailo Y Batiuk, Teadora Tyler, Katarina Dragicevic, Shenglin Mei, Rasmus Rydbirk, Viktor Petukhov, Ruslan Deviatiiarov, Dora Sedmak, Erzsebet Frank, Virginia Feher, Nikola Habek, Qiwen Hu, Anna Igolkina, Lilla Roszik, Ulrich Pfisterer, Diego Garcia-Gonzalez, Zdravko Petanjek, Istvan Adorjan, Peter V Kharchenko, Konstantin Khodosevich
Published in Science Advances, 2022 in

Identification of region-specific astrocyte subtypes at single cell resolution

Mykhailo Y Batiuk, Araks Martirosyan, Jérôme Wahis, Filip de Vin, Catherine Marneffe, Carola Kusserow, Jordan Koeppen, João Filipe Viana, João Filipe Oliveira, Thierry Voet, Chris P Ponting, T Grant Belgard, Matthew G Holt
Published in Nature Communications, 2020 in

An immunoaffinity-based method for isolating ultrapure adult astrocytes based on ATP1B2 targeting by the ACSA-2 antibody

Mykhailo Y Batiuk, Filip de Vin, Sandra I Duqué, Chen Li, Takashi Saito, Takaomi Saido, Mark Fiers, T Grant Belgard, Matthew G Holt
Published in Journal of Biological Chemistry, 2017 in

New Technical Approach for Cross-species Examination of Neuronal Wiring and Adult Neuron-glia Functions

Edwards-Faret G, de Vin F, Slezak M, Gollenbeck L, Karaman R, Shinmyo Y, Batiuk M Y, Pando C M, Urschitz J, Rincon M Y, Moisyadi S, Schnütgen F, Kawasaki H, Schmucker D & Holt M G
Published in Neuroscience, 2022 in

Identification of epilepsy-associated neuronal subtypes and gene expression underlying epileptogenesis

Ulrich Pfisterer, Viktor Petukhov, Samuel Demharter, Johanna Meichsner, Jonatan J Thompson, Mykhailo Y Batiuk, Andrea Asenjo-Martinez, Navneet A Vasistha, Ashish Thakur, Jens Mikkelsen, Istvan Adorjan, Lars H Pinborg, Tune H Pers, Jakob von Engelhardt, Peter V Kharchenko, Konstantin Khodosevich
Published in Nature Communications, 2020 in

Astrocyte layers in the mammalian cerebral cortex revealed by a single-cell in situ transcriptomic map

Omer Ali Bayraktar, Theresa Bartels, Staffan Holmqvist, Vitalii Kleshchevnikov, Araks Martirosyan, Damon Polioudakis, Lucile Ben Haim, Adam M H Young, Mykhailo Y Batiuk, Kirti Prakash, Alexander Brown, Kenny Roberts, Mercedes F Paredes, Riki Kawaguchi, John H Stockley, Khalida Sabeur, Sandra M Chang, Eric Huang, Peter Hutchinson, Erik M Ullian, Martin Hemberg, Giovanni Coppola, Matthew G Holt, Daniel H Geschwind, David H Rowitch
Published in Nature Neuroscience, 2020 in

Compensatory reduction of Cav3.1 expression in thalamocortical neurons of juvenile rats of WAG/Rij model of absence epilepsy

Bizhan R Sharop, Oleksii I Boldyriev, Mykhailo Y Batiuk, Nataliia L Shtefan, Yaroslav M Shuba
Published in Epilepsy Research, 2016 in