Ph.D., Chemical Physics, Research Centre for Technological Lasers of USSR Academy of Science, Moscow, USSR, May 1991.
Diploma in Chemical Physics, Moscow Physical Technical Institute, Moscow, USSR, 1978-1984.
1994-currently Laboratory of Molecular Chemical Physics, Ecole Polytechnique Fédérale de Lausanne, Switzerland. Senior research scientist.
Vibrational/electronic spectroscopy of protonated cold large biological molecules in gas-phase.
Double/triple resonance vibrational overtone spectroscopy of gas phase water up to dissociation threshold.
Double resonance laser isotope separation. Specific properties of IR MPD are employed for highly selective isotope separation on molecules, particular for carbon and silicon isotopes. The US patent # 6,653,587 has been obtained for this technology.
Single/double resonance vibrational overtone spectroscopy of polyatomic molecules cooled in a supersonic jet. Infrared Laser Assisted Photofragment Spectroscopy (IRLAPS) technique, based on infrared multiple photon dissociation (IRMPD) of molecules by CO2 laser, is employed to detect weak overtone transitions.
1992-93 Department of Chemistry, University of Rochester, Rochester, NY, USA. Postdoc. Overtone spectroscopy of polyatomic molecules. IRLAPS detection technique was used for vibrational overtone spectroscopy of jet-cooled molecules.
1986-92 Research Centre for Technological Lasers of USSR Academy of Science, Moscow, Russia. Research engineer to research scientist. Ph.D. research: Infrared absorption spectroscopy of vibrationally excited jet-cooled polyatomic molecules using an original infrared photo-dissociation technique.
1990-91 Asteroid LTD. Head of research division Lasers and applications. The first soviet commercial high rep. rate, high energy excimer laser has been developed, built and sold.
1984 -86 Institute of Chemical Physics of USSR Academy of Science, Moscow. Engineer. Research with Prof. N. N. Semenov. Long-time quenching of chains in reaction F2+H2 inhibited by O2. HF products of the laser induced reaction were detected by MS.
2010- Practical works for 2nd semester students " Chemistry for physicists"
2005-currently: Charge de course at EPFL. Lecturing a Master course for the 4th year students: Lasers and their applications in chemistry (28 hours),
1995- currently: Training and guiding PhD (6) and diploma (2) students,
1995-1998 developing and conducting practical work for the 7th semester students;
PatentT. Rizzo, O. Boiarkine, Laser Separation Method Employing Isotopically Selective Collisional Relaxation, US patent # 6,653,587 B1. Accepted: 2003, priority date 1999.
Old publications1. O.V. Boyarkin, S.I. Ionov, V.N. Bagratashvili, "IR spectroscopy and dynamics of strongly vibrationally excited polyatomic molecules: CF3I." Chem.Phys.Letters 146,106 (1988).
2. O.V. Boyarkin, S.I. Ionov, A.A. Kobakhidze, "IR spectroscopy of polyatomic molecules, vibrationally excited above the dissociation threshold: C2F5I, C3F7I and n-C4F9I.", Spectrochimica Acta 46A, 537 (1990).
3. O.V. Boyarkin, S.I. Ionov, A.A. Stuchebrukhov, M.S. Djidjoev, V.N. Bagratashvili, "IR spectrum of vibrationally excited OsO4 in the region of strong nonlinear interaction of vibrational modes.", J. Phys. Chem. 94, 1294 (1990).
4. O.V. Boyarkin, G.A. Kapralova, A.M. Chaikin, "About length of chain in reaction of fluorine and hydrogen.", Khim. Fizika 9, 1375 (1990) (in Russian).
5. O.V. Boyarkin, S.I. Ionov, A.A. Stuchebrukhov, M.S. Djidjoev, V.N. Bagratashvili, "IR spectroscopy of high-lying states of vibrational quasi-continuum of OsO4 molecule.", Khim. Fiz 10, 1155 (1991) (in Russian).
6. O.V. Boyarkin, "Possibility of isotope selective influence by laser radiation on molecules, excited into vibrational quasicontinuum.", Khim. Fizika 11, 1021 (1992) (in Russian).
7. O.V. Boyarkin, V.N. Bagratashvili, C. Angelie "Photodissociation IR spectroscopy of vibrationally highly excited 13CF3I. Influence of isotopic substitution.", J. Phys. B 25, 4487 (1992).
8. O.V. Boyarkin, V.N. Burimov, V.S. Golybev, A.N. Zherihin, V.L. Popkov "Velocity distribution of Yttrium, occuring under laser ablation of YBa2Cu3O7-x target.", Izvestiya Academii Nayk, ser. Fizicheskaya 57, 90 (1993) (in Russian).
9. A. Kholkin, O. Boiarkine, N. Setter "Transient photocurrents in lead zirconate titanate thin films", Appl. Phys. Lett. 72, 130 (1998).
Revealing Single-Bond Anomeric Selectivity in Carbohydrate-Protein InteractionsJournal Of Physical Chemistry Letters. 2020-05-07. DOI : 10.1021/acs.jpclett.0c00871.
Ultraviolet Photodissociation of Peptides: New Insight on the Mobile Proton ModelJournal Of Experimental And Theoretical Physics. 2020-04-01. DOI : 10.1134/S1063776120030164.
Spectroscopic Evidence for Peptide-Bond-Selective Ultraviolet PhotodissociationThe Journal of Physical Chemistry Letters. 2020. DOI : 10.1021/acs.jpclett.9b03221.
Gas-phase structures reflect the pain-relief potency of enkephalin peptidesPhysical Chemistry Chemical Physics. 2019-09-24. DOI : 10.1039/C9CP04098F.
Interplay of H-Bonds with Aromatics in Isolated Complexes Identifies Isomeric CarbohydratesAngewandte Chemie-International Edition. 2019-05-27. DOI : 10.1002/anie.201902377.
Method for Identification of Threonine Isoforms in Peptides by Ultraviolet Photofragmentation of Cold IonsAnalytical Chemistry. 2019-05-21. DOI : 10.1021/acs.analchem.9b00770.
Cold ion spectroscopy for structural identifications of biomoleculesInternational Reviews in Physical Chemistry. 2018-12-07. DOI : 10.1080/0144235X.2018.1547453.
Intrinsic structure of pentapeptide Leu-enkephalin: geometry optimization and validation by comparison of VSCF-PT2 calculations with cold ion spectroscopyPhys. Chem. Chem. Phys.. 2018-09-07. DOI : 10.1039/C8CP03989E.
Peptide Bond Ultraviolet Absorption Enables Vibrational Cold-Ion Spectroscopy of Nonaromatic PeptidesThe Journal of Physical Chemistry Letters. 2018-08-29. DOI : 10.1021/acs.jpclett.8b02148.
Identification of isoforms of aspartic acid residues in peptides by 2D UV-MS fingerprinting of cold ionsThe Analyst. 2018-07-06. DOI : 10.1039/C7AN02044A.
Initial Steps of Amyloidogenic Peptide Assembly Revealed by Cold-Ion SpectroscopyAngewandte Chemie-International Edition. 2018. DOI : 10.1002/anie.201710188.
High Susceptibility of Histidine to Charge Solvation Revealed by Cold Ion SpectroscopyAngewandte Chemie-International Edition. 2017. DOI : 10.1002/anie.201709437.
A Decapeptide Hydrated by Two Waters: Conformers Determined by Theory and Validated by Cold Ion SpectroscopyJournal Of Physical Chemistry A. 2017. DOI : 10.1021/acs.jpca.7b10357.
Multilaser Conformer-Selective Spectroscopy of Cold Biomolecular Ions in the Gas PhaseLausanne, EPFL, 2017. DOI : 10.5075/epfl-thesis-8012.
Exploring the relevance of gas-phase structures to biology: cold ion spectroscopy of the decapeptide neurokinin APhysical Chemistry Chemical Physics -Cambridge- Royal Society of Chemistry. 2017. DOI : 10.1039/c6cp07953a.
Identification of Isomeric Ephedrines by Cold Ion UV Spectroscopy: Toward Practical ImplementationAnalytical Chemistry. 2017. DOI : 10.1021/acs.analchem.6b04182.
Method and apparatus for the analysis of molecules using mass spectrometry and optical spectroscopyUS2020152435 ; US10546737 ; US2019244798 ; CN107529342 ; US10283336 ; GB2531336 ; JP6445154 ; CN107529342 ; JP2017532563 ; US2017243728 ; EP3207556 ; WO2016059037 ; GB2531336 ; GB201418436 . 2016.
Novel Approaches in Cold Ion Spectroscopy for Structural Characterization of Biomolecules in the Gas PhaseLausanne, EPFL, 2016. DOI : 10.5075/epfl-thesis-7117.
Vibrational Signatures of Conformer-Specific Intramolecular Interactions in Protonated TryptophanJournal of Physical Chemistry A. 2016. DOI : 10.1021/acs.jpca.6b05605.
Nonstatistical UV Fragmentation of Gas-Phase Peptides Reveals Conformers and Their Structural FeaturesJournal of physical chemistry letters. 2016. DOI : 10.1021/acs.jpclett.6b00292.
Resonance Energy Transfer Relates the Gas-Phase Structure and Pharmacological Activity of Opioid PeptidesAngewandte Chemie -International Edition in English-. 2016. DOI : 10.1002/anie.201508915.
Colors for Molecular Masses: Fusion of Spectroscopy and Mass Spectrometry for Identification of BiomoleculesAnalytical Chemistry. 2015. DOI : 10.1021/acs.analchem.5b00822.
Dissociation threshold of H218O: Validating ab initio calculations by state-selective triple-resonance spectroscopyChemical Physics Letters. 2015. DOI : 10.1016/j.cplett.2015.03.036.
Conformational Structures of a Decapeptide Validated by First Principles Calculations and Cold Ion SpectroscopyChemphyschem. 2015. DOI : 10.1002/cphc.201500085.
Cryogenic Methods for the Spectroscopy of Large, Biomolecular IonsGas-phase IR Spectroscopy for the Structural Characterization of Biomolecules; Berlin: Springer, 2015. p. 43-97.
Fragmentation mechanism of UV-excited peptides in the gas phaseJournal of Chemical Physics. 2014. DOI : 10.1063/1.4897158.
Identification of Tyrosine-Phosphorylated Peptides Using Cold Ion SpectroscopyJournal of the American Chemical Society. 2014. DOI : 10.1021/ja5053544.
Cryogenically cooled octupole ion trap for spectroscopy of biomolecular ionsReview of Scientific Instruments. 2014. DOI : 10.1063/1.4868178.
Microhydration Effects on the Encapsulation of Potassium Ion by Dibenzo-18-Crown-6Journal Of The American Chemical Society. 2014. DOI : 10.1021/ja4086066.
Exploring the Mechanism of IR–UV Double-Resonance for Quantitative Spectroscopy of Protonated Polypeptides and ProteinsAngewandte Chemie International Edition. 2013. DOI : 10.1002/anie.201301656.
Accurate bond dissociation energy of water determined by triple-resonance vibrational spectroscopy and ab initio calculationsChemical Physics Letters. 2013. DOI : 10.1016/j.cplett.2013.03.007.
Laser Spectroscopic Study of Cold Host–Guest Complexes of Crown Ethers in the Gas PhaseChemPhysChem. 2013. DOI : 10.1002/cphc.201200746.
Assessing the performance of computational methods for the prediction of the ground state structure of a cyclic decapeptideInternational Journal of Quantum Chemistry. 2013. DOI : 10.1002/qua.24085.
Stark coefficients for highly excited rovibrational states of H2OJournal of Chemical Physics. 2012. DOI : 10.1063/1.4730295.
Global spectroscopy of the water monomerPhilosophical Transactions of the Royal Society of London Series a Mathematical and Physical Sciences. 2012. DOI : 10.1098/rsta.2011.0259.
State-resolved spectroscopy of high vibrational levels of water up to the dissociative continuumPhilosophical Transactions of the Royal Society of London Series A: Mathematical and Physical Sciences. 2012. DOI : 10.1098/rsta.2011.0277.
Interplay of Intra- and Intermolecular H-Bonding in a Progressively Solvated Macrocyclic PeptideScience. 2012. DOI : 10.1126/science.1218709.
Ion Selectivity of Crown Ethers Investigated by UV and IR Spectroscopy in a Cold Ion TrapJournal of Physical Chemistry A. 2012. DOI : 10.1021/jp3011519.
Conformational distribution of bradykinin [bk+2H]2+ revealed by cold ion spectroscopy coupled with FAIMSJournal of the American Society for Mass Spectrometry. 2012. DOI : 10.1007/s13361-012-0384-0.
UV and IR spectroscopy of cold 1,2-dimethoxybenzene complexes with alkali metal ionsPhysical Chemistry Chemical Physics. 2012. DOI : 10.1039/C2CP24018A.
Conformation-Specific Spectroscopy of Peptide Fragment Ions in a low-Temperature Ion TrapJASMS. 2012. DOI : 10.1007/s13361-012-0368-0.
Conformation-specific infrared spectroscopy of gas phase peptides in a cold ion trap2011. 241st National Meeting and Exposition of the American-Chemical-Society (ACS), Anaheim, CA, Mar 27-31, 2011. p. 83-PHYS.
Cold Ion Spectroscopy of Biological Molecules in the Gas PhaseLausanne, EPFL, 2011. DOI : 10.5075/epfl-thesis-5252.
Cold Ion Spectroscopy Reveals the Intrinsic Structure of a DecapeptideAngewandte Chemie, International Edition. 2011. DOI : 10.1002/anie.201100702.
Spectroscopy of mobility-selected biomolecular ionsFaraday Discussions. 2011. DOI : 10.1039/C0FD00004C.
UV Spectroscopic Studies of Cold Alkali Metal Ion–Crown Ether Complexes in the Gas PhaseJournal of the American Chemical Society. 2011. DOI : 10.1021/ja2046205.
Using differential ion mobility as a conformational filter for cold ion spectroscopy2010. p. 311-PHYS.
Fragmentation mechanisms of electronically excited peptides in a cold ion trap2010. p. 176-PHYS.
Communication: Feshbach resonances in the water molecule revealed by state-selective spectroscopy (vol 133, 081103, 2010)Journal Of Chemical Physics. 2010. DOI : 10.1063/1.3504864.
Structure and Bonding of Isoleptic Coinage Metal (Cu, Ag, Au) Dimethylaminonitrenes in the Gas PhaseJournal of the American Chemical Society. 2010. DOI : 10.1021/ja104649k.
Quantitative State-Selective Spectroscopy of Water Below and Above the First Dissociation LimitLausanne, EPFL, 2010. DOI : 10.5075/epfl-thesis-4843.
Feshbach resonances in the water molecule revealed by state-selective spectroscopyJournal of Chemical Physics. 2010. DOI : 10.1063/1.3472312.
A new tandem mass spectrometer for photofragment spectroscopy of cold, gas-phase molecular ionsReview of Scientific Instruments. 2010. DOI : 10.1063/1.3458014.
Highly-resolved Spectra of Gas-phase Gramicidin S: A Benchmark for Peptide Structure CalculationsJournal of the American Chemical Society. 2010. DOI : 10.1021/ja910118j.
State-selective spectroscopy of water up to its first dissociation limitJournal of Chemical Physics. 2009. DOI : 10.1063/1.3273207.
Spectroscopic studies of cold, gas-phase biomolecular ionsInternational Reviews in Physical Chemistry. 2009. DOI : 10.1080/01442350903069931.
Spectroscopy of Protonated Peptides Assisted by Infrared Multiple Photon ExcitationJournal of Physical Chemistry A. 2009. DOI : 10.1021/jp811243w.
Spectroscopy and Conformational Preferences of Gas-Phase HelicesPhysical Chemistry Chemical Physics. 2009. DOI : 10.1039/b814143f.
Spectroscopic probes of cold, gas-phase biomolecular ions: From amino acids to helical peptides2008. 236th National Meeting of the American-Chemical-Society, Philadelphia, PA, Aug 17-21, 2008. p. 12-PHYS.
Collisionally-assisted spectroscopy of water from 27000 to 34000 cm-1Journal of Physical Chemistry A. 2008. DOI : 10.1021/jp805849q.
Effects of N-terminus substitution on the structure and spectroscopy of gas-phase helicesChimia. 2008. DOI : 10.2533/chimia.2008.240.
Multiple-resonance spectroscopy of high vibrational levels in water and methanolLausanne, EPFL, 2008. DOI : 10.5075/epfl-thesis-4067.
Laser isotope separation method employing isotopically selective collisional relaxationEP1742720 ; US6653587 ; JP2003505242 ; WO0108788 ; AU4423800 ; WO0108788 ; EP1072303 . 2007.
Spectroscopic signatures of gas-phase helices: Ac-Phe-(Ala)5-Lys-H+ and Ac-Phe-(Ala)10-Lys-H+Journal of the American Chemical Society. 2007. DOI : 10.1021/ja076507s.
Conformation-specific infrared and ultraviolet spectroscopy of tyrosine-based protonated dipeptidesJournal of Chemical Physics. 2007. DOI : 10.1063/1.2798111.
Conformation-specific spectroscopy and photodissociation of cold, protonated tyrosine and phenylalanineJournal of the American Chemical Society. 2007. DOI : 10.1021/ja0736010.
Approaching the full set of energy levels of waterJournal of Chemical Physics. 2007. DOI : 10.1063/1.2748751.
Isotopically selective collisional vibrational energy transfer in CF3HJournal of Chemical Physics. 2007. DOI : 10.1063/1.2433946.
Conformational dependence of intramolecular vibrational redistribution in methanolJournal of Chemical Physics. 2007. DOI : 10.1063/1.2431367.
Microsolvation effects on the excited state dynamics of protonated tryptophanJournal of the American Chemical Society. 2006. DOI : 10.1021/ja065980n.
A direct measurement of the dissociation energy of waterJournal of Chemical Physics. 2006. DOI : 10.1063/1.2387163.
Efficient, highly selective laser isotope separation of carbon-13Applied Physics B-Lasers and Optics. 2006. DOI : 10.1007/s00340-006-2176-3.
Electronic spectroscopy of cold, protonated tryptophan and tyrosineJournal of the American Chemical Society. 2006. DOI : 10.1021/ja058383u.
Infrared spectroscopy of hydrated amino acids in the gas phase: protonated and lithiated valineJournal of the American Chemical Society. 2006. DOI : 10.1021/ja056079v.
Vibrational overtone spectroscopy of jet-cooled methanol from 5000 to 14000 cm(-1)Journal of Chemical Physics. 2005. DOI : 10.1063/1.1833353.
Collisionally assisted, highly selective laser isotope separation of carbon-13Journal of Chemical Physics. 2004. DOI : 10.1063/1.1822918.
Infrared laser chemistry of trichlorosilane in view of silicon isotope separationJournal of Physical Chemistry A. 2003. DOI : 10.1021/jp0356362.
Collisionally enhanced isotopic selectivity in multiphoton dissociation of vibrationally excited CF3HJournal of Chemical Physics. 2003. DOI : 10.1063/1.1524177.
Nonlinear intensity dependence in the infrared multiphoton excitation and dissociation of methanol pre-excited to different energiesJournal of Chemical Physics. 2002. DOI : 10.1063/1.1501280.
Isotopically selective infrared multiphoton dissociation of vibrationally excited SiH4JOURNAL OF PHYSICAL CHEMISTRY A. 2002. DOI : 10.1021/jp015609g.
Rotational and torsional analysis of the OH-stretch third overtone in (CH3OH)-C-13JOURNAL OF MOLECULAR SPECTROSCOPY. 2002. DOI : 10.1006/jmsp.2001.8506.
Torsion-rotation analysis of OH stretch overtone-torsion combination bands in methanolJournal of Chemical Physics. 2002. DOI : 10.1063/1.1421357.
Collision-free infrared multiphoton dissociation of silaneJOURNAL OF PHYSICAL CHEMISTRY A. 2000. DOI : 10.1021/jp002566f.
Intramolecular energy transfer in highly vibrationally excited methanol. IV. Spectroscopy and dynamics of (CH3OH)-C-13Journal of Chemical Physics. 2000. DOI : 10.1063/1.1323507.
Intramolecular energy transfer in highly vibrationally excited methanol. III. Rotational and torsional analysisJournal of Chemical Physics. 1999. DOI : 10.1063/1.479076.
Intramolecular energy transfer in highly vibrationally excited methanol. II. Multiple time scales of energy redistributionJournal of Chemical Physics. 1999. DOI : 10.1063/1.479075.
Transient photocurrents in lead zirconate titanate thin filmsApplied Physics Letters. 1998. DOI : 10.1063/1.120663.
Highly efficient optically pumped NH3 laser with near diffraction limited outputREVIEW OF SCIENTIFIC INSTRUMENTS. 1998. DOI : 10.1063/1.1149247.
Intramolecular energy transfer in highly vibrationally excited methanol .1. Ultrafast dynamicsJournal of Chemical Physics. 1997. DOI : 10.1063/1.475041.
State-to-state studies of intramolecular dynamics and unimolecular reactionsBERICHTE DER BUNSEN-GESELLSCHAFT. 1997. DOI : 10.1002/bbpc.19971010305.
Secondary time scales of intramolecular vibrational energy redistribution in CF3H studied by vibrational overtone spectroscopyJournal of Chemical Physics. 1996. DOI : 10.1063/1.472482.
ROTATIONAL STATE-SELECTED VIBRATIONAL OVERTONE SPECTROSCOPY OF JET-COOLED MOLECULESJournal of Chemical Physics. 1995. DOI : 10.1063/1.469723.
Vibrational Overtone Spectra of Jet‐Cooled CF3H by Infrared Laser Assisted Photofragment SpectroscopyBerichte der Bunsen-gesellschaft. 1995. DOI : 10.1002/bbpc.19950990340.
Multiple timescales in the intramolecular vibrational energy redistribution of highly excited methanolFaraday Discussions. 1995. DOI : 10.1039/fd9950200167.
Teaching & PhD
Chemistry and Chemical Engineering