The research activity of Paolo De Los Rios focuses on applications of statistical physics to biophysics and to the structure of complex networks. Understanding the physics of proteins is one of the great scientific challenges of the years to come. How do proteins fold to their functional form? How do they work once folded? How do they interact with each other? These and other questions are best approached by the interaction of biology, experimental biophysics and theoretical tools, with particular emphasis on statistical physics since thermal noise plays a determinant role at the scale of proteins. Many systems as different as the Internet and the World Wide Web, social interactions among individuals or market relations between companies, interacting proteins (see above) in the living cell, food web relations in habitats, and many others, find their unifying framework in the theory of complex networks. Although each network is a specific system with its own peculiarities, their large-scale properties can be studied with the tools of statistical physics so to discover that some general principles govern systems that are, at a first examination, very different and unrelated with each other.