Pascal Miéville
Directeur opérationnel
pascal.mieville@epfl.ch +41 21 693 86 25
Nationalité : suisse
Date de naissance : 28.04.1974
+41 21 693 86 25
EPFL > SB > ISIC > LCSA
Web site: Site web: https://lcsa.epfl.ch
Mission
ISIC NMR Core Facility Management
Scientific support to internal and external NMR users
Contact with companies
Scientific support to internal and external NMR users
Contact with companies
Enseignement
- Basic and Advanced NMR I & II, Ecole Doctorale de Chimie (EDCH), EPFL
- Module de RMN intégré aux travaux pratiques de chimie préparative II - SCGC-SB-EPFL
- Module d'introduction à la spectroscopie pour apprentis laborantins - ISIC-SB-EPFL
- Module de RMN intégré aux travaux pratiques de chimie préparative II - SCGC-SB-EPFL
- Module d'introduction à la spectroscopie pour apprentis laborantins - ISIC-SB-EPFL
Commissions et associations professionnelles
Trésorier, membre du comité du Centre de Compétence en Chimie et Toxicologie Analytique (CCCTA).
Publications
Publications Infoscience
Publications Pascal Miéville
[15] Dynamic Nuclear Polarization and Other Magnetic Ideas at EPFL
Chimia. 2012. DOI : 10.2533/chimia.2012.734.[14] Dynamic nuclear polarization of quadrupolar nuclei using cross polarization from protons: surface-enhanced aluminium-27 NMR
Chemical Communications. 2012. DOI : 10.1039/c2cc15905h.[13] Surface Functionalisation of Alumina Ceramic Foams with Organic Ligands
ACS Applied Materials & Interfaces. 2012. DOI : 10.1021/am201638a.[12] Fractional Spin-Labeling of Polymers for Enhancing NMR Sensitivity by Solvent-Free Dynamic Nuclear Polarization
ChemPhysChem. 2011. DOI : 10.1002/cphc.201100630.[11] Synthesis, complexation and NMR relaxation properties of Gd3+ complexes of Mes(DO3A)3
Dalton Transactions. 2011. DOI : 10.1039/c0dt01597k.[10] NMR of Insensitive Nuclei Enhanced by Dynamic Nuclear Polarization
CHIMIA International Journal for Chemistry. 2011. DOI : 10.2533/chimia.2011.260.[9] Extending Timescales and Narrowing Linewidths in NMR
CHIMIA International Journal for Chemistry. 2011. DOI : 10.2533/chimia.2011.652.[8] A spinning thermometer to monitor microwave heating and glass transitions in dynamic nuclear polarization
Magnetic Resonance in Chemistry. 2011. DOI : 10.1002/mrc.2811.[7] Effect of Humic Substance Photoalteration on Lead Bioavailability to Freshwater Microalgae
Environmental Science & Technology. 2011. DOI : 10.1021/es104288y.[6] Fast Characterization of Functionalized Silica Materials by Silicon-29 Surface-Enhanced NMR Spectroscopy Using Dynamic Nuclear Polarization
Journal Of The American Chemical Society. 2011. DOI : 10.1021/ja110791d.[5] Relaxometry of insensitive nuclei: Optimizing dissolution dynamic nuclear polarization
Journal of Magnetic Resonance. 2011. DOI : 10.1016/j.jmr.2011.02.006.[4] Surface Enhanced NMR Spectroscopy by Dynamic Nuclear Polarization
Journal of the American Chemical Society. 2010. DOI : 10.1021/ja104771z.[3] Scavenging Free Radicals To Preserve Enhancement and Extend Relaxation Times in NMR using Dynamic Nuclear Polarization
Angewandte Chemie International Edition. 2010. DOI : 10.1002/anie.201000934.[2] Hyperpolarizing Gases via Dynamic Nuclear Polarization and Sublimation
Physical Review Letters. 2010. DOI : 10.1103/PhysRevLett.105.018104.[1] Kinetics of Yttrium-Ligand Complexation Monitored Using Hyperpolarized 89Y as a Model for Gadolinium in Contrast Agents
Journal of the American Chemical Society. 2010. DOI : 10.1021/ja1013954.Autres publications
Publication Awards
Enantioselective Synthesis of Polycyclic Carbocycles via an AlkynylationAllylationCyclization Strategy Highlight in Synfacts, Thieme Editor February 2015
Livres
coauteur : A. Agoritsas, A. Delay, P. Miéville, Le calcul professionnel au laboratoire de chimie et biologie, 2006, Ed. LEP, Lausanne (CH) http://www.editionslep.ch/detail.php?lep=920157&domaine=Apprendre&theme=2Secondaire%20II coauteur et coordinateur : B.Curchod, J.Gonthier, P.Miéville, J. Risse, Introduction à la chimie, 2012, Ed. LEP, Lausanne (CH) http://www.editionslep.ch/detail.php?lep=912006&domaine=Apprendre&theme=2Secondaire%20II traducteur : J. Keeler (trad P.Miéville), Comprendre la RMN (traduction de Understanding NMR 2nd Ed.), Fev. 2015, Editions PPUR, Lausanne (CH) http://www.ppur.org/en/product/712/9782889150724/Comprendre%20la%20RMN%20
Articles de vulgarisation
IRM et IRMf : Principes, limites et applications, P. Miéville et B. Curchod, Prisme / Revue pédagogique HEPL/N°12/Mai 2010
Brevets
Sami Jannin (Lausanne, CH) Pascal Mieville (Geneve, CH) Geoffrey Bodenhausen (Paris, FR), Method for NMR spectroscopy or MRI measurements using dissolution dynamic nuclear polarization (DNP) with scavenging of free radicals, Bruker BioSpin AG ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL), IPC8 Class: AG01R3348FI , USPC Class: 324309, Publication date: 07/21/2011 , Patent application number: 20110175611
Enseignement & Phd
Other teaching
AUTRES INSTITUTIONS ------------------------ Université de Genève, Ecole de Pharmacie Romande EPGL, Cours d'école doctorale, RMN STAGES -------- Master & Semester Projects 2011 Mylène Maurin (EPFL-ISIC-LSPN), DNP without glass-forming solvents, Master Project 2013 Maude Meystre (EPFL-ISIC-LCIB), DOSY aggregation study of Pyrenbutyric acid, Semester Project Travail de diplôme HES (HES-so Valais Sion) 2015 Gilles Levrand (HES-vs), Développement et implémentation d'un algorithme d'automatisation des acquisitions NMR-DOSY. Travail de fin de BTS (France) 2014 Léonor Bastide (Laraque, Toulouse, France), Effet de la force ionique sur le profil d'excitation d'une impulsion sélective. 2014 Alicia Boz (Laraque, Toulouse, France), Effet de la force ionique sur le profil d'excitation d'une impulsion sculptée.