Pascal Miéville

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pascal.mieville@epfl.ch +41 21 693 86 25

Citizenship: suisse

https://orcid.org/0009-0007-0864-4600

Linkedin ID

EPFL SB ISIC SWISSCAT
CH A2 474 (Bâtiment CH)
Station 6
1015 Lausanne

+41 21 693 86 25
Office: CH A2 474
EPFL > SB > ISIC > SWISSCAT

Web site: Web site: https://swisscatplus.ch/

+41 21 693 86 25
EPFL > SB > SB-SCGC > SCGC-ENS

Web site: Web site: https://www.epfl.ch/schools/sb/scgc/

+41 21 693 86 25
EPFL > SB > ISIC > SCI-SB-SG

Web site: Web site: https://gbf.epfl.ch/

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Administrative data

Fields of expertise

Nuclear Magnetic Resonance
Automation in chemistry
Digital Chemistry

Mission

Leading the conception and development of the Swiss CAT West Hub project. The aim of the Swiss CAT project is to develop a entirely automated and data-driven infrastructure for homogeneous catalysis discovery and optimization. Teaching digital and automation chemistry to Master students

Publications

Selected publications

Samantha L. Anderson, Andrzej Gładysiak, Peter G. Boyd, Christopher P. Ireland, Pascal Miéville, Davide Tiana, Bess Vlaisavljevich, Pascal Schouwink, Wouter van Beek, Kevin J. Gagnon, Berend Smit and Kyriakos C. Stylianou CrystEngComm, 2017, Advance Article DOI: 10.1039/C7CE00589J, Paper	Formation pathways of metal–organic frameworks proceeding through partial dissolution of the metastable phase
Daniele Mammoli, Estel Canet, Roberto Buratto, Pascal Miéville, Lothar Helm, and Geoffrey Bodenhausen Scientific Reports \| 6:38492 \| DOI: 10.1038/srep38492, 23 Dec 2016	Collisional cross-section of water molecules in vapour studied by means of 1H relaxation in NMR
Christine Gonzales; Hikari A.I. Yoshihara; Nahzli Dilek; Julie Leignadier; Melita Irving; Pascal Mieville; Lothar Helm; Olivier Michielin; Juerg Schwitter PLOS ONE \| DOI:10.1371/journal.pone.0164557 October 13, 2016	In-vivo detection and tracking of T cells in various organs in a melanoma tumor model by 19F-fluorine MRS/MRI.
Jan Maciejewski, Adam Sobczuk, Alex Claveau, Adrien G. Nicolai, Riccardo Petraglia, Luca Cervini, Emilie Baudat, Pascal Mieville, Daniele Fazzi, Clemence Corminboeuf, Giuseppe Sforazzini Chem. Sci., 2016, Advance Article DOI: 10.1039/c6sc03196j	Photochromic Torsional Switch (PTS): a Light-Driven Actuator for the Dynamic Tuning of π-Conjugation Extension
Basile Vuichoud, Aurélien Bornet, Florian de Nanteuil, Jonas Milani, Estel Canet, Xiao Ji, Pascal Miéville, Emmanuelle Weber, Dennis Kurzbach, Andrea Flamm, Robert Konrat, Alvar D. Gossert, Sami Jannin, Geoffrey Bodenhausen Chem. Eur. J., 22, 41, 2016 DOI: 10.1002/chem.201602506	Filterable Agents for Hyperpolarization of Water, Metabolites, and Proteins
Elizabeth Allen, Pascal Mieville, Carmen M. Warren, Sadegh Saghafinia, Leanne Li, Mei-Wen Peng, Douglas Hanahan 2016, Cell Reports 15, 1–17, http://dx.doi.org/10.1016/j.celrep.2016.04.029	Metabolic Symbiosis Enables Adaptive Resistance to Anti-angiogenic Therapy that Is Dependent on mTOR Signaling
Isabelle A.M. Worms, David Addenmatten, Pascal Mieville, Jacqueline Traber, Vera I. Slaveykova online, jan 2015, doi:10.1016/j.chemosphere.2014.10.093	Phototransformation of pedogenic humic acid and consequences for Cd, Cu and Pb speciation and bioavailability to green microalgae
Jonas Milani Basile Vuichoud Aurelien Bornet Pascal Mi�ville Roger Mottier Sami Jannin Geoffrey Bodenhausen Review of Scientific Instruments 85, 103505 (2014)	A Magnetic Path to Shelter Hyperpolarized Fluids
Vita, Maria Victoria; Mi�ville, Pascal; Waser, Jerome Org. Lett. 2014, 16, ASAP. (DOI: 10.1021/ol5028333)	Enantioselective Synthesis of Polycyclic Carbocycles via an Alkynylation-Allylation-Cyclization Strategy
Perez Linde, A. J. Carnevale, D. Sinkiewicz, A. Mi�ville, P. Bodenhausen, G. Magnetic Resonance in Chemistry, 2014 DOI: 10.1002/mrc.4138	Dynamic Nuclear Polarization Enhancement of Protons and Vanadium-51 in the Presence of pH-Dependent Vanadyl Radicals
Hugues Jaccard, Pascal Mi�ville, Caroline Cannizzo, C�dric R. Mayer, Lothar Helm JBIC Journal of Biological Inorganic Chemistry, 2013, 10.1007/s00775-013-1036-y	Dynamic aggregation of the mid-size gadolinium complex {Ph4[Gd(DTTA)(H2O)2]-3}
Aur�lien Bornet, Jonas Milani, Shutao Wang, Daniele Mammoli, Roberto Buratto, Nicola Salvi, Takuya F. Segawa, Veronika Vitzthum, Pascal Mi�ville, Srinivas Chinthalapalli, Angel J. Perez-Linde, Diego Carnevale, Sami Jannin, Marc Caporinia, Simone Ulzegaa, Martial Rey, and Geoffrey Bodenhausen CHIMIA 2012, 66, No. 10, doi:10.2533/chimia.2012.732	Dynamic Nuclear Polarization and Other Magnetic Ideas at EPFL
Horacio Comas, Vincent Laporte, Fran�oise Borcard, Pascal Mi�ville, Franziska Krauss Juillerat, Urs T. Gonzenbach, Lucienne Juillerat-Jeanneret and Sandrine Gerber-Lemaire ACS Appl. Mater. Interfaces, 2012, 4 (2), pp 573�576 DOI: 10.1021/am201638a	Surface Functionalisation of Alumina Ceramic Foams with Organic Ligands
Veronika Vitzthum, Pascal Mi�ville,* Diego Carnevale, Marc A. Caporini, David Gajan, Christophe Cop�ret, Moreno Lelli, Alexandre Zagdoun, Aaron Rossini, Anne Lesage, Lyndon Emsley and Geoffrey Bodenhausen Chem. Commun. 2011, DOI:10.1039/C2CC15905H	Dynamic Nuclear Polarization of Quadrupolar Nuclei Using Cross Polarization from Protons: Surface-Enhanced Aluminum-27 NMR.
T. F. Segawa, A. Bornet, N. Salvi, P. Mi�ville, V. Vitzthum, D. Carnevale, S. Jannin, M. A. Caporini, S. Ulzega, P. R. Vasos, M. Rey, G. Bodenhausen CHIMIA,9, 2011, 65	Extending Timescales and Narrowing Linewidths in NMR
Veronika Vitzthum, Fran�oise Borcard, Sami Jannin, Myl�ne Morin, Pascal Mi�ville, Marc Caporini, Andrzej Sienkiewicz, Sandrine Gerber-Lemaire, and Geoffrey Bodenhausen ChemPhysChem 2011, 12, 2929 � 2932	Fractional spin-labeling of polymers for enhancing NMR sensitivity by dynamic nuclear polarization without glass-forming solvents.
*Pascal Mi�ville, Veronika Vitzthum , Marc A. Caporini, Sami Jannin, Sandrine Gerber-Lemaire, Geoffrey Bodenhausen** Magn. Reson. Chem. 2011, 49, 689�692	A spinning thermometer to monitor microwave heating and glass transitions in dynamic nuclear polarization
M. Lelli, D. Gajan, A. Lesage, M. Caporini, V. Vitzthum, P. Mi�ville, F. Heroguel, F. Rascon, A. Roussey, C. Thieuleux, M. Boualleg, L. Veyre, G. Bodenhausen, C. Coperet, L. Emsley. J. Am. Chem. Soc., 2011, 133 (7), pp 2104�2107 DOI: 10.1021/ja110791d	Fast Characterization of Functionalized Silica Materials by Silicon-29 Surface Enhanced NMR Spectroscopy Using Dynamic Nuclear Polarization
*P. Mi�ville, S. Jannin, L. Helm, G. Bodenhausen,* 2010 fall meeting of the Swiss Chemichal society DSM prize invited article, CHIMIA, accepted 2011	NMR of insensitive nuclei enhanced by Dynamic Nuclear Polarization
J. Spierings, I.A.M. Worms, P. Mi�ville, V. I. Slaveykova, Environ. Sci. Technol., 2011, 45 (8), pp 3452�3458 DOI: 10.1021/es104288y	Effect of humic substance photoalteration on lead bioavailability to freshwater microalgae
P. Mi�ville, H. Jaccard, F. Reviriego, R. Tripier, L.Helm Dalton Trans., 2011, 40, 1�8 \| 1, DOI: 10.1039/c0dt01597k	Synthesis, complexation and NMR relaxation properties of Gd3 complexes of Mes(DO3A)3
*P. Mi�ville, S. Jannin, G. Bodenhausen,** J. Magn. Reson.(2011), doi:10.1016/j.jmr.2011.02.006	Relaxometry of Insensitive Nuclei: Optimizing Dissolution Dynamic Nuclear Polarization,
A. Lesage, M. Lelli, D. B. R. A. Gajan, M. A. Caporini, V. Vitzthum, P. Mi�ville, J. Alauzun, A. Roussey, C. Thieuleux, M. Ahmadi, G. Bodenhausen, C. Cop�ret, and L. Emsley. J.AM.CHEM.SOC., 132:15459-15461, 2010.	Surface Enhanced NMR Spectroscopy by Dynamic Nuclear Polarization.
P. Mi�ville, P. Ahuja, R. Sarkar, S. Jannin, P. R. Vasos, S. Gerber, M. Mishkovsky, A. Comment, R. Gruetter, O. Ouari, P. Tordo, and G. Bodenhausen. Angewandte Chemie International Edition in English, 49:6182-6185, 2010.	Scavenging Free Radicals To Preserve Enhancement and Extend Relaxation Times in NMR using Dynamic Nuclear Polarization
A. Comment, S. Jannin, J.-N. Hyacinthe, P. Mi�ville, R. Sarkar, P. Ahuja, P. R. Vasos, X. Montet, F. Lazeyras, J.-P. Vall�e, P. Hautle, J. A. Konter, B. van den Brandt, J.-P. Ansermet, R. Gruetter, and G. Bodenhausen. Physical Review Letters, 105(1):018104, 2010.	Hyperpolarizing Gases via Dynamic Nuclear Polarization and Sublimation
P. Mi�ville, S. Jannin, L. Helm, and G. Bodenhausen. J.AM.CHEM.SOC., 132(14):5006-5007, 2010.	Kinetics of Yttrium-Ligand Complexation Monitored Using Hyperpolarized 89Y as a Model for Gadolinium in Contrast Agents.

Teaching & PhD

Teaching

Chemistry and Chemical Engineering

PhD Students

Choudhury Leander,

Automated and data-driven laboratory (Master lecture)

Courses

Structural analysis

The aim of this course is to treat three of the major techniques for structural characterization of molecules used in chemistry and chemical engineering: mass spectrometry, NMR, and X-ray techniques.

Automated and data-driven laboratories

In this course, taught by experts from the Swiss CAT West Hub, students will be introduced to key concepts in automation and data-driven chemistry. Using real-world cases, students will learn the theoretical skills and practical tools needed to automate a laboratory.