Philippe André Guy Colin
Nationalité: Française
EPFL SV PTECH PTBTG
B3 5 206.118 (Campus Biotech bâtiment B3)
Ch. des Mines 9
1202 Genève
+41 21 693 95 11
Office: B3 5 206.118
EPFL › SV › PTECH › PTBTG
Expertise
Biologie moléculaire
purification
Mission
- fonctionnement de la plateforme de thérapie
A ce jour Technicien spécialisé en expérimentation animal «in vivo» (rongeurs) à l'EPFL dans le laboratoire d
Publications représentatives
). Direct intracerebral gene transfer of an adenoviral vector expressing tyrosine hydroxylase in a rat model of Parkinson's disease.
1. Horellou, P., Vigne, E., Castel, M. N., Barneoud, P., Colin, P., Perricaudet, M., Delaere, P., and Mallet, J.
Published in . Neuroreport, 6, 49-53.(1994). in
Cell-type-specific expression and regulation of a c-fos-NGF fusion gene in neurons and astrocytes of transgenic mice.
2. Onteniente, B., Horellou, P., Neveu, I., Makeh, I., Suzuki, F., Bourdet, C., Grimber, G., Colin, P., Brachet, P., Mallet, J., Brachet,P., Mallet,J. and Peschanski M.
Published in (1994). Mol Brain Res, 21, 225-234. in
Transplantation to the rat brain of human neural progenitors that were genetically modified using adenoviruses.
Sabate, O., Horellou, P., Vigne, E., Colin, P., Perricaudet, M., Buc-Caron, M. H., and Mallet, J.
Published in (1995) Nat Genet, 9, 256-260. in
Intracerebral tetracycline-dependent regulation of gene expression in grafts of neural precursors.
Corti, O., Horellou, P., Colin, P., Cattaneo, E., and Mallet, J.
Published in (1996). Neuroreport, 7, 1655-1659. in
Intrastriatal injection of an adenoviral vector expressing glial cell-line derived neurotrophic factor prevents dopaminergic neuron degeneration and behavioral impairment in a rat model of Parkinson disease.
Bilang-Bleuel, A., Revah, F., Colin, P., Locquet, I., Robert, J. J., Mallet, J., and Horellou, P.
Published in Proc Natl Acad Sci U S A, 94, 8818-8823.(1997) in
A single adenovirus vector mediates doxycycline-controlled expression of tyrosine hydroxylase in brain grafts of human neural progenitors.
Corti, O., Sabate, O., Horellou, P., Colin, P., Dumas, S., Buchet, D., Buc-Caron, M. H., and Mallet, J.
Published in (1999). Nat Biotechnol, 17, 349-354. in
Long-term doxycycline-controlled expression of human tyrosine hydroxylase after direct adenovirus-mediated gene transfer to a rat model of Parkinson's disease.
Corti, O., Sanchez-Capelo, A., Colin, P., Hanoun, N., Hamon, M., and Mallet, J.
Published in (1999) Proc Natl Acad Sci U S A, 96, 12120-12125. in
Brain-derived neurotrophic factor (BDNF)-mediated protection of striatal neurons in an excitotoxic rat model of Huntington's disease, as demonstrated by adenoviral gene transfer.
Bemelmans, A., Horellou, P., Pradier, L., Brunet, I., Colin, P., and Mallet, J.
Published in (1999) Hum Gene Ther, 10, 2987-2997. in
The HIV-1 DNA flap stimulates HIV vector-mediated cell transduction in the brain.
Zennou V, Serguera C, Sarkis C, Colin P, Perret E, Mallet J, Charneau P
Published in (2001 May)Nat Biotechnol.;19(5):446-50 in
Primary adult human astrocytes as an ex vivo vehicle for beta-glucuronidase delivery in the brain.
Serguera C, Sarkis C, Ridet JL, Colin P, Moullier P, Mallet J.
Published in (2001 Jun)Mol Ther;3(6):875-81. in
Controlled transgene expression by E1-E4-defective adenovirus vectors harbouring a "tet-on" switch system.
Fender P, Jeanson L, Ivanov MA, Colin P, Mallet J, Dedieu JF, Latta-Mahieu M.
Published in (2002 Nov-Dec)J Gene Med;4(6):668-75. in
Transforming growth factor beta1 overexpression in the nigrostriatal system increases the dopaminergic deficit of MPTP mice.
Sanchez-Capelo A, Colin P, Guibert B, Biguet NF, Mallet J.
Published in (2003 Aug)Mol Cell Neurosci. (4):614-25. in
Targeting conditional gene modification into the serotonin neurons of the dorsal raphe nucleus by viraldelivery of the Cre recombinase.
Thevenot E, Cote F, Colin P, He Y, Leblois H, Perricaudet M, Mallet J, Vodjdani G.
Published in (2003 sep)Mol Cell Neurosci.; 24 :139-47. in