Rolf Gruetter

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rolf.gruetter@epfl.ch +41 21 693 44 67

EPFL SB IPHYS LIFMET
CH F1 562 (Bâtiment CH)
Station 6
CH-1015 Lausanne

+41 21 693 44 67
+41 21 693 79 81
Office: CH F1 562
EPFL > SB > IPHYS > LIFMET

Web site: Web site: https://lifmet.epfl.ch/

EPFL SB IPHYS LIFMET
CH F1 562 (Bâtiment CH)
Station 6
CH-1015 Lausanne

+41 21 693 44 67
EPFL > SB > SB-SPH > SPH-ENS

Web site: Web site: https://sph.epfl.ch/

EPFL SB IPHYS LIFMET
CH F1 562 (Bâtiment CH)
Station 6
CH-1015 Lausanne

+41 21 693 44 67
+41 21 693 79 81
EPFL > VPA > VPA-AVP-PGE > AVP-PGE-EDOC > EDPY-ENS

EPFL P-SG CCE
CH C2 397 (Bâtiment CH)
Station 6
CH-1015 Lausanne

+41 21 693 44 67
EPFL > P > P-SG > CCE

Web site: Web site: https://cce.epfl.ch/

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Administrative data

Fields of expertise

Magnetic resonance spectroscopy Magnetic resonance imaging MR instrumentation Spin physics Mathematical models of metabolism Neuroscience of hypoglycemia Energy metabolism In vivo kinetics

Biography

Awards: 1999 Young Investigator Award Plenary Lectureship, International Society for Neurochemistry 2011 Fellow, ESMRMB 2011 Teaching Award, Section Sciences de la Vie, EPFL

Teaching

Fundamentals of biomedical imaging (Master, SPH, SSV, Mineurs) - spring semester, on moodle & filmed, since Feb. 2006 Physique générale I SV (SSV) - fall semester (moodle), since Sept. 2009 Advanced biomedical imaging methods and instrumentation (EDPY) - Fall semester, since Sept. 2006 Minor contributions to courses: Neuroscience for engineers (SSV)- spring semester (moodle) Molecular pahtology and therapy of neurodegenerative diseass (EDNE)

Editorial Boards

Editorial Board, Journal of Neuroscience Research (2001 present) Editorial Board, Magma (2003 present) Editorial Board, Neurochemical Research (2003 present) Editorial Board, ASN Neuro Associate Editor, Frontiers in Neuroenergetics Past appointments: Deputy Editor, Magnetic Resonance in Medicine (1999-2011) Editorial Board, NMR in Biomedicine (2003 2011) Editorial Board, Magnetic Resonance in Medicine (2001- 2004)

Reviewing activity: Journals

Am. J. Physiol. (Metabolism and Endocrinology) Am. J. Physiol. (Integrative and Comparative) Am. J. Physiol. (Cell Physiology) Anal. Biochem., Brain Res. Bull. Brain Res. Rev. Dev. Neurosci., Eur. J. Pediatrics Eur. J. Neurosci. Glycobiology J. Cereb. Blood Flow Metab. J. Magn. Reson., J. Neurochem., J. Neurosci. J. Neurosci. Res. Magn. Reson. Med., Neurochemisty Int. Neuroreport Neurosci. Lett. NMR Biomed., Proc. Natl. Acad. Sci. USA, Radiology Trends in Neuroscienes

Grant Review Boards

National Institute of Health ad hoc member (ongoing, 2001-present) NINDS, study section NSD-B / NSD-C ad hoc member NIDA ad hoc member, Special Emphasis Panels NIDDK ad hoc member, special emphasis panel National Science bodies Fonds National Suisse Dutch Science Foundation National Science Foundation (US) Deutsche Forschungsgesellschaft Foundations Binational Science Foundation Alzheimer Disease Foundation Diabetes Foundation Netherlands Juvenile Diabetes Research Foundation International

List of publications

Is provided here or search

Impact

Citation rates 2000-2010 Shown is number of citations per published item (articles & reviews, source ISI), amounting to 106 publications over the period 2000-2010. Indicated in parentheses is the next best field (i.e. having a lower average citation rate) and its rank of 21 disciplines (see for comparison here ) 2000: 52.0 (1. Molecular Biology) 2001: 54.7 (1. Molecular Biology) 2002: 34.2 (2. Immunology) 2003: 46.2 (1. Molecular Biology) 2004: 39.5 (1. Molecular Biology) 2005: 14.3 (8. Pharmacology) 2006: 14.9 (4. Biochemistry) 2007: 13.7 (3. Neuroscience) 2008: 6.7 (7. Clinical Medicine) 2009: 5.0 (4. Neuroscience) 2010: 0.4 (10. Physics) Average citations/item covering the period 2000-2010 : 20.2 (3. Neuroscience) QRED analysis : 16 publications in 2009, on average cited 4.9 times in 2010 : Q >>100%

Publications

Infoscience publications

Last 5 years

[139] Deletion of Crtc1 leads to hippocampal neuroenergetic impairments associated with depressive-like behavior

A. Cherix; C. Poitry-Yamate; B. Lanz; O. Zanoletti; J. Grosse et al.

Molecular Psychiatry. 2022-10-12. DOI : 10.1038/s41380-022-01791-5.

[138] Hyperpolarized (1-13C)Alaninamide Is a Multifunctional In Vivo Sensor of Aminopeptidase N Activity, pH, and CO2

A. Radaelli; D. Ortiz; A. Michelotti; M. Roche; R. Hata et al.

Acs Sensors. 2022-10-04. DOI : 10.1021/acssensors.2c01203.

[137] Segmenting electroencephalography wires reduces radiofrequency shielding artifacts in simultaneous electroencephalography and functional magnetic resonance imaging at 7 T

T. P. Lê; R. Gruetter; J. Jorge; Ö. Ipek

Magnetic Resonance in Medicine. 2022-05-16. DOI : 10.1002/mrm.29298.

[136] Central nervous system and systemic oxidative stress interplay with inflammation in a bile duct ligation rat model of type C hepatic encephalopathy (vol 178, pg 295, 2022)

K. Pierzchala; D. Simicic; A. Sienkiewicz; D. Sessa; S. Mitrea et al.

Free Radical Biology And Medicine. 2022-03-01. DOI : 10.1016/j.freeradbiomed.2022.01.016.

[135] [13C]bicarbonate labelled from hyperpolarized [1-13C]pyruvate is an in vivo marker of hepatic gluconeogenesis in fasted state

E. Can; J. A. M. Bastiaansen; D.-L. Couturier; R. Gruetter; H. A. I. Yoshihara et al.

Communications Biology. 2022-01-10. DOI : 10.1038/s42003-021-02978-2.

[134] Central nervous system and systemic oxidative stress interplay with inflammation in a bile duct ligation rat model of type C hepatic encephalopathy

K. Pierzchala; D. Simicic; A. Sienkiewicz; D. Sessa; S. Mitrea et al.

Free Radical Biology And Medicine. 2022-01-01. DOI : 10.1016/j.freeradbiomed.2021.12.011.

[133] Probiotics combined with rifaximin influence the neurometabolic changes in a rat model of type C HE

E. Flatt; V. A. McLin; O. Braissant; K. Pierzchala; P. Mastromarino et al.

Scientific Reports. 2021-09-09. DOI : 10.1038/s41598-021-97018-8.

[132] Evaluation of the whole auditory pathway using high-resolution and functional MRI at 7T parallel-transmit

S. Da Costa; J. Clement; R. Gruetter; O. Ipek

Plos One. 2021-09-07. DOI : 10.1371/journal.pone.0254378.

[131] Radical-free hyperpolarized MRI using endogenously occurring pyruvate analogues and UV-induced nonpersistent radicals

C. C. Zanella; A. Capozzi; H. A. Yoshihara; A. Radaelli; A. L. C. Mackowiak et al.

Nmr In Biomedicine. 2021-07-10. DOI : 10.1002/nbm.4584.

[130] Measuring Glycolytic Activity with Hyperpolarized [2H7, U-13C6] D-Glucose in the Naive Mouse Brain under Different Anesthetic Conditions

E. Flatt; B. Lanz; Y. Pilloud; A. Capozzi; M. H. Lerche et al.

Metabolites. 2021-06-23. DOI : 10.3390/metabo11070413.

[129] Dipole-Fed Rectangular Dielectric Resonator Antennas for Magnetic Resonance Imaging at 7 T: The Impact of Quasi-Transverse Electric Modes on Transmit Field Distribution

D. Wenz; R. Gruetter

Frontiers in Physics. 2021-06-15. DOI : 10.3389/fphy.2021.675509.

[128] PIRACY: An Optimized Pipeline for Functional Connectivity Analysis in the Rat Brain

Y. Diao; T. Yin; R. Gruetter; I. Jelescu

Frontiers In Neuroscience. 2021-03-26. DOI : 10.3389/fnins.2021.602170.

[127] Hyperpolarized C-13-glucose magnetic resonance highlights reduced aerobic glycolysis in vivo in infiltrative glioblastoma

M. Mishkovsky; O. Gusyatiner; B. Lanz; C. Cudalbu; I. Vassallo et al.

Scientific Reports. 2021-03-11. DOI : 10.1038/s41598-021-85339-7.

[126] The relationship between EEG and fMRI connectomes is reproducible across simultaneous EEG-fMRI studies from 1.5T to 7T

J. Wirsich; J. Jorge; G. R. Iannotti; E. A. Shamshiri; F. Grouiller et al.

NeuroImage. 2021. DOI : 10.1016/j.neuroimage.2021.117864.

[125] Late post‐natal neurometabolic development in healthy male rats using 1 H and 31 P Magnetic Resonance Spectroscopy

V. Račkayová; D. Simicic; G. Donati; O. Braissant; R. Gruetter et al.

Journal of Neurochemistry. 2021. DOI : 10.1111/jnc.15294.

[124] Excitatory/inhibitory neuronal metabolic balance in mouse hippocampus upon infusion of [U-C-13(6)]glucose

A. Cherix; G. Donati; B. Lizarbe; B. Lanz; C. Poitry-Yamate et al.

Journal Of Cerebral Blood Flow And Metabolism. 2021. DOI : 10.1177/0271678X20910535.

[123] Brain NAD Is Associated With ATP Energy Production and Membrane Phospholipid Turnover in Humans

B. Cuenoud; O. Ipek; M. Shevlyakova; M. Beaumont; S. C. Cunnane et al.

Frontiers In Aging Neuroscience. 2020-12-16. DOI : 10.3389/fnagi.2020.609517.

[122] Contribution of macromolecules to brain H-1 MR spectra: Experts' consensus recommendations

C. Cudalbu; K. L. Behar; P. K. Bhattacharyya; W. Bogner; T. Borbath et al.

Nmr In Biomedicine. 2020-11-25. DOI : 10.1002/nbm.4393.

[121] Magnetic resonance spectroscopy in the rodent brain: Experts' consensus recommendations

B. Lanz; A. Abaei; O. Braissant; I.-Y. Choi; C. Cudalbu et al.

Nmr In Biomedicine. 2020-08-26. DOI : 10.1002/nbm.4325.

[120] C-13 Dynamic Nuclear Polarization using SA-BDPA at 6.7 T and 1.1 K: Coexistence of Pure Thermal Mixing and Well-Resolved Solid Effect

A. Radaelli; H. A. Yoshihara; H. Nonaka; S. Sando; J. H. Ardenkjaer-Larsen et al.

Journal Of Physical Chemistry Letters. 2020-08-20. DOI : 10.1021/acs.jpclett.0c01473.

[119] B(0)shimming for in vivo magnetic resonance spectroscopy: Experts' consensus recommendations

C. Juchem; C. Cudalbu; R. A. de Graaf; R. Gruetter; A. Henning et al.

Nmr In Biomedicine. 2020-06-28. DOI : 10.1002/nbm.4350.

[118] Combined deletion of Glut1 and Glut3 impairs lung adenocarcinoma growth

C. Contat; P.-B. Ancey; N. Zangger; S. Sabatino; J. Pascual et al.

Elife. 2020-06-23. DOI : 10.7554/eLife.53618.

[117] Metabolic and perfusion responses to acute hypoglycemia in the rat cortex: A non-invasive magnetic resonance approach

H. Lei; R. Gruetter

Journal Of Neurochemistry. 2020-05-05. DOI : 10.1111/jnc.15028.

[116] The Appearance of the Warburg Effect in the Developing Avian Eye Characterized In Ovo: How Neurogenesis Can Remodel Neuroenergetics

A. Cherix; L. Brodier; C. Poitry-Yamate; J.-M. Matter; R. Gruetter

Investigative Ophthalmology & Visual Science. 2020-05-01. DOI : 10.1167/iovs.61.5.3.

[115] In vivo detection of d-amino acid oxidase with hyperpolarized d-[1-C-13]alanine

A. Radaelli; R. Gruetter; H. A. I. Yoshihara

Nmr In Biomedicine. 2020-04-23. DOI : 10.1002/nbm.4303.

[114] Impact of aerobic exercise type on blood flow, muscle energy metabolism, and mitochondrial biogenesis in experimental lower extremity artery disease

M. Pellegrin; K. Bouzourène; J.-F. Aubert; C. Bielmann; R. Gruetter et al.

Scientific Reports. 2020. DOI : 10.1038/s41598-020-70961-8.

[113] Glutamine-to-glutamate ratio in the nucleus accumbens predicts effort-based motivated performance in humans

A. V. I. Strasser; G. Luksys; L. Xin; M. Pessiglione; R. Gruetter et al.

Neuropsychopharmacology. 2020. DOI : 10.1038/s41386-020-0760-6.

[112] Metabolic signature in nucleus accumbens for anti-depressant-like effects of acetyl-L-carnitine

A. Cherix; T. Larrieu; J. Grosse; J. Rodrigues; B. McEwen et al.

eLife. 2020. DOI : 10.7554/eLife.50631.

[111] Glucose transporter 2 mediates the hypoglycemia-induced increase in cerebral blood flow

H. Lei; F. Preitner; G. Labouebe; R. Gruetter; B. Thorens

Journal Of Cerebral Blood Flow And Metabolism. 2019-09-01. DOI : 10.1177/0271678X18766743.

[110] N-Acetyl-Cysteine Supplementation Improves Functional Connectivity Within the Cingulate Cortex in Early Psychosis: A Pilot Study

E. Mullier; T. Roine; A. Griffa; L. Xin; P. S. Baumann et al.

International Journal of Neuropsychopharmacology. 2019-08-01. DOI : 10.1093/ijnp/pyz022.

[109] Evolution of the neurochemical profiles in the G93A-SOD1 mouse model of amyotrophic lateral sclerosis

H. Lei; E. A. Dirren; C. Poitry-Yamate; B. Schneider; R. Gruetter et al.

Journal of Cerebral Blood Flow and Metabolism. 2019-07-01. DOI : 10.1177/0271678X18756499.

[108] Improved off‐resonance phase behavior using a phase‐inverted adiabatic half‐passage pulse for 13 C MRS in humans at 7 T

E. Serés Roig; L. Xin; D. Gallichan; V. Mlynarik; R. Gruetter

NMR in Biomedicine. 2019. DOI : 10.1002/nbm.4171.

[107] Multi-slice passband bSSFP for human and rodent fMRI at ultra-high field

O. Reynaud; A. R. da Silva; R. Gruetter; I. O. Jelescu

Journal of Magnetic Resonance. 2019. DOI : 10.1016/j.jmr.2019.05.010.

[106] A combined 32‐channel receive‐loops/8‐channel transmit‐dipoles coil array for whole‐brain MR imaging at 7T

J. Clément; R. Gruetter; Ö. Ipek

Magnetic Resonance in Medicine. 2019. DOI : 10.1002/mrm.27808.

[105] Methodological consensus on clinical proton MRS of the brain: Review and recommendations

M. Wilson; O. Andronesi; P. B. Barker; R. Bartha; A. Bizzi et al.

Magnetic Resonance in Medicine. 2019. DOI : 10.1002/mrm.27742.

[104] Capturing the spatiotemporal dynamics of self-generated, task-initiated thoughts with EEG and fMRI

L. Bréchet; D. Brunet; G. Birot; R. Gruetter; C. M. Michel et al.

NeuroImage. 2019. DOI : 10.1016/j.neuroimage.2019.03.029.

[103] Metabolite concentration changes associated with positive and negative BOLD responses in the human visual cortex: A functional MRS study at 7 Tesla

Y. Boillat; L. Xin; W. van der Zwaag; R. Gruetter

Journal of Cerebral Blood Flow & Metabolism. 2019. DOI : 10.1177/0271678X19831022.

[102] Investigating the variability of cardiac pulse artifacts across heartbeats in simultaneous EEG-fMRI recordings: A 7T study

J. Jorge; C. Bouloc; L. Bréchet; C. M. Michel; R. Gruetter

NeuroImage. 2019. DOI : 10.1016/j.neuroimage.2019.02.021.

[101] Nucleus accumbens neurochemistry in human anxiety: A 7 T 1H-MRS study

A. Strasser; L. Xin; R. Gruetter; C. Sandi

Eur Neuropsychopharmacol. 2019. DOI : 10.1016/j.euroneuro.2018.12.015.

[100] Impact of Caffeine Consumption on Type 2 Diabetes-Induced Spatial Memory Impairment and Neurochemical Alterations in the Hippocampus

J. M. N. Duarte; C. Skoug; H. B. Silva; R. A. Carvalho; R. Gruetter et al.

Frontiers in Neuroscience. 2019. DOI : 10.3389/fnins.2018.01015.

[99] High-fat diet consumption alters energy metabolism in the mouse hypothalamus

B. Lizarbe; A. Cherix; J. M. N. Duarte; J.-R. Cardinaux; R. Gruetter

International Journal of Obesity. 2019. DOI : 10.1038/s41366-018-0224-9.

[98] A human cerebral and cerebellar 8-channel transceive RF dipole coil array at 7T

J. D. Clément; R. Gruetter; Ö. Ipek

Magnetic Resonance in Medicine. 2019. DOI : 10.1002/mrm.27476.

[97] Alterations of Brain Energy Metabolism in Type 2 Diabetic Goto-Kakizaki Rats Measured In Vivo by (13)C Magnetic Resonance Spectroscopy

F.-M. Girault; S. Sonnay; R. Gruetter; J. M. N. Duarte

Neurotoxicity research. 2019. DOI : 10.1007/s12640-017-9821-y.

[96] N-acetylcysteine in a Double-Blind Randomized Placebo-Controlled Trial: Toward Biomarker-Guided Treatment in Early Psychosis

P. Conus; L. Seidman; M. Fournier; L. Xin; M. Cleusix et al.

SCHIZOPHRENIA BULLETIN. 2018. DOI : 10.1093/schbul/sbx093.

[95] N-acetylcysteine add-on treatment leads to an improvement of fornix white matter integrity in early psychosis: a double-blind randomized placebo-controlled trial

P. Klauser; L. Xin; M. Fournier; A. Griffa; M. Cleusix et al.

Translational Psychiatry. 2018. DOI : 10.1038/s41398-018-0266-8.

[94] Nutritional Ketosis Increases NAD+/NADH Ratio in Healthy Human Brain: An in Vivo Study by 31P-MRS

L. Xin; Ö. Ipek; M. Beaumont; M. Shevlyakova; N. Christinat et al.

Frontiers in Nutrition. 2018. DOI : 10.3389/fnut.2018.00062.

[93] In vivo characterization of brain metabolism by 1 H MRS, 13 C MRS and 18 FDG PET reveals significant glucose oxidation of invasively growing glioma cells

M. Lai; I. Vassallo; B. Lanz; C. Poitry-Yamate; M.-F. Hamou et al.

International Journal of Cancer. 2018. DOI : 10.1002/ijc.31299.

[92] Increased hepatic fatty acid polyunsaturation precedes ectopic lipid deposition in the liver in adaptation to high-fat diets in mice

A. F. Soares; J. M. das Neves Duarte; R. Gruetter

Magnetic Resonance Materials in Physics, Biology and Medicine. 2018. DOI : 10.1007/s10334-017-0654-8.

[91] Mapping and characterization of positive and negative BOLD responses to visual stimulation in multiple brain regions at 7T

J. Jorge; p. figueiredo; R. Gruetter; W. Van der Zwaag

Human Brain Mapping. 2018. DOI : 10.1002/hbm.24012.

[90] Feasibility of in vivo measurement of glucose metabolism in the mouse hypothalamus by (1) H-[(13) C] MRS at 14.1T

B. Lizarbe Serra; H. Lei; J. M. das Neves Duarte; B. Lanz; A. Cherix et al.

Magnetic Resonance in Medicine. 2018. DOI : 10.1002/mrm.27129.

[89] Probing cardiac metabolism by hyperpolarized 13C MR using an exclusively endogenous substrate mixture and photo-induced nonpersistent radicals

J. A. M. Bastiaansen; H. A. I. Yoshihara; A. Capozzi; J. Schwitter; R. Gruetter et al.

Magnetic Resonance in Medicine. 2018. DOI : 10.1002/mrm.27122.

[88] Clinical Neuroimaging Using 7 T MRI: Challenges and Prospects

M. I. Vargas; P. Martelli; L. Xin; O. Ipek; F. Grouiller et al.

Journal of neuroimaging : official journal of the American Society of Neuroimaging. 2018. DOI : 10.1111/jon.12481.

[87] Astrocytic and neuronal oxidative metabolism are coupled to the rate of glutamate-glutamine cycle in the tree shrew visual cortex

S. Sonnay; J. Poirot; N. Just; A.-C. Clerc; R. Gruetter et al.

Glia. 2018. DOI : 10.1002/glia.23259.

[86] Cannabis use in early psychosis is associated with reduced glutamate levels in the prefrontal cortex

S. Rigucci; L. Xin; P. Klauser; P. S. Baumann; L. Alameda et al.

Psychopharmacology. 2018. DOI : 10.1007/s00213-017-4745-z.

[85] In vivo (13)C MRS in the mouse brain at 14.1 Tesla and metabolic flux quantification under infusion of [1,6-(13)C2]glucose

M. Lai; B. Lanz; C. Poitry-Yamate; J. F. Romero; C. M. Berset et al.

Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 2018. DOI : 10.1177/0271678X17734101.

[84] Diffusion-weighted MRS of acetate in the rat brain

M. Dehghani; N. Kunz; B. Lanz; H. A. I. Yoshihara; R. Gruetter

NMR in biomedicine. 2017. DOI : 10.1002/nbm.3768.

[83] Influence of physiological noise on accelerated 2D and 3D resting state functional MRI data at 7 T

O. Reynaud; J. Jorge; R. Gruetter; J. P. Marques; W. van der Zwaag

Magnetic resonance in medicine. 2017. DOI : 10.1002/mrm.26823.

[82] Social isolation stress and chronic glutathione deficiency have a common effect on the glutamine-to-glutamate ratio and myo-inositol concentration in the mouse frontal cortex

A. Corcoba; R. Gruetter; K. Q. Do; J. M. N. Duarte

Journal of neurochemistry. 2017. DOI : 10.1111/jnc.14116.

[81] Sexual dimorphism in hepatic lipids is associated with the evolution of metabolic status in mice

A. F. Soares; J. Paz-Montoya; H. Lei; M. Moniatte; R. Gruetter

NMR in biomedicine. 2017. DOI : 10.1002/nbm.3761.

[80] Hierarchical status predicts behavioral vulnerability and nucleus accumbens metabolic profile following chronic social defeat stress.

T. Larrieu; A. Cherix; A. Duque; J. Rodrigues; H. Lei et al.

Curr Biol. 2017. DOI : 10.1016/j.cub.2017.06.027.

[79] How Energy Metabolism Supports Cerebral Function: Insights from 13C Magnetic Resonance Studies In vivo

S. Sonnay; R. Gruetter; J. M. N. Duarte

Frontiers in Neuroscience. 2017. DOI : 10.3389/fnins.2017.00288.

[78] Energy metabolism in the rat cortex under thiopental anaesthesia measured

S. Sonnay; J. M. N. Duarte; N. Just; R. Gruetter

Journal of Neuroscience Research. 2017. DOI : 10.1002/jnr.24032.

[77] Progress towards in vivo brain (13)C-MRS in mice: Metabolic flux analysis in small tissue volumes

M. Lai; R. Gruetter; B. Lanz

Analytical biochemistry. 2017. DOI : 10.1016/j.ab.2017.01.019.

[76] Glycogen Supercompensation in the Rat Brain After Acute Hypoglycemia is Independent of Glucose Levels During Recovery

J. M. N. Duarte; F. D. Morgenthaler; R. Gruetter

Neurochemical research. 2017. DOI : 10.1007/s11064-017-2178-z.

[75] Technical and experimental features of Magnetic Resonance Spectroscopy of brain glycogen metabolism

A. F. Soares; R. Gruetter; H. Lei

Analytical Biochemistry. 2017. DOI : 10.1016/j.ab.2016.12.023.

[74] Studying cyto and myeloarchitecture of the human cortex at ultra-high field with quantitative imaging: R1, R⁎2 and susceptibility

J. P. Marques; D. Khabipova; R. Gruetter

NeuroImage. 2017. DOI : 10.1016/j.neuroimage.2016.12.009.

[73] Prospective head motion correction using FID-guided on-demand image navigators

M. Waszak; P. Falkovskiy; T. Hilbert; G. Bonnier; B. Maréchal et al.

Magnetic resonance in medicine. 2017. DOI : 10.1002/mrm.26364.

[72] Early detection of human glioma sphere xenografts in mouse brain using diffusion MRI at 14.1 T

P. Porcari; M. E. Hegi; H. Lei; -F. Hamou; I. Vassallo et al.

NMR in Biomedicine. 2016. DOI : 10.1002/nbm.3610.

[71] Refined Analysis of Brain Energy Metabolism Using In Vivo Dynamic Enrichment of 13C Multiplets

M. Dehghani M; B. Lanz; J. M. N. Duarte; N. Kunz; R. Gruetter

ASN neuro. 2016. DOI : 10.1177/1759091416632342.

[70] Genetic Polymorphism Associated Prefrontal Glutathione and Its Coupling With Brain Glutamate and Peripheral Redox Status in Early Psychosis

L. Xin; R. Mekle; M. Fournier; P. S. Baumann; C. Ferrari et al.

Schizophrenia bulletin. 2016. DOI : 10.1093/schbul/sbw038.

[69] 3D T 2-weighted imaging at 7T using dynamic kT-points on single-transmit MRI systems

F. Eggenschwiler; K. R. O'Brien; D. Gallichan; R. Gruetter; J. P. Marques

Magma (New York, N.Y.). 2016. DOI : 10.1007/s10334-016-0545-4.

[68] Compartmentalised energy metabolism supporting glutamatergic neurotransmission in response to increased activity in the rat cerebral cortex: A 13C MRS study in vivo at 14.1 T

S. Sonnay; J. M. Duarte; N. Just; R. Gruetter

Journal of Cerebral Blood Flow & Metabolism. 2016. DOI : 10.1177/0271678X16629482.

[67] Simultaneous and interleaved acquisition of NMR signals from different nuclei with a clinical MRI scanner

M. Meyerspeer; A. W. Magill; A. Kuehne; R. Gruetter; E. Moser et al.

Magnetic resonance in medicine. 2016. DOI : 10.1002/mrm.26056.

[66] Glutathione deficit affects the integrity and function of the fimbria/fornix and anterior commissure in mice: relevance for schizophrenia

A. Corcoba; P. Steullet; J. M. N. Duarte; Y. Van de Looij; A. Monin et al.

The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP). 2016. DOI : 10.1093/ijnp/pyv110.

[65] Hyperpolarized 6Li as a probe for hemoglobin oxygenation level

R. Balzan; M. Mishkovsky; Y. Simonenko; R. B. van Heeswijk; R. Gruetter et al.

Contrast Media and Molecular Imaging. 2016. DOI : 10.1002/cmmi.1656.

[64] Three-dimensional echo planar imaging with controlled aliasing: A sequence for high temporal resolution functional MRI

M. Narsude; D. Gallichan; W. Van Der Zwaag; R. Gruetter; J. P. Marques

Magnetic Resonance in Medicine. 2016. DOI : 10.1002/mrm.25835.

[63] Retrospective correction of involuntary microscopic head movement using highly accelerated fat image navigators (3D FatNavs) at 7T

D. Gallichan; J. P. Marques; R. Gruetter

Magnetic Resonance in Medicine. 2016. DOI : 10.1002/mrm.25670.

[62] Quantitative activity-induced manganese-dependent MRI for characterizing cortical layers in the primary somatosensory cortex of the rat

M. Auffret; I. Samim; M. Lepore; R. Gruetter; N. Just

Brain Structure and Function. 2016. DOI : 10.1007/s00429-014-0933-3.

[61] GDH-Dependent Glutamate Oxidation in the Brain Dictates Peripheral Energy Substrate Distribution

M. Karaca; F. Frigerio; S. Migrenne; J. Martin-Levilain; D. Skytt et al.

Cell Reports. 2015. DOI : 10.1016/j.celrep.2015.09.003.

[60] Correcting surface coil excitation inhomogeneities in single-shot SPEN MRI

R. Schmidt; M. Mishkovsky; J.-N. Hyacinthe; N. Kunz; R. Gruetter et al.

Journal of Magnetic Resonance. 2015. DOI : 10.1016/j.jmr.2015.08.018.

[59] In Vivo Longitudinal (1)H MRS Study of Transgenic Mouse Models of Prion Disease in the Hippocampus and Cerebellum at 14.1 T

C. Cudalbu; M. Craveiro; V. Mlynárik; J. Bremer; A. Aguzzi et al.

Neurochemical research. 2015. DOI : 10.1007/s11064-015-1643-9.

[58] Stroking or Buzzing? A Comparison of Somatosensory Touch Stimuli Using 7 Tesla fMRI

W. van der Zwaag; R. Gruetter; R. Martuzzi

PloS One. 2015. DOI : 10.1371/journal.pone.0134610.

[57] Direct noninvasive estimation of myocardial tricarboxylic acid cycle flux in vivo using hyperpolarized 13C magnetic resonance

J. Bastiaansen; T. Cheng; H. Lei; R. Gruetter; A. Comment

Journal of Molecular and Cellular Cardiology. 2015. DOI : 10.1016/j.yjmcc.2015.08.012.

[56] Towards high-quality simultaneous EEG-fMRI at 7T: Detection and reduction of EEG artifacts due to head motion

J. Jorge; F. Grouiller; R. Gruetter; W. Van Der Zwaag; P. Figueiredo

NeuroImage. 2015. DOI : 10.1016/j.neuroimage.2015.07.020.

[55] Characterization of hepatic fatty acids in mice with reduced liver fat by ultra-short echo time (1) H-MRS at 14.1 T in vivo

A. F. Soares; H. Lei; R. Gruetter

NMR in biomedicine. 2015. DOI : 10.1002/nbm.3345.

[54] Physiological noise in human cerebellar fMRI

W. Van Der Zwaag; J. Jorge; D. Butticaz; R. Gruetter

Magnetic Resonance Materials in Physics, Biology and Medicine. 2015. DOI : 10.1007/s10334-015-0483-6.

[53] Distinct contributions of Brodmann areas 1 and 2 to body ownership

R. Martuzzi; W. Van Der Zwaag; S. Dieguez; A. Serino; R. Gruetter et al.

Social Cognitive and Affective Neuroscience. 2015. DOI : 10.1093/scan/nsv031.

[52] Imaging of prolonged BOLD response in the somatosensory cortex of the rat

S. Sonnay; N. Just; J. M. N. Duarte; R. Gruetter

NMR in biomedicine. 2015. DOI : 10.1002/nbm.3263.

[51] Assessment of metabolic fluxes in the mouse brain in vivo using (1)H-[(13)C] NMR spectroscopy at 14.1 Tesla

L. Xin; B. Lanz; H. Lei; R. Gruetter

Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 2015. DOI : 10.1038/jcbfm.2014.251.

[50] Brain energy metabolism measured by 13C magnetic resonance spectroscopy in vivo upon infusion of [3-13C]lactate

J. M. Duarte; F.-M. Girault; R. Gruetter

Journal of Neuroscience Research. 2015. DOI : 10.1002/jnr.23531.

[49] A Modulated Closed Form solution for Quantitative Susceptibility Mapping - A thorough evaluation and comparison to iterative methods based on edge prior knowledge

D. Khabipova; Y. Wiaux; R. Gruetter; J. P. Marques

NeuroImage. 2015. DOI : 10.1016/j.neuroimage.2014.11.038.

[48] Simultaneous EEG–fMRI at ultra-high field: Artifact prevention and safety assessment

J. Jorge; F. Grouiller; Ö. Ipek; R. Stoermer; C. M. Michel et al.

NeuroImage. 2015. DOI : 10.1016/j.neuroimage.2014.10.055.

[47] Single acquisition electrical property mapping based on relative coil sensitivities: A proof-of-concept demonstration

J. P. Marques; D. K. Sodickson; O. Ipek; C. M. Collins; R. Gruetter

Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. 2015. DOI : 10.1002/mrm.25399.

[46] Glutathione deficit impairs myelin maturation: relevance for white matter integrity in schizophrenia patients

A. Monin; P. Baumann; A. Griffa; L. Xin; R. Mekle et al.

Molecular Psychiatry. 2015. DOI : 10.1038/mp.2014.88.

[45] Parallel imaging with phase scrambling

M. Zaitsev; G. Schultz; J. Hennig; R. Gruetter; D. Gallichan

Magnetic Resonance in Medicine. 2015. DOI : 10.1002/mrm.25252.

[44] Fast low-specific absorption rate B0-mapping along projections at high field using two-dimensional radiofrequency pulses

O. Reynaud; D. Gallichan; B. Schaller; R. Gruetter

Magnetic Resonance in Medicine. 2015. DOI : 10.1002/mrm.25217.

[43] A double-quadrature radiofrequency coil design for proton-decoupled carbon-13 magnetic resonance spectroscopy in humans at 7T

E. Serés Roig; A. W. Magill; G. Donati; M. Meyerspeer; L. Xin et al.

Magnetic Resonance in Medicine. 2015. DOI : 10.1002/mrm.25171.

[42] Non-invasive diagnostic biomarkers for estimating the onset time of permanent cerebral ischemia

C. Berthet; L. Xin; L. Buscemi; C. Benakis; R. Gruetter et al.

Journal of Cerebral Blood Flow & Metabolism. 2014. DOI : 10.1038/jcbfm.2014.155.

[41] Optimized MEGA-SPECIAL for in vivo glutamine detection in the rat brain at 14.1 T

M. Craveiro; C. Cudalbu; V. Mlynárik; R. Gruetter

NMR in Biomedicine. 2014. DOI : 10.1002/nbm.3168.

[40] Longitudinal neurochemical modifications in the aging mouse brain measured in vivo by 1H magnetic resonance spectroscopy

J. M. N. Duarte; K. Q. Do; R. Gruetter

Neurobiology of aging. 2014. DOI : 10.1016/j.neurobiolaging.2014.01.135.

[39] Image-Derived Input Function from the Vena Cava for 18F-FDG PET Studies in Rats and Mice

B. Lanz; C. Poitry-Yamate; R. Gruetter

Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2014. DOI : 10.2967/jnumed.113.127381.

[38] Multi-modal assessment of long-term erythropoietin treatment after neonatal hypoxic-ischemic injury in rat brain

Y. van de Looij; A. Chatagner; C. Quairiaux; R. Gruetter; P. S. Hüppi et al.

PloS One. 2014. DOI : 10.1371/journal.pone.0095643.

[37] Experimental peripheral arterial disease: new insights into muscle glucose uptake, macrophage, and T-cell polarization during early and late stages

M. Pellegrin; K. Bouzourène; C. Poitry-Yamate; V. Mlynarik; F. Feihl et al.

Physiological Reports. 2014. DOI : 10.1002/phy2.234.

[36] Clinical Proton MR Spectroscopy in Central Nervous System Disorders

G. Öz; J. R. Alger; P. B. Barker; R. Bartha; A. Bizzi et al.

Radiology. 2014. DOI : 10.1148/radiol.13130531.

[35] Are glutamate and lactate increases ubiquitous to physiological activation? A 1H functional MR spectroscopy study during motor activation in human brain at 7Tesla

B. Schaller; L. Xin; K. O‘Brien; A. Magill; R. Gruetter

NeuroImage. 2014. DOI : 10.1016/j.neuroimage.2014.02.016.

[34] In vivo brain macromolecule signals in healthy and glioblastoma mouse models: 1H magnetic resonance spectroscopy, post-processing and metabolite quantification at 14.1 T

M. Craveiro; V. Clément-Schatlo; D. Marino; R. Gruetter; C. Cudalbu

Journal of Neurochemistry. 2014. DOI : 10.1111/jnc.12673.

[33] Definition and quantification of acute inflammatory white matter injury in the immature brain by MRI/MRS at high magnetic field

G. A. Lodygensky; N. Kunz; E. Perroud; E. Somm; V. Mlynarik et al.

Pediatric Research. 2014. DOI : 10.1038/pr.2013.242.

[32] Protective effects of maternal nutritional supplementation with lactoferrin on growth and brain metabolism

E. Somm; P. Larvaron; Y. Van De Looij; A. Toulotte; A. Chatagner et al.

Pediatric Research. 2014. DOI : 10.1038/pr.2013.199.

[31] Hyperpolarized 13C lactate as a substrate for in vivo metabolic studies in skeletal muscle

J. A. M. Bastiaansen; H. A. I. Yoshihara; Y. Takado; R. Gruetter; A. Comment

Metabolomics. 2014. DOI : 10.1007/s11306-014-0630-5.

[30] MRS glucose mapping and PET joining forces: Re-evaluation of the lumped constant in the rat brain under isoflurane anaesthesia

M. F. Alf; J. M. N. Duarte; H. Lei; S. D. Krämer; V. Mlynarik et al.

Journal of neurochemistry. 2014. DOI : 10.1111/jnc.12667.

[29] Phase-based manganese enhanced MRI, a new methodology to enhance brain cytoarchitectural contrast and study manganese uptake

R. Maddage; J. P. Marques; R. Gruetter

Magnetic Resonance in Medicine. 2014. DOI : 10.1002/mrm.25037.

[28] Is the macromolecule signal tissue-specific in healthy human brain? A 1H MRS study at 7 tesla in the occipital lobe

B. Schaller; L. Xin; R. Gruetter

Magnetic Resonance in Medicine. 2014. DOI : 10.1002/mrm.24995.

[27] Improved temporal resolution for functional studies with reduced number of segments with three-dimensional echo planar imaging

M. Narsude; W. Van Der Zwaag; T. Kober; R. Gruetter; J. P. Marques

Magnetic Resonance in Medicine. 2014. DOI : 10.1002/mrm.24975.

[26] In vivo quantification of neuro-glial metabolism and glial glutamate concentration using 1H-[13C] MRS at 14.1T

B. Lanz; L. Xin; P. Millet; R. Gruetter

Journal of Neurochemistry. 2014. DOI : 10.1111/jnc.12479.

[25] An improved trap design for decoupling multinuclear RF coils

M. Meyerspeer; E. Serés Roig; R. Gruetter; A. W. Magill

Magnetic Resonance in Medicine. 2014. DOI : 10.1002/mrm.24931.

[24] Improving T2 -weighted imaging at high field through the use of kT -points

F. Eggenschwiler; K. R. O'Brien; R. Gruetter; J. P. Marques

Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. 2014. DOI : 10.1002/mrm.24805.

[23] Human finger somatotopy in areas 3b, 1, and 2: A 7T fMRI study using a natural stimulus

R. Martuzzi; W. van der Zwaag; J. Farthouat; R. Gruetter; O. Blanke

Human brain mapping. 2014. DOI : 10.1002/hbm.22172.

[22] Metabolic Flux and Compartmentation Analysis in the Brain In vivo

B. Lanz; R. Gruetter; J. M. N. Duarte

Frontiers in Endocrinology. 2013. DOI : 10.3389/fendo.2013.00156.

[21] Direct mapping of 19F in 19FDG-6P in brain tissue at subcellular resolution using soft X-ray fluorescence

C. Poitry-Yamate; A. Gianoncelli; G. Kourousias; B. Kaulich; M. Lepore et al.

Journal of Physics: Conference Series. 2013. DOI : 10.1088/1742-6596/463/1/012003.

[20] Brain Glucose Transport and Phosphorylation Under Acute Insulin-Induced Hypoglycemia in Mice: An 18F-FDG PET Study

M. F. Alf; J. M. N. Duarte; R. Schibli; R. Gruetter; S. D. Kramer

Journal of Nuclear Medicine. 2013. DOI : 10.2967/jnumed.113.122812.

[19] The C57BL/6J Mouse Exhibits Sporadic Congenital Portosystemic Shunts

C. Cudalbu; V. A. Mclin; H. Lei; J. M. N. Duarte; A.-L. Rougemont et al.

PLoS ONE. 2013. DOI : 10.1371/journal.pone.0069782.

[18] New Developments and Applications of the MP2RAGE Sequence - Focusing the Contrast and High Spatial Resolution R1 Mapping

J. P. Marques; R. Gruetter

PloS One. 2013. DOI : 10.1371/journal.pone.0069294.

[17] Glutamatergic and GABAergic energy metabolism measured in the rat brain by 13C NMR spectroscopy at 14.1 T

J. M. N. Duarte; R. Gruetter

Journal of Neurochemistry. 2013. DOI : 10.1111/jnc.12333.

[16] Unedited in vivo detection and quantification of gamma-aminobutyric acid in the occipital cortex using short-TE MRS at 3 T

J. Near; J. Andersson; E. Maron; R. Mekle; R. Gruetter et al.

NMR in Biomedicine. 2013. DOI : 10.1002/nbm.2960.

[15] 3D Residual Eddy Current Field Characterisation: applied to Diffusion Weighted Magnetic Resonance Imaging

K. O'Brien; A. Daducci; N. Kickler; F. Lazeyras; R. Gruetter et al.

IEEE Transactions on Medical Imaging. 2013. DOI : 10.1109/TMI.2013.2259249.

[14] Single spin-echo T 2 relaxation times of cerebral metabolites at 14.1 T in the in vivo rat brain

L. Xin; G. Gambarota; C. Cudalbu; V. Mlynárik; R. Gruetter

Magma (New York, N.Y.). 2013. DOI : 10.1007/s10334-013-0378-3.

[13] Hepatic glucose sensing is required to preserve β cell glucose competence

P. Seyer; D. Vallois; C. Poitry-Yamate; F. Schütz; S. Metref et al.

The Journal of clinical investigation. 2013. DOI : 10.1172/JCI65538.

[12] In vivo enzymatic activity of acetylCoA synthetase in skeletal muscle revealed by (13)C turnover from hyperpolarized [1-(13)C]acetate to [1-(13)C]acetylcarnitine

J. Bastiaansen; T. Cheng; M. Mishkovsky; J. M. das Neves Duarte; A. Comment et al.

Biochimica et biophysica acta. 2013. DOI : 10.1016/j.bbagen.2013.03.023.

[11] Investigation of field and diffusion time dependence of the diffusion-weighted signal at ultrahigh magnetic fields

N. Kunz; S. V. Sizonenko; P. S. Hüppi; R. Gruetter; Y. van de Looij

NMR in biomedicine. 2013. DOI : 10.1002/nbm.2945.

[10] 9.4-14.1 T small-animal PET-MR imaging: Feasibility analysis of LYSO APD readout via long signal lines

J. A. Neves; R. Bugalho; R. Gruetter; A. W. Magill; C. Ortigao et al.

Nuclear Instruments & Methods In Physics Research Section A-Accelerators Spectrometers Detectors And Associated Equipment. 2013. DOI : 10.1016/j.nima.2012.08.032.

[9] Feasibility and electromagnetic compatibility study of the ClearPEM front-end electronics for simultaneous PET-MR imaging

D. Neves; J. André; R. Bugalho; R. Gruetter; A. Magill et al.

Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment. 2013. DOI : 10.1016/j.nima.2012.08.033.

[8] Characterization of sustained BOLD activation in the rat barrel cortex and Neurochemical consequences

N. Just; L. Xin; H. Frenkel; R. Gruetter

Neuroimage. 2013. DOI : 10.1016/j.neuroimage.2013.02.042.

[7] Quantification of the neurochemical profile using simulated macromolecule resonances at 3 T

B. Schaller; L. Xin; C. Cudalbu; R. Gruetter

NMR in biomedicine. 2013. DOI : 10.1002/nbm.2896.

[6] Net increase of lactate and glutamate concentration in activated human visual cortex detected with magnetic resonance spectroscopy at 7 tesla

B. Schaller; R. Mekle; L. Xin; N. Kunz; R. Gruetter

Journal of neuroscience research. 2013. DOI : 10.1002/jnr.23194.

[5] Feasibility of direct mapping of cerebral fluorodeoxy-D-glucose metabolism in situ at subcellular resolution using soft X-ray fluorescence

C. Poitry-Yamate; A. Gianoncelli; B. Kaulich; G. Kourousias; A. W. Magill et al.

Journal of neuroscience research. 2013. DOI : 10.1002/jnr.23171.

[4] Digit somatotopy in the human cerebellum: A 7T fMRI study

W. van der Zwaag; R. Kusters; A. Magill; R. Gruetter; R. Martuzzi et al.

NeuroImage. 2013. DOI : 10.1016/j.neuroimage.2012.11.041.

[3] Proton T(1) relaxation times of metabolites in human occipital white and gray matter at 7 T

L. Xin; B. Schaller; V. Mlynarik; H. Lu; R. Gruetter

Magnetic Resonance in Medicine. 2013. DOI : 10.1002/mrm.24352.

[2] An in vivo ultrahigh field 14.1 T (1) H-MRS study on 6-OHDA and α-synuclein-based rat models of Parkinson's disease: GABA as an early disease marker

P. Coune; M. Craveiro; M. Gaugler; V. Mlynárik; B. Schneider et al.

NMR in biomedicine. 2013. DOI : 10.1002/nbm.2817.

[1] Which prior knowledge? Quantification of in vivo brain (13) C MR spectra following (13) C glucose infusion using AMARES

B. Lanz; J. M. N. Duarte; N. Kunz; V. Mlynárik; R. Gruetter et al.

Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. 2013. DOI : 10.1002/mrm.24406.

Selected publications

Rolf Gruetter
can be found on Biography tab or click link (google scholar profile)

all papers published

Teaching & PhD

Teaching

Physics

PhD Students

Liu Xinyu, Lê Thanh Phong Kevin, Mosso Jessie Julie, Widmaier Mark Stephan, Wiström Emma Linnea, Xiao Ying,

Past EPFL PhD Students

Auffret Matthieu Pierre , Balzan Riccardo , Bastiaansen Josefina Adriana Maria , Boillat Yohan , Bréchet Lucie , Can Emine , Cheng Tian , Cherix Antoine Timothée , Clément Jérémie Daniel , Craveiro Mélanie , Dehghani Moghadam Masoumeh , Diao Yujian , Eggenschwiler Florent , Flatt Emmanuelle Ines , Forjaco Jorge João Pedro , Gretsch Frédéric , Khabipova Diana , Kober Tobias , Kunz Nicolas , Lai Marta , Lanz Bernard , Lim Songi , Narsude Mayur , Rackayová Veronika , Radaelli Alice , Schaller Benoît , Serés Roig Eulalia , Simicic Dunja , Sonnay Sarah Catherine , Vinckenbosch Elise Marie Catherine , Waszak Maryna Volodimirivna , Xin Lijing , Zanella Claudia Christina , van Heeswijk Ruud ,

Courses

General physics : electromagnetism

An introduction to fluids mechanics, to electromagnetism, and to wave phenomena

Fundamentals of biomedical imaging

The goal of this course is to illustrate how modern principles of basic science approaches are integrated into the major biomedical imaging modalities of importance to biology and medicine, with an emphasis on those of interest to in vivo.