Ruud Hovius
EPFL SB ISIC LCBM
CH B3 424 (Bâtiment CH)
Station 6
CH-1015 Lausanne
Mission
=> Teaching: Lecture courses, tutorials and practicals in biochemistry, biophysical chemistry of membranes and signalling processes. Participating to the Commission d'Enseignement and Commission de l'Ecole Doctorale of Chemistry and Chemical Engineering.
=> Research interests: Protein function and structure, Membrane protein (especially receptors and channels) expression, structure and function, biomolecular interaction, labeling with biophysical probes, fluorescence imaging and assay and sensor techniques, single molecule techniques.
BSc course EPFL : TP Biochem_Biophys
Practical introducing 6th semester Chemistry Bachelor students in genetic engineering, protein expression and purification, and biochemical and biophysical charaterisation of proteins.
MSc course EPFL : Cellular Signalling
Masters course on advanced concepts of various cellular signalling pathways and their interactions
Graduate course : ESONN - Grenoble
Module "Advanced biophysics for microsystems design" à European School on Nanosciences & Nanotechnologies (ESONN.fr) à Grenoble, organisé par IPNG, UJF, CNRS et CEA.
Compétences
Protein structure, expression & purification
Molecular interaction & receptor activation
Fluorescence imaging & spectroscopy
Signalling & sensing
Publications
Infoscience
Enseignement & Phd
Enseignement
- Chemistry and Chemical Engineering,
Programmes doctoraux
- Doctoral Program in Chemistry and Chemical Engineering
Doctorants
Cours
Cellular signalling
Présentation de chemins de signalisation en soulignant le mécanisme d'actions des molécules impliquées, les intéractions moléculaires et le rôle de leur organisation spatio-temporel dans la cellulle, en considérant les dimensions et lesconditions cellulai...
Chemical biology
Ce cours montrera comment les outils de la chimie peuvent être utilisés pour traiter des problèmes importants de la biologie. Par la discussion d'articles de première importance en chimie biologique, les étudiants seront familiarisés avec la recherche à l...
Experimental biochemistry and biophysics
During a semester long experiment students plan and perform the construction from DNA bricks of a fluorescent sensor
protein that will be expressed and purified for characterization by biochemical and spectroscopic methods. A report in the
style of a scie...
Molecular and cellular biophysics II
Recherche
Current interests
Structure and function of proteinsReal-time monitoring of structural changes in receptor proteins and molecular interactions of signalling cascades and scaffolds
Single molecule techniques