Stéphanie Lacour

Bioelectronics integrates principles of electrical engineering to biology, medicine and ultimately health. My lab challenges and seeks to advance our fundamental concepts in man-made electronic systems applied to biology. Specifically, the focus is on designing  and manufacturing electronic devices with mechanical properties close to those of the host biological tissue so that long-term reliability and minimal perturbation are induced in vivo and/or truly wearable systems become possible.  
We use fabrication methods borrowed from the MEMS and microelectronics industries and adapt them to soft substrates like elastomers. We develop novel characterization tools adapted to mechanically compliant bioelectronic circuits. We evaluate in vitro, in animal models and ultimately on humans our soft bioelectronic interfaces

Biography

Stéphanie P. Lacour holds the Bertarelli Foundation Chair in Neuroprosthetic Technology in the School of Engineering at EPFL and leads the Laboratory for Soft Bioelectronic Interfaces.
She received her PhD in Electrical Engineering from INSA de Lyon, France, and completed postdoctoral research at Princeton University and the University of Cambridge. She is the recipient of the 2006 MIT TR35, a University Research Fellowship of the Royal Society, European Research Council ERC Starting and POC Grants, and a SNSF-ERC Consolidator Grant. She was elected a 2015 Young Global Leader by the World Economic Forum.

Post-docs

Clemetine Boutry
Liz Canovic
Aaron Gerratt
Xiaoyang Kang
Jennifer Macron
Hadrien Michaud
Giuseppe Schiavone

PhD students

Florent-Valery Coen
Laurent Dejace
Florian Fallegger
Sandra Gribi
Arthur Hirsch
Frédéric Michoud
Nicolas Vachicouras
Michael Shur

Education

Ph.D.

INSA, Lyon, France

1998-2001

M.Sc.

Integrated Electronic Devices

INSA, Lyon France

1998

Publications

Infoscience publications

LSBI

Guidelines to Study and Develop Soft Electrode Systems for Neural Stimulation

G. Schiavone; X. Kang; F. Fallegger; J. Gandar; G. Courtine et al.

Neuron. 2020-10-28. DOI : 10.1016/j.neuron.2020.10.010.

Stéphanie Lacour

Full Professor

Mission

Biography

Post-docs

PhD students

Education

Publications

Infoscience publications

LSBI

Guidelines to Study and Develop Soft Electrode Systems for Neural Stimulation

Nanoscale Controlled Oxidation of Liquid Metals for Stretchable Electronics and Photonics

Structured nanoscale metallic glass fibres with extreme aspect ratios

A biomimetic electrical stimulation strategy to induce asynchronous stochastic neural activity

Soft Printable Electrode Coating for Neural Interfaces

Human Cochlear Nucleus on 7 Tesla Diffusion Tensor Imaging: Insights Into Micro-anatomy and Function for Auditory Brainstem Implant Surgery

Conformable Hybrid Systems for Implantable Bioelectronic Interfaces

Integration of hybrid material systems in conformable neural interfaces

Biomedical device comprising a mechanically adaptive member

Soft, Implantable Bioelectronic Interfaces for Translational Research

Gallium-Based Thin Films for Wearable Sensors and Electronic Skins

Microstructured thin-film electrode technology enables proof of concept of scalable, soft auditory brainstem implants

Closed-Loop Haptic Feedback Control Using a Self-Sensing Soft Pneumatic Actuator Skin

Gallium‐Based Thin Films for Wearable Human Motion Sensors

Conformable bioelectronic interfaces: Mapping the road ahead

Thin Hydrogel-Elastomer Multilayer Encapsulation for Soft Electronics

When and why performance goals predict exploitation behaviors: An achievement goal complex analysis of the selection function of assessment

Materials chemistry in flexible electronics

Liquid electromigration in gallium-based biphasic thin films

Harnessing the Rheological Properties of Liquid Metals To Shape Soft Electronic Conductors for Wearable Applications

First Biopotential Recordings from a Liquid Crystal Optrode

Soft And Wearable Transducers: Opportunities And Challenges For Daily Use

Automatic clustering of spinal reflexes evoked by epidural electrical stimulation of the cervical spinal cord in non-human primates

Patterned biphasic electrical conductor and methods for producing thereof

Method for manufacturing hybrid soft-rigid electronic devices

Bi-Modal Control of Vacuum-Powered Soft Pneumatic Actuators with Embedded Liquid Metal-Based Strain Sensitive Skin

Microchannel-based technologies for nerve interfacing

Auditory brainstem stimulation with a conformable microfabricated array elicits responses with tonotopically organized components

Three-Dimensional Surface Reconstruction of the Human Cochlear Nucleus: Implications for Auditory Brain Stem Implant Design

Soft microfabricated neural implants: a path towards translational implementation

Soft multimodal neural interfaces for unravelling sensory neurological circuits

Auditory Brainstem Implants: Recent Progress and Future Perspectives

Long-term functionality of a soft electrode array for epidural spinal cord stimulation in a minipig model

A microfabricated nerve-on-a-chip platform for rapid assessment of neural conduction in explanted peripheral nerve fibers

Equilibrium and Out-of-Equilibrium Adherence of Hydrogels against Polymer Brushes

A Method to Form Smooth Films of Liquid Metal Supported by Elastomeric Substrate

Soft implantable neurotechnology: a translational perspective

Efficient transdifferentiation of human dermal fibroblasts into skeletal muscle

Optical cuff for optogenetic control of the peripheral nervous system

Long-term functionality of a soft electrode array for epidural spinal cord stimulation in a minipig model

Selective Recruitment of Arm Motoneurons in Nonhuman Primates Using Epidural Electrical Stimulation of the Cervical Spinal Cord

Engineering reversible elasticity in ductile or brittle thin films and products resulting from said engineering

Uniaxial strain of cultured mouse and rat cardiomyocyte strands slows conduction more when its axis is parallel to impulse propagation than when it is perpendicular

Electronic dura mater soft, multimodal neural interfaces

Controlled Sub-Micrometer Hierarchical Textures Engineered in Polymeric Fibers and Microchannels via Thermal Drawing

Engineering reversible elasticity in ductile and brittle thin films supported by a plastic foil

Stretchable metallization technologies for skin-like transducers

Uniaxial strain of cardiac tissue parallel to impulse propagation slows conduction more than in the perpendicular direction: untangling the effects of stretch on tissue resistance

Method for manufacturing electrical conductors, and electrical conductors manufactured according to same

Method for the electrical passivation of electrode arrays and/or conductive paths in general, and a method for producing stretchable electrode arrays and/or stretchable conductive paths in general

Electronic Dura Mater Meddling in the Central Nervous System

Selective electrical and optical neuromodulation of the central nervous system with conformable microfabricated implants

A Wireless System with Stimulation and Recording Capabilities for Interfacing Peripheral Nerves in Rodents

Synthetic skin for recording and modulating physiological activities

Design and Functional Evaluation of an Epidermal Strain Sensing System for Hand Tracking

Materials and technologies for soft implantable neuroprostheses

Matrix stiffness modulates formation and activity of neuronal networks of controlled architectures

Performance of Indium Gallium Zinc Oxide Thin-Film Transistors in Saline Solution

A regenerative microchannel device for recording multiple single-unit action potentials in awake, ambulatory animals

Intrinsically Stretchable Biphasic (Solid–Liquid) Thin Metal Films

Spatiotemporal neuromodulation therapies engaging muscle synergies improve motor control after spinal cord injury

Stretchable electronic structures formed of thin films integrated with soft heterogeneous substrate

Dorsal Root Ganglia Neurons and Differentiated Adipose-derived Stem Cells: An In Vitro Co-culture Model to Study Peripheral Nerve Regeneration

Chronic multichannel neural recordings from soft regenerative microchannel electrodes during gait

Fibrin Gels as Degradable Matrices for Adipose Stem Cells Encapsulation in Peripheral Nerve Repair

Engineered substrates with embedded strain relief for stretchable thin-film electronics

Interactions of Peripheral Nerve Cells with Soft Micropillar Interfaces

Skin health monitoring

Vestibular contribution to bodily self-consciousness and multisensory cortical processing

Soft flexion sensors integrating strechable metal conductors on a silicone substrate for smart glove applications