Theo Lasser

Nationalité: CH, D

EPFL STI-DO
BM 5143 (Bâtiment BM)
Station 17
1015 Lausanne

Expertise

Optique biomédicale Microscopie Imagerie Optique

Mission

Our lab investigates new optical methods and techniques focusing on biomedical imaging. Current topics of interest are Optical Coherence Microscopy, single particle spectroscopy, Fluorescence microscopy and super resolution imaging. These research efforts are taking place at two complementary levels: · fundamental research on coherence imaging including new detection modalities as well as image processing in close cooperation within our institute and faculty · application-oriented projects in collaboration with researchers in medicine and life science as well as industrial partners.n Our teaching contributions are lecturing several optics courses from Introduction in Optics to post graduate courses in Applied Optics and Optical System Design.
De nationalité allemande, né en 1952 à Lauchheim (Baden-Württemberg, Allemagne). Après des études de physique à l'Université Fridericiana de Karlsruhe il y obtient son diplôme de physique en 1978. En 1979, il rejoint l'Institut de Recherches franco-allemand à Saint-Louis (France) comme collaborateur scientifique. En 1986, il entre à la division de recherche de Carl Zeiss à Oberkochen (Allemagne) où il développe principalement divers systèmes laser principalement pour des applications médicales. Dès 1990, il dirige le laboratoire laser de la division médicale. En 1993, il prend la direction de l'unité "laser d'ophtalmologie". En 1995, il est chargé de restructurer et regrouper les nombreuses activités d'ophtalmologie chez Carl Zeiss et de son transfert à Jena. Durant cette période, il réalise des nouveaux instruments de réfraction, des biomicroscopes et des caméras rétiniennes. Dès janvier 1998, il dirige la recherche de Carl Zeiss à Jena où il initie de nouveaux projets en microscopie, en métrologie optique, en microtechnique et en recherche médicale. En juillet 1998, il est nommé professeur ordinaire en optique biomédicale à l'Institut d'Optique Appliquée. Au sein du Département de microtechnique, son activité de recherche porte sur la optique biomédicale et en particulier la microscopie. Il participe à l'enseignement de l'optique et de microscopie. Short CV 1972 Physics University of Karlsruhe (Germany) 1979 l'Institut de Recherches franco-allemand à Saint-Louis (France) 1986 central research division Carl Zeiss, Oberkochen (Germany) 1990 Med - Division, ophthalmic lasers 1994 Ophthalmology division, Carl Zeiss Jena 1998 Head of Central research Carl Zeiss Jena 1998 full Professor Ecole Polytechnique Federale Lausanne, Switzerland

Publications représentatives

Optical sectioning in wide-field microscopy obtained by dynamic structured light illumination and detection based on a smart pixel detector array.

Mitic, J., T. Anhut, et al.
Published in Optics Letters 28(9): 698-700., 2003 in

Optical coherence tomography - principles and applications.

Fercher, A. F., W. Drexler, et al.
Published in Reports on Progress in Physics 66(2): 239-303., 2003 in

Local coupling-coefficient characterization in fiber Bragg gratings.

Giaccari, P., H. G. Limberger, et al.
Published in Optics Letters 28(8): 598-600., 2003 in

Journal Articles

2024

Open-source microscope add-on for structured illumination microscopy

M. T. M. HannebelleE. RaethS. M. LeitaoT. LukesJ. Pospisil  et al.

Nature Communications. 2024. DOI : 10.1038/s41467-024-45567-7.

2021

Soliton microcomb based spectral domain optical coherence tomography

P. J. MarchandJ. RiemensbergerJ. C. SkehanJ.-J. HoM. H. P. Pfeiffer  et al.

Nature Communications. 2021. DOI : 10.1038/s41467-020-20404-9.

2019

Supervised learning to quantify amyloidosis in whole brains of an Alzheimer's disease mouse model acquired with optical projection tomography

D. NguyenV. UhlmannA. L. PlanchetteP. J. MarchandD. Van de Ville  et al.

Biomedical Optics Express. 2019. DOI : 10.1364/BOE.10.003041.

High-Contrast Imaging of Nanodiamonds in Cells by Energy Filtered and Correlative Light-Electron Microscopy: Toward a Quantitative Nanoparticle-Cell Analysis

S. HanM. RaabeL. HodgsonJ. MantellP. Verkade  et al.

Nano Letters. 2019. DOI : 10.1021/acs.nanolett.9b00752.

2017

Correcting for photodestruction in super-resolution optical fluctuation imaging

Y. PeetersW. VandenbergS. DuwéA. P. BouwensT. Lukes  et al.

Scientific Reports. 2017. DOI : 10.1038/s41598-017-09666-4.

Reduction of Abeta amyloid pathology in APPPS1 transgenic mice in the absence of gut microbiota

T. HarachN. MarungruangN. DuthilleulV. CheathamK. Mc Coy  et al.

Scientific Reports. 2017. DOI : 10.1038/srep41802.

Label-free three-dimensional imaging of Caenorhabditis elegans with visible optical coherence microscopy

S. CoquozP. J. MarchandA. BouwensL. MouchiroudV. Sorrentino  et al.

Plos One. 2017. DOI : 10.1371/journal.pone.0181676.

3D Time-lapse Imaging and Quantification of Mitochondrial Dynamics

M. SisonS. ChakraborttyJ. ExtermannA. NahasP. J. Marchand  et al.

Scientific Reports. 2017. DOI : 10.1038/srep43275.

Massively parallel data processing for quantitative total flow imaging with optical coherence microscopy and tomography

M. SylwestrzakD. SzlagP. J. MarchandA. S. KumarT. Lasser

Computer Physics Communications. 2017. DOI : 10.1016/j.cpc.2017.03.008.

Visible spectrum extended-focus optical coherence microscopy for label-free sub-cellular tomography

P. J. MarchandA. BouwensD. SzlagD. NguyenA. Descloux  et al.

Biomedical Optics Express. 2017. DOI : 10.1364/BOE.8.003343.

Administrations of human adult ischemia-tolerant mesenchymal stem cells and factors reduce amyloid beta pathology in a mouse model of Alzheimer's disease

T. HarachF. JammesC. MullerN. DuthilleulV. Cheatham  et al.

Neurobiology of Aging. 2017. DOI : 10.1016/j.neurobiolaging.2016.11.009.

Quantifying protein densities on cell membranes using super-resolution optical fluctuation imaging

T. LukesD. GlatzovaZ. KvicalovaF. LevetA. Benda  et al.

Nature Communications. 2017. DOI : 10.1038/s41467-017-01857-x.

Interferometric synthetic aperture microscopy for extended focus optical coherence microscopy

S. CoquozA. BouwensP. J. MarchandJ. ExtermannT. Lasser

Optics Express. 2017. DOI : 10.1364/OE.25.030807.

Statistical parametric mapping of stimuli evoked changes in total blood flow velocity in the mouse cortex obtained with extended-focus optical coherence microscopy

P. J. MarchandA. P. BouwensT. BolmontV. K. ShamaeiD. Nguyen  et al.

Biomedical Optics Express. 2017. DOI : 10.1364/BOE.8.000001.

Optical projection tomography for rapid whole mouse brain imaging

D. NguyenP. J. MarchandA. L. PlanchetteJ. NilssonM. Sison  et al.

Biomedical Optics Express. 2017. DOI : 10.1364/BOE.8.005637.

NIR-emitting and photo-thermal active nanogold as mitochondria-specific probes

S. ChakraborttyM. SisonY. WuA. LadenburgerG. Pramanik  et al.

Biomaterials Science. 2017. DOI : 10.1039/c6bm00951d.

2016

Model-free uncertainty estimation in stochastical optical fluctuation imaging (SOFI) leads to a doubled temporal resolution

V. VandenbergS. DuwéM. LeuteneggerB. MoeyaertB. Krajnik  et al.

Biomedical Optics Express. 2016. DOI : 10.1364/BOE.7.000467.

Complementarity of PALM and SOFI for super-resolution live-cell imaging of focal adhesions

H. DeschoutT. LukesA. SharipovD. SzlagL. Feletti  et al.

Nature Communications. 2016. DOI : 10.1038/ncomms13693.

High-speed phase-shifting common-path quantitative phase imaging with a piezoelectric actuator

S. CoquozA. NahasM. SisonA. LopezT. Lasser

Journal of Biomedical Optics (JBO). 2016. DOI : 10.1117/1.JBO.21.12.126019.

Extended-focus optical coherence microscopy for high-resolution imaging of the murine brain

S. TamborskiH. C. LyuH. DolezyczekM. MalinowskaG. Wilczynski  et al.

Biomedical Optics Express. 2016. DOI : 10.1364/BOE.7.004400.

Label-free fast 3D coherent imaging reveals pancreatic islet micro-vascularization and dynamic blood flow

C. BerclazD. SzlagD. NguyenJ. ExtermannA. Bouwens  et al.

Biomedical Optics Express. 2016. DOI : 10.1364/Boe.7.004569.

Compressed imaging by sparse random convolution

D. MarcosT. LasserA. LopezA. Bourquard

Optics Express. 2016. DOI : 10.1364/OE.24.001269.

Longitudinal three-dimensional visualisation of autoimmune diabetes by functional optical coherence imaging

C. BerclazA. Schmidt-ChristensenD. SzlagJ. ExtermannL. Hansen  et al.

Diabetologia. 2016. DOI : 10.1007/s00125-015-3819-x.

Fluorescent Nanodiamond–Gold Hybrid Particles for Multimodal Optical and Electron Microscopy Cellular Imaging

W. LiuB. NaydenovS. ChakraborttyB. WuenschK. Hübner  et al.

Nano Letters. 2016. DOI : 10.1021/acs.nanolett.6b02456.

SOFI Simulation Tool: A Software Package for Simulating and Testing Super-Resolution Optical Fluctuation Imaging

A. GirsaultT. LukesA. SharipovS. GeissbuehlerM. Leutenegger  et al.

PloS One. 2016. DOI : 10.1371/journal.pone.0161602.

2015

Combined Optical Coherence and Fluorescence Microscopy to assess dynamics and specificity of pancreatic beta-cell tracers

C. BerclazC. PacheA. BouwensD. P. SzlagA. Lopez  et al.

Scientific Reports. 2015. DOI : 10.1038/srep10385.

2014

IMAGING White-light diffraction tomography

A. BouwensT. Lasser

Nature Photonics. 2014. DOI : 10.1038/nphoton.2014.44.

Optical coherence correlation spectroscopy (OCCS)

S. BroilletA. SatoS. GeissbühlerC. PacheA. Bouwens  et al.

Optics Express. 2014. DOI : 10.1364/OE.22.000782.

Quantitative cerebral blood flow imaging with extended-focus optical coherence microscopy

A. BouwensT. BolmontD. P. SzlagC. BerclazT. Lasser

Optics Letters. 2014. DOI : 10.1364/OL.39.000037.

Live-cell multiplane three-dimensional super-resolution optical fluctuation imaging

S. GeissbuehlerA. SharipovA. GodinatN. L. BocchioP. A. Sandoz  et al.

Nature Communications. 2014. DOI : 10.1038/ncomms6830.

Visible light optical coherence correlation spectroscopy

S. BroilletD. P. SzlagA. BouwensL. MauriziH. Hofmann  et al.

Optics Express. 2014. DOI : 10.1364/OE.22.021944.

2013

Multiplane 3D superresolution optical fluctuation imaging

S. GeissbuehlerA. SharipovA. GodinatN. BocchioE. Dubikovskaya  et al.

arXiv. 2013.

How to display data by color schemes compatible with red-green color perception deficiencies

M. GeissbuehlerT. Lasser

Optics Express. 2013. DOI : 10.1364/OE.21.009862.

HILBERT TRANSFORM RELATIONS IN FREQUENCY-DOMAIN OPTICAL-COHERENCE TOMOGRAPHIC IMAGING

C. S. SeelamantulaT. Lasser

Journal of the Indian Institute of Science. 2013.

Quantitative lateral and axial flow imaging with optical coherence microscopy and tomography

A. BouwensD. P. SzlagM. SzkulmowskiT. BolmontM. Wojtkowski  et al.

Optics Express. 2013. DOI : 10.1364/OE.21.017711.

2012

Label-free imaging of cerebral β-amyloidosis with extended-focus optical coherence microscopy

T. BolmontA. BouwensC. PacheM. DimitrovC. Berclaz  et al.

The Journal of neuroscience. 2012. DOI : 10.1523/JNEUROSCI.0925-12.2012.

Assessment of transferrin recycling by Triplet Lifetime Imaging in living cells

M. GeissbuehlerZ. KadlecovaH.-A. KlokT. Lasser

Biomedical Optics Express. 2012. DOI : 10.1364/BOE.3.002526.

Diabetes imaging — quantitative assessment of islets of Langerhans distribution in murine pancreas using extended-focus optical coherence microscopy

C. BerclazJ. GoulleyM. VilligerA. BouwensE. Martin-williams  et al.

Biomedical Optics Express. 2012. DOI : 10.1364/BOE.3.001365.

Fluorescence correlation spectroscopy with a total internal reflection fluorescence STED microscope (TIRF-STED-FCS)

M. LeuteneggerC. RingemannT. LasserS. W. HellC. Eggeling

Optics Express. 2012. DOI : 10.1364/OE.20.005243.

Fast three-dimensional imaging of gold nanoparticles in living cells with photothermal optical lock-in Optical Coherence Microscopy

C. PacheN. L. BocchioA. BouwensM. VilligerC. Berclaz  et al.

Optics Express. 2012. DOI : 10.1364/OE.20.021385.

Zero-crossing approach to high-resolution reconstruction in frequency-domain optical-coherence tomography

S. R. KrishnanC. S. SeelamantulaA. BouwensM. LeuteneggerT. Lasser

Journal of the Optical Society of America A: Optics, Image Science and Vision. 2012. DOI : 10.1364/JOSAA.29.002080.

Nonlinear Correlation Spectroscopy (NLCS)

M. GeissbuehlerL. BonacinaV. ShcheslavskiyN. BocchioS. Geissbuehler  et al.

Nano Letters. 2012. DOI : 10.1021/nl300070n.

Mapping molecular statistics with balanced super-resolution optical fluctuation imaging (bSOFI)

S. GeissbuehlerN. L. BocchioC. DellagiacomaC. BerclazM. Leutenegger  et al.

Optical Nanoscopy. 2012. DOI : 10.1186/2192-2853-1-4.

2011

Real-time full field laser Doppler imaging

M. LeuteneggerE. Martin-WilliamsP. HarbiT. ThacherW. Raffoul  et al.

Biomedical Optics Express. 2011. DOI : 10.1364/BOE.2.001470.

Comparison between SOFI and STORM

S. GeissbühlerC. DellagiacomaT. Lasser

Biomedical Optics Express. 2011. DOI : 10.1364/BOE.2.000408.

2010

Towards high resolution optical imaging of beta cells in vivo

M. VilligerJ. GoulleyE. Martin-WilliamsA. Grapin-BottonT. Lasser

Current Pharmaceutical Design. 2010. DOI : 10.2174/138161210791164153.

Targeted Photoswitchable Probe for Nanoscopy of Biological Structures

C. DellagiacomaG. LukinaviciusN. BocchioS. BanalaS. Geissbühler  et al.

Chembiochem. 2010. DOI : 10.1002/cbic.201000189.

Transient State Monitoring by Total Internal Reflection Fluorescence Microscopy

T. SpielmannH. BlomM. GeissbuehlerT. LasserJ. Widengren

The Journal of Physical Chemistry B. 2010. DOI : 10.1021/jp911034v.

Dark-field optical coherence microscopy

M. VilligerC. PacheT. Lasser

Optics Letters. 2010. DOI : 10.1364/OL.35.003489.

Three-dimensional nano-localization of single fluorescent emitters

I. MärkiN. BocchioS. GeissbühlerF. AguetA. Bilenca  et al.

Optics Express. 2010. DOI : 10.1364/OE.18.020263.

Image formation and tomogram reconstruction in optical coherence microscopy

M. VilligerT. Lasser

Journal of the Optical Society of America A: Optics, Image Science and Vision. 2010. DOI : 10.1364/JOSAA.27.002216.

Triplet imaging of oxygen consumption during the contraction of a single smooth muscle cell (A7r5)

M. GeissbuehlerT. SpielmannA. FormeyI. MärkiM. Leutenegger  et al.

Biophysical Journal. 2010. DOI : 10.1016/j.bpj.2009.10.006.

2009

Imaging of G protein-coupled receptors in solid-supported planar lipid membranes

M. LeuteneggerT. LasserE.-K. SinnerR. Robelek

Biointerphases. 2009. DOI : 10.1116/1.3054189.

In vivo imaging of murine endocrine islets of Langerhans with extended-focus optical coherence microscopy

J. GoulleyM. VilligerM. FriedrichA. Grapin-BottonP. Meda  et al.

Diabetologia. 2009. DOI : 10.1007/s00125-009-1383-y.

High volume confinement in two-photon total-internal- reflection fluorescence correlation spectroscopy

D. IvanovV. ShcheslavskiyI. MärkiM. LeuteneggerT. Lasser

Applied Physics Letters. 2009. DOI : 10.1063/1.3077309.

Direct Observation of Transitions between Surface-Dominated and Bulk Diffusion Regimes in Nanochannels

N. F. Y. DurandC. DellagiacomaR. GoetschmannA. BertschI. Maerki  et al.

Analytical Chemistry. 2009. DOI : 10.1021/ac900617b.

Information Limits of Optical Coherence Imaging Through Scattering Media

A. BilencaT. LasserB. E. BoumaR. A. LeitgebG. J. Tearney

Ieee Photonics Journal. 2009. DOI : 10.1109/JPHOT.2009.2026911.

Laser Doppler imaging for intraoperative human brain mapping

A. RaabeD. Van De VilleM. LeuteneggerA. SzelényiE. Hattingen  et al.

NeuroImage. 2009. DOI : 10.1016/j.neuroimage.2008.10.049.

Super-resolution orientation estimation and localization of fluorescent dipoles using 3-D steerable filters

F. AguetS. GeissbühlerI. MärkiT. LasserM. Unser

Optics Express. 2009. DOI : 10.1364/OE.17.006829.

2008

Complex ambiguity-free Fourier domain optical coherence tomography through transverse scanning

R. A. LeitgebR. MichaelyT. LasserS. C. Sekhar

The Virtual Journal of Biomedical Optics. 2008.

Detection efficiency in total internal reflection fluorescence microscopy

M. LeuteneggerT. Lasser

Optics Express. 2008. DOI : 10.1364/OE.16.008519.

2007

Image formation in fluorescence coherence-gated imaging through scattering media

A. BilencaT. LasserA. OzcanR. A. LeitgebB. E. Bouma  et al.

Optics Express. 2007. DOI : 10.1364/OE.15.002810.

Resonant Doppler flow imaging and optical vivisection of retinal blood vessels

A. H. BachmannM. L. VilligerC. BlatterT. LasserR. A. Leitgeb

Optics Express. 2007. DOI : 10.1364/OE.15.000408.

Vectorial retinal blood flow and optical vessel vivisection for 3D angiography with high resolution resonant Doppler OCT

R. A. LeitgebR. MichaelyA. H. BachmannM. VilligerC. Blatter  et al.

Investigative Ophthalmology & Visual Science. 2007.

Field confinement with aberration correction for solid immersion lens based fluorescence correlation spectroscopy

R. RaoJ. MiticA. SerovR. A. LeitgebT. Lasser

Optics Communications. 2007. DOI : 10.1016/j.optcom.2006.10.044.

Dynamic disorder in horseradish peroxidase observed with total internal reflection fluorescence correlation spectroscopy

K. HasslerP. RiglerH. BlomR. RiglerJ. Widengren  et al.

Optics Express. 2007. DOI : 10.1364/OE.15.005366.

Dual-beam heterodyne Fourier domain optical coherence tomography

A. H. BachmannR. MichaelyT. LasserR. A. Leitgeb

Optics Express. 2007. DOI : 10.1364/OE.15.009254.

In vitro synthesis of GPCRs in a solid supported planar lipid membrane system

R. RobelekM. LeuteneggerB. WiltschiE. S. LemkeD. Oesterhelt  et al.

Biophysical Journal. 2007.

Complex Ambiguity-Free Fourier Domain Optical Coherence Tomography through Transverse Scanning

R. A. LeitgebR. MichaelyT. LasserS. C. Sekhar

Optics Letters. 2007. DOI : 10.1364/OL.32.003453.

Vectorial reconstruction of retinal blood flow in three dimensions measured with high resolution resonant Doppler Fourier domain optical coherence tomography

R. MichaelyA. H. BachmannM. L. VilligerC. BlatterT. Lasser  et al.

Journal of Biomedical Optics (JBO). 2007. DOI : 10.1117/1.2771553.

2006

Confining the sampling volume for Fluorescence Correlation Spectroscopy using a sub-wavelength sized aperture

M. LeuteneggerM. GöschA. PerentesP. HoffmannO. J. F. Martin  et al.

Optics Express. 2006. DOI : 10.1364/OPEX.14.000956.

Fast focus field calculations

M. LeuteneggerR. RaoR. A. LeitgebT. Lasser

Optics Express. 2006. DOI : 10.1364/OE.14.011277.

Heterodyne Fourier domain optical coherence tomography for full range probing with high axial resolution

A. H. BachmannR. A. LeitgebT. Lasser

Optics Express. 2006. DOI : 10.1364/OE.14.001487.

Stochastic Approach to Data Analysis in Fluorescence Correlation Spectroscopy

R. RaoR. LangojuM. GöschP. RiglerA. Serov  et al.

The Journal of Physical Chemistry A. 2006. DOI : 10.1021/jp055763t.

An all-fiber Pr/Yb-doped up-conversion laser in different laser operation modes

M. ZellerH. G. LimbergerT. Lasser

Tm-Technisches Messen. 2006. DOI : 10.1524/teme.2006.73.3.166.

Extended focus depth for Fourier domain optical coherence microscopy

R. A. LeitgebM. VilligerA. H. BachmannL. SteinmannT. Lasser

Optics Letters. 2006. DOI : 10.1364/OL.31.002450.

Dual-color total internal reflection fluorescence cross- correlation spectroscopy

M. LeuteneggerH. BlomJ. WidengrenC. EggelingM. Gösch  et al.

Journal of Biomedical Optics (JBO). 2006. DOI : 10.1117/1.2221714.

Simultaneous Multicolor Fluorescence Cross-Correlation Spectroscopy to Detect Higher Order Molecular Interactions Using Single Wavelength Laser Excitation

L. C. HwangM. GöschT. LasserT. Wohland

Biophysical Journal. 2006. DOI : 10.1529/biophysj.105.074120.

Prism-based multicolor fluorescence correlation spectrometer

L. C. HwangM. LeuteneggerM. GöschT. LasserP. Rigler  et al.

Optics Letters. 2006. DOI : 10.1364/OL.31.001310.

2005

Fabrication of arrays of sub-wavelength nano-apertures in an optically thick gold layer on glass slides for optical studies

A. PerentesI. UtkeB. DwirM. LeuteneggerT. Lasser  et al.

Nanotechnology. 2005. DOI : 10.1088/0957-4484/16/5/025.

Total internal reflection fluorescence correlation spectroscopy (TIR-FCS) with low background and high count-rate per molecule

K. HasslerM. LeuteneggerP. RiglerR. RaoR. Rigler  et al.

Optics Express. 2005. DOI : 10.1364/OPEX.13.007415.

Time-resolved Hadamard fluorescence imaging

K. HasslerT. AnhutT. Lasser

Applied Optics. 2005. DOI : 10.1364/AO.44.007564.

Parallel dual-color fluorescence cross-correlation spectroscopy using diffractive optical elements

M. GöschH. BlomS. AndereggK. KornP. Thyberg  et al.

Journal of Biomedical Optics (JBO). 2005. DOI : 10.1117/1.2080707.

Speckle statistics in optical coherence tomography

B. KaramataK. HasslerM. LaubscherT. Lasser

Journal of the Optical Society of America A: Optics, Image Science and Vision. 2005. DOI : 10.1364/JOSAA.22.000593.

Full-field laser Doppler perfusion imaging and monitoring with an intelligent CMOS camera

A. SerovB. SteinacherT. Lasser

Optics Express. 2005. DOI : 10.1364/OPEX.13.003681.

Ultrasensitive reporter protein detection in genetically engineered bacteria

M. WellsM. GöschR. RiglerH. HarmsT. Lasser  et al.

Analytical Chemistry. 2005. DOI : 10.1021/ac048127k.

High count rates with total internal reflection fluorescence correlation spectroscopy

K. HasslerT. AnhutR. RiglerM. GöschT. Lasser

Biophysical Journal. 2005. DOI : 10.1529/biophysj.104.053884.

High-speed laser Doppler perfusion imaging using an integrating CMOS image sensor

A. SerovT. Lasser

Optics Express. 2005. DOI : 10.1364/OPEX.13.006416.

Multiple scattering in optical coherence tomography. II. Experimental and theoretical investigation of cross talk in wide-field optical coherence tomography

B. KaramataM. LeuteneggerM. LaubscherS. BourquinT. Lasser  et al.

Journal of the Optical Society of America A: Optics, Image Science and Vision. 2005. DOI : 10.1364/JOSAA.22.001380.

Multiple scattering in optical coherence tomography. I. Investigation and modeling

B. KaramataM. LaubscherM. LeuteneggerS. BourquinT. Lasser  et al.

Journal of the Optical Society of America A: Optics, Image Science and Vision. 2005. DOI : 10.1364/JOSAA.22.001369.

UV-induced index changes in undoped fluoride glass

M. ZellerT. LasserH. G. LimbergerG. Maze

Journal of Lightwave Technology. 2005. DOI : 10.1109/JLT.2004.841781.

2004

Spectroscopic optical coherence tomography based on wavelength de-multiplexing and smart pixel array detection

M. LaubscherS. BourquinL. FroehlyB. KaramataT. Lasser

Optics Communications. 2004. DOI : 10.1016/j.optcom.2004.03.084.

High light field confinement for Fluorescence Correlation Spectroscopy using a Solid Immersion Lens

A. SerovR. RaoM. GoeschT. AnhutD. Martin  et al.

Biosensors and Bioelectronics. 2004. DOI : 10.1016/j.bios.2004.02.028.

Spatially incoherent illumination as a mechanism for cross-talk suppression in wide-field optical coherence tomography

B. KaramataP. LambeletM. LaubscherR. P. SalatheT. Lasser

Optics Letters. 2004. DOI : 10.1364/OL.29.000736.

Non equilibrium catalysis of single enzyme molecules

R. RiglerL. EdmanS. WennmalmM. LeuteneggerT. Anhut  et al.

Abstracts of Papers of the American Chemical Society. 2004.

Parallel single molecule detection with a fully integrated single-photon 2X2 CMOS detector array

M. GoschA. SerovT. AnhutT. LasserA. Rochas  et al.

Journal of Biomedical Optics (JBO). 2004. DOI : 10.1117/1.1781668.

2003

High-speed femtosecond pump probe spectroscopy with a smart pixel detector array

S. BourquinR. P. PrasankumarF. X. KärtnerJ. G. FujimotoT. Lasser  et al.

Optics Letters. 2003. DOI : 10.1364/OL.28.001588.

Tunable Pr3+-Yb3+-doped all-fiber upconversion laser

M. ZellerH. G. LimbergerT. Lasser

Ieee Photonics Technology Letters. 2003. DOI : 10.1109/LPT.2002.806852.

Multiplexed 3D imaging using wavelength encoded spectral interferometry: a proof of principle

L. FroehlyS. N. MartinT. LasserC. DepeursingeF. Lang

Optics Communications. 2003. DOI : 10.1016/S0030-4018(03)01611-0.

Resonator stability subject to dynamic random-tilt aberration

M. O. HonglerT. LasserG. Evequoz

Journal of the Optical Society of America A: Optics, Image Science and Vision. 2003. DOI : 10.1364/JOSAA.20.000151.

First fully integrated 2-D array of single-photon detectors in standard CMOS technology

A. RochasM. GoschA. SerovP. A. BesseR. S. Popovic  et al.

Ieee Photonics Technology Letters. 2003. DOI : 10.1109/LPT.2003.813387.

Self-referenced method for optical path difference calibration in low-coherence interferometry

M. LaubscherL. FroehlyB. KaramataR. P. SalathéT. Lasser

Optics Letters. 2003. DOI : 10.1364/OL.28.002476.

Multiplexed 3D imaging using wavelength encoded spectral interferometry: a proof of principle (vol 222, pg 127, 2003)

L. FroehlyS. N. MartinT. LasserC. DepeursingeF. Lang

Optics Communications. 2003. DOI : 10.1016/S0030-4018(03)01730-9.

Optical sectioning in wide-field microscopy obtained by dynamic structured light illumination and detection based on a smart pixel detector array

J. MiticT. AnhutM. MeierM. DucrosA. Serov  et al.

Optics Letters. 2003. DOI : 10.1364/OL.28.000698.

Optical coherence tomography - principles and applications

A. F. FercherW. DrexlerC. K. HitzenbergerT. Lasser

Reports on Progress in Physics. 2003. DOI : 10.1088/0034-4885/66/2/204.

2002

Parallel optical coherence tomography in scattering samples using a two-dimensional smart-pixel detector array

M. DucrosM. LaubscherB. KaramataS. BourquinT. Lasser  et al.

Optics Communications. 2002. DOI : 10.1016/S0030-4018(02)01073-8.

Dispersion compensation for optical coherence tomography depth-scan signals by a numerical technique

A. F. FercherC. K. HitzenbergerM. StickerR. ZawadzkiB. Karamata  et al.

Optics Communications. 2002. DOI : 10.1016/S0030-4018(02)01137-9.

Video-rate three-dimensional optical coherence tomography

M. LaubscherM. DucrosB. KaramataT. LasserR. Salathe

Optics Express. 2002. DOI : 10.1364/OE.10.000429.

2001

Numerical dispersion compensation for Partial Coherence Interferometry and Optical Coherence Tomography

A. F. FercherC. K. HitzenbergerM. StickerR. ZawadzkiB. Karamata  et al.

Optics Express. 2001. DOI : 10.1364/OE.9.000610.

2000

Actively mode-locked visible upconversion fiber laser

D. M. CostantiniH. G. LimbergerT. LasserC. A. P. MullerH. Zellmer  et al.

Optics Letters. 2000. DOI : 10.1364/OL.25.001445.

Corneal morphology in vitro after superficial keractomy with Q-switched Er: YSSG and free-tunning ER: YAG lasers

J. KampmeierD. RussS. SchaferT. Lasser

Journal of Refractive Surgery. 2000. DOI : 10.3928/1081-597X-20000501-08.

Conference Papers

2017

Combining PALM and SOFI for quantitative imaging of focal adhesions in living cells

H. DeschoutT. LukesA. SharipovL. FelettiT. Lasser  et al.

2017. SPIE Photonics West, San Francisco, 27 January-2 February 2017. DOI : 10.1117/12.2252865.

2016

Three dimensional time lapse imaging of live cell mitochondria with photothermal optical lock-in optical coherence microscopy (Conference Presentation)

M. SisonS. ChakraborttyJ. ExtermannA. NahasC. Pache  et al.

2016. Conference on Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XX, San Francisco, CA, FEB 15-17, 2016. DOI : 10.1117/12.2214761.

Imaging of the stroke-related changes in the vascular system of the mouse brain with the use of extended focus Optical Coherence Microscopy

S. TamborskiH. C. LyuD. BukowskaH. DolezyczekG. Wilczynski  et al.

2016. SPIE Photonics West, BiOS, San Francisco, January 13-18, 2016. DOI : 10.1117/12.2214779.

2012

Real-time Full Field Laser Doppler Imaging

M. LeuteneggerP. HarbiT. ThacherW. RaffoulT. Lasser

2012. 10th International Conference on Vibration Measurements by Laser and Noncontact Techniques - AIVELA', u'10th International Conference on Vibration Measurements by Laser and Noncontact Techniques - AIVELA, Ancona, Italy, June 26-29, 2012. p. 282 - 286. DOI : 10.1063/1.4730568.

Triplet imaging of oxygen consumption during the contraction of a single smooth muscle cell (A7r5)

M. GeissbühlerT. SpielmannA. Formey de Saint LouventI. MärkiM. Leutenegger  et al.

2012. Conference of international society on oxygen transport to tissue, Monte Verità, Ascona, Switzerland, July 18-23, 2010. p. 263 - 268. DOI : 10.1007/978-1-4614-1566-4_39.

2010

Dark-field optical coherence microscopy

C. PacheM. VilligerT. Lasser

2010. BIOS 2010, coherence domain optical methods and optical coherence tomography in biomedicine XIV, San Francisco, USA, January 23-28, 2010. DOI : 10.1117/12.842848.

Super-resolved position and orientation estimation of fluorescent dipoles using 3-D steerable filters

S. GeissbühlerF. AguetI. MärkiT. Lasser

2010. BiOS 2010 - Single Molecule Spectroscopy and Imaging III, San Francisco, January 23-28, 2010. DOI : 10.1117/12.841783.

Live in vivo imaging of Langerhans islets in normal and diabetic mice by extended focus optical coherence microscopy

J. GoulleyM. VilligerC. BerclazP. MedaA. Grapin-Botton  et al.

2010. 46th Annual Meeting of the European-Association-for-the- Study-of-Diabetes (EASD), Stockholm, SWEDEN, Sep 20-24, 2010. p. S194 - S194.

Coherent transfer functions and extended depth of field

M. VilligerC. PacheR. A. LeitgebT. Lasser

2010. Coherence Domain Optical Methods and Optical Coherence Tomography in Biomedicine XIV, San Francisco, CA, USA, January 23-28, 2010. DOI : 10.1117/12.840819.

2009

Steerable filters for orientation estimation and localization of fluorescent dipoles

F. AguetS. GeissbühlerI. MärkiT. LasserM. Unser

2009. IEEE International Symposium on Biomedical Imaging: From Nano to Macro, Boston, Massachusetts, June 28 - July 1, 2009. p. 1166 - 1169. DOI : 10.1109/ISBI.2009.5193265.

Three-Dimensional Localization of Nano-Emitters with Nanometer-Level Precision

I. MärkiS. GeissbühlerT. LasserF. Aguet

2009. Novel Techniques in Microscopy (NTM), Vancouver, CA, April 30, 2009.

In vivo imaging of pancreatic endocrine islets

M. VilligerJ. GoulleyC. PacheM. FriedrichA. Grapin-Botton  et al.

2009. ECBO 2009, Optical Coherence Tomography and Coherence Techniques IV, Munich, Germany, June 14-18 2009. DOI : 10.1117/12.831864.

Three-Dimensional Localization of Nano-Emitters with Nanometer-Level Precision

I. MärkiS. GeissbühlerF. AguetT. Lasser

2009. OSA Optics & Photonics Congress, Advances in Imaging, Vancouver, CA, April 26-30, 2009. DOI : 10.1364/NTM.2009.NMB3.

Super-resolved position and orientation of fluorescent dipoles

F. AguetS. GeissbühlerI. MärkiT. LasserM. Unser

2009. ECBO 2009, Advanced Microscopy Techniques, Munich, Germany, June 14-18 2009. DOI : 10.1117/12.831488.

High volume confinement in two-photon fluorescence correlation spectroscopy with radially polarized light

D. IvanovV. ShcheslavskiyI. MärkiM. LeuteneggerT. Lasser

2009. BIOS, San Jose, CA, USA, January 24, 2009. DOI : 10.1117/12.807596.

See the Brain at Work—Intraoperative Laser Doppler Functional Brain Imaging

E. J. Martin-WilliamsA. RaabeD. Van De VilleM. LeuteneggerA. Szelenyi  et al.

2009. ECBO 2009, Optical Coherence Tomography and Coherence Techniques IV, Munich, Germany, June 14-18 2009. DOI : 10.1117/12.831813.

2008

Imaging of G protein-coupled receptors in solid- supported planar membranes at the single molecule level

I. MärkiM. LeuteneggerM. GeissbuehlerR. RobelekE. Sinner  et al.

2008. BiOS 2008, San Jose, CA, USA, 19-24 Jan 2008. DOI : 10.1117/12.763088.

Extended focus optical coherence microscopy and fluorescence lifetime imaging

M. L. VilligerC. BlatterA. H. BachmannT. LasserR. A. Leitgeb

2008. BiOS 2008, San Jose, CA, USA, 19-24 Jan 2008. DOI : 10.1117/12.763163.

Phase manipulation without phase shifter for complex FDOCT signal reconstruction and resonant Doppler imaging

R. A. LeitgebR. MichaelyA. H. BachmannM. L. VilligerC. Blatter  et al.

2008. BiOS 2008, San Jose, CA, USA, 19-24 Jan 2008.

Fast focus field calculations

M. LeuteneggerM. GeissbuehlerI. MärkiR. A. LeitgebT. Lasser

2008. BiOS 2008, San Jose, CA, USA, 19-24 Jan 2008. DOI : 10.1117/12.763188.

Frequency encoded assessment of retinal physiology

R. A. LeitgebR. MichaelyA. BachmannT. LasserC. Blatter

2008. 18th Conference on Ophthalmic Technologies, San Jose, CA, Jan 19-21, 2008. DOI : 10.1117/12.764330.

k-Microscopy: resolution beyond the diffraction limit

M. GeissbuehlerT. LasserR. A. Leitgeb

2008. BiOS 2008, San Jose, CA, USA, 19-24 Jan 2008. DOI : 10.1117/12.763191.

2007

Measurement of retinal physiology using functional Fourier domain OCT concepts

R. A. LeitgebA. H. BachmannM. L. VilligerR. MichaelyC. Blatter  et al.

2007. BiOS 2007, San Jose, CA, USA, Jan 2007. DOI : 10.1117/12.702232.

Intensity based quantification of fast retinal blood flow in 3D via high resolution resonant Doppler spectral OCT

R. MichaelyA. H. BachmannM. L. VilligerC. BlatterT. Lasser  et al.

2007. Conference on Optical Coherence Tomography and Coherence Techniques III, Munich, GERMANY, Jun 00-19, 2007. DOI : 10.1117/12.728473.

Extended focus Fourier domain optical coherence microscopy assists developmental biology

M. L. VilligerM. BeleutC. BriskenT. LasserR. A. Leitgeb

2007. Optical Coherence Tomography and Coherence Techniques III, Munich, Germany, Sunday 17 June 2007. DOI : 10.1117/12.728370.

2006

Combined laser Doppler and laser speckle imaging for real- time blood blow measurements

G. L. CotéA. V. PriezzhevA. SerovT. Lasser

2006. BiOS 2006, San Jose, CA, USA, Jan 2006. DOI : 10.1117/12.646012.

Laser Doppler blood-flow imaging combined with topographical imaging of the sample

F. S. AzarD. N. MetaxasR. MichaelyA. SerovP. Jacquot  et al.

2006. BiOS 2006, San Jose, CA, USA, Jan 2006. DOI : 10.1117/12.645200.

High-speed laser Doppler imaging of blood flow in biological tissue

V. V. TuchinA. SerovT. Lasser

2006. Saratov Fall Meeting 2005, Saratov, Russia, 27-30 Sep 2005. DOI : 10.1117/12.696924.

Full-field high-speed laser Doppler imaging system for blood-flow measurements

G. E. CohnW. S. GrundfestD. A. BenaronT. Vo-DinhA. Serov  et al.

2006. BiOS 2006, San Jose, CA, USA, Jan 2006. DOI : 10.1117/12.645205.

Complex unltrahigh resolution Fourier domain optical coherence tomography

V. V. TuchinJ. A. IzattJ. G. FujimotoA. H. BachmannT. Lasser  et al.

2006. BiOS 2006, San Jose, CA, USA, Jan 2006. DOI : 10.1117/12.648862.

Reviews

2015

Diffraction-unlimited imaging: from pretty pictures to hard numbers

W. VandenbergM. LeuteneggerT. LasserJ. HofkensP. Dedecker

Cell And Tissue Research. 2015. DOI : 10.1007/s00441-014-2109-0.

Books

2014

Optical microscopy for biology and life sciences

M. LeuteneggerT. Lasser

Lausanne: Laboratoire d'Optique Biomédicale, EPFL, 2014.

Theses

2019

Optical projection tomography for whole organ imaging

D. Nguyen / T. LasserD. N. A. Van De Ville (Dir.)

Lausanne, EPFL, 2019. DOI : 10.5075/epfl-thesis-9094.

2017

Coherent Imaging of Cellular Dynamics

M. Sison / T. Lasser (Dir.)

Lausanne, EPFL, 2017. DOI : 10.5075/epfl-thesis-8202.

Coherent imaging from bacteria to multicellular organisms

S. Coquoz / T. LasserM. Leutenegger (Dir.)

Lausanne, EPFL, 2017. DOI : 10.5075/epfl-thesis-7857.

Multi-plane super-resolution microscopy

A. Sharipov / T. LasserM. Leutenegger (Dir.)

Lausanne, EPFL, 2017. DOI : 10.5075/epfl-thesis-7570.

Super-resolution microscopy live cell imaging and image analysis

T. Lukes / M. KlímaK. FliegelT. Lasser (Dir.)

Czech Technical University in Prague, 2017.

2015

Structural and Functional Imaging of Pancreatic Islets using Optical Coherence Microscopy

C. Berclaz / T. LasserA. Grapin-Botton (Dir.)

Lausanne, EPFL, 2015. DOI : 10.5075/epfl-thesis-6560.

2014

Optical Coherence Correlation Spectroscopy

S. Broillet / T. LasserM. Leutenegger (Dir.)

Lausanne, EPFL, 2014. DOI : 10.5075/epfl-thesis-6342.

2013

Functional and Structural Imaging with Optical Coherence Microscopy : Principles & Applications

A. Bouwens / T. LasserM. Chergui (Dir.)

Lausanne, EPFL, 2013. DOI : 10.5075/epfl-thesis-5972.

Structural and Functional Stochastic Super-Resolution Microscopy

S. Geissbühler / T. LasserM. Leutenegger (Dir.)

Lausanne, EPFL, 2013. DOI : 10.5075/epfl-thesis-5826.

2012

Contrast Enhancement in Optical Coherence Microscopy

C. Pache / T. Lasser (Dir.)

Lausanne, EPFL, 2012. DOI : 10.5075/epfl-thesis-5566.

2011

Novel Concepts for Functional High Resolution Microscopy

M. Geissbühler / T. Lasser (Dir.)

Lausanne, EPFL, 2011. DOI : 10.5075/epfl-thesis-5177.

Single Molecule Sensing

C. Dellagiacoma / T. Lasser (Dir.)

Lausanne, EPFL, 2011. DOI : 10.5075/epfl-thesis-5155.

2010

Biomolecular Diffusion in Nanofluidics

N. Durand / P. RenaudT. Lasser (Dir.)

Lausanne, EPFL, 2010. DOI : 10.5075/epfl-thesis-4736.

Extended Focus Optical Coherence Microscopy : Theory and Application

M. Villiger / T. LasserR. Leitgeb (Dir.)

Lausanne, EPFL, 2010. DOI : 10.5075/epfl-thesis-4787.

2008

Tomographie en cohérence optique dans le domaine de Fourier appliquée aux tissus humains

R. Michaely / T. Lasser (Dir.)

Lausanne, EPFL, 2008. DOI : 10.5075/epfl-thesis-4131.

2007

Phase-locked Fourier domain optical coherence tomography

A. H. Bachmann / T. LasserR. Leitgeb (Dir.)

Lausanne, EPFL, 2007. DOI : 10.5075/epfl-thesis-3847.

Single molecule detection on surfaces

M. Leutenegger / T. Lasser (Dir.)

Lausanne, EPFL, 2007. DOI : 10.5075/epfl-thesis-3854.

2006

Fluorescence correlation spectroscopy : simulations and bio-chemical applications based on solid immersion lens concept

R. Rao / T. Lasser (Dir.)

Lausanne, EPFL, 2006. DOI : 10.5075/epfl-thesis-3697.

Single molecule detection and fluorescence correlation spectroscopy on surfaces

K. Hassler / T. Lasser (Dir.)

Lausanne, EPFL, 2006. DOI : 10.5075/epfl-thesis-3433.

2004

Photosensitivity and bragg grating technology for upconversion all-fiber lasers

M. Zeller / T. Lasser (Dir.)

Lausanne, EPFL, 2004. DOI : 10.5075/epfl-thesis-2921.

Multiple scattering in wide-field optical coherence tomography

B. Karamata / T. Lasser (Dir.)

Lausanne, EPFL, 2004. DOI : 10.5075/epfl-thesis-3001.

Innovative experimental concepts for optical coherence tomography

M. Laubscher / T. Lasser (Dir.)

Lausanne, EPFL, 2004. DOI : 10.5075/epfl-thesis-2954.

Application of CMOS image sensors in optical sectioning and polarization microscopy

J. Mitic / T. Lasser (Dir.)

Lausanne, EPFL, 2004. DOI : 10.5075/epfl-thesis-3101.

2001

Optical spectral probing for epithelial tissue characterisation

P. Thueler / T. Lasser (Dir.)

Lausanne, EPFL, 2001. DOI : 10.5075/epfl-thesis-2241.

Optische Augenlängenmessung für klinische Anwendungen

B. Möller / T. Lasser (Dir.)

Lausanne, EPFL, 2001. DOI : 10.5075/epfl-thesis-2270.

Book Chapters

2016

Cross Talk in Full-Field Optical Coherence Tomography

B. KaramataM. LeuteneggerT. Lasser

Handbook of Full-Field Optical Coherence Microscopy: Technology and Applications; Pan Stanford Publishing, 2016. p. 131 - 182.

2015

OCM with Engineered Wavefront

R. A. LeitgebT. LasserM. Villiger

Optical Coherence Tomography; Springer, 2015. p. 913 - 940.

2007

Single molecule detection at surfaces

M. LeuteneggerK. HasslerP. RiglerA. BilencaT. Lasser

New Approaches in Biomedical Spectroscopy; American Chemical Society, 2007. p. 1 - 18.

Working Papers

2011

Nonlinear Correlation Spectroscopy (NLCS) Theory

M. GeissbuehlerS. GeissbuehlerT. Lasser

2011

Posters

2011

Assessing the cellular uptake pathway for poly-Lysine analogues using triplet lifetime imaging

M. GeissbuehlerZ. KadlecovaI. MärkiM. MatasciD. Van De Ville  et al.

Biophysical Society 55th Annual Meeting, Baltimore, Maryland, USA, March 5-9, 2011.

2010

Measurement of the coherent transfer function

M. VilligerC. PacheT. Lasser

Coherence Domain Optical Methods and Optical Coherence Tomography in Biomedicine XIV, San Francisco, CA, USA, January 23-28, 2010.

2009

In Vivo extended focus Optical Coherence Microscopy of endocrine islets of Langerhans in mice

M. VilligerJ. GoulleyM. FriedrichA. Grapin-BottonP. Meda  et al.

Biomedical Photonics Network day 2009 (BMPN), Fisba Optik AG, St. Gallen, Switzerland, June 10 2009.

Engineering of Extended Focii for Optical Coherence Microscopy

C. PacheM. VilligerS. RutishauserR. A. LeitgebT. Lasser

ECBO 2009, Optical Coherence Tomography and Coherence Techniques Posters, Munich, Germany, June 14-18 2009.

High-resolution imaging with simultaneous estimation of position and orientation of single molecules

S. GeissbühlerF. AguetI. MärkiT. LasserM. Unser

Biomedical Photonics Network day 2009 (BMPN), Fisba Optik AG, St. Gallen, Switzerland, June 10 2009.

Triplet imaging by modulated excitation

M. GeissbuehlerT. SpielmannI. MärkiA. FormeyB. Hinz  et al.

Biomedical Photonics Network day 2009 (BMPN), Fisba Optik AG, St. Gallen, Switzerland, June 10 2009.

Diffusion of Single Molecules in Nanochannels

C. DellagiacomaN. F. Y. DurandR. GoetschmannI. MaerkiA. Bertsch  et al.

Biomedical Photonics Network day 2009 (BMPN), Fisba Optik AG, St. Gallen, Switzerland, June 10 2009.

Three-dimensional Nano-Localization of Fluroescent Emitters

I. MärkiN. BocchioS. GeissgühlerF. AguetT. Lasser

International Workshop on "Single Molecule Spectroscopy and Ultra Sensitive Analysis in the Life Sciences", Berlin, Germany, September 15-18, 2009.

Diffusion of Single Molecules in Nanochannels

C. DellagiacomaN. F. Y. DurandR. GoetschmannI. MaerkiA. Bertsch  et al.

ECBO 2009, Advanced Microscopy Techniques Posters, Munich, Germany, June 14-18 2009.

2008

Fourier Domain Optical Coherence Microscopy with Extended Depth of Field

M. VilligerA. H. BachmannM. LeuteneggerL. SteinmannT. Lasser  et al.

BMPN DAY AT EPMT, Lausanne, Switzerland, June 4, 2008.

Triplet Imaging by Modulated Excitation

M. GeissbuehlerT. SpielmannI. MärkiA. FormeyA. Gautier  et al.

14th International Workshop on "Single Molecule Spectroscopy and Ultra Sensitive Analysis in the Life Sciences", Berlin-Adlershof, Germany, September 17-19, 2008.

Fast focus field calculations

M. LeuteneggerM. GeissbuehlerI. MärkiR. A. LeitgebT. Lasser

USGEB 2008 - Biology Meets Engineering, Lausanne, Switzerland, 6-7 Feb 2008.

Optical Investigation of Skin Morphology and Anatomy

R. MichaelyA. SerovR. LeitgebP. JacquotT. Lasser

BMPN DAY AT EPMT, Lausanne, Switzerland, June 4, 2008.

Single molecule imaging of odorant receptors in supported planar lipid membranes

I. MärkiM. LeuteneggerM. GeissbuehlerR. RobelekE. K. Sinner  et al.

BMPN DAY AT EPMT, Lausanne, Switzerland, June 4, 2008.

k-Microscopy: resolution beyond the diffraction limit

R. A. LeitgebM. GeissbuehlerT. Lasser

BiOS 2008, San Jose, CA, USA, 19-24 Jan 2008.

Imaging of G protein-coupled receptors in solid-supported planar membranes at the single molecule level

I. MärkiM. LeuteneggerM. GeissbuehlerR. RobelekE. Sinner  et al.

USGEB 2008 - Biology Meets Engineering, Lausanne, Switzerland, 6-7 Feb 2008.

Intraoperative functional brain imaging - hemodynamic response visualization using Laser Doppler

E. Martin-WilliamsD. Van De VilleA. LopezM. LeuteneggerR. Leitgeb  et al.

6th FENS Forum of European Neuroscience, organised by the Federation of European Neuroscience Societies, Geneva, Switzerland, July 12-16, 2008.

Optical Investigation of Skin Morphology and Anatomy

R. MichaelyA. SerovR. A. LeitgebP. JacquotT. Lasser

Annual meeting of the Biomedical Photonics Network, Lausanne, Switzerland, June 4, 2008.

Enhancement of extended depth of field by digital focusing

M. L. VilligerC. BlatterT. LasserR. A. Leitgeb

BiOS 2008, San Jose, CA, USA, 19-24 Jan 2008.

2007

Fourier Domain Optical Coherence Microscopy with extended depth of field

M. VilligerA. H. BachmannM. LeuteneggerL. SteinmannT. Lasser  et al.

Nanoscale Engineering of the Biointerface, Playa del Aro, Spain, 28 May-1 Jun 2007.

In vitro Synthesis of GPCRs in a Solid Supported Planar Lipid Membrane System

R. RobelekM. LeuteneggerB. WiltschiE. S. LemkerD. Oesterhelt  et al.

51th Annual Meeting of the Biophysical Society, Baltimore, Maryland, 3-7 Mar 2007.

Two color fluorescence correlation spectroscopy (FCS) and total internal reflection FCS

M. GeissbuehlerM. LeuteneggerI. MärkiH. BlomC. Eggeling  et al.

Nanoscale Engineering of the Biointerface, Playa del Aro, Spain, 28 May-1 Jun 2007.

Single molecule imaging of odorant receptors in supported planar lipid membranes

M. LeuteneggerR. RobelekE. SinnerT. Lasser

CHUV Research day 2007, Lausanne, Switzerland, 2007-02-01.

Single molecule imaging of odorant receptors in supported planar lipid membranes

M. LeuteneggerM. GeissbuehlerI. MärkiR. RobelekE. Sinner  et al.

Nanoscale Engineering of the Biointerface, Playa del Aro, Spain, 28 May-1 Jun 2007.

In vitro Synthesis of GPCRs in a Solid Supported Planar Lipid Membrane System

R. RobelekM. LeuteneggerB. WiltschiE. S. LemkerD. Oesterhelt  et al.

Biophysical Society - 51st Annual Meeting, Baltimore, Maryland, March 3-7, 2007.

Skin Morphology and Anatomy

R. MichaelyR. A. LeitgebT. Lasser

CHUV Research day 2007, Lausanne, Switzerland, 2007-02-01.

Single molecule imaging of odorant receptors in supported planar lipid membranes

R. RobelekM. LeuteneggerE. SinnerT. Lasser

Winterschool, Klosters, Switzerland, 2007-01-14.

2006

Single molecule imaging of odorant receptors in supported planar lipid membranes

M. LeuteneggerR. RobelekE. SinnerT. Lasser

EPFL Photonics day 2006, Lausanne, Switzerland, 2006-11-24.

Talks

2013

Optical Coherence Correlation Spectroscopy (OCCS)

S. BroilletS. GeissbühlerA. SatoC. PacheA. Bouwens  et al.

BIOS 2013: Single Molecule Spectroscopy and Superresolution Imaging VI, San Francisco, California, USA, February 2-7, 2013.

Three-dimensional Super-resolution Optical Fluctuation Imaging

M. LeuteneggerS. GeissbühlerN. L. BocchioC. BerclazT. Lasser

Focus on Microscopy - Superresolution Microscopy III: Pointillism, Image Processing, Maastricht, The Netherlands, March 24-27, 2013.

Optical Coherence Correlation Spectroscopy (OCCS)

M. LeuteneggerS. BroilletS. GeissbühlerA. SatoC. Pache  et al.

Focus on Microscopy - Phase: Optical Coherence, Maastricht, The Netherlands, March 24-27, 2013.

2012

Optical Coherence Correlation Spectroscopy (OCCS)

S. BroilletS. GeissbühlerA. SatoC. PacheA. Bouwens  et al.

18th International Workshop on "Single Molecule Spectroscopy and Ultra Sensitive Analysis in the Life Sciences, Berlin, Germany, September 5-7, 2012.

Balanced super-resolution optical fluctuation imaging

S. GeissbuehlerN. L. BocchioC. DellagiacomaC. BerclazM. Leutenegger  et al.

Focus on Microscopy - Super-resolution IV: techniques, Singapore, Singapore, April 1-4, 2012.

Optical coherence microscopy from tissue to cell

T. LasserM. VilligerC. PacheA. BouwensC. Berclaz  et al.

Focus on Microscopy - OCT, ultrafast lasers, Singapore, Singapore, April 1-4, 2012.

Balanced Super-resolution Optical Fluctuation Imaging (bSOFI)

S. GeissbühlerN. BocchioC. DellagiacomaM. GeissbühlerC. Berclaz  et al.

18th International Workshop on "Single Molecule Spectroscopy and Ultra Sensitive Analysis in the Life Sciences", Berlin, Germany, September 5-7, 2012.

2011

Diffractionless Fourier Domain Microscopy

R. A. LeitgebM. GeissbuehlerT. LasserT. SchmollC. Blatter  et al.

Focus on Microscopy - Optical theory and image formation II, Konstanz, Germany, April 17-20, 2011.

Characterization of Nanoparticles Using Non-linear Correlation Spectroscopy

M. GeissbuehlerN. BocchioV. ShcheslavskiyM. LeuteneggerL. Bonacina  et al.

ECBO 2011 - Emerging Technologies: Models and Platforms II, Munich, Germany, May 22-26, 2011.

2010

Super-resolved position and orientation estimation of fluorescent dipoles using 3D steerable filters

S. GeissbühlerF. AguetI. MärkiT. Lasser

BIOS 2010 - Single Molecule Spectroscopy and Imaging III, San Francisco, January 23-28 2010.

2009

Single Molecule Interference: Towards Three-Dimensional Fluorescence Localization Microscopy at the Molecular Level

I. MärkiT. LasserA. Bilenca

CLEO09, Baltimore, USA.

Super-resolved position and orientation from defocused images of fluorescent dipoles

S. GeissbühlerF. AguetI. MärkiT. LasserM. Unser

European Conference on Biomedical Optics, Munich, June 14–18 2009.

Triplet State Imaging

M. GeissbuehlerT. SpielmannA. FormeyI. MärkiB. Hinz  et al.

BiOS 2009 - Three-Dimensional and Multidimensional Microscopy: Image Acquisition and Processing XVI, San Jose, CA, USA, January 24-29,2009.

Three-dimensional Localization of Fluorescent Emitters at the Nano-scale

I. MärkiS. GeissbühlerF. AguetA. BilencaT. Lasser

European Conferences on Biomedical Optics (ECBO), Munich.

Monitoring Oxygen Consumption during Cell Contraction by Triplet State Imaging

M. GeissbuehlerT. SpielmannA. FormeyI. MaerkiB. Hinz  et al.

ECBO 2009, Advanced Microscopy Techniques, Munich, June 14-18 2009.

2008

Towards in vivo small animal imaging

M. L. VilligerJ. GoulleyA. Grapin-BottonM. FriedrichP. Meda  et al.

USGEB 2008 - Biology Meets Engineering, Lausanne, Switzerland, 6-7 Feb 2008.

Triplet imaging contrast by modulated excitation

M. GeissbuehlerT. SpielmannR. VulliamyM. LeuteneggerI. Märki  et al.

Photonics West 2008, BIOS, Three-Dimensional and Multidimensional Microscopy: Image Acquisition and Processing XV, San Jose, CA, USA, January 19-24,2008.

2007

Dual-beam heterodyne FDOCT with high-axial resolution

A. H. BachmannR. MichaelyT. LasserR. A. Leitgeb

BiOS 2007, San Jose, CA, USA, Jan 2007.

Resonant Doppler Fourier domain optical coherence tomography for enhanced retinal blood flow imaging in vivo

R. A. LeitgebA. H. BachmannM. VilligerR. MichaelyC. Blatter  et al.

BiOS 2007, San Jose, CA, USA, Jan 2007.

Single molecule detection at surfaces

M. GeissbuehlerM. LeuteneggerI. MärkiR. RiglerT. Lasser  et al.

Latsis Symposium 2007 on "Optical Trapping for Molecular Interactions", Lausanne, Switzerland, 25-27 Jun 2007.

Single molecule imaging of odorant receptors in tethered lipid membranes

M. LeuteneggerR. RobelekI. MärkiM. GeissbuehlerE. Sinner  et al.

13th International Workshop on "Single Molecule Spectroscopy and Ultrasensitive Analysis in Life Science", Berlin-Adlershof, Germany, 19-21 Sep 2007.

Intensity based quantification of fast retinal blood flow in 3D via high resolution resonant Doppler spectral OCT

R. MichaelyA. H. BachmannM. L. VilligerC. BlatterT. Lasser  et al.

European Conferences on Biomedical Optics: Biophotonics, München, Germany, 17-21 Jun 2007.

Intensity based quantification of fast retinal blood flow in 3D via high resolution resonant Doppler spectral OCT

R. MichaelyA. H. BachmannM. L. VilligerC. BlatterT. Lasser  et al.

BiOS 2007, San Jose, CA, USA, Jan 2007.

2006

Highly confined depth focus for Fourier domain optical coherence microscopy

R. A. LeitgebL. SteinmannC. ImbodenM. VilligerM. Leutenegger  et al.

BiOS 2006, San Jose, CA, USA, Jan 2006.

Dual-color Total Internal Reflection Fluorescence Fluctuation Spectroscopy

M. LeuteneggerH. BlomJ. WidengrenC. EggelingM. Gösch  et al.

8. annual Linz Winter Workshop, Linz, Austria, 3-6 Feb 2006.

Optical Investigation of Skin Morphology and Anatomy

R. MichaelyA. SerovR. A. LeitgebP. JacquotT. Lasser

CTI Medtech Event Award, Bern, Switzerland, 2006-08-30.

Dual-color Total Internal Reflection Fluorescence Fluctuation Spectroscopy

M. LeuteneggerH. BlomJ. WidengrenC. EggelingM. Gösch  et al.

EOS Topical Meeting on Molecular Plasmonic Devices, Engelberg, Switzerland, 27-29 Apr 2006.

High-resolution Fourier domain optical coherence microscopy

R. A. LeitgebL. SteinmannC. ImbodenM. VilligerM. Leutenegger  et al.

BiOS 2006, San Jose, CA, USA, Jan 2006.

Single Molecule Detection at Surfaces

T. LasserM. LeuteneggerV. ShcheslavskiyI. MärkiK. Hassler  et al.

9. Carl Zeiss sponsored workshop on FCS and related methods, Stockholm, Sweden, 4-6 Dec 2006.

Patents

2017

Superresolved synthetic aperture microscope

T. LasserD. SzlagT. LukesA. Descloux

WO2017085618 . 2017.

2016

Gastro-intestinal biomarkers for diagnosis and therapies of proteinopathies

T. LasserT. BolmontT. HarachW. HannaF. Fak  et al.

US2017360853 ; EP3242673 ; WO2016110768 . 2016.

Optical prism for creating multiple views of an image

M. LeuteneggerS. GeissbuehlerT. Lasser

EP3049859 ; EP3049859 ; WO2015044819 . 2016.

2013

Use of waste products for detecting amyloidogenic proteinaceous material in living mammals

T. BolmontP. FraeringT. LasserM. DimtrovT. Harach

WO2013111045 . 2013.

High speed laser Doppler perfusion imaging system e.g. blood flow imaging system, detects laser Doppler signal and/or laser speckle signal from light reflected from selected blood vessel area, to obtain flow data

T. LasserM. AndreM. Friedrich

EP1874181 ; US2013296715 ; US8480579 ; US2009118623 ; EP1874181 ; WO2006111836 ; WO2006111909 . 2013.

2012

Cumulant microscopy

S. GeissbuehlerC. DellagiacomaM. GeissbuehlerT. Lasser

EP2721441 ; US9658442 ; US2014198198 ; EP2721441 ; WO2012172440 ; EP2535755 . 2012.

2011

Apparatus and method for detecting and measuring biomolecular interactions

N. DurandI. MaerkiT. Lasser

ES2914111 ; EP2542900 ; US8938103 ; US2013016887 ; EP2542900 ; WO2011107916 . 2011.

Nanofluidic biosensor and its use for rapid measurement of biomolecular interactions in solution and methods

N. DurandY. FournierT. LasserI. Maerki

EP2504684 ; EP2504684 ; BR112012012787 ; CA2782009 ; US9452927 ; BR112012012787 ; CN102762971 ; JP5685601 ; AU2010322751 ; HK1175527 ; JP2013512428 ; US2013017967 ; CN102762971 ; EP2504684 ; AU2010322751 ; CA2782009 ; WO2011064701 . 2011.

Dark field optical coherence microscopy

M. VilligerC. PacheT. Lasser

EP3425439 ; US9791684 ; US2013010283 ; EP2521934 ; WO2011083420 ; WO2011083420 . 2011.

2010

Functional optical coherent imaging platform for medical application e.g. neurosurgery, has active camera unit that captures image of specific region of test subject after transmitting stimulus signals

M. FriedrichT. LasserM. LeuteneggerI. MärkiE. Martin-Williams  et al.

US10617303 ; EP2309919 ; US2018098702 ; US9757039 ; US2016367145 ; US9066686 ; US2011169978 ; EP2309919 ; WO2010004365 . 2010.

Method for displaying field e.g. tumor, of brain of human patient during surgery of brain, involves acquiring topography data representing topography of field, where output image is displayed based on topography data

T. LasserM. LeuteneggerA. LopezE. Martin-WilliamsW. Nahm  et al.

DE102008051950 ; DE102008051950 ; DE102008051950 ; US2010130869 ; DE102007018641 ; DE102007063626 ; DE102007018641 ; US2009054788 ; JP2008289870 ; DE102007018641 ; EP1982645 . 2010.

2009

Object i.e. aneurysm, examining method for brain of patient, involves evaluating sequence of images by associating pixels with analysis image value depending on temporal changes of image values of pixels in specified frequency range

C. HAUGERT. LASSERM. LEUTENEGGERA. LOPEZE. MARTIN-WILLIAMS  et al.

DE102007048362 ; DE102007048362 ; US8929974 ; US2011090325 ; DE102007048362 ; WO2009046985 ; DE102007048362 ; WO2009046985 . 2009.

Method for recording color images and laser direct imaging signals of object, involves generating colored images, where common complementary metal-oxide semiconductor sensor has multiple sensor elements

C. HaugerT. Lasser

WO2009121633 ; WO2009121633 ; DE102008017390 . 2009.

2008

Method for displaying field of brain of patient during brain surgery involves determining output image from analysis image values and displaying output image

C. HAUGERW. NAHMT. LASSERM. LEUTENEGGERA. LOPEZ  et al.

DE3268718 ; EP0082645 ; GB2112183 ; GB2112183 ; EP0082645 . 2008.

Optical apparatus for dual beam heterodyne Fourier domain optical coherence tomography, has detector that synchronizes phase shift such that sample signal or sample interface moving at arbitrary velocity is detected by phase change

R. LEITGEBA. BACHMANNM. VILLIGERR. MICHAELYT. LASSER

US2010141956 ; EP2122299 ; WO2008087613 ; WO2008087613 . 2008.

2007

Optical imaging apparatus for sample imaging method e.g. in-vivo measurement of full three-dimensional tissue volume has at least one detector that detects resulting spectral interference pattern at exit of interferometer

R. LeitgebT. LasserA. BachmannL. SteinmannM. Villiger

US2009128824 ; WO2007085992 . 2007.

2006

Phase sensitive Fourier domain optical coherence tomography

R. LeitgebA. BachmannT. Lasser

US2009015842 ; EP1872084 ; WO2006100544 . 2006.

Laser perfusion imaging system for acquiring flow-related images of object for medical diagnosis comprises coherent light source and image sensor(s) made by randomly addressed two-dimensional array of integrating photodetectors

A. SerovT. Lasser

EP1874181 ; US2013296715 ; US8480579 ; US2009118623 ; EP1874181 ; WO2006111836 ; WO2006111909 . 2006.

2005

Identification of luminescent molecules comprises fluorescence correlation spectroscopy

R. RiglerT. LasserP.-A. BesseA. RochasA. Serov  et al.

DE20321480 ; US2006226374 ; DE10336080 ; WO2005017598 . 2005.

Solid immersion lens used in a microscope with a lens system is made of a material having a refractive index that is selected so that the numerical aperture of the lens system

R. BrunnerD. MartinR. RaoA. SerovT. Lasser  et al.

WO2005029153 ; DE10343722 ; WO2005029153 . 2005.

2004

Adjustable illumination or detection beam pinhole for laser scanning microscope has two knife blades with triangular apertures moving in front of slit with lamp and optical detector

T. LasserA. LopezT. SidlerR. Gianotti

US8077413 ; US2007285813 ; DE502004003287 ; AT357676 ; EP1625427 ; JP2007500872 ; EP1625427 ; DE10323922 ; WO2004104647 . 2004.

Interferometer coordinate measurement system for use in measurement and machining tools has partially reflecting boundary surfaces within its measurement head with a separation shorter than the coherence length

C. HaugerT. LasserA. SiegelF. HöllerK. Knupfer  et al.

DE10392656 ; DE10260256 ; DE10392656 ; DE10260256 ; WO2004057266 ; WO2004057266 ; DE10260256 ; AU2003290103 ; WO2004057266 . 2004.

2003

Scanning optical near field microscope for use with different contrast methods, including phase contrast microscopy, has an improved photo-detector design that improves resolution and imaging of the smallest structures

M. KempeR. BrunnerT. Lasser

DE10206020 . 2003.

Optically sectioned image generating method for microscopy imaging apparatus involves combining measured characteristics of signals from respective positions of conjugate image plane to generate optically sectioned image of specimen

K. PlamannS. BourquinM. DucrosJ. MiticF. Vuille  et al.

DE60320369 ; JP4256783 ; US7385709 ; DE60320369 ; AT392638 ; EP1466204 ; US2005117172 ; JP2005515493 ; EP1466204 ; AU2003205981 ; WO03060587 ; GB0200819 . 2003.

2002

Method for defining a location in a section under medical examination refers to a system of coordinates and subsequently to a collection of topological data

C. HaugerW. PoeltingerP. ReimerM. Kraume-BonteT. Lasser  et al.

DE10100335 ; JP5250766 ; EP1225454 ; JP4500913 ; JP2010054520 ; EP1225454 ; US6741948 ; US2002120424 ; JP2002243414 ; DE10100335 ; EP1225454 . 2002.

2000

Diode-pumped solid body laser used in ophthalmology comprises an acoustic-optical modulator, a laser crystal, a delay plate and a crystal that doubles the frequency of the laser beam

A. SchumacherM. EdelmannT. Lasser

DE927918 . 2000.

Open-source microscope add-on for structured illumination microscopy

M. T. M. HannebelleE. RaethS. M. LeitaoT. LukesJ. Pospisil  et al.

Nature Communications. 2024. DOI : 10.1038/s41467-024-45567-7.

Soliton microcomb based spectral domain optical coherence tomography

P. J. MarchandJ. RiemensbergerJ. C. SkehanJ.-J. HoM. H. P. Pfeiffer  et al.

Nature Communications. 2021. DOI : 10.1038/s41467-020-20404-9.

Supervised learning to quantify amyloidosis in whole brains of an Alzheimer's disease mouse model acquired with optical projection tomography

D. NguyenV. UhlmannA. L. PlanchetteP. J. MarchandD. Van de Ville  et al.

Biomedical Optics Express. 2019. DOI : 10.1364/BOE.10.003041.

High-Contrast Imaging of Nanodiamonds in Cells by Energy Filtered and Correlative Light-Electron Microscopy: Toward a Quantitative Nanoparticle-Cell Analysis

S. HanM. RaabeL. HodgsonJ. MantellP. Verkade  et al.

Nano Letters. 2019. DOI : 10.1021/acs.nanolett.9b00752.

Optical projection tomography for whole organ imaging

D. Nguyen / T. LasserD. N. A. Van De Ville (Dir.)

Lausanne, EPFL, 2019. DOI : 10.5075/epfl-thesis-9094.

Correcting for photodestruction in super-resolution optical fluctuation imaging

Y. PeetersW. VandenbergS. DuwéA. P. BouwensT. Lukes  et al.

Scientific Reports. 2017. DOI : 10.1038/s41598-017-09666-4.

Coherent Imaging of Cellular Dynamics

M. Sison / T. Lasser (Dir.)

Lausanne, EPFL, 2017. DOI : 10.5075/epfl-thesis-8202.

Reduction of Abeta amyloid pathology in APPPS1 transgenic mice in the absence of gut microbiota

T. HarachN. MarungruangN. DuthilleulV. CheathamK. Mc Coy  et al.

Scientific Reports. 2017. DOI : 10.1038/srep41802.

Label-free three-dimensional imaging of Caenorhabditis elegans with visible optical coherence microscopy

S. CoquozP. J. MarchandA. BouwensL. MouchiroudV. Sorrentino  et al.

Plos One. 2017. DOI : 10.1371/journal.pone.0181676.

3D Time-lapse Imaging and Quantification of Mitochondrial Dynamics

M. SisonS. ChakraborttyJ. ExtermannA. NahasP. J. Marchand  et al.

Scientific Reports. 2017. DOI : 10.1038/srep43275.

Coherent imaging from bacteria to multicellular organisms

S. Coquoz / T. LasserM. Leutenegger (Dir.)

Lausanne, EPFL, 2017. DOI : 10.5075/epfl-thesis-7857.

Massively parallel data processing for quantitative total flow imaging with optical coherence microscopy and tomography

M. SylwestrzakD. SzlagP. J. MarchandA. S. KumarT. Lasser

Computer Physics Communications. 2017. DOI : 10.1016/j.cpc.2017.03.008.

Visible spectrum extended-focus optical coherence microscopy for label-free sub-cellular tomography

P. J. MarchandA. BouwensD. SzlagD. NguyenA. Descloux  et al.

Biomedical Optics Express. 2017. DOI : 10.1364/BOE.8.003343.

Multi-plane super-resolution microscopy

A. Sharipov / T. LasserM. Leutenegger (Dir.)

Lausanne, EPFL, 2017. DOI : 10.5075/epfl-thesis-7570.

Administrations of human adult ischemia-tolerant mesenchymal stem cells and factors reduce amyloid beta pathology in a mouse model of Alzheimer's disease

T. HarachF. JammesC. MullerN. DuthilleulV. Cheatham  et al.

Neurobiology of Aging. 2017. DOI : 10.1016/j.neurobiolaging.2016.11.009.

Quantifying protein densities on cell membranes using super-resolution optical fluctuation imaging

T. LukesD. GlatzovaZ. KvicalovaF. LevetA. Benda  et al.

Nature Communications. 2017. DOI : 10.1038/s41467-017-01857-x.

Superresolved synthetic aperture microscope

T. LasserD. SzlagT. LukesA. Descloux

WO2017085618 . 2017.

Interferometric synthetic aperture microscopy for extended focus optical coherence microscopy

S. CoquozA. BouwensP. J. MarchandJ. ExtermannT. Lasser

Optics Express. 2017. DOI : 10.1364/OE.25.030807.

Super-resolution microscopy live cell imaging and image analysis

T. Lukes / M. KlímaK. FliegelT. Lasser (Dir.)

Czech Technical University in Prague, 2017.

Statistical parametric mapping of stimuli evoked changes in total blood flow velocity in the mouse cortex obtained with extended-focus optical coherence microscopy

P. J. MarchandA. P. BouwensT. BolmontV. K. ShamaeiD. Nguyen  et al.

Biomedical Optics Express. 2017. DOI : 10.1364/BOE.8.000001.

Combining PALM and SOFI for quantitative imaging of focal adhesions in living cells

H. DeschoutT. LukesA. SharipovL. FelettiT. Lasser  et al.

2017. SPIE Photonics West, San Francisco, 27 January-2 February 2017. DOI : 10.1117/12.2252865.

Optical projection tomography for rapid whole mouse brain imaging

D. NguyenP. J. MarchandA. L. PlanchetteJ. NilssonM. Sison  et al.

Biomedical Optics Express. 2017. DOI : 10.1364/BOE.8.005637.

NIR-emitting and photo-thermal active nanogold as mitochondria-specific probes

S. ChakraborttyM. SisonY. WuA. LadenburgerG. Pramanik  et al.

Biomaterials Science. 2017. DOI : 10.1039/c6bm00951d.

Three dimensional time lapse imaging of live cell mitochondria with photothermal optical lock-in optical coherence microscopy (Conference Presentation)

M. SisonS. ChakraborttyJ. ExtermannA. NahasC. Pache  et al.

2016. Conference on Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XX, San Francisco, CA, FEB 15-17, 2016. DOI : 10.1117/12.2214761.

Model-free uncertainty estimation in stochastical optical fluctuation imaging (SOFI) leads to a doubled temporal resolution

V. VandenbergS. DuwéM. LeuteneggerB. MoeyaertB. Krajnik  et al.

Biomedical Optics Express. 2016. DOI : 10.1364/BOE.7.000467.

Gastro-intestinal biomarkers for diagnosis and therapies of proteinopathies

T. LasserT. BolmontT. HarachW. HannaF. Fak  et al.

US2017360853 ; EP3242673 ; WO2016110768 . 2016.

Complementarity of PALM and SOFI for super-resolution live-cell imaging of focal adhesions

H. DeschoutT. LukesA. SharipovD. SzlagL. Feletti  et al.

Nature Communications. 2016. DOI : 10.1038/ncomms13693.

Optical prism for creating multiple views of an image

M. LeuteneggerS. GeissbuehlerT. Lasser

EP3049859 ; EP3049859 ; WO2015044819 . 2016.

High-speed phase-shifting common-path quantitative phase imaging with a piezoelectric actuator

S. CoquozA. NahasM. SisonA. LopezT. Lasser

Journal of Biomedical Optics (JBO). 2016. DOI : 10.1117/1.JBO.21.12.126019.

Extended-focus optical coherence microscopy for high-resolution imaging of the murine brain

S. TamborskiH. C. LyuH. DolezyczekM. MalinowskaG. Wilczynski  et al.

Biomedical Optics Express. 2016. DOI : 10.1364/BOE.7.004400.

Label-free fast 3D coherent imaging reveals pancreatic islet micro-vascularization and dynamic blood flow

C. BerclazD. SzlagD. NguyenJ. ExtermannA. Bouwens  et al.

Biomedical Optics Express. 2016. DOI : 10.1364/Boe.7.004569.

Cross Talk in Full-Field Optical Coherence Tomography

B. KaramataM. LeuteneggerT. Lasser

Handbook of Full-Field Optical Coherence Microscopy: Technology and Applications; Pan Stanford Publishing, 2016. p. 131 - 182.

Imaging of the stroke-related changes in the vascular system of the mouse brain with the use of extended focus Optical Coherence Microscopy

S. TamborskiH. C. LyuD. BukowskaH. DolezyczekG. Wilczynski  et al.

2016. SPIE Photonics West, BiOS, San Francisco, January 13-18, 2016. DOI : 10.1117/12.2214779.

Compressed imaging by sparse random convolution

D. MarcosT. LasserA. LopezA. Bourquard

Optics Express. 2016. DOI : 10.1364/OE.24.001269.

Longitudinal three-dimensional visualisation of autoimmune diabetes by functional optical coherence imaging

C. BerclazA. Schmidt-ChristensenD. SzlagJ. ExtermannL. Hansen  et al.

Diabetologia. 2016. DOI : 10.1007/s00125-015-3819-x.

Fluorescent Nanodiamond–Gold Hybrid Particles for Multimodal Optical and Electron Microscopy Cellular Imaging

W. LiuB. NaydenovS. ChakraborttyB. WuenschK. Hübner  et al.

Nano Letters. 2016. DOI : 10.1021/acs.nanolett.6b02456.

SOFI Simulation Tool: A Software Package for Simulating and Testing Super-Resolution Optical Fluctuation Imaging

A. GirsaultT. LukesA. SharipovS. GeissbuehlerM. Leutenegger  et al.

PloS One. 2016. DOI : 10.1371/journal.pone.0161602.

Structural and Functional Imaging of Pancreatic Islets using Optical Coherence Microscopy

C. Berclaz / T. LasserA. Grapin-Botton (Dir.)

Lausanne, EPFL, 2015. DOI : 10.5075/epfl-thesis-6560.

OCM with Engineered Wavefront

R. A. LeitgebT. LasserM. Villiger

Optical Coherence Tomography; Springer, 2015. p. 913 - 940.

Diffraction-unlimited imaging: from pretty pictures to hard numbers

W. VandenbergM. LeuteneggerT. LasserJ. HofkensP. Dedecker

Cell And Tissue Research. 2015. DOI : 10.1007/s00441-014-2109-0.

Combined Optical Coherence and Fluorescence Microscopy to assess dynamics and specificity of pancreatic beta-cell tracers

C. BerclazC. PacheA. BouwensD. P. SzlagA. Lopez  et al.

Scientific Reports. 2015. DOI : 10.1038/srep10385.

Optical microscopy for biology and life sciences

M. LeuteneggerT. Lasser

Lausanne: Laboratoire d'Optique Biomédicale, EPFL, 2014.

IMAGING White-light diffraction tomography

A. BouwensT. Lasser

Nature Photonics. 2014. DOI : 10.1038/nphoton.2014.44.

Optical Coherence Correlation Spectroscopy

S. Broillet / T. LasserM. Leutenegger (Dir.)

Lausanne, EPFL, 2014. DOI : 10.5075/epfl-thesis-6342.

Optical coherence correlation spectroscopy (OCCS)

S. BroilletA. SatoS. GeissbühlerC. PacheA. Bouwens  et al.

Optics Express. 2014. DOI : 10.1364/OE.22.000782.

Quantitative cerebral blood flow imaging with extended-focus optical coherence microscopy

A. BouwensT. BolmontD. P. SzlagC. BerclazT. Lasser

Optics Letters. 2014. DOI : 10.1364/OL.39.000037.

Live-cell multiplane three-dimensional super-resolution optical fluctuation imaging

S. GeissbuehlerA. SharipovA. GodinatN. L. BocchioP. A. Sandoz  et al.

Nature Communications. 2014. DOI : 10.1038/ncomms6830.

Visible light optical coherence correlation spectroscopy

S. BroilletD. P. SzlagA. BouwensL. MauriziH. Hofmann  et al.

Optics Express. 2014. DOI : 10.1364/OE.22.021944.

Use of waste products for detecting amyloidogenic proteinaceous material in living mammals

T. BolmontP. FraeringT. LasserM. DimtrovT. Harach

WO2013111045 . 2013.

Multiplane 3D superresolution optical fluctuation imaging

S. GeissbuehlerA. SharipovA. GodinatN. BocchioE. Dubikovskaya  et al.

arXiv. 2013.

How to display data by color schemes compatible with red-green color perception deficiencies

M. GeissbuehlerT. Lasser

Optics Express. 2013. DOI : 10.1364/OE.21.009862.

Optical Coherence Correlation Spectroscopy (OCCS)

S. BroilletS. GeissbühlerA. SatoC. PacheA. Bouwens  et al.

BIOS 2013: Single Molecule Spectroscopy and Superresolution Imaging VI, San Francisco, California, USA, February 2-7, 2013.

High speed laser Doppler perfusion imaging system e.g. blood flow imaging system, detects laser Doppler signal and/or laser speckle signal from light reflected from selected blood vessel area, to obtain flow data

T. LasserM. AndreM. Friedrich

EP1874181 ; US2013296715 ; US8480579 ; US2009118623 ; EP1874181 ; WO2006111836 ; WO2006111909 . 2013.

HILBERT TRANSFORM RELATIONS IN FREQUENCY-DOMAIN OPTICAL-COHERENCE TOMOGRAPHIC IMAGING

C. S. SeelamantulaT. Lasser

Journal of the Indian Institute of Science. 2013.

Three-dimensional Super-resolution Optical Fluctuation Imaging

M. LeuteneggerS. GeissbühlerN. L. BocchioC. BerclazT. Lasser

Focus on Microscopy - Superresolution Microscopy III: Pointillism, Image Processing, Maastricht, The Netherlands, March 24-27, 2013.

Optical Coherence Correlation Spectroscopy (OCCS)

M. LeuteneggerS. BroilletS. GeissbühlerA. SatoC. Pache  et al.

Focus on Microscopy - Phase: Optical Coherence, Maastricht, The Netherlands, March 24-27, 2013.

Functional and Structural Imaging with Optical Coherence Microscopy : Principles & Applications

A. Bouwens / T. LasserM. Chergui (Dir.)

Lausanne, EPFL, 2013. DOI : 10.5075/epfl-thesis-5972.

Quantitative lateral and axial flow imaging with optical coherence microscopy and tomography

A. BouwensD. P. SzlagM. SzkulmowskiT. BolmontM. Wojtkowski  et al.

Optics Express. 2013. DOI : 10.1364/OE.21.017711.

Structural and Functional Stochastic Super-Resolution Microscopy

S. Geissbühler / T. LasserM. Leutenegger (Dir.)

Lausanne, EPFL, 2013. DOI : 10.5075/epfl-thesis-5826.

Label-free imaging of cerebral β-amyloidosis with extended-focus optical coherence microscopy

T. BolmontA. BouwensC. PacheM. DimitrovC. Berclaz  et al.

The Journal of neuroscience. 2012. DOI : 10.1523/JNEUROSCI.0925-12.2012.

Real-time Full Field Laser Doppler Imaging

M. LeuteneggerP. HarbiT. ThacherW. RaffoulT. Lasser

2012. 10th International Conference on Vibration Measurements by Laser and Noncontact Techniques - AIVELA', u'10th International Conference on Vibration Measurements by Laser and Noncontact Techniques - AIVELA, Ancona, Italy, June 26-29, 2012. p. 282 - 286. DOI : 10.1063/1.4730568.

Optical Coherence Correlation Spectroscopy (OCCS)

S. BroilletS. GeissbühlerA. SatoC. PacheA. Bouwens  et al.

18th International Workshop on "Single Molecule Spectroscopy and Ultra Sensitive Analysis in the Life Sciences, Berlin, Germany, September 5-7, 2012.

Balanced super-resolution optical fluctuation imaging

S. GeissbuehlerN. L. BocchioC. DellagiacomaC. BerclazM. Leutenegger  et al.

Focus on Microscopy - Super-resolution IV: techniques, Singapore, Singapore, April 1-4, 2012.

Assessment of transferrin recycling by Triplet Lifetime Imaging in living cells

M. GeissbuehlerZ. KadlecovaH.-A. KlokT. Lasser

Biomedical Optics Express. 2012. DOI : 10.1364/BOE.3.002526.

Diabetes imaging — quantitative assessment of islets of Langerhans distribution in murine pancreas using extended-focus optical coherence microscopy

C. BerclazJ. GoulleyM. VilligerA. BouwensE. Martin-williams  et al.

Biomedical Optics Express. 2012. DOI : 10.1364/BOE.3.001365.

Fluorescence correlation spectroscopy with a total internal reflection fluorescence STED microscope (TIRF-STED-FCS)

M. LeuteneggerC. RingemannT. LasserS. W. HellC. Eggeling

Optics Express. 2012. DOI : 10.1364/OE.20.005243.

Contrast Enhancement in Optical Coherence Microscopy

C. Pache / T. Lasser (Dir.)

Lausanne, EPFL, 2012. DOI : 10.5075/epfl-thesis-5566.

Fast three-dimensional imaging of gold nanoparticles in living cells with photothermal optical lock-in Optical Coherence Microscopy

C. PacheN. L. BocchioA. BouwensM. VilligerC. Berclaz  et al.

Optics Express. 2012. DOI : 10.1364/OE.20.021385.

Optical coherence microscopy from tissue to cell

T. LasserM. VilligerC. PacheA. BouwensC. Berclaz  et al.

Focus on Microscopy - OCT, ultrafast lasers, Singapore, Singapore, April 1-4, 2012.

Balanced Super-resolution Optical Fluctuation Imaging (bSOFI)

S. GeissbühlerN. BocchioC. DellagiacomaM. GeissbühlerC. Berclaz  et al.

18th International Workshop on "Single Molecule Spectroscopy and Ultra Sensitive Analysis in the Life Sciences", Berlin, Germany, September 5-7, 2012.

Zero-crossing approach to high-resolution reconstruction in frequency-domain optical-coherence tomography

S. R. KrishnanC. S. SeelamantulaA. BouwensM. LeuteneggerT. Lasser

Journal of the Optical Society of America A: Optics, Image Science and Vision. 2012. DOI : 10.1364/JOSAA.29.002080.

Cumulant microscopy

S. GeissbuehlerC. DellagiacomaM. GeissbuehlerT. Lasser

EP2721441 ; US9658442 ; US2014198198 ; EP2721441 ; WO2012172440 ; EP2535755 . 2012.

Nonlinear Correlation Spectroscopy (NLCS)

M. GeissbuehlerL. BonacinaV. ShcheslavskiyN. BocchioS. Geissbuehler  et al.

Nano Letters. 2012. DOI : 10.1021/nl300070n.

Mapping molecular statistics with balanced super-resolution optical fluctuation imaging (bSOFI)

S. GeissbuehlerN. L. BocchioC. DellagiacomaC. BerclazM. Leutenegger  et al.

Optical Nanoscopy. 2012. DOI : 10.1186/2192-2853-1-4.

Triplet imaging of oxygen consumption during the contraction of a single smooth muscle cell (A7r5)

M. GeissbühlerT. SpielmannA. Formey de Saint LouventI. MärkiM. Leutenegger  et al.

2012. Conference of international society on oxygen transport to tissue, Monte Verità, Ascona, Switzerland, July 18-23, 2010. p. 263 - 268. DOI : 10.1007/978-1-4614-1566-4_39.

Assessing the cellular uptake pathway for poly-Lysine analogues using triplet lifetime imaging

M. GeissbuehlerZ. KadlecovaI. MärkiM. MatasciD. Van De Ville  et al.

Biophysical Society 55th Annual Meeting, Baltimore, Maryland, USA, March 5-9, 2011.

Novel Concepts for Functional High Resolution Microscopy

M. Geissbühler / T. Lasser (Dir.)

Lausanne, EPFL, 2011. DOI : 10.5075/epfl-thesis-5177.

Apparatus and method for detecting and measuring biomolecular interactions

N. DurandI. MaerkiT. Lasser

ES2914111 ; EP2542900 ; US8938103 ; US2013016887 ; EP2542900 ; WO2011107916 . 2011.

Real-time full field laser Doppler imaging

M. LeuteneggerE. Martin-WilliamsP. HarbiT. ThacherW. Raffoul  et al.

Biomedical Optics Express. 2011. DOI : 10.1364/BOE.2.001470.

Nanofluidic biosensor and its use for rapid measurement of biomolecular interactions in solution and methods

N. DurandY. FournierT. LasserI. Maerki

EP2504684 ; EP2504684 ; BR112012012787 ; CA2782009 ; US9452927 ; BR112012012787 ; CN102762971 ; JP5685601 ; AU2010322751 ; HK1175527 ; JP2013512428 ; US2013017967 ; CN102762971 ; EP2504684 ; AU2010322751 ; CA2782009 ; WO2011064701 . 2011.

Nonlinear Correlation Spectroscopy (NLCS) Theory

M. GeissbuehlerS. GeissbuehlerT. Lasser

2011

Comparison between SOFI and STORM

S. GeissbühlerC. DellagiacomaT. Lasser

Biomedical Optics Express. 2011. DOI : 10.1364/BOE.2.000408.

Single Molecule Sensing

C. Dellagiacoma / T. Lasser (Dir.)

Lausanne, EPFL, 2011. DOI : 10.5075/epfl-thesis-5155.

Diffractionless Fourier Domain Microscopy

R. A. LeitgebM. GeissbuehlerT. LasserT. SchmollC. Blatter  et al.

Focus on Microscopy - Optical theory and image formation II, Konstanz, Germany, April 17-20, 2011.

Characterization of Nanoparticles Using Non-linear Correlation Spectroscopy

M. GeissbuehlerN. BocchioV. ShcheslavskiyM. LeuteneggerL. Bonacina  et al.

ECBO 2011 - Emerging Technologies: Models and Platforms II, Munich, Germany, May 22-26, 2011.

Dark field optical coherence microscopy

M. VilligerC. PacheT. Lasser

EP3425439 ; US9791684 ; US2013010283 ; EP2521934 ; WO2011083420 ; WO2011083420 . 2011.

Functional optical coherent imaging platform for medical application e.g. neurosurgery, has active camera unit that captures image of specific region of test subject after transmitting stimulus signals

M. FriedrichT. LasserM. LeuteneggerI. MärkiE. Martin-Williams  et al.

US10617303 ; EP2309919 ; US2018098702 ; US9757039 ; US2016367145 ; US9066686 ; US2011169978 ; EP2309919 ; WO2010004365 . 2010.

Dark-field optical coherence microscopy

C. PacheM. VilligerT. Lasser

2010. BIOS 2010, coherence domain optical methods and optical coherence tomography in biomedicine XIV, San Francisco, USA, January 23-28, 2010. DOI : 10.1117/12.842848.

Towards high resolution optical imaging of beta cells in vivo

M. VilligerJ. GoulleyE. Martin-WilliamsA. Grapin-BottonT. Lasser

Current Pharmaceutical Design. 2010. DOI : 10.2174/138161210791164153.

Super-resolved position and orientation estimation of fluorescent dipoles using 3-D steerable filters

S. GeissbühlerF. AguetI. MärkiT. Lasser

2010. BiOS 2010 - Single Molecule Spectroscopy and Imaging III, San Francisco, January 23-28, 2010. DOI : 10.1117/12.841783.

Targeted Photoswitchable Probe for Nanoscopy of Biological Structures

C. DellagiacomaG. LukinaviciusN. BocchioS. BanalaS. Geissbühler  et al.

Chembiochem. 2010. DOI : 10.1002/cbic.201000189.

Method for displaying field e.g. tumor, of brain of human patient during surgery of brain, involves acquiring topography data representing topography of field, where output image is displayed based on topography data

T. LasserM. LeuteneggerA. LopezE. Martin-WilliamsW. Nahm  et al.

DE102008051950 ; DE102008051950 ; DE102008051950 ; US2010130869 ; DE102007018641 ; DE102007063626 ; DE102007018641 ; US2009054788 ; JP2008289870 ; DE102007018641 ; EP1982645 . 2010.

Measurement of the coherent transfer function

M. VilligerC. PacheT. Lasser

Coherence Domain Optical Methods and Optical Coherence Tomography in Biomedicine XIV, San Francisco, CA, USA, January 23-28, 2010.

Transient State Monitoring by Total Internal Reflection Fluorescence Microscopy

T. SpielmannH. BlomM. GeissbuehlerT. LasserJ. Widengren

The Journal of Physical Chemistry B. 2010. DOI : 10.1021/jp911034v.

Dark-field optical coherence microscopy

M. VilligerC. PacheT. Lasser

Optics Letters. 2010. DOI : 10.1364/OL.35.003489.

Live in vivo imaging of Langerhans islets in normal and diabetic mice by extended focus optical coherence microscopy

J. GoulleyM. VilligerC. BerclazP. MedaA. Grapin-Botton  et al.

2010. 46th Annual Meeting of the European-Association-for-the- Study-of-Diabetes (EASD), Stockholm, SWEDEN, Sep 20-24, 2010. p. S194 - S194.

Three-dimensional nano-localization of single fluorescent emitters

I. MärkiN. BocchioS. GeissbühlerF. AguetA. Bilenca  et al.

Optics Express. 2010. DOI : 10.1364/OE.18.020263.

Super-resolved position and orientation estimation of fluorescent dipoles using 3D steerable filters

S. GeissbühlerF. AguetI. MärkiT. Lasser

BIOS 2010 - Single Molecule Spectroscopy and Imaging III, San Francisco, January 23-28 2010.

Coherent transfer functions and extended depth of field

M. VilligerC. PacheR. A. LeitgebT. Lasser

2010. Coherence Domain Optical Methods and Optical Coherence Tomography in Biomedicine XIV, San Francisco, CA, USA, January 23-28, 2010. DOI : 10.1117/12.840819.

Image formation and tomogram reconstruction in optical coherence microscopy

M. VilligerT. Lasser

Journal of the Optical Society of America A: Optics, Image Science and Vision. 2010. DOI : 10.1364/JOSAA.27.002216.

Biomolecular Diffusion in Nanofluidics

N. Durand / P. RenaudT. Lasser (Dir.)

Lausanne, EPFL, 2010. DOI : 10.5075/epfl-thesis-4736.

Triplet imaging of oxygen consumption during the contraction of a single smooth muscle cell (A7r5)

M. GeissbuehlerT. SpielmannA. FormeyI. MärkiM. Leutenegger  et al.

Biophysical Journal. 2010. DOI : 10.1016/j.bpj.2009.10.006.

Extended Focus Optical Coherence Microscopy : Theory and Application

M. Villiger / T. LasserR. Leitgeb (Dir.)

Lausanne, EPFL, 2010. DOI : 10.5075/epfl-thesis-4787.

In Vivo extended focus Optical Coherence Microscopy of endocrine islets of Langerhans in mice

M. VilligerJ. GoulleyM. FriedrichA. Grapin-BottonP. Meda  et al.

Biomedical Photonics Network day 2009 (BMPN), Fisba Optik AG, St. Gallen, Switzerland, June 10 2009.

Single Molecule Interference: Towards Three-Dimensional Fluorescence Localization Microscopy at the Molecular Level

I. MärkiT. LasserA. Bilenca

CLEO09, Baltimore, USA.

Engineering of Extended Focii for Optical Coherence Microscopy

C. PacheM. VilligerS. RutishauserR. A. LeitgebT. Lasser

ECBO 2009, Optical Coherence Tomography and Coherence Techniques Posters, Munich, Germany, June 14-18 2009.

Steerable filters for orientation estimation and localization of fluorescent dipoles

F. AguetS. GeissbühlerI. MärkiT. LasserM. Unser

2009. IEEE International Symposium on Biomedical Imaging: From Nano to Macro, Boston, Massachusetts, June 28 - July 1, 2009. p. 1166 - 1169. DOI : 10.1109/ISBI.2009.5193265.

Three-Dimensional Localization of Nano-Emitters with Nanometer-Level Precision

I. MärkiS. GeissbühlerT. LasserF. Aguet

2009. Novel Techniques in Microscopy (NTM), Vancouver, CA, April 30, 2009.

High-resolution imaging with simultaneous estimation of position and orientation of single molecules

S. GeissbühlerF. AguetI. MärkiT. LasserM. Unser

Biomedical Photonics Network day 2009 (BMPN), Fisba Optik AG, St. Gallen, Switzerland, June 10 2009.

Triplet imaging by modulated excitation

M. GeissbuehlerT. SpielmannI. MärkiA. FormeyB. Hinz  et al.

Biomedical Photonics Network day 2009 (BMPN), Fisba Optik AG, St. Gallen, Switzerland, June 10 2009.

Object i.e. aneurysm, examining method for brain of patient, involves evaluating sequence of images by associating pixels with analysis image value depending on temporal changes of image values of pixels in specified frequency range

C. HAUGERT. LASSERM. LEUTENEGGERA. LOPEZE. MARTIN-WILLIAMS  et al.

DE102007048362 ; DE102007048362 ; US8929974 ; US2011090325 ; DE102007048362 ; WO2009046985 ; DE102007048362 ; WO2009046985 . 2009.

Diffusion of Single Molecules in Nanochannels

C. DellagiacomaN. F. Y. DurandR. GoetschmannI. MaerkiA. Bertsch  et al.

Biomedical Photonics Network day 2009 (BMPN), Fisba Optik AG, St. Gallen, Switzerland, June 10 2009.

In vivo imaging of pancreatic endocrine islets

M. VilligerJ. GoulleyC. PacheM. FriedrichA. Grapin-Botton  et al.

2009. ECBO 2009, Optical Coherence Tomography and Coherence Techniques IV, Munich, Germany, June 14-18 2009. DOI : 10.1117/12.831864.

Super-resolved position and orientation from defocused images of fluorescent dipoles

S. GeissbühlerF. AguetI. MärkiT. LasserM. Unser

European Conference on Biomedical Optics, Munich, June 14–18 2009.

Imaging of G protein-coupled receptors in solid-supported planar lipid membranes

M. LeuteneggerT. LasserE.-K. SinnerR. Robelek

Biointerphases. 2009. DOI : 10.1116/1.3054189.

Three-dimensional Nano-Localization of Fluroescent Emitters

I. MärkiN. BocchioS. GeissgühlerF. AguetT. Lasser

International Workshop on "Single Molecule Spectroscopy and Ultra Sensitive Analysis in the Life Sciences", Berlin, Germany, September 15-18, 2009.

In vivo imaging of murine endocrine islets of Langerhans with extended-focus optical coherence microscopy

J. GoulleyM. VilligerM. FriedrichA. Grapin-BottonP. Meda  et al.

Diabetologia. 2009. DOI : 10.1007/s00125-009-1383-y.

Triplet State Imaging

M. GeissbuehlerT. SpielmannA. FormeyI. MärkiB. Hinz  et al.

BiOS 2009 - Three-Dimensional and Multidimensional Microscopy: Image Acquisition and Processing XVI, San Jose, CA, USA, January 24-29,2009.

High volume confinement in two-photon total-internal- reflection fluorescence correlation spectroscopy

D. IvanovV. ShcheslavskiyI. MärkiM. LeuteneggerT. Lasser

Applied Physics Letters. 2009. DOI : 10.1063/1.3077309.

Three-dimensional Localization of Fluorescent Emitters at the Nano-scale

I. MärkiS. GeissbühlerF. AguetA. BilencaT. Lasser

European Conferences on Biomedical Optics (ECBO), Munich.

Monitoring Oxygen Consumption during Cell Contraction by Triplet State Imaging

M. GeissbuehlerT. SpielmannA. FormeyI. MaerkiB. Hinz  et al.

ECBO 2009, Advanced Microscopy Techniques, Munich, June 14-18 2009.

Three-Dimensional Localization of Nano-Emitters with Nanometer-Level Precision

I. MärkiS. GeissbühlerF. AguetT. Lasser

2009. OSA Optics & Photonics Congress, Advances in Imaging, Vancouver, CA, April 26-30, 2009. DOI : 10.1364/NTM.2009.NMB3.

Diffusion of Single Molecules in Nanochannels

C. DellagiacomaN. F. Y. DurandR. GoetschmannI. MaerkiA. Bertsch  et al.

ECBO 2009, Advanced Microscopy Techniques Posters, Munich, Germany, June 14-18 2009.

Direct Observation of Transitions between Surface-Dominated and Bulk Diffusion Regimes in Nanochannels

N. F. Y. DurandC. DellagiacomaR. GoetschmannA. BertschI. Maerki  et al.

Analytical Chemistry. 2009. DOI : 10.1021/ac900617b.

Super-resolved position and orientation of fluorescent dipoles

F. AguetS. GeissbühlerI. MärkiT. LasserM. Unser

2009. ECBO 2009, Advanced Microscopy Techniques, Munich, Germany, June 14-18 2009. DOI : 10.1117/12.831488.

High volume confinement in two-photon fluorescence correlation spectroscopy with radially polarized light

D. IvanovV. ShcheslavskiyI. MärkiM. LeuteneggerT. Lasser

2009. BIOS, San Jose, CA, USA, January 24, 2009. DOI : 10.1117/12.807596.

Method for recording color images and laser direct imaging signals of object, involves generating colored images, where common complementary metal-oxide semiconductor sensor has multiple sensor elements

C. HaugerT. Lasser

WO2009121633 ; WO2009121633 ; DE102008017390 . 2009.

Information Limits of Optical Coherence Imaging Through Scattering Media

A. BilencaT. LasserB. E. BoumaR. A. LeitgebG. J. Tearney

Ieee Photonics Journal. 2009. DOI : 10.1109/JPHOT.2009.2026911.

Laser Doppler imaging for intraoperative human brain mapping

A. RaabeD. Van De VilleM. LeuteneggerA. SzelényiE. Hattingen  et al.

NeuroImage. 2009. DOI : 10.1016/j.neuroimage.2008.10.049.

See the Brain at Work—Intraoperative Laser Doppler Functional Brain Imaging

E. J. Martin-WilliamsA. RaabeD. Van De VilleM. LeuteneggerA. Szelenyi  et al.

2009. ECBO 2009, Optical Coherence Tomography and Coherence Techniques IV, Munich, Germany, June 14-18 2009. DOI : 10.1117/12.831813.

Super-resolution orientation estimation and localization of fluorescent dipoles using 3-D steerable filters

F. AguetS. GeissbühlerI. MärkiT. LasserM. Unser

Optics Express. 2009. DOI : 10.1364/OE.17.006829.

Fourier Domain Optical Coherence Microscopy with Extended Depth of Field

M. VilligerA. H. BachmannM. LeuteneggerL. SteinmannT. Lasser  et al.

BMPN DAY AT EPMT, Lausanne, Switzerland, June 4, 2008.

Triplet Imaging by Modulated Excitation

M. GeissbuehlerT. SpielmannI. MärkiA. FormeyA. Gautier  et al.

14th International Workshop on "Single Molecule Spectroscopy and Ultra Sensitive Analysis in the Life Sciences", Berlin-Adlershof, Germany, September 17-19, 2008.

Fast focus field calculations

M. LeuteneggerM. GeissbuehlerI. MärkiR. A. LeitgebT. Lasser

USGEB 2008 - Biology Meets Engineering, Lausanne, Switzerland, 6-7 Feb 2008.

Optical Investigation of Skin Morphology and Anatomy

R. MichaelyA. SerovR. LeitgebP. JacquotT. Lasser

BMPN DAY AT EPMT, Lausanne, Switzerland, June 4, 2008.

Complex ambiguity-free Fourier domain optical coherence tomography through transverse scanning

R. A. LeitgebR. MichaelyT. LasserS. C. Sekhar

The Virtual Journal of Biomedical Optics. 2008.

Detection efficiency in total internal reflection fluorescence microscopy

M. LeuteneggerT. Lasser

Optics Express. 2008. DOI : 10.1364/OE.16.008519.

Single molecule imaging of odorant receptors in supported planar lipid membranes

I. MärkiM. LeuteneggerM. GeissbuehlerR. RobelekE. K. Sinner  et al.

BMPN DAY AT EPMT, Lausanne, Switzerland, June 4, 2008.

Towards in vivo small animal imaging

M. L. VilligerJ. GoulleyA. Grapin-BottonM. FriedrichP. Meda  et al.

USGEB 2008 - Biology Meets Engineering, Lausanne, Switzerland, 6-7 Feb 2008.

Imaging of G protein-coupled receptors in solid- supported planar membranes at the single molecule level

I. MärkiM. LeuteneggerM. GeissbuehlerR. RobelekE. Sinner  et al.

2008. BiOS 2008, San Jose, CA, USA, 19-24 Jan 2008. DOI : 10.1117/12.763088.

Extended focus optical coherence microscopy and fluorescence lifetime imaging

M. L. VilligerC. BlatterA. H. BachmannT. LasserR. A. Leitgeb

2008. BiOS 2008, San Jose, CA, USA, 19-24 Jan 2008. DOI : 10.1117/12.763163.

Phase manipulation without phase shifter for complex FDOCT signal reconstruction and resonant Doppler imaging

R. A. LeitgebR. MichaelyA. H. BachmannM. L. VilligerC. Blatter  et al.

2008. BiOS 2008, San Jose, CA, USA, 19-24 Jan 2008.

k-Microscopy: resolution beyond the diffraction limit

R. A. LeitgebM. GeissbuehlerT. Lasser

BiOS 2008, San Jose, CA, USA, 19-24 Jan 2008.

Imaging of G protein-coupled receptors in solid-supported planar membranes at the single molecule level

I. MärkiM. LeuteneggerM. GeissbuehlerR. RobelekE. Sinner  et al.

USGEB 2008 - Biology Meets Engineering, Lausanne, Switzerland, 6-7 Feb 2008.

Triplet imaging contrast by modulated excitation

M. GeissbuehlerT. SpielmannR. VulliamyM. LeuteneggerI. Märki  et al.

Photonics West 2008, BIOS, Three-Dimensional and Multidimensional Microscopy: Image Acquisition and Processing XV, San Jose, CA, USA, January 19-24,2008.

Tomographie en cohérence optique dans le domaine de Fourier appliquée aux tissus humains

R. Michaely / T. Lasser (Dir.)

Lausanne, EPFL, 2008. DOI : 10.5075/epfl-thesis-4131.

Intraoperative functional brain imaging - hemodynamic response visualization using Laser Doppler

E. Martin-WilliamsD. Van De VilleA. LopezM. LeuteneggerR. Leitgeb  et al.

6th FENS Forum of European Neuroscience, organised by the Federation of European Neuroscience Societies, Geneva, Switzerland, July 12-16, 2008.

Fast focus field calculations

M. LeuteneggerM. GeissbuehlerI. MärkiR. A. LeitgebT. Lasser

2008. BiOS 2008, San Jose, CA, USA, 19-24 Jan 2008. DOI : 10.1117/12.763188.

Optical Investigation of Skin Morphology and Anatomy

R. MichaelyA. SerovR. A. LeitgebP. JacquotT. Lasser

Annual meeting of the Biomedical Photonics Network, Lausanne, Switzerland, June 4, 2008.

Method for displaying field of brain of patient during brain surgery involves determining output image from analysis image values and displaying output image

C. HAUGERW. NAHMT. LASSERM. LEUTENEGGERA. LOPEZ  et al.

DE3268718 ; EP0082645 ; GB2112183 ; GB2112183 ; EP0082645 . 2008.

Enhancement of extended depth of field by digital focusing

M. L. VilligerC. BlatterT. LasserR. A. Leitgeb

BiOS 2008, San Jose, CA, USA, 19-24 Jan 2008.

Frequency encoded assessment of retinal physiology

R. A. LeitgebR. MichaelyA. BachmannT. LasserC. Blatter

2008. 18th Conference on Ophthalmic Technologies, San Jose, CA, Jan 19-21, 2008. DOI : 10.1117/12.764330.

Optical apparatus for dual beam heterodyne Fourier domain optical coherence tomography, has detector that synchronizes phase shift such that sample signal or sample interface moving at arbitrary velocity is detected by phase change

R. LEITGEBA. BACHMANNM. VILLIGERR. MICHAELYT. LASSER

US2010141956 ; EP2122299 ; WO2008087613 ; WO2008087613 . 2008.

k-Microscopy: resolution beyond the diffraction limit

M. GeissbuehlerT. LasserR. A. Leitgeb

2008. BiOS 2008, San Jose, CA, USA, 19-24 Jan 2008. DOI : 10.1117/12.763191.

Optical imaging apparatus for sample imaging method e.g. in-vivo measurement of full three-dimensional tissue volume has at least one detector that detects resulting spectral interference pattern at exit of interferometer

R. LeitgebT. LasserA. BachmannL. SteinmannM. Villiger

US2009128824 ; WO2007085992 . 2007.

Dual-beam heterodyne FDOCT with high-axial resolution

A. H. BachmannR. MichaelyT. LasserR. A. Leitgeb

BiOS 2007, San Jose, CA, USA, Jan 2007.

Resonant Doppler Fourier domain optical coherence tomography for enhanced retinal blood flow imaging in vivo

R. A. LeitgebA. H. BachmannM. VilligerR. MichaelyC. Blatter  et al.

BiOS 2007, San Jose, CA, USA, Jan 2007.

Single molecule detection at surfaces

M. GeissbuehlerM. LeuteneggerI. MärkiR. RiglerT. Lasser  et al.

Latsis Symposium 2007 on "Optical Trapping for Molecular Interactions", Lausanne, Switzerland, 25-27 Jun 2007.

Fourier Domain Optical Coherence Microscopy with extended depth of field

M. VilligerA. H. BachmannM. LeuteneggerL. SteinmannT. Lasser  et al.

Nanoscale Engineering of the Biointerface, Playa del Aro, Spain, 28 May-1 Jun 2007.

Single molecule imaging of odorant receptors in tethered lipid membranes

M. LeuteneggerR. RobelekI. MärkiM. GeissbuehlerE. Sinner  et al.

13th International Workshop on "Single Molecule Spectroscopy and Ultrasensitive Analysis in Life Science", Berlin-Adlershof, Germany, 19-21 Sep 2007.

In vitro Synthesis of GPCRs in a Solid Supported Planar Lipid Membrane System

R. RobelekM. LeuteneggerB. WiltschiE. S. LemkerD. Oesterhelt  et al.

51th Annual Meeting of the Biophysical Society, Baltimore, Maryland, 3-7 Mar 2007.

Intensity based quantification of fast retinal blood flow in 3D via high resolution resonant Doppler spectral OCT

R. MichaelyA. H. BachmannM. L. VilligerC. BlatterT. Lasser  et al.

European Conferences on Biomedical Optics: Biophotonics, München, Germany, 17-21 Jun 2007.

Two color fluorescence correlation spectroscopy (FCS) and total internal reflection FCS

M. GeissbuehlerM. LeuteneggerI. MärkiH. BlomC. Eggeling  et al.

Nanoscale Engineering of the Biointerface, Playa del Aro, Spain, 28 May-1 Jun 2007.

Image formation in fluorescence coherence-gated imaging through scattering media

A. BilencaT. LasserA. OzcanR. A. LeitgebB. E. Bouma  et al.

Optics Express. 2007. DOI : 10.1364/OE.15.002810.

Resonant Doppler flow imaging and optical vivisection of retinal blood vessels

A. H. BachmannM. L. VilligerC. BlatterT. LasserR. A. Leitgeb

Optics Express. 2007. DOI : 10.1364/OE.15.000408.

Intensity based quantification of fast retinal blood flow in 3D via high resolution resonant Doppler spectral OCT

R. MichaelyA. H. BachmannM. L. VilligerC. BlatterT. Lasser  et al.

BiOS 2007, San Jose, CA, USA, Jan 2007.

Single molecule imaging of odorant receptors in supported planar lipid membranes

M. LeuteneggerR. RobelekE. SinnerT. Lasser

CHUV Research day 2007, Lausanne, Switzerland, 2007-02-01.

Phase-locked Fourier domain optical coherence tomography

A. H. Bachmann / T. LasserR. Leitgeb (Dir.)

Lausanne, EPFL, 2007. DOI : 10.5075/epfl-thesis-3847.

Vectorial retinal blood flow and optical vessel vivisection for 3D angiography with high resolution resonant Doppler OCT

R. A. LeitgebR. MichaelyA. H. BachmannM. VilligerC. Blatter  et al.

Investigative Ophthalmology & Visual Science. 2007.

Single molecule imaging of odorant receptors in supported planar lipid membranes

M. LeuteneggerM. GeissbuehlerI. MärkiR. RobelekE. Sinner  et al.

Nanoscale Engineering of the Biointerface, Playa del Aro, Spain, 28 May-1 Jun 2007.

Measurement of retinal physiology using functional Fourier domain OCT concepts

R. A. LeitgebA. H. BachmannM. L. VilligerR. MichaelyC. Blatter  et al.

2007. BiOS 2007, San Jose, CA, USA, Jan 2007. DOI : 10.1117/12.702232.

In vitro Synthesis of GPCRs in a Solid Supported Planar Lipid Membrane System

R. RobelekM. LeuteneggerB. WiltschiE. S. LemkerD. Oesterhelt  et al.

Biophysical Society - 51st Annual Meeting, Baltimore, Maryland, March 3-7, 2007.

Field confinement with aberration correction for solid immersion lens based fluorescence correlation spectroscopy

R. RaoJ. MiticA. SerovR. A. LeitgebT. Lasser

Optics Communications. 2007. DOI : 10.1016/j.optcom.2006.10.044.

Dynamic disorder in horseradish peroxidase observed with total internal reflection fluorescence correlation spectroscopy

K. HasslerP. RiglerH. BlomR. RiglerJ. Widengren  et al.

Optics Express. 2007. DOI : 10.1364/OE.15.005366.

Skin Morphology and Anatomy

R. MichaelyR. A. LeitgebT. Lasser

CHUV Research day 2007, Lausanne, Switzerland, 2007-02-01.

Dual-beam heterodyne Fourier domain optical coherence tomography

A. H. BachmannR. MichaelyT. LasserR. A. Leitgeb

Optics Express. 2007. DOI : 10.1364/OE.15.009254.

Single molecule imaging of odorant receptors in supported planar lipid membranes

R. RobelekM. LeuteneggerE. SinnerT. Lasser

Winterschool, Klosters, Switzerland, 2007-01-14.

Single molecule detection at surfaces

M. LeuteneggerK. HasslerP. RiglerA. BilencaT. Lasser

New Approaches in Biomedical Spectroscopy; American Chemical Society, 2007. p. 1 - 18.

Single molecule detection on surfaces

M. Leutenegger / T. Lasser (Dir.)

Lausanne, EPFL, 2007. DOI : 10.5075/epfl-thesis-3854.

In vitro synthesis of GPCRs in a solid supported planar lipid membrane system

R. RobelekM. LeuteneggerB. WiltschiE. S. LemkeD. Oesterhelt  et al.

Biophysical Journal. 2007.

Complex Ambiguity-Free Fourier Domain Optical Coherence Tomography through Transverse Scanning

R. A. LeitgebR. MichaelyT. LasserS. C. Sekhar

Optics Letters. 2007. DOI : 10.1364/OL.32.003453.

Vectorial reconstruction of retinal blood flow in three dimensions measured with high resolution resonant Doppler Fourier domain optical coherence tomography

R. MichaelyA. H. BachmannM. L. VilligerC. BlatterT. Lasser  et al.

Journal of Biomedical Optics (JBO). 2007. DOI : 10.1117/1.2771553.

Intensity based quantification of fast retinal blood flow in 3D via high resolution resonant Doppler spectral OCT

R. MichaelyA. H. BachmannM. L. VilligerC. BlatterT. Lasser  et al.

2007. Conference on Optical Coherence Tomography and Coherence Techniques III, Munich, GERMANY, Jun 00-19, 2007. DOI : 10.1117/12.728473.

Extended focus Fourier domain optical coherence microscopy assists developmental biology

M. L. VilligerM. BeleutC. BriskenT. LasserR. A. Leitgeb

2007. Optical Coherence Tomography and Coherence Techniques III, Munich, Germany, Sunday 17 June 2007. DOI : 10.1117/12.728370.

Highly confined depth focus for Fourier domain optical coherence microscopy

R. A. LeitgebL. SteinmannC. ImbodenM. VilligerM. Leutenegger  et al.

BiOS 2006, San Jose, CA, USA, Jan 2006.

Combined laser Doppler and laser speckle imaging for real- time blood blow measurements

G. L. CotéA. V. PriezzhevA. SerovT. Lasser

2006. BiOS 2006, San Jose, CA, USA, Jan 2006. DOI : 10.1117/12.646012.

Confining the sampling volume for Fluorescence Correlation Spectroscopy using a sub-wavelength sized aperture

M. LeuteneggerM. GöschA. PerentesP. HoffmannO. J. F. Martin  et al.

Optics Express. 2006. DOI : 10.1364/OPEX.14.000956.

Laser Doppler blood-flow imaging combined with topographical imaging of the sample

F. S. AzarD. N. MetaxasR. MichaelyA. SerovP. Jacquot  et al.

2006. BiOS 2006, San Jose, CA, USA, Jan 2006. DOI : 10.1117/12.645200.

Fast focus field calculations

M. LeuteneggerR. RaoR. A. LeitgebT. Lasser

Optics Express. 2006. DOI : 10.1364/OE.14.011277.

Dual-color Total Internal Reflection Fluorescence Fluctuation Spectroscopy

M. LeuteneggerH. BlomJ. WidengrenC. EggelingM. Gösch  et al.

8. annual Linz Winter Workshop, Linz, Austria, 3-6 Feb 2006.

High-speed laser Doppler imaging of blood flow in biological tissue

V. V. TuchinA. SerovT. Lasser

2006. Saratov Fall Meeting 2005, Saratov, Russia, 27-30 Sep 2005. DOI : 10.1117/12.696924.

Phase sensitive Fourier domain optical coherence tomography

R. LeitgebA. BachmannT. Lasser

US2009015842 ; EP1872084 ; WO2006100544 . 2006.

Heterodyne Fourier domain optical coherence tomography for full range probing with high axial resolution

A. H. BachmannR. A. LeitgebT. Lasser

Optics Express. 2006. DOI : 10.1364/OE.14.001487.

Stochastic Approach to Data Analysis in Fluorescence Correlation Spectroscopy

R. RaoR. LangojuM. GöschP. RiglerA. Serov  et al.

The Journal of Physical Chemistry A. 2006. DOI : 10.1021/jp055763t.

Optical Investigation of Skin Morphology and Anatomy

R. MichaelyA. SerovR. A. LeitgebP. JacquotT. Lasser

CTI Medtech Event Award, Bern, Switzerland, 2006-08-30.

An all-fiber Pr/Yb-doped up-conversion laser in different laser operation modes

M. ZellerH. G. LimbergerT. Lasser

Tm-Technisches Messen. 2006. DOI : 10.1524/teme.2006.73.3.166.

Dual-color Total Internal Reflection Fluorescence Fluctuation Spectroscopy

M. LeuteneggerH. BlomJ. WidengrenC. EggelingM. Gösch  et al.

EOS Topical Meeting on Molecular Plasmonic Devices, Engelberg, Switzerland, 27-29 Apr 2006.

Fluorescence correlation spectroscopy : simulations and bio-chemical applications based on solid immersion lens concept

R. Rao / T. Lasser (Dir.)

Lausanne, EPFL, 2006. DOI : 10.5075/epfl-thesis-3697.

Extended focus depth for Fourier domain optical coherence microscopy

R. A. LeitgebM. VilligerA. H. BachmannL. SteinmannT. Lasser

Optics Letters. 2006. DOI : 10.1364/OL.31.002450.

High-resolution Fourier domain optical coherence microscopy

R. A. LeitgebL. SteinmannC. ImbodenM. VilligerM. Leutenegger  et al.

BiOS 2006, San Jose, CA, USA, Jan 2006.

Dual-color total internal reflection fluorescence cross- correlation spectroscopy

M. LeuteneggerH. BlomJ. WidengrenC. EggelingM. Gösch  et al.

Journal of Biomedical Optics (JBO). 2006. DOI : 10.1117/1.2221714.

Full-field high-speed laser Doppler imaging system for blood-flow measurements

G. E. CohnW. S. GrundfestD. A. BenaronT. Vo-DinhA. Serov  et al.

2006. BiOS 2006, San Jose, CA, USA, Jan 2006. DOI : 10.1117/12.645205.

Single Molecule Detection at Surfaces

T. LasserM. LeuteneggerV. ShcheslavskiyI. MärkiK. Hassler  et al.

9. Carl Zeiss sponsored workshop on FCS and related methods, Stockholm, Sweden, 4-6 Dec 2006.

Single molecule detection and fluorescence correlation spectroscopy on surfaces

K. Hassler / T. Lasser (Dir.)

Lausanne, EPFL, 2006. DOI : 10.5075/epfl-thesis-3433.

Simultaneous Multicolor Fluorescence Cross-Correlation Spectroscopy to Detect Higher Order Molecular Interactions Using Single Wavelength Laser Excitation

L. C. HwangM. GöschT. LasserT. Wohland

Biophysical Journal. 2006. DOI : 10.1529/biophysj.105.074120.

Laser perfusion imaging system for acquiring flow-related images of object for medical diagnosis comprises coherent light source and image sensor(s) made by randomly addressed two-dimensional array of integrating photodetectors

A. SerovT. Lasser

EP1874181 ; US2013296715 ; US8480579 ; US2009118623 ; EP1874181 ; WO2006111836 ; WO2006111909 . 2006.

Single molecule imaging of odorant receptors in supported planar lipid membranes

M. LeuteneggerR. RobelekE. SinnerT. Lasser

EPFL Photonics day 2006, Lausanne, Switzerland, 2006-11-24.

Prism-based multicolor fluorescence correlation spectrometer

L. C. HwangM. LeuteneggerM. GöschT. LasserP. Rigler  et al.

Optics Letters. 2006. DOI : 10.1364/OL.31.001310.

Complex unltrahigh resolution Fourier domain optical coherence tomography

V. V. TuchinJ. A. IzattJ. G. FujimotoA. H. BachmannT. Lasser  et al.

2006. BiOS 2006, San Jose, CA, USA, Jan 2006. DOI : 10.1117/12.648862.

Fabrication of arrays of sub-wavelength nano-apertures in an optically thick gold layer on glass slides for optical studies

A. PerentesI. UtkeB. DwirM. LeuteneggerT. Lasser  et al.

Nanotechnology. 2005. DOI : 10.1088/0957-4484/16/5/025.

Identification of luminescent molecules comprises fluorescence correlation spectroscopy

R. RiglerT. LasserP.-A. BesseA. RochasA. Serov  et al.

DE20321480 ; US2006226374 ; DE10336080 ; WO2005017598 . 2005.

Total internal reflection fluorescence correlation spectroscopy (TIR-FCS) with low background and high count-rate per molecule

K. HasslerM. LeuteneggerP. RiglerR. RaoR. Rigler  et al.

Optics Express. 2005. DOI : 10.1364/OPEX.13.007415.

Time-resolved Hadamard fluorescence imaging

K. HasslerT. AnhutT. Lasser

Applied Optics. 2005. DOI : 10.1364/AO.44.007564.

Parallel dual-color fluorescence cross-correlation spectroscopy using diffractive optical elements

M. GöschH. BlomS. AndereggK. KornP. Thyberg  et al.

Journal of Biomedical Optics (JBO). 2005. DOI : 10.1117/1.2080707.

Speckle statistics in optical coherence tomography

B. KaramataK. HasslerM. LaubscherT. Lasser

Journal of the Optical Society of America A: Optics, Image Science and Vision. 2005. DOI : 10.1364/JOSAA.22.000593.

Solid immersion lens used in a microscope with a lens system is made of a material having a refractive index that is selected so that the numerical aperture of the lens system

R. BrunnerD. MartinR. RaoA. SerovT. Lasser  et al.

WO2005029153 ; DE10343722 ; WO2005029153 . 2005.

Full-field laser Doppler perfusion imaging and monitoring with an intelligent CMOS camera

A. SerovB. SteinacherT. Lasser

Optics Express. 2005. DOI : 10.1364/OPEX.13.003681.

Ultrasensitive reporter protein detection in genetically engineered bacteria

M. WellsM. GöschR. RiglerH. HarmsT. Lasser  et al.

Analytical Chemistry. 2005. DOI : 10.1021/ac048127k.

High count rates with total internal reflection fluorescence correlation spectroscopy

K. HasslerT. AnhutR. RiglerM. GöschT. Lasser

Biophysical Journal. 2005. DOI : 10.1529/biophysj.104.053884.

High-speed laser Doppler perfusion imaging using an integrating CMOS image sensor

A. SerovT. Lasser

Optics Express. 2005. DOI : 10.1364/OPEX.13.006416.

Multiple scattering in optical coherence tomography. II. Experimental and theoretical investigation of cross talk in wide-field optical coherence tomography

B. KaramataM. LeuteneggerM. LaubscherS. BourquinT. Lasser  et al.

Journal of the Optical Society of America A: Optics, Image Science and Vision. 2005. DOI : 10.1364/JOSAA.22.001380.

Multiple scattering in optical coherence tomography. I. Investigation and modeling

B. KaramataM. LaubscherM. LeuteneggerS. BourquinT. Lasser  et al.

Journal of the Optical Society of America A: Optics, Image Science and Vision. 2005. DOI : 10.1364/JOSAA.22.001369.

UV-induced index changes in undoped fluoride glass

M. ZellerT. LasserH. G. LimbergerG. Maze

Journal of Lightwave Technology. 2005. DOI : 10.1109/JLT.2004.841781.

Adjustable illumination or detection beam pinhole for laser scanning microscope has two knife blades with triangular apertures moving in front of slit with lamp and optical detector

T. LasserA. LopezT. SidlerR. Gianotti

US8077413 ; US2007285813 ; DE502004003287 ; AT357676 ; EP1625427 ; JP2007500872 ; EP1625427 ; DE10323922 ; WO2004104647 . 2004.

Spectroscopic optical coherence tomography based on wavelength de-multiplexing and smart pixel array detection

M. LaubscherS. BourquinL. FroehlyB. KaramataT. Lasser

Optics Communications. 2004. DOI : 10.1016/j.optcom.2004.03.084.

High light field confinement for Fluorescence Correlation Spectroscopy using a Solid Immersion Lens

A. SerovR. RaoM. GoeschT. AnhutD. Martin  et al.

Biosensors and Bioelectronics. 2004. DOI : 10.1016/j.bios.2004.02.028.

Photosensitivity and bragg grating technology for upconversion all-fiber lasers

M. Zeller / T. Lasser (Dir.)

Lausanne, EPFL, 2004. DOI : 10.5075/epfl-thesis-2921.

Multiple scattering in wide-field optical coherence tomography

B. Karamata / T. Lasser (Dir.)

Lausanne, EPFL, 2004. DOI : 10.5075/epfl-thesis-3001.

Interferometer coordinate measurement system for use in measurement and machining tools has partially reflecting boundary surfaces within its measurement head with a separation shorter than the coherence length

C. HaugerT. LasserA. SiegelF. HöllerK. Knupfer  et al.

DE10392656 ; DE10260256 ; DE10392656 ; DE10260256 ; WO2004057266 ; WO2004057266 ; DE10260256 ; AU2003290103 ; WO2004057266 . 2004.

Spatially incoherent illumination as a mechanism for cross-talk suppression in wide-field optical coherence tomography

B. KaramataP. LambeletM. LaubscherR. P. SalatheT. Lasser

Optics Letters. 2004. DOI : 10.1364/OL.29.000736.

Non equilibrium catalysis of single enzyme molecules

R. RiglerL. EdmanS. WennmalmM. LeuteneggerT. Anhut  et al.

Abstracts of Papers of the American Chemical Society. 2004.

Innovative experimental concepts for optical coherence tomography

M. Laubscher / T. Lasser (Dir.)

Lausanne, EPFL, 2004. DOI : 10.5075/epfl-thesis-2954.

Application of CMOS image sensors in optical sectioning and polarization microscopy

J. Mitic / T. Lasser (Dir.)

Lausanne, EPFL, 2004. DOI : 10.5075/epfl-thesis-3101.

Parallel single molecule detection with a fully integrated single-photon 2X2 CMOS detector array

M. GoschA. SerovT. AnhutT. LasserA. Rochas  et al.

Journal of Biomedical Optics (JBO). 2004. DOI : 10.1117/1.1781668.

Scanning optical near field microscope for use with different contrast methods, including phase contrast microscopy, has an improved photo-detector design that improves resolution and imaging of the smallest structures

M. KempeR. BrunnerT. Lasser

DE10206020 . 2003.

High-speed femtosecond pump probe spectroscopy with a smart pixel detector array

S. BourquinR. P. PrasankumarF. X. KärtnerJ. G. FujimotoT. Lasser  et al.

Optics Letters. 2003. DOI : 10.1364/OL.28.001588.

Tunable Pr3+-Yb3+-doped all-fiber upconversion laser

M. ZellerH. G. LimbergerT. Lasser

Ieee Photonics Technology Letters. 2003. DOI : 10.1109/LPT.2002.806852.

Multiplexed 3D imaging using wavelength encoded spectral interferometry: a proof of principle

L. FroehlyS. N. MartinT. LasserC. DepeursingeF. Lang

Optics Communications. 2003. DOI : 10.1016/S0030-4018(03)01611-0.

Resonator stability subject to dynamic random-tilt aberration

M. O. HonglerT. LasserG. Evequoz

Journal of the Optical Society of America A: Optics, Image Science and Vision. 2003. DOI : 10.1364/JOSAA.20.000151.

Optically sectioned image generating method for microscopy imaging apparatus involves combining measured characteristics of signals from respective positions of conjugate image plane to generate optically sectioned image of specimen

K. PlamannS. BourquinM. DucrosJ. MiticF. Vuille  et al.

DE60320369 ; JP4256783 ; US7385709 ; DE60320369 ; AT392638 ; EP1466204 ; US2005117172 ; JP2005515493 ; EP1466204 ; AU2003205981 ; WO03060587 ; GB0200819 . 2003.

First fully integrated 2-D array of single-photon detectors in standard CMOS technology

A. RochasM. GoschA. SerovP. A. BesseR. S. Popovic  et al.

Ieee Photonics Technology Letters. 2003. DOI : 10.1109/LPT.2003.813387.

Self-referenced method for optical path difference calibration in low-coherence interferometry

M. LaubscherL. FroehlyB. KaramataR. P. SalathéT. Lasser

Optics Letters. 2003. DOI : 10.1364/OL.28.002476.

Multiplexed 3D imaging using wavelength encoded spectral interferometry: a proof of principle (vol 222, pg 127, 2003)

L. FroehlyS. N. MartinT. LasserC. DepeursingeF. Lang

Optics Communications. 2003. DOI : 10.1016/S0030-4018(03)01730-9.

Optical sectioning in wide-field microscopy obtained by dynamic structured light illumination and detection based on a smart pixel detector array

J. MiticT. AnhutM. MeierM. DucrosA. Serov  et al.

Optics Letters. 2003. DOI : 10.1364/OL.28.000698.

Optical coherence tomography - principles and applications

A. F. FercherW. DrexlerC. K. HitzenbergerT. Lasser

Reports on Progress in Physics. 2003. DOI : 10.1088/0034-4885/66/2/204.

Method for defining a location in a section under medical examination refers to a system of coordinates and subsequently to a collection of topological data

C. HaugerW. PoeltingerP. ReimerM. Kraume-BonteT. Lasser  et al.

DE10100335 ; JP5250766 ; EP1225454 ; JP4500913 ; JP2010054520 ; EP1225454 ; US6741948 ; US2002120424 ; JP2002243414 ; DE10100335 ; EP1225454 . 2002.

Parallel optical coherence tomography in scattering samples using a two-dimensional smart-pixel detector array

M. DucrosM. LaubscherB. KaramataS. BourquinT. Lasser  et al.

Optics Communications. 2002. DOI : 10.1016/S0030-4018(02)01073-8.

Dispersion compensation for optical coherence tomography depth-scan signals by a numerical technique

A. F. FercherC. K. HitzenbergerM. StickerR. ZawadzkiB. Karamata  et al.

Optics Communications. 2002. DOI : 10.1016/S0030-4018(02)01137-9.

Video-rate three-dimensional optical coherence tomography

M. LaubscherM. DucrosB. KaramataT. LasserR. Salathe

Optics Express. 2002. DOI : 10.1364/OE.10.000429.

Optical spectral probing for epithelial tissue characterisation

P. Thueler / T. Lasser (Dir.)

Lausanne, EPFL, 2001. DOI : 10.5075/epfl-thesis-2241.

Numerical dispersion compensation for Partial Coherence Interferometry and Optical Coherence Tomography

A. F. FercherC. K. HitzenbergerM. StickerR. ZawadzkiB. Karamata  et al.

Optics Express. 2001. DOI : 10.1364/OE.9.000610.

Optische Augenlängenmessung für klinische Anwendungen

B. Möller / T. Lasser (Dir.)

Lausanne, EPFL, 2001. DOI : 10.5075/epfl-thesis-2270.

Diode-pumped solid body laser used in ophthalmology comprises an acoustic-optical modulator, a laser crystal, a delay plate and a crystal that doubles the frequency of the laser beam

A. SchumacherM. EdelmannT. Lasser

DE927918 . 2000.

Actively mode-locked visible upconversion fiber laser

D. M. CostantiniH. G. LimbergerT. LasserC. A. P. MullerH. Zellmer  et al.

Optics Letters. 2000. DOI : 10.1364/OL.25.001445.

Corneal morphology in vitro after superficial keractomy with Q-switched Er: YSSG and free-tunning ER: YAG lasers

J. KampmeierD. RussS. SchaferT. Lasser

Journal of Refractive Surgery. 2000. DOI : 10.3928/1081-597X-20000501-08.