Thomas Lehnert
Mission
My scientific work is guided by collaborative projects with strong focus on cutting edge applications in the field of microtechnologies (BioMEMS) and innovative material science. I am currently in charge of the scientific and administrative coordination of the European Project "DetectHIV" aiming in developing a new microfluidic HIV detection platform. This task also comprises the co-direction of two associated PhD thesis. Educational tasks include a doctoral school course on microfluidics.
Publications
Infoscience
L. Dong; M. Cornaglia; G. Krishnamani; J. Zhang; L. Mouchiroud et al. : Reversible and long-term immobilization in a hydrogel-microbead matrix for high-resolution imaging of Caenorhabditis elegans and other small organisms; PLOS ONE. 2018. DOI : 10.1371/journal.pone.0193989.
L. Dong; R. Jankele; M. Cornaglia; T. Lehnert; P. Gonczy et al. : Integrated Microfluidic Device for Drug Studies of Early C. Elegans Embryogenesis; ADVANCED SCIENCE. 2018. DOI : 10.1002/advs.201700751.
R. Krenger; T. Lehnert; M. Gijs : Dynamic microfluidic nanocalorimetry system for measuring Caenorhabditis elegans metabolic heat; LAB ON A CHIP. 2018. DOI : 10.1039/c8lc00238j.
L. Dong : Lab-on-a-chip technologies for manipulation and imaging of C. elegans worms and embryos. Lausanne, EPFL, 2018. DOI : 10.5075/epfl-thesis-8438.
M. Cornaglia; T. Lehnert; M. A. M. Gijs : Microfluidic systems for high-throughput and high-content screening using the nematode Caenorhabditis elegans; Lab On A Chip. 2017. DOI : 10.1039/c7lc00509a.
L. Dong; R. Jankele; J. Zhang; M. Cornaglia; T. Lehnert et al. : An Integrated Microfluidic Device For C-Elegans Early Embryogenesis Studies And Drug Assays. 2017. 30th IEEE International Conference on Micro Electro Mechanical Systems (MEMS), Las Vegas, NV, JAN 22-26, 2017. p. 1244-1247.
L. Dong; J. Zhang; M. Cornaglia; X. Huang; T. Lehnert et al. : C. Elegans Immobilization Using Deformable Microfluidics For In Vivo Studies Of Early Embryogenesis And Intestinal Microbiota. 2017. 30th IEEE International Conference on Micro Electro Mechanical Systems (MEMS), Las Vegas, NV, JAN 22-26, 2017. p. 616-619.
L. Dong; M. Cornaglia; T. Lehnert; M. Gijs : Size-dependent sorting of C. elegans nematodes through an adjustable microfluidic filter structure.. 2016. The 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, Dublin, Ireland, October 9-13, 2016.
L. Dong; M. Cornaglia; T. Lehnert; M. A. M. Gijs : On-chip microfluidic biocommunication assay for studying male-induced demise in C. elegans hermaphrodites; Lab On A Chip. 2016. DOI : 10.1039/c6lc01005a.
R. Padovani : Thermal microsensors for in vitro and in vivo monitoring of chemical and biological processes. Lausanne, EPFL, 2016. DOI : 10.5075/epfl-thesis-7017.
L. Dong; M. Cornaglia; T. Lehnert; M. A. M. Gijs : Versatile size-dependent sorting of C-elegans nematodes and embryos using a tunable microfluidic filter structure; Lab On A Chip. 2016. DOI : 10.1039/c5lc01328c.
M. Cornaglia; G. Krishnamani; L. Mouchiroud; V. Sorrentino; T. Lehnert et al. : Automated longitudinal monitoring of in vivo protein aggregation in neurodegenerative disease C. elegans models; Molecular Neurodegeneration. 2016. DOI : 10.1186/s13024-016-0083-6.
M. Cornaglia; G. N. Krishnamani; L. Mouchiroud; T. Lehnert; J. Auwerx et al. : A microfluidic device for longitudinal studies of C.elegans neurodegenerative disease models. 2015. 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences, Gyeongju, Korea, October 25-29, 2015. p. 689-691.
M. Cornaglia; L. Mouchiroud; A. P. H. Marette; S. Narasimhan; T. Lehnert et al. : Multi-dimensional imaging and phenotyping of C. elegans embryos via an automated microfluidic device. 2015. 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences, Gyeongju, Korea, October 25-29, 2015. p. 686-688.
R. Padovani; T. Lehnert; R. Trouillon; M. Gijs : Nanocalorimetric platform for accurate thermochemical studies in microliter volumes; RSC Advances. 2015. DOI : 10.1039/C5RA22248F.
R. Padovani; T. Lehnert; M. Gijs : A microcalorimetric platform for studying the heat produced by chemical reactions in microliter volumes. 2015. 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences, Gyeongju, Korea, October 25-29, 2015. p. 1861-1863.
M. Cornaglia : Merging microfluidics and micro-array concepts: from molecular to nematode-based bioassays. Lausanne, EPFL, 2015. DOI : 10.5075/epfl-thesis-6808.
M. Cornaglia; R. Trouillon; H. C. Tekin; T. Lehnert; M. A. M. Gijs : Dose-response curve of a microfluidic magnetic bead-based surface coverage sandwich assay; New Biotechnology. 2015. DOI : 10.1016/j.nbt.2015.03.008.
M. Cornaglia; L. Mouchiroud; A. Marette; S. Narasimhan; T. Lehnert et al. : An automated microfluidic platform for C. elegans embryo arraying, phenotyping, and long-term live imaging; Scientific Reports. 2015. DOI : 10.1038/srep10192.
H. Yang; M. Cornaglia; R. Trouillon; T. Lehnert; M. Gijs : Study of constrained Brownian motion of nanoparticles near an interface using optical tweezers. 2015. SPIE Photonics West 2015, San Francisco, USA, February 7-12, 2015. p. 93790W. DOI : 10.1117/12.2078341.
M. Cornaglia; G. H. Krishnamani; M.-P. Meurville; L. Mouchiroud; T. Lehnert et al. : An automated microfluidic platform for reversible immobilization and imaging of C. elegans. 2014. Microfluidics 2014, Heidelberg, Germany, 23-25 July.
M. Cornaglia; R. Trouillon; H. C. Tekin; T. Lehnert; M. A. M. Gijs : Random-walk model of magnetic bead-based surface coverage immunoassays. 2014. Novel Technologies for In Vitro Diagnostics, Diatech 2014, Leuven, Belgium, October 6-8.
M. Cornaglia; R. Trouillon; H. C. Tekin; T. Lehnert; M. Gijs : A random-walk based model to explain ultrasensitive magnetic bead-based immunoassays. 2014. The 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2014), San Antonio, TX, USA, 26-30 October. p. 227-229.
M. Cornaglia; G. H. Krishnamani; M.-P. Meurville; L. Mouchiroud; T. Lehnert et al. : An automated microfluidic platform for long-term high-resolution imaging of C. elegans. 2014. The 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2014), San Antonio, TX, USA, 26-30 October. p. 709-711.
M. Cornaglia; H. Yang; T. Lehnert; M. Gijs : Electrostatic self-assembly of microsphere lens arrays. 2014. 40th International Conference on Micro and Nano Engineering, Lausanne, Switzerland, September 22-26, 2014.
M. Cornaglia; R. Trouillon; H. C. Tekin; T. Lehnert; M. A. M. Gijs : Magnetic Particle-Scanning for Ultrasensitive Immunodetection On-Chip; Analytical Chemistry. 2014. DOI : 10.1021/ac501568g.
M. Cornaglia; H. C. Tekin; T. Lehnert; M. A. M. Gijs : Fine-tuning of magnetic and microfluidic viscous forces for specific magnetic bead-based immunocomplex formation; Journal of Applied Physics. 2013. DOI : 10.1063/1.4817663.
R. Afshar; Y. Moser; T. Lehnert; M. A. M. Gijs : Magnetic particle dosing and size separation in a microfluidic channel. 2011. 15th Transducers Conference, Denver, CO, Jun, 2009. p. 73-80. DOI : 10.1016/j.snb.2009.08.044.
R. Afshar Ghasemlouy; Y. Moser; T. Lehnert; M. Gijs : Three-Dimensional Magnetic Focusing of Superparamagnetic Beads for On-Chip Agglutination Assays; Analytical Chemistry. 2011. DOI : 10.1021/ac102813x.
Y. Moser; R. Forti; S. Jiguet; T. Lehnert; M. A. M. Gijs : Suspended SU-8 structures for monolithic microfluidic channels; Microfluidics and Nanofluidics. 2011. DOI : 10.1007/s10404-010-0657-5.
R. Afshar Ghasemlouy; Y. Moser; T. Lehnert; M. Gijs : Three-dimensional hydro-magnetic focusing and in-flow separation of superparamagnetic beads. 2010. 14th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2010), Groningen, Netherlands, October 3-7, 2010. p. 1220-1222.
R. Afshar Ghasemlouy; Y. Moser; T. Lehnert; M. Gijs : Magneto-microfluidic three-dimensional focusing of magnetic particles. 2010. 8th International Conference on the Scientific and Clinical Applications of Magnetic Carriers, Rostock, Germany, May 25-29, 2010. p. 161-166. DOI : 10.1063/1.3530007.
Y. Moser : Dynamic Actuation of Magnetic Beads for Immunoassays on-chip. Lausanne, EPFL, 2010. DOI : 10.5075/epfl-thesis-4691.
R. Afshar; T. Lehnert; Y. Moser; M. A. Gijs : Magnetic particle dosing, release and separation in a microfluidic chip with magnetic actuation. 2009. 15th International Conference on Solid-State Sensors, Actuators and Microsystems, Denver, CO, USA, June 21 - 25, 2009.
Y. Moser; T. Lehnert; M. A. Gijs : A quadrupolar magnetic actuation system for superparamagnetic particles. 2009. 15th International Conference on Solid-State Sensors, Actuators and Microsystems, Denver, CO, USA, June 21 - 25, 2009.
Y. Moser; L. Thomas; M. Gijs : On-chip immuno-agglutination assay with analyte capture by dynamic manipulation of superparamagnetic beads; Lab on a Chip. 2009. DOI : 10.1039/b907724c.
Y. Moser; T. Lehnert; M. A. M. Gijs : Quadrupolar magnetic actuation of superparamagnetic particles for enhanced microfluidic perfusion; Applied Physics Letters. 2009. DOI : 10.1063/1.3072592.
Y. Moser; T. Lehnert; E. Dupont; R. Afshar; M. Gijs : Active superparamagnetic bead manipulation for immunoassays on-chip. 2008. 12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS, San Diego, CA, USA, October 12-16, 2008. p. 1372-1374.
Y. Moser; T. Lehnert; R. Afshar; G. Sinicco; M. Gijs : Active superparamagnetic bead manipulation on-chip. 2008. 7th International Conference on Scientific and Clinical Applications of Magnetic Carriers, Vancouver, Canada, May 21-24, 2008.
E. Dahan; V. Bize; T. Lehnert; J.-D. Horisberger; M. Gijs : Rapid fluidic exchange microsystem for recording of fast ion channel kinetics in Xenopus oocytes; Lab on a Chip. 2008. DOI : 10.1039/b806404k.
E. Dahan : Integrated microfluidic system for non-invasive electrophysiological measurements on Xenopus oocytes. Lausanne, EPFL, 2008. DOI : 10.5075/epfl-thesis-4151.
R. Afshar; Y. Moser; T. Lehnert; M. Gijs : Microfluidic chip for the separation of magnetic particles. 2007. NanoTech Montreux 2007, Montreux, Switzerland, November 14-16, 2007.
T. Lehnert; M. Wiesli; S. Weigel; O. Agabi; M. A. Gijs et al. : Guiding of Neurite Outgrowth by Topographical Microstructures and Microsieves. 2007. MicroTAS 2007, Paris, France, 7-11 October 2007. p. 730-732.
E. Dahan; V. Bize; T. Lehnert; J. D. Horisberger; M. Gijs : Integrated microsystem for non-invasive electrophysiological measurements on Xenopus oocytes; Biosensors and Bioelectronics. 2007. DOI : 10.1016/j.bios.2007.02.017.
T. Lehnert; D. M. T. Nguyen; L. Baldi Unser; M. A. M. Gijs : Glass reflow on 3-dimensional micro-apertures for electrophysiological measurements on-chip; Microfluidics and Nanofluidics. 2007. DOI : 10.1007/s10404-006-0111-x.
T. Lehnert; D. Nguyen; Y. Moser; M. Gijs : Cell sealing on glass-coated micro- and nano-apertures. 2006. Eurosensors XX, Göteborg, Sweden, September 17-20 2006.
E. Dahan; M. Benabderrazik; T. Lehnert; V. Bize; J.-D. Horisberger et al. : Microfluidic integration of gel-based reference electrodes for electrophysiological measurements on chip. 2006. MicroTAS 2006, Tokyo, Japan, November 5-9, 2006.
R. Maass; D. Grolimund; S. Van Petegem; M. Willimann; M. Jensen et al. : Defect structure in micropillars using X-ray microdiffraction; Applied Physics Letters. 2006.
V. Bize; E. Dahan; T. Lehnert; M. Gijs; J.-D. Horisberger : Chip-based non-invasive voltage clamp on Xenopus laevis oocytes. 2006. Screening Europe 2006, Prague, Czech Republic, 20-22 February 2006.
E. Dahan; V. Bize; T. Lehnert; J. Horisberger; M. Gijs : On-chip non-invasive voltage clamp on Xenopus oocytes. 2005. microTAS 2005, Boston.
T. Lehnert; M. Gijs : Patch-clamp microsystems. 2004. Book chapter 'Lab-on-Chips for Cellomics: Micro- and Nanotechnologies for Life Science', Springer Verlag, H. Andersson and A. van den Berg, editors.
E. Dahan; T. Lehnert; M. Gijs; V. Bize; J.-D. Horisberger : On-chip non-invasive voltage clamp on Xenopus oocytes. 2004. Abstract book Nanotech 2004, the 8th Annual European Conference on MicroNanoscale Technologies for the Biosciences, Montreux, Switzerland, November 16-18.
M. Gijs; T. Lehnert; A. Rida; A. Sayah; D. Solignac et al. : Microtechnologies for bio-applications. 2003. Abstract Korea-Switzerland Workshop on Materials for Medical Diagnostic and Bio-Applications,, KAIST, Daejeon, Republic of Korea, October 5 - 7.
T. Lehnert; M. Gijs : Nano Patch-Clamp Device. 2003. The International Nano Conference 2003, TopNano 21, 4th Annual Report, St.Gallen, Switzerland.
T. Lehnert; A. Laine; M. Gijs : Surface-modification of SiO2 nozzle for patch-clamp measurements on-chip. 2003. Micro Total Analysis Systems 2003, Squaw Valley, CA, USA, October 5-9.
A. Rida; T. Lehnert; M. Gijs : Microfluidic mixer using magnetic beads. 2003. Micro Total Analysis Systems 2003, Squaw Valley, CA, USA, October 5-9.
T. Lehnert; M. Gijs; R. Netzer; U. Bischoff : Realization of hollow SiO2 micronozzles for electrical measurements on living cells; Appl. Phys. Lett.. 2002. DOI : 10.1063/1.1528292.
T. Lehnert; R. Netzer; U. Bischoff; M. Gijs : Positioning of living cells on SiO2 micronozzles for electrical characterization. 2002. Abstract book Nanotech 2002, the 6th Annual European Conference on MicroNanoscale Technologies for the Biosciences, Montreux, Switzerland, November 26-28.
T. Lehnert; M. Gijs; R. Netzer : Nano Patch-Clamp Device. 2002. TopNano 21, 3rd Annual Report, Bern, Switzerland.
T. Lehnert; R. Netzer; U. Bischoff; M. Gijs : SiO2 nozzle array-based patch-clamp microsystem. 2002. in Micro Total Analysis Systems 2002, Nara, Japan, November 3-7.
T. Lehnert; M. Gijs : Nano Patch-Clamp Device. 2001. Top Nano 21, 2nd annual report.
T. Lehnert; M. Gijs : Nano Patch-Clamp Device. 2000. TOP NANO 21, 1st Annual Report 2000, Bern, Switzerland, October 24.
L. Dong; M. Cornaglia; G. Krishnamani; J. Zhang; L. Mouchiroud et al. : Reversible and long-term immobilization in a hydrogel-microbead matrix for high-resolution imaging of Caenorhabditis elegans and other small organisms; PLOS ONE. 2018. DOI : 10.1371/journal.pone.0193989.
L. Dong; R. Jankele; M. Cornaglia; T. Lehnert; P. Gonczy et al. : Integrated Microfluidic Device for Drug Studies of Early C. Elegans Embryogenesis; ADVANCED SCIENCE. 2018. DOI : 10.1002/advs.201700751.
R. Krenger; T. Lehnert; M. Gijs : Dynamic microfluidic nanocalorimetry system for measuring Caenorhabditis elegans metabolic heat; LAB ON A CHIP. 2018. DOI : 10.1039/c8lc00238j.
L. Dong : Lab-on-a-chip technologies for manipulation and imaging of C. elegans worms and embryos. Lausanne, EPFL, 2018. DOI : 10.5075/epfl-thesis-8438.
M. Cornaglia; T. Lehnert; M. A. M. Gijs : Microfluidic systems for high-throughput and high-content screening using the nematode Caenorhabditis elegans; Lab On A Chip. 2017. DOI : 10.1039/c7lc00509a.
L. Dong; R. Jankele; J. Zhang; M. Cornaglia; T. Lehnert et al. : An Integrated Microfluidic Device For C-Elegans Early Embryogenesis Studies And Drug Assays. 2017. 30th IEEE International Conference on Micro Electro Mechanical Systems (MEMS), Las Vegas, NV, JAN 22-26, 2017. p. 1244-1247.
L. Dong; J. Zhang; M. Cornaglia; X. Huang; T. Lehnert et al. : C. Elegans Immobilization Using Deformable Microfluidics For In Vivo Studies Of Early Embryogenesis And Intestinal Microbiota. 2017. 30th IEEE International Conference on Micro Electro Mechanical Systems (MEMS), Las Vegas, NV, JAN 22-26, 2017. p. 616-619.
L. Dong; M. Cornaglia; T. Lehnert; M. Gijs : Size-dependent sorting of C. elegans nematodes through an adjustable microfluidic filter structure.. 2016. The 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, Dublin, Ireland, October 9-13, 2016.
L. Dong; M. Cornaglia; T. Lehnert; M. A. M. Gijs : On-chip microfluidic biocommunication assay for studying male-induced demise in C. elegans hermaphrodites; Lab On A Chip. 2016. DOI : 10.1039/c6lc01005a.
R. Padovani : Thermal microsensors for in vitro and in vivo monitoring of chemical and biological processes. Lausanne, EPFL, 2016. DOI : 10.5075/epfl-thesis-7017.
L. Dong; M. Cornaglia; T. Lehnert; M. A. M. Gijs : Versatile size-dependent sorting of C-elegans nematodes and embryos using a tunable microfluidic filter structure; Lab On A Chip. 2016. DOI : 10.1039/c5lc01328c.
M. Cornaglia; G. Krishnamani; L. Mouchiroud; V. Sorrentino; T. Lehnert et al. : Automated longitudinal monitoring of in vivo protein aggregation in neurodegenerative disease C. elegans models; Molecular Neurodegeneration. 2016. DOI : 10.1186/s13024-016-0083-6.
M. Cornaglia; G. N. Krishnamani; L. Mouchiroud; T. Lehnert; J. Auwerx et al. : A microfluidic device for longitudinal studies of C.elegans neurodegenerative disease models. 2015. 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences, Gyeongju, Korea, October 25-29, 2015. p. 689-691.
M. Cornaglia; L. Mouchiroud; A. P. H. Marette; S. Narasimhan; T. Lehnert et al. : Multi-dimensional imaging and phenotyping of C. elegans embryos via an automated microfluidic device. 2015. 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences, Gyeongju, Korea, October 25-29, 2015. p. 686-688.
R. Padovani; T. Lehnert; R. Trouillon; M. Gijs : Nanocalorimetric platform for accurate thermochemical studies in microliter volumes; RSC Advances. 2015. DOI : 10.1039/C5RA22248F.
R. Padovani; T. Lehnert; M. Gijs : A microcalorimetric platform for studying the heat produced by chemical reactions in microliter volumes. 2015. 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences, Gyeongju, Korea, October 25-29, 2015. p. 1861-1863.
M. Cornaglia : Merging microfluidics and micro-array concepts: from molecular to nematode-based bioassays. Lausanne, EPFL, 2015. DOI : 10.5075/epfl-thesis-6808.
M. Cornaglia; R. Trouillon; H. C. Tekin; T. Lehnert; M. A. M. Gijs : Dose-response curve of a microfluidic magnetic bead-based surface coverage sandwich assay; New Biotechnology. 2015. DOI : 10.1016/j.nbt.2015.03.008.
M. Cornaglia; L. Mouchiroud; A. Marette; S. Narasimhan; T. Lehnert et al. : An automated microfluidic platform for C. elegans embryo arraying, phenotyping, and long-term live imaging; Scientific Reports. 2015. DOI : 10.1038/srep10192.
H. Yang; M. Cornaglia; R. Trouillon; T. Lehnert; M. Gijs : Study of constrained Brownian motion of nanoparticles near an interface using optical tweezers. 2015. SPIE Photonics West 2015, San Francisco, USA, February 7-12, 2015. p. 93790W. DOI : 10.1117/12.2078341.
M. Cornaglia; G. H. Krishnamani; M.-P. Meurville; L. Mouchiroud; T. Lehnert et al. : An automated microfluidic platform for reversible immobilization and imaging of C. elegans. 2014. Microfluidics 2014, Heidelberg, Germany, 23-25 July.
M. Cornaglia; R. Trouillon; H. C. Tekin; T. Lehnert; M. A. M. Gijs : Random-walk model of magnetic bead-based surface coverage immunoassays. 2014. Novel Technologies for In Vitro Diagnostics, Diatech 2014, Leuven, Belgium, October 6-8.
M. Cornaglia; R. Trouillon; H. C. Tekin; T. Lehnert; M. Gijs : A random-walk based model to explain ultrasensitive magnetic bead-based immunoassays. 2014. The 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2014), San Antonio, TX, USA, 26-30 October. p. 227-229.
M. Cornaglia; G. H. Krishnamani; M.-P. Meurville; L. Mouchiroud; T. Lehnert et al. : An automated microfluidic platform for long-term high-resolution imaging of C. elegans. 2014. The 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2014), San Antonio, TX, USA, 26-30 October. p. 709-711.
M. Cornaglia; H. Yang; T. Lehnert; M. Gijs : Electrostatic self-assembly of microsphere lens arrays. 2014. 40th International Conference on Micro and Nano Engineering, Lausanne, Switzerland, September 22-26, 2014.
M. Cornaglia; R. Trouillon; H. C. Tekin; T. Lehnert; M. A. M. Gijs : Magnetic Particle-Scanning for Ultrasensitive Immunodetection On-Chip; Analytical Chemistry. 2014. DOI : 10.1021/ac501568g.
M. Cornaglia; H. C. Tekin; T. Lehnert; M. A. M. Gijs : Fine-tuning of magnetic and microfluidic viscous forces for specific magnetic bead-based immunocomplex formation; Journal of Applied Physics. 2013. DOI : 10.1063/1.4817663.
R. Afshar; Y. Moser; T. Lehnert; M. A. M. Gijs : Magnetic particle dosing and size separation in a microfluidic channel. 2011. 15th Transducers Conference, Denver, CO, Jun, 2009. p. 73-80. DOI : 10.1016/j.snb.2009.08.044.
R. Afshar Ghasemlouy; Y. Moser; T. Lehnert; M. Gijs : Three-Dimensional Magnetic Focusing of Superparamagnetic Beads for On-Chip Agglutination Assays; Analytical Chemistry. 2011. DOI : 10.1021/ac102813x.
Y. Moser; R. Forti; S. Jiguet; T. Lehnert; M. A. M. Gijs : Suspended SU-8 structures for monolithic microfluidic channels; Microfluidics and Nanofluidics. 2011. DOI : 10.1007/s10404-010-0657-5.
R. Afshar Ghasemlouy; Y. Moser; T. Lehnert; M. Gijs : Three-dimensional hydro-magnetic focusing and in-flow separation of superparamagnetic beads. 2010. 14th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2010), Groningen, Netherlands, October 3-7, 2010. p. 1220-1222.
R. Afshar Ghasemlouy; Y. Moser; T. Lehnert; M. Gijs : Magneto-microfluidic three-dimensional focusing of magnetic particles. 2010. 8th International Conference on the Scientific and Clinical Applications of Magnetic Carriers, Rostock, Germany, May 25-29, 2010. p. 161-166. DOI : 10.1063/1.3530007.
Y. Moser : Dynamic Actuation of Magnetic Beads for Immunoassays on-chip. Lausanne, EPFL, 2010. DOI : 10.5075/epfl-thesis-4691.
R. Afshar; T. Lehnert; Y. Moser; M. A. Gijs : Magnetic particle dosing, release and separation in a microfluidic chip with magnetic actuation. 2009. 15th International Conference on Solid-State Sensors, Actuators and Microsystems, Denver, CO, USA, June 21 - 25, 2009.
Y. Moser; T. Lehnert; M. A. Gijs : A quadrupolar magnetic actuation system for superparamagnetic particles. 2009. 15th International Conference on Solid-State Sensors, Actuators and Microsystems, Denver, CO, USA, June 21 - 25, 2009.
Y. Moser; L. Thomas; M. Gijs : On-chip immuno-agglutination assay with analyte capture by dynamic manipulation of superparamagnetic beads; Lab on a Chip. 2009. DOI : 10.1039/b907724c.
Y. Moser; T. Lehnert; M. A. M. Gijs : Quadrupolar magnetic actuation of superparamagnetic particles for enhanced microfluidic perfusion; Applied Physics Letters. 2009. DOI : 10.1063/1.3072592.
Y. Moser; T. Lehnert; E. Dupont; R. Afshar; M. Gijs : Active superparamagnetic bead manipulation for immunoassays on-chip. 2008. 12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS, San Diego, CA, USA, October 12-16, 2008. p. 1372-1374.
Y. Moser; T. Lehnert; R. Afshar; G. Sinicco; M. Gijs : Active superparamagnetic bead manipulation on-chip. 2008. 7th International Conference on Scientific and Clinical Applications of Magnetic Carriers, Vancouver, Canada, May 21-24, 2008.
E. Dahan; V. Bize; T. Lehnert; J.-D. Horisberger; M. Gijs : Rapid fluidic exchange microsystem for recording of fast ion channel kinetics in Xenopus oocytes; Lab on a Chip. 2008. DOI : 10.1039/b806404k.
E. Dahan : Integrated microfluidic system for non-invasive electrophysiological measurements on Xenopus oocytes. Lausanne, EPFL, 2008. DOI : 10.5075/epfl-thesis-4151.
R. Afshar; Y. Moser; T. Lehnert; M. Gijs : Microfluidic chip for the separation of magnetic particles. 2007. NanoTech Montreux 2007, Montreux, Switzerland, November 14-16, 2007.
T. Lehnert; M. Wiesli; S. Weigel; O. Agabi; M. A. Gijs et al. : Guiding of Neurite Outgrowth by Topographical Microstructures and Microsieves. 2007. MicroTAS 2007, Paris, France, 7-11 October 2007. p. 730-732.
E. Dahan; V. Bize; T. Lehnert; J. D. Horisberger; M. Gijs : Integrated microsystem for non-invasive electrophysiological measurements on Xenopus oocytes; Biosensors and Bioelectronics. 2007. DOI : 10.1016/j.bios.2007.02.017.
T. Lehnert; D. M. T. Nguyen; L. Baldi Unser; M. A. M. Gijs : Glass reflow on 3-dimensional micro-apertures for electrophysiological measurements on-chip; Microfluidics and Nanofluidics. 2007. DOI : 10.1007/s10404-006-0111-x.
T. Lehnert; D. Nguyen; Y. Moser; M. Gijs : Cell sealing on glass-coated micro- and nano-apertures. 2006. Eurosensors XX, Göteborg, Sweden, September 17-20 2006.
E. Dahan; M. Benabderrazik; T. Lehnert; V. Bize; J.-D. Horisberger et al. : Microfluidic integration of gel-based reference electrodes for electrophysiological measurements on chip. 2006. MicroTAS 2006, Tokyo, Japan, November 5-9, 2006.
R. Maass; D. Grolimund; S. Van Petegem; M. Willimann; M. Jensen et al. : Defect structure in micropillars using X-ray microdiffraction; Applied Physics Letters. 2006.
V. Bize; E. Dahan; T. Lehnert; M. Gijs; J.-D. Horisberger : Chip-based non-invasive voltage clamp on Xenopus laevis oocytes. 2006. Screening Europe 2006, Prague, Czech Republic, 20-22 February 2006.
E. Dahan; V. Bize; T. Lehnert; J. Horisberger; M. Gijs : On-chip non-invasive voltage clamp on Xenopus oocytes. 2005. microTAS 2005, Boston.
T. Lehnert; M. Gijs : Patch-clamp microsystems. 2004. Book chapter 'Lab-on-Chips for Cellomics: Micro- and Nanotechnologies for Life Science', Springer Verlag, H. Andersson and A. van den Berg, editors.
E. Dahan; T. Lehnert; M. Gijs; V. Bize; J.-D. Horisberger : On-chip non-invasive voltage clamp on Xenopus oocytes. 2004. Abstract book Nanotech 2004, the 8th Annual European Conference on MicroNanoscale Technologies for the Biosciences, Montreux, Switzerland, November 16-18.
M. Gijs; T. Lehnert; A. Rida; A. Sayah; D. Solignac et al. : Microtechnologies for bio-applications. 2003. Abstract Korea-Switzerland Workshop on Materials for Medical Diagnostic and Bio-Applications,, KAIST, Daejeon, Republic of Korea, October 5 - 7.
T. Lehnert; M. Gijs : Nano Patch-Clamp Device. 2003. The International Nano Conference 2003, TopNano 21, 4th Annual Report, St.Gallen, Switzerland.
T. Lehnert; A. Laine; M. Gijs : Surface-modification of SiO2 nozzle for patch-clamp measurements on-chip. 2003. Micro Total Analysis Systems 2003, Squaw Valley, CA, USA, October 5-9.
A. Rida; T. Lehnert; M. Gijs : Microfluidic mixer using magnetic beads. 2003. Micro Total Analysis Systems 2003, Squaw Valley, CA, USA, October 5-9.
T. Lehnert; M. Gijs; R. Netzer; U. Bischoff : Realization of hollow SiO2 micronozzles for electrical measurements on living cells; Appl. Phys. Lett.. 2002. DOI : 10.1063/1.1528292.
T. Lehnert; R. Netzer; U. Bischoff; M. Gijs : Positioning of living cells on SiO2 micronozzles for electrical characterization. 2002. Abstract book Nanotech 2002, the 6th Annual European Conference on MicroNanoscale Technologies for the Biosciences, Montreux, Switzerland, November 26-28.
T. Lehnert; M. Gijs; R. Netzer : Nano Patch-Clamp Device. 2002. TopNano 21, 3rd Annual Report, Bern, Switzerland.
T. Lehnert; R. Netzer; U. Bischoff; M. Gijs : SiO2 nozzle array-based patch-clamp microsystem. 2002. in Micro Total Analysis Systems 2002, Nara, Japan, November 3-7.
T. Lehnert; M. Gijs : Nano Patch-Clamp Device. 2001. Top Nano 21, 2nd annual report.
T. Lehnert; M. Gijs : Nano Patch-Clamp Device. 2000. TOP NANO 21, 1st Annual Report 2000, Bern, Switzerland, October 24.
Enseignement & Phd
Enseignement
- Microengineering,
Programmes doctoraux
- Doctoral Program in Microsystems and Microelectronics
Cours
Materials and technology of microfabrication
L' étudiant apprendra les procédés et les applications des technologies de microfabrication modernes, tels qu'ils sont pratiqués dans une salle blanche, en particulier des techniques modernes qui vont au-delà des procédés classiques, avec focalisation sur... 
Theoretical Microfluidics
Navier-Stokes equation and basic flow solutions / Hydraulic resistance and compliance
Capillary effects / Diffusion and mixing on the microscale
Electrohydrodynamics and Electroosmosis, Nanofluidics
Dielectrophoresis and Magnetophoresis<...