Christian Iseli
EPFL SV PTECH BICC
AAB 1 19 (Bâtiment AAB)
Station 19
1015 Lausanne
Web site: Site web: https://bix.epfl.ch
EPFL SV PTECH BICC
AAB 1 19 (Bâtiment AAB)
Station 19
1015 Lausanne
Web site: Site web: https://sv.epfl.ch/education
EPFL SV PTECH BICC
AAB 1 19 (Bâtiment AAB)
Station 19
1015 Lausanne
Web site: Site web: https://sv.epfl.ch/Council
Publications
Publications Infoscience
- Variant-specific pathophysiological mechanisms of AFF3 differently influence transcriptome profiles
Genome Medicine. 2024-05-30. DOI : 10.1186/s13073-024-01339-y.- Inhibition of anti-tumor immunity by melanoma cell-derived Activin-A depends on STING
Frontiers In Immunology. 2024-01-18. DOI : 10.3389/fimmu.2023.1335207.- A phase 1 trial of adoptive transfer of vaccine-primed autologous circulating T cells in ovarian cancer
Nature Cancer. 2023-09-21. DOI : 10.1038/s43018-023-00623-x.- Chromosome-level organization of the regulatory genome in the Drosophila nervous system
Cell. 2023-08-31. DOI : 10.1016/j.cell.2023.07.008.- Epigenetic silencing of selected hypothalamic neuropeptides in narcolepsy with cataplexy
Proceedings Of The National Academy Of Sciences Of The United States Of America. 2023-05-01. DOI : 10.1073/pnas.2220911120.- DNA modifications impact natural transformation of Acinetobacter baumannii
Nucleic Acids Research. 2023. DOI : 10.1093/nar/gkad377.- Energy-harnessing problem solving of primordial life: Modeling the emergence of catalytic host-nested parasite life cycles
PLOS ONE. 2023. DOI : 10.1371/journal.pone.0281661.- Revisiting the specificity and ability of phospho-S129 antibodies to capture alpha-synuclein biochemical and pathological diversity
Npj Parkinsons Disease. 2022-10-20. DOI : 10.1038/s41531-022-00388-7.- SPICA: Swiss portal for immune cell analysis
Nucleic Acids Research. 2022-01-07. DOI : 10.1093/nar/gkab1055.- Essential role of Cp190 in physical and regulatory boundary formation
Science Advances. 2022. DOI : 10.1126/sciadv.abl8834.- Unexpected post‐glacial colonisation route explains the white colour of barn owls ( Tyto alba ) from the British Isles
Molecular Ecology. 2022. DOI : 10.1111/mec.16250.- Cell-autonomous inflammation of BRCA1-deficient ovarian cancers drives both tumor-intrinsic immunoreactivity and immune resistance via STING
Cell Reports. 2021. DOI : 10.1016/j.celrep.2021.109412.- CTCF loss has limited effects on global genome architecture in Drosophila despite critical regulatory functions
Nature Communications. 2021. DOI : 10.1038/s41467-021-21366-2.- Blood virosphere in febrile Tanzanian children
Emerging Microbes & Infections. 2021-01-01. DOI : 10.1080/22221751.2021.1925161.- Virosaurus A Reference to Explore and Capture Virus Genetic Diversity
Viruses-Basel. 2020-11-01. DOI : 10.3390/v12111248.- Neighbor predation linked to natural competence fosters the transfer of large genomic regions in Vibrio cholerae
eLife. 2019-09-03. DOI : 10.7554/eLife.48212.- MAR-Mediated transgene integration into permissive chromatin and increased expression by recombination pathway engineering
Biotechnology And Bioengineering. 2017. DOI : 10.1002/bit.26086.- The SIB Swiss Institute of Bioinformatics' resources: focus on curated databases
Nucleic Acids Research. 2016. DOI : 10.1093/nar/gkv1310.- ZFN-Site searches genomes for zinc finger nuclease target sites and off-target sites
BMC Bioinformatics. 2011. DOI : 10.1186/1471-2105-12-152.- Probabilistic base calling of Solexa sequencing data
BMC bioinformatics. 2008. DOI : 10.1186/1471-2105-9-431.- A Circuit for the Temperature Compensation of Capacitive Sensors
1996. p. 381-384. DOI : 10.1109/ISCAS.1996.539909.- Spyder
Lausanne, EPFL, 1996. DOI : 10.5075/epfl-thesis-1476.Enseignement & Phd
Enseignement
Life Sciences Engineering
Cours
Bioinformatic Analysis of RNA-sequencing (Fall)
Due to its success, this course will also take place from 1st to 5th September 2025 in room AAC 0 20.
It introduces the workflows and techniques that are used for the analysis of bulk and single-cell RNA-seq data. It empowers students to understand and analyze their own data.
Methods: omics in biomedical research
Les méthodologies à haut débit, appelées "Omiques", permettent de caractériser la complexité et la dynamique de tout système biologique. Ce cours fournira une description générale des méthodes liées au domaine des "Omiques", suivie de rotations pratiques dans les plateformes participantes.