Christian Iseli
EPFL SV PTECH BICC
AAB 1 19 (Bâtiment AAB)
Station 19
1015 Lausanne
+41 21 693 75 36
Office: AAB 1 19
EPFL › SV › PTECH › BICC
Site web: https://bix.epfl.ch
EPFL SV PTECH BICC
AAB 1 19 (Bâtiment AAB)
Station 19
1015 Lausanne
+41 21 693 75 36
Office: AAB 1 19
EPFL › SV › SV-SSV › SSV-ENS
Site web: https://sv.epfl.ch/education
EPFL SV PTECH BICC
AAB 1 19 (Bâtiment AAB)
Station 19
1015 Lausanne
+41 21 693 75 36
Office: AAB 1 19
EPFL › SV › SV-DEC › CF-SV
Site web: https://sv.epfl.ch/Council
Expertise
Computer engineering
- Melanin and Neurotransmitter Signalling Genes Are Differentially Co-Expressed in Growing Feathers of White and Rufous Barn Owls
PIGMENT CELL & MELANOMA RESEARCH. 2025. DOI : 10.1111/pcmr.70001.- Biomathematical enzyme kinetics model of prebiotic autocatalytic RNA networks: degenerating parasite-specific hyperparasite catalysts confer parasite resistance and herald the birth of molecular immunity
PLOS COMPUTATIONAL BIOLOGY. 2025. DOI : 10.1371/journal.pcbi.1012162.- Repairing a deleterious domestication variant in a floral regulator gene of tomato by base editing
Nature Genetics. 2025. DOI : 10.1038/s41588-024-02026-9.- DNA methylation by CcrM contributes to genome maintenance in the Agrobacterium tumefaciens plant pathogen
NUCLEIC ACIDS RESEARCH. 2024. DOI : 10.1093/nar/gkae757.- tRNA-derived fragments in T lymphocyte-beta cell crosstalk and in type 1 diabetes pathogenesis in NOD mice
DIABETOLOGIA. 2024. DOI : 10.1007/s00125-024-06207-3.- Variant-specific pathophysiological mechanisms of AFF3 differently influence transcriptome profiles
Genome Medicine. 2024. DOI : 10.1186/s13073-024-01339-y.- Inhibition of anti-tumor immunity by melanoma cell-derived Activin-A depends on STING
Frontiers In Immunology. 2024. DOI : 10.3389/fimmu.2023.1335207.- A phase 1 trial of adoptive transfer of vaccine-primed autologous circulating T cells in ovarian cancer
Nature Cancer. 2023. DOI : 10.1038/s43018-023-00623-x.- Chromosome-level organization of the regulatory genome in the Drosophila nervous system
Cell. 2023. DOI : 10.1016/j.cell.2023.07.008.- Epigenetic silencing of selected hypothalamic neuropeptides in narcolepsy with cataplexy
Proceedings Of The National Academy Of Sciences Of The United States Of America (PNAS). 2023. DOI : 10.1073/pnas.2220911120.- Energy-harnessing problem solving of primordial life: Modeling the emergence of catalytic host-nested parasite life cycles
PLOS ONE. 2023. DOI : 10.1371/journal.pone.0281661.- DNA modifications impact natural transformation of Acinetobacter baumannii
Nucleic Acids Research. 2023. DOI : 10.1093/nar/gkad377.- Revisiting the specificity and ability of phospho-S129 antibodies to capture alpha-synuclein biochemical and pathological diversity
Npj Parkinsons Disease. 2022. DOI : 10.1038/s41531-022-00388-7.- SPICA: Swiss portal for immune cell analysis
Nucleic Acids Research. 2022. DOI : 10.1093/nar/gkab1055.- Essential role of Cp190 in physical and regulatory boundary formation
Science Advances. 2022. DOI : 10.1126/sciadv.abl8834.- CTCF loss has limited effects on global genome architecture in Drosophila despite critical regulatory functions
Nature Communications. 2021. DOI : 10.1038/s41467-021-21366-2.- Blood virosphere in febrile Tanzanian children
Emerging Microbes & Infections. 2021. DOI : 10.1080/22221751.2021.1925161.- Cell-autonomous inflammation of BRCA1-deficient ovarian cancers drives both tumor-intrinsic immunoreactivity and immune resistance via STING
Cell Reports. 2021. DOI : 10.1016/j.celrep.2021.109412.Enseignement et PhD
Cours
Bioinformatic Analysis of RNA-sequencing (Fall)
BIO-693(a)
Due to its success, this course will take place from 1st to 5th September 2025 in room AAC 0 20. It introduces the workflows and techniques that are used for the analysis of bulk and single-cell RNA-seq data. It empowers students to understand and analyze their own data.
Methods: omics in biomedical research
BIOENG-519
Les méthodologies à haut débit, appelées "Omiques", permettent de caractériser la complexité et la dynamique de tout système biologique. Ce cours fournira une description générale des méthodes liées au domaine des "Omiques", suivie de rotations pratiques dans les plateformes participantes.