Christian Iseli

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christian.iseli@epfl.ch +41 21 693 75 36 https://bix.epfl.ch

https://orcid.org/0000-0002-2296-2863

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EPFL SV PTECH BICC
AAB 1 19 (Bâtiment AAB)
Station 19
1015 Lausanne

+41 21 693 75 36
Local:   AAB 1 19
Local:   AAB 1 22
Local:   AAB 1 21
EPFL > SV > PTECH > BICC

Web site: Site web: https://bix.epfl.ch

EPFL SV PTECH BICC
AAB 1 19 (Bâtiment AAB)
Station 19
1015 Lausanne

+41 21 693 75 36
Local: AAB 1 19
EPFL > SV > SV-SSV > SSV-ENS

Web site: Site web: https://sv.epfl.ch/education

EPFL SV PTECH BICC
AAB 1 19 (Bâtiment AAB)
Station 19
1015 Lausanne

+41 21 693 75 36
Local: AAB 1 19
EPFL > SV > SV-DEC > CF-SV

Web site: Site web: https://sv.epfl.ch/Council

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Données administratives

Publications

Publications Infoscience

- Variant-specific pathophysiological mechanisms of AFF3 differently influence transcriptome profiles

S. Bassani; J. Chrast; G. Ambrosini; N. Voisin; F. Schuetz et al.

Genome Medicine. 2024-05-30. DOI : 10.1186/s13073-024-01339-y.

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- Inhibition of anti-tumor immunity by melanoma cell-derived Activin-A depends on STING

K. Pinjusic; G. Ambrosini; J. Lourenco; N. Fournier; C. Iseli et al.

Frontiers In Immunology. 2024-01-18. DOI : 10.3389/fimmu.2023.1335207.

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- A phase 1 trial of adoptive transfer of vaccine-primed autologous circulating T cells in ovarian cancer

S. Bobisse; V. Bianchi; J. Tanyi; A. Sarivalasis; E. Missiaglia et al.

Nature Cancer. 2023-09-21. DOI : 10.1038/s43018-023-00623-x.

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- Chromosome-level organization of the regulatory genome in the Drosophila nervous system

G. Mohana; J. Dorier; X. Li; M. Mouginot; R. C. Smith et al.

Cell. 2023-08-31. DOI : 10.1016/j.cell.2023.07.008.

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- Epigenetic silencing of selected hypothalamic neuropeptides in narcolepsy with cataplexy

A. Seifinejad; M. Ramosaj; L. Shan; S. Li; M.-L. Possovre et al.

Proceedings Of The National Academy Of Sciences Of The United States Of America. 2023-05-01. DOI : 10.1073/pnas.2220911120.

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- DNA modifications impact natural transformation of Acinetobacter baumannii

N. Vesel; C. Iseli; N. Guex; A. Lemopoulos; M. Blokesch

Nucleic Acids Research. 2023. DOI : 10.1093/nar/gkad377.

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- Energy-harnessing problem solving of primordial life: Modeling the emergence of catalytic host-nested parasite life cycles

J. Villà-Freixa; B. Conrad; C. Iseli; M. Pirovino

PLOS ONE. 2023. DOI : 10.1371/journal.pone.0281661.

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- Revisiting the specificity and ability of phospho-S129 antibodies to capture alpha-synuclein biochemical and pathological diversity

H. A. Lashuel; A.-L. Mahul-Mellier; S. Novello; R. N. Hegde; Y. Jasiqi et al.

Npj Parkinsons Disease. 2022-10-20. DOI : 10.1038/s41531-022-00388-7.

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- SPICA: Swiss portal for immune cell analysis

M. Andreatta; F. P. A. David; C. Iseli; N. Guex; S. J. Carmona

Nucleic Acids Research. 2022-01-07. DOI : 10.1093/nar/gkab1055.

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- Essential role of Cp190 in physical and regulatory boundary formation

A. Kaushal; J. Dorier; B. Wang; G. Mohana; M. Taschner et al.

Science Advances. 2022. DOI : 10.1126/sciadv.abl8834.

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- Unexpected post‐glacial colonisation route explains the white colour of barn owls ( Tyto alba ) from the British Isles

A. P. Machado; T. Cumer; C. Iseli; E. Beaudoing; A. Ducrest et al.

Molecular Ecology. 2022. DOI : 10.1111/mec.16250.

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- Cell-autonomous inflammation of BRCA1-deficient ovarian cancers drives both tumor-intrinsic immunoreactivity and immune resistance via STING

M. Bruand; D. Barras; M. Mina; E. Ghisoni; M. Morotti et al.

Cell Reports. 2021. DOI : 10.1016/j.celrep.2021.109412.

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- CTCF loss has limited effects on global genome architecture in Drosophila despite critical regulatory functions

A. Kaushal; G. Mohana; J. Dorier; I. Özdemir; A. Omer et al.

Nature Communications. 2021. DOI : 10.1038/s41467-021-21366-2.

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- Blood virosphere in febrile Tanzanian children

S. Cordey; F. Laubscher; M.-A. Hartley; T. Junier; K. Keitel et al.

Emerging Microbes & Infections. 2021-01-01. DOI : 10.1080/22221751.2021.1925161.

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- Virosaurus A Reference to Explore and Capture Virus Genetic Diversity

A. Gleizes; F. Laubscher; N. Guex; C. Iseli; T. Junier et al.

Viruses-Basel. 2020-11-01. DOI : 10.3390/v12111248.

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- Neighbor predation linked to natural competence fosters the transfer of large genomic regions in Vibrio cholerae

N. Matthey; S. Stutzmann; C. Stoudmann; N. Guex; C. Iseli et al.

eLife. 2019-09-03. DOI : 10.7554/eLife.48212.

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- MAR-Mediated transgene integration into permissive chromatin and increased expression by recombination pathway engineering

K. Kostyrko; S. Neuenschwander; T. Junier; A. Regamey; C. Iseli et al.

Biotechnology And Bioengineering. 2017. DOI : 10.1002/bit.26086.

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- The SIB Swiss Institute of Bioinformatics' resources: focus on curated databases

L. A. Bultet; J. Aguilar Rodriguez; C. H. Ahrens; E. L. Ahrne; N. Ai et al.

Nucleic Acids Research. 2016. DOI : 10.1093/nar/gkv1310.

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- ZFN-Site searches genomes for zinc finger nuclease target sites and off-target sites

T. J. Cradick; G. Ambrosini; C. Iseli; P. Bucher; A. P. McCaffrey

BMC Bioinformatics. 2011. DOI : 10.1186/1471-2105-12-152.

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- Probabilistic base calling of Solexa sequencing data

J. Rougemont; A. Amzallag; C. Iseli; L. Farinelli; I. Xenarios et al.

BMC bioinformatics. 2008. DOI : 10.1186/1471-2105-9-431.

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- A Circuit for the Temperature Compensation of Capacitive Sensors

M. Grigorie; C. de Raad Iseli; F. Krummenacher; C. Enz

1996. p. 381-384. DOI : 10.1109/ISCAS.1996.539909.

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- Spyder

C. Iseli

Lausanne, EPFL, 1996. DOI : 10.5075/epfl-thesis-1476.

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Enseignement & Phd

Cours

Bioinformatic Analysis of RNA-sequencing (Fall)

(Fiche de cours pas encore validée par la section)

Bioinformatic Analysis of RNA-sequencing (Spring)

Methods: omics in biomedical research

(Fiche de cours pas encore validée par la section)

Christian Iseli

Publications

Publications Infoscience

- Variant-specific pathophysiological mechanisms of AFF3 differently influence transcriptome profiles

- Inhibition of anti-tumor immunity by melanoma cell-derived Activin-A depends on STING

- A phase 1 trial of adoptive transfer of vaccine-primed autologous circulating T cells in ovarian cancer

- Chromosome-level organization of the regulatory genome in the Drosophila nervous system

- Epigenetic silencing of selected hypothalamic neuropeptides in narcolepsy with cataplexy

- DNA modifications impact natural transformation of Acinetobacter baumannii

- Energy-harnessing problem solving of primordial life: Modeling the emergence of catalytic host-nested parasite life cycles

- Revisiting the specificity and ability of phospho-S129 antibodies to capture alpha-synuclein biochemical and pathological diversity

- SPICA: Swiss portal for immune cell analysis

- Essential role of Cp190 in physical and regulatory boundary formation

- Unexpected post‐glacial colonisation route explains the white colour of barn owls ( Tyto alba ) from the British Isles

- Cell-autonomous inflammation of BRCA1-deficient ovarian cancers drives both tumor-intrinsic immunoreactivity and immune resistance via STING

- CTCF loss has limited effects on global genome architecture in Drosophila despite critical regulatory functions

- Blood virosphere in febrile Tanzanian children

- Virosaurus A Reference to Explore and Capture Virus Genetic Diversity

- Neighbor predation linked to natural competence fosters the transfer of large genomic regions in Vibrio cholerae

- MAR-Mediated transgene integration into permissive chromatin and increased expression by recombination pathway engineering

- The SIB Swiss Institute of Bioinformatics' resources: focus on curated databases

- ZFN-Site searches genomes for zinc finger nuclease target sites and off-target sites

- Probabilistic base calling of Solexa sequencing data

- A Circuit for the Temperature Compensation of Capacitive Sensors

- Spyder

Enseignement & Phd

Cours

Bioinformatic Analysis of RNA-sequencing (Fall)

Bioinformatic Analysis of RNA-sequencing (Spring)

Methods: omics in biomedical research

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