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Pascal Miéville

pascal.mieville@epfl.ch +41 21 693 86 25

EPFL SB ISIC SWISSCAT
CH A2 474 (Bâtiment CH)
Station 6
1015 Lausanne

Expertise

Nuclear Magnetic Resonance
Analytical Chemistry
Labautomation
Digital Chemistry

Mission

Leading the conception and development of the Swiss CAT West Hub project. The aim of the Swiss CAT project is to develop a entirely automated and data-driven infrastructure for homogeneous catalysis discovery and optimization. Teaching structural elucidation, mass spectrometry to Bachelor students and digital and automation chemistry to Master and Doctoral  students.

Publications Pascal Miéville

[16] Dynamic aggregation of the mid-sized gadolinium complex {Ph-4[Gd(DTTA)(H2O)(2)](-)(3)}

H. Jaccard; P. Mieville; C. Cannizzo; C. R. Mayer; L. Helm

Journal of Biological Inorganic Chemistry. 2014. DOI : 10.1007/s00775-013-1036-y.

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[15] Dynamic Nuclear Polarization and Other Magnetic Ideas at EPFL

A. Bornet; J. Milani; S. Wang; D. Mammoli; R. Buratto  et al.

Chimia. 2012. DOI : 10.2533/chimia.2012.734.

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[14] Dynamic nuclear polarization of quadrupolar nuclei using cross polarization from protons: surface-enhanced aluminium-27 NMR

V. Vitzthum; P. Mieville; D. Carnevale; M. A. Caporini; D. Gajan  et al.

Chemical Communications. 2012. DOI : 10.1039/c2cc15905h.

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[13] Surface Functionalisation of Alumina Ceramic Foams with Organic Ligands

H. Comas; V. Laporte; F. Borcard; P. Miéville; F. Krauss Juillerat  et al.

ACS Applied Materials & Interfaces. 2012. DOI : 10.1021/am201638a.

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[12] Fractional Spin-Labeling of Polymers for Enhancing NMR Sensitivity by Solvent-Free Dynamic Nuclear Polarization

V. Vitzthum; F. Borcard; S. Jannin; M. Morin; P. Miéville  et al.

ChemPhysChem. 2011. DOI : 10.1002/cphc.201100630.

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[11] Synthesis, complexation and NMR relaxation properties of Gd3+ complexes of Mes(DO3A)3

P. Miéville; H. Jaccard; F. Reviriego; R. Tripier; L. Helm

Dalton Transactions. 2011. DOI : 10.1039/c0dt01597k.

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[10] NMR of Insensitive Nuclei Enhanced by Dynamic Nuclear Polarization

P. Miéville; S. Jannin; L. Helm; G. Bodenhausen

CHIMIA International Journal for Chemistry. 2011. DOI : 10.2533/chimia.2011.260.

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[9] Extending Timescales and Narrowing Linewidths in NMR

T. F. Segawa; A. Bornet; N. Salvi; P. Miéville; V. Vitzthum  et al.

CHIMIA International Journal for Chemistry. 2011. DOI : 10.2533/chimia.2011.652.

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[8] A spinning thermometer to monitor microwave heating and glass transitions in dynamic nuclear polarization

P. Miéville; V. Vitzthum; M. A. Caporini; S. Jannin; S. Gerber-Lemaire  et al.

Magnetic Resonance in Chemistry. 2011. DOI : 10.1002/mrc.2811.

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[7] Effect of Humic Substance Photoalteration on Lead Bioavailability to Freshwater Microalgae

J. Spierings; I. A. M. Worms; P. Mieville; V. Slaveykova

Environmental Science & Technology. 2011. DOI : 10.1021/es104288y.

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[6] Fast Characterization of Functionalized Silica Materials by Silicon-29 Surface-Enhanced NMR Spectroscopy Using Dynamic Nuclear Polarization

M. Lelli; D. Gajan; A. Lesage; M. A. Caporini; V. Vitzthum  et al.

Journal Of The American Chemical Society. 2011. DOI : 10.1021/ja110791d.

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[5] Relaxometry of insensitive nuclei: Optimizing dissolution dynamic nuclear polarization

P. Miéville; S. Jannin; G. Bodenhausen

Journal of Magnetic Resonance. 2011. DOI : 10.1016/j.jmr.2011.02.006.

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[4] Surface Enhanced NMR Spectroscopy by Dynamic Nuclear Polarization

A. Lesage; M. Lelli; D. B. R. A. Gajan; M. A. Caporini; V. Vitzthum  et al.

Journal of the American Chemical Society. 2010. DOI : 10.1021/ja104771z.

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[3] Scavenging Free Radicals To Preserve Enhancement and Extend Relaxation Times in NMR using Dynamic Nuclear Polarization

P. Miéville; P. Ahuja; R. Sarkar; S. Jannin; P. R. Vasos  et al.

Angewandte Chemie International Edition. 2010. DOI : 10.1002/anie.201000934.

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[2] Hyperpolarizing Gases via Dynamic Nuclear Polarization and Sublimation

A. Comment; S. Jannin; J.-N. Hyacinthe; P. Miéville; R. Sarkar  et al.

Physical Review Letters. 2010. DOI : 10.1103/PhysRevLett.105.018104.

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[1] Kinetics of Yttrium-Ligand Complexation Monitored Using Hyperpolarized 89Y as a Model for Gadolinium in Contrast Agents

P. Miéville; S. Jannin; L. Helm; G. Bodenhausen

Journal of the American Chemical Society. 2010. DOI : 10.1021/ja1013954.

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Teaching & PhD

Current Phd

Leander Choudhury

Courses

Automated analytical and synthetic chemistry 1

ChE-602

The course gives a general understanding of lab automation theory and practical knowledge. It is structured to integrate theoretical foundations, hands-on practical exercises (e.g., Arduino programming), and individualized project analysis.

Automated and data-driven laboratories

CH-400

In this course, taught by experts from the Swiss CAT+ West Hub, students will be introduced to key concepts in automation and data-driven chemistry. Using real-world cases, students will learn the theoretical skills and practical tools needed to automate a laboratory.

Structural analysis

CH-314

The aim of this course is to treat three of the major techniques for structural characterization of molecules used in chemistry and chemical engineering: mass spectrometry, NMR, and X-ray techniques.