Molecular mechanism of plasmid elimination by the DdmDE defense system

L. Loeff; D. W. Adams; C. Chanez; S. Stutzmann; L. Righi  et al.

DOI : 10.1126/science.adq0534

Interactions between pili affect the outcome of bacterial competition driven by the type VI secretion system

S. B. Otto; R. M. Servajean; A. Lemopoulos; A.-F. Bitbol; M. Blokesch

DOI : 10.1016/j.cub.2024.04.041

Capsular Polysaccharide Restrains Type VI Secretion in Acinetobacter baumannii

N. O. Flaugnatti; L. Bader; M.-C. Croisier-Coeytaux; M. Blokesch

DOI : 10.1101/2024.04.23.590769

Vibrio cholerae pathogenicity island 2 encodes two distinct types of restriction systems

G. Vizzarro; A. Lemopoulos; D. W. Adams; M. Blokesch

DOI : 10.1101/2024.04.04.588119

Genome sequences of Vibrio cholerae strains isolated in the DRC between 2009 and 2012

A. Lemopoulos; B. Miwanda; N. C. Drebes Dorr; S. Stutzmann; D. Bompangue  et al.

DOI : 10.1128/mra.00827-23

Q & A - Melanie Blokesch

M. Blokesch

DOI : 10.1016/j.cub.2024.04.015

Dangerous acquaintances: the interplay between type IV pili and the type VI secretion system during Vibrio cholerae's environmental lifestyle

S. B. Otto

Interactions between pili affect the outcome of bacterial competition driven by the type VI secretion system

S. B. Otto; R. M. Servajean; A. Lemopoulos; A.-F. Bitbol; M. Blokesch

DOI : 10.1101/2023.10.25.564063

DNA modifications impact natural transformation of Acinetobacter baumannii

N. Vesel; C. Iseli; N. Guex; A. Lemopoulos; M. Blokesch

DOI : 10.1093/nar/gkad377

Sporadic type VI secretion in seventh pandemic Vibrio cholerae

A. Proutière; N. C. Drebes Dorr; L. Bader; S. Stutzmann; L. C. Metzger  et al.

DOI : 10.1099/mic.0.001329

Recombinant bacteria resistant to horizontal gene transfer and phage infection

M. Blokesch; M. J. Jaskolska; D. W. Adams

Single nucleotide polymorphism determines constitutive versus inducible type VI secretion in Vibrio cholerae

N. C. Drebes Dörr; A. Proutière; M. Jaskólska; S. Stutzmann; L. Bader  et al.

DOI : 10.1038/s41396-022-01234-7

Solving the mystery of the missing plasmids in seventh pandemic Vibrio cholerae strains

M. Blokesch

DOI : 10.1038/d41586-022-00778-0

Two defence systems eliminate plasmids from seventh pandemic Vibrio cholerae

M. Jaskólska; D. W. Adams; M. Blokesch

DOI : 10.1038/s41586-022-04546-y

The VarA-CsrA regulatory pathway influences cell shape in Vibrio cholerae

L. F. Lemos Rocha; K. Peters; J. Biboy; J. S. Depelteau; A. Briegel  et al.

DOI : 10.1371/journal.pgen.1010143

How Vibrio cholerae adapts to the environment: from cell shape transitions to antagonistic behavior

L. F. Lemos Rocha

Natural competence of the pathogen Acinetobacter baumannii: an elusive phenomenon

N. Vesel

Human commensal gut Proteobacteria withstand type VI secretion attacks through immunity protein-independent mechanisms

N. Flaugnatti; S. Isaac; L. F. Lemos Rocha; S. Stutzmann; O. Rendueles  et al.

DOI : 10.1038/s41467-021-26041-0

Pilus production in Acinetobacter baumannii is growth phase dependent and essential for natural transformation

N. Vesel; M. Blokesch

DOI : 10.1128/JB.00034-21

Growing away from monocultures – interdependent growth conditions for studying antibacterial and antiphage systems

M. Blokesch

DOI : 10.1111/1758-2229.12899

The molecular treasure box of environmental Vibrio cholerae strains

N. C. Drebes Dörr

Interbacterial competition and anti‐predatory behavior of environmental Vibrio cholerae strains

N. C. Drebes Dörr; M. Blokesch

DOI : 10.1111/1462-2920.15224

Comparison of chitin‐induced natural transformation in pandemic Vibrio cholerae O1 El Tor strains

S. Stutzmann; M. Blokesch

DOI : 10.1111/1462-2920.15214

A Vibriophage Takes Antirepression to the Next Level

L. F. Lemos Rocha; M. Blokesch

DOI : 10.1016/j.chom.2020.03.019

Selection of Vibrio crassostreae relies on a plasmid expressing a type 6 secretion system cytotoxic for host immune cells

D. Piel; M. Bruto; A. James; Y. Labreuche; C. Lambert  et al.

DOI : 10.1111/1462-2920.14776

The type IV pilus protein PilU functions as a PilT-dependent retraction ATPase

D. W. Adams; J. M. Pereira; C. Stoudmann; S. Stutzmann; M. Blokesch

DOI : 10.1371/journal.pgen.1008393

Neighbor predation linked to natural competence fosters the transfer of large genomic regions in Vibrio cholerae

N. Matthey; S. Stutzmann; C. Stoudmann; N. Guex; C. Iseli  et al.

DOI : 10.7554/eLife.48212

DNA-uptake pili of Vibrio cholerae are required for chitin colonization and capable of kin recognition via sequence-specific self-interaction

D. W. Adams; S. Stutzmann; C. Stoudmann; M. Blokesch

DOI : 10.1038/s41564-019-0479-5

Ecological implications of gene regulation by TfoX and TfoY among diverse Vibrio species

L. C. Metzger; N. Matthey; C. Stoudmann; E. J. Collas; M. Blokesch

DOI : 10.1111/1462-2920.14562

Cellular Microbiology Interview - Dr. Melanie Blokesch

M. Blokesch

DOI : 10.1111/cmi.13002

Mechanisms of DNA Uptake by Naturally Competent Bacteria

D. Dubnau; M. Blokesch

DOI : 10.1146/annurev-genet-112618-043641

Two nanomachines drive evolution in diverse Vibrio species

N. Matthey

Long-Read-Based Genome Sequences of Pandemic and Environmental Vibrio cholerae Strains

N. Matthey; N. C. Drebes Dörr; M. Blokesch

DOI : 10.1128/MRA.01574-18

Molecular insights into Vibrio cholerae’s intra-amoebal host-pathogen interactions

C. Van der Henst; A. S. Vanhove; N. C. Drebes Dörr; S. Stutzmann; C. Stoudmann  et al.

DOI : 10.1038/s41467-018-05976-x

Bacterial type VI secretion system facilitates niche domination

N. C. Drebes Dörr; M. Blokesch

DOI : 10.1073/pnas.1812776115

QstR-dependent regulation of natural competence and type VI secretion in Vibrio cholerae

M. Jaskolska; S. Stutzmann; C. Stoudmann; M. Blokesch

DOI : 10.1093/nar/gky717

Eco-Evolutionary Dynamics Linked to Horizontal Gene Transfer in Vibrios

F. Le Roux; M. Blokesch

DOI : 10.1146/annurev-micro-090817-062148

Modeling Key Drivers of Cholera Transmission Dynamics Provides New Perspectives for Parasitology

A. Rinaldo; E. Bertuzzo; M. Blokesch; L. Mari; M. Gatto

DOI : 10.1016/j.pt.2017.04.002

Interbacterial predation as a strategy for DNA acquisition in naturally competent bacteria

J.-W. Veening; M. Blokesch

DOI : 10.1038/nrmicro.2017.66

In and out—contribution of natural transformation to the shuffling of large genomic regions

M. Blokesch

DOI : 10.1016/j.mib.2017.04.001

Circulation of a Quorum-Sensing-Impaired Variant of Vibrio cholerae Strain C6706 Masks Important Phenotypes

S. Stutzmann; M. Blokesch

DOI : 10.1128/mSphere.00098-16

Independent Regulation of Type VI Secretion in Vibrio cholerae by TfoX and TfoY

L. C. Metzger; S. Stutzmann; T. Scrignari; C. Van der Henst; N. Matthey  et al.

DOI : 10.1016/j.celrep.2016.03.092

Natural competence for transformation

M. Blokesch

DOI : 10.1016/j.cub.2016.08.058

The DNA-Uptake Process of Naturally Competent Vibrio cholerae

N. Matthey; M. Blokesch

DOI : 10.1016/j.tim.2015.10.008

Regulation of competence-mediated horizontal gene transfer in the natural habitat of Vibrio cholerae

L. C. Metzger; M. Blokesch

DOI : 10.1016/j.mib.2015.10.007

An intracellular replication niche for Vibrio cholerae in the amoeba Acanthamoeba castellanii

C. Van Der Henst; T. Scrignari; C. Maclachlan; M. Blokesch

DOI : 10.1038/ismej.2015.165

Competence-induced type VI secretion might foster intestinal colonization by Vibrio cholerae

M. Blokesch

DOI : 10.1002/bies.201500101

The emergence of Vibrio pathogens in Europe: ecology, evolution, and pathogenesis (Paris, 11–12th March 2015)

F. Le Roux; K. M. Wegner; C. Baker-Austin; L. Vezzulli; C. R. Osorio  et al.

DOI : 10.3389/fmicb.2015.00830

Leben und sterben lassen – horizontaler Gentransfer in Vibrio cholerae

M. Blokesch

DOI : 10.1007/s12268-015-0572-0

The type VI secretion system of Vibrio cholerae fosters horizontal gene transfer

S. Borgeaud; L. C. Metzger; T. Scrignari; M. Blokesch

DOI : 10.1126/science.1260064

Protocols for Visualizing Horizontal Gene Transfer in Gram-Negative Bacteria Through Natural Competence

M. Blokesch

DOI : 10.1007/8623_2015_46.

Regulatory elements involved in the expression of competence genes in naturally transformable Vibrio cholerae

M. Lo Scrudato; S. Borgeaud; M. Blokesch

DOI : 10.1186/s12866-014-0327-y

Probing the size of proteins with glass nanopores

L. J. Steinbock; S. Krishnan; R. D. Bulushev; S. Borgeaud; M. Blokesch  et al.

DOI : 10.1039/C4NR05001K

Glucose- but Not Rice-Based Oral Rehydration Therapy Enhances the Production of Virulence Determinants in the Human Pathogen Vibrio cholerae

J. Kühn; F. Finger; E. Bertuzzo; S. Borgeaud; M. Gatto  et al.

DOI : 10.1371/journal.pntd.0003347

DNA Transport across the Outer and Inner Membranes of Naturally Transformable Vibrio cholerae Is Spatially but Not Temporally Coupled

P. Seitz; M. Blokesch

DOI : 10.1128/mBio.01409-14

Composition of the DNA-uptake complex of Vibrio cholerae

L. C. Metzger; M. Blokesch

DOI : 10.4161/mge.28142

ComEA Is Essential for the Transfer of External DNA into the Periplasm in Naturally Transformable Vibrio cholerae Cells

P. Seitz; H. Pezeshgi Modarres; S. Borgeaud; R. D. Bulushev; L. J. Steinbock  et al.

DOI : 10.1371/journal.pgen.1004066

Mechanistic aspects of DNA uptake in naturally competent Vibrio cholerae

P. M. Seitz

The regulatory circuit of natural competence for transformation in the human pathogen Vibrio cholerae

M. Lo Scrudato

DNA-uptake machinery of naturally competent Vibrio cholerae

P. Seitz; M. Blokesch

DOI : 10.1073/pnas.1315647110

Evidence for Two Different Regulatory Mechanisms Linking Replication and Segregation of Vibrio cholerae Chromosome II

T. Venkova-Canova; J. H. Baek; P. C. Fitzgerald; M. Blokesch; D. K. Chattoraj

DOI : 10.1371/journal.pgen.1003579

The Janthinobacterium sp. HH01 Genome Encodes a Homologue of the V. cholerae CqsA and L. pneumophila LqsA Autoinducer Synthases

C. Hornung; A. Poehlein; F. S. Haack; M. Schmidt; K. Dierking  et al.

DOI : 10.1371/journal.pone.0055045

A transcriptional regulator linking quorum sensing and chitin induction to render Vibrio cholerae naturally transformable

M. Lo Scrudato; M. Blokesch

DOI : 10.1093/nar/gkt041

Overexpression of the tcp Gene Cluster Using the T7 RNA Polymerase/Promoter System and Natural Transformation-Mediated Genetic Engineering of Vibrio cholerae

S. Borgeaud; M. Blokesch

DOI : 10.1371/journal.pone.0053952

Cues and regulatory pathways involved in natural competence and transformation in pathogenic and environmental Gram-negative bacteria

P. Seitz; M. Blokesch

DOI : 10.1111/j.1574-6976.2012.00353.x

A quorum sensing-mediated switch contributes to natural transformation of Vibrio cholerae

M. Blokesch

DOI : 10.4161/mge.22284

TransFLP - A Method to Genetically Modify Vibrio cholerae Based on Natural Transformation and FLP-recombination

M. Blokesch

DOI : 10.3791/3761

The Regulatory Network of Natural Competence and Transformation of Vibrio cholerae

M. Lo Scrudato; M. Blokesch

DOI : 10.1371/journal.pgen.1002778

Reassessment of the 2010-2011 Haiti cholera outbreak and rainfall-driven multiseason projections

A. Rinaldo; E. Bertuzzo; L. Mari; L. Righetto; M. Blokesch  et al.

DOI : 10.1073/pnas.1203333109

Chitin colonization, chitin degradation and chitin-induced natural competence of Vibrio cholerae are subject to catabolite repression

M. Blokesch

DOI : 10.1111/j.1462-2920.2011.02689.x

Prediction of the spatial evolution and effects of control measures for the unfolding Haiti cholera outbreak

E. Bertuzzo; L. Mari; L. Righetto; M. Gatto; R. Casagrandi  et al.

DOI : 10.1029/2011GL046823

A transmission model of the 2010 cholera epidemic in haiti

A. Rinaldo; M. Blokesch; E. Bertuzzo; L. Mari; L. Righetto  et al.

DOI : 10.1059/0003-4819-155-6-201109200-00018

Quorum Sensing Contributes to Natural Transformation of Vibrio cholerae in a Species-Specific Manner

G. Suckow; P. Seitz; M. Blokesch

DOI : 10.1128/JB.05396-11

Genetic manipulation of Vibrio cholerae by combining natural transformation with FLP recombination

O. De Souza Silva; M. Blokesch

DOI : 10.1016/j.plasmid.2010.08.001

Natural transformation of Vibrio cholerae as a tool - Optimizing the procedure

R. L. Marvig; M. Blokesch

DOI : 10.1186/1471-2180-10-155

The extracellular nuclease Dns and its role in natural transformation of Vibrio cholerae

M. Blokesch; G. K. Schoolnik

DOI : 10.1128/JB.00959-08

Serogroup conversion of Vibrio cholerae in aquatic reservoirs

M. Blokesch; G. K. Schoolnik

DOI : 10.1371/journal.ppat.0030081

Properties of the [NiFe]-hydrogenase maturation protein HypD

M. Blokesch; A. Böck

DOI : 10.1016/j.febslet.2006.06.045

Maturation of hydrogenases

A. Böck; P. W. King; M. Blokesch; M. C. Posewitz

The biosynthetic routes for carbon monoxide and cyanide in the Ni-Fe active site of hydrogenases are different

W. Roseboom; M. Blokesch; A. Böck; S. P. J. Albracht

DOI : 10.1016/j.febslet.2004.12.013

Chitin induces natural competence in Vibrio cholerae

K. L. Meibom; M. Blokesch; N. A. Dolganov; C.-Y. Wu; G. K. Schoolnik

DOI : 10.1126/science.1120096

HybF, a zinc-containing protein involved in NiFe hydrogenase maturation

M. Blokesch; M. Rohrmoser; S. Rode; A. Böck

DOI : 10.1128/JB.186.9.2603-2611.2004

Analysis of the transcarbamoylation-dehydration reaction catalyzed by the hydrogenase maturation proteins HypF and HypE

M. Blokesch; A. Paschos; A. Bauer; S. Reissmann; N. Drapal  et al.

DOI : 10.1111/j.1432-1033.2004.04280.x

The complex between hydrogenase-maturation proteins HypC and HypD is an intermediate in the supply of cyanide to the active site iron of [NiFe]-hydrogenases

M. Blokesch; S. P. J. Albracht; B. F. Matzanke; N. M. Drapal; A. Jacobi  et al.

DOI : 10.1016/j.jmb.2004.09.040

Network of hydrogenase maturation in Escherichia coli: role of accessory proteins HypA and HybF

M. Hube; M. Blokesch; A. Böck

DOI : 10.1128/JB.184.14.3879-3885.2002

Maturation of [NiFe]-hydrogenases in Escherichia coli: the HypC cycle

M. Blokesch; A. Böck

DOI : 10.1016/S0022-2836(02)01070-7

Metal insertion into NiFe-hydrogenases

M. Blokesch; A. Paschos; E. Theodoratou; A. Bauer; M. Hube  et al.

DOI : 10.1042/bst0300674

Interplay between the specific chaperone-like proteins HybG and HypC in maturation of hydrogenases 1, 2, and 3 from Escherichia coli

M. Blokesch; A. Magalon; A. Böck

DOI : 10.1128/JB.183.9.2817-2822.2001

Fidelity of metal insertion into hydrogenases

A. Magalon; M. Blokesch; E. Zehelein; A. Böck

DOI : 10.1016/S0014-5793(01)02525-X