Cristina Ramona Cudalbu

EPFL ENT-R CIBM-AIT
CH F0 628 (Bâtiment CH)
Station 6
CH-1015 Lausanne

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Administrative data

Fields of expertise

  •  In vivo proton, phosphorus, carbon and nitrogen MR Spectroscopy 
  • Chronic  Hepatic Encephalopathy, Hyperammonemia
  • Brain metabolites quantification and macromolecules
  • In vivo proton Spectroscopic Imaging 
  • Magnetic Resonance Imaging, Diffusion Weighted Imaging 
  •  Brain tumors 
  • Dynamic nuclear polarization 
     

Infoscience publications

Selected publications

Research

Current work

Development: implement/validate new acquisition and quantification techniques for in vivo proton, phosphorous, carbon, nitrogen MRS
-        Implement new acquisition techniques for fast spectroscopic imaging and diffusion spectroscopy
-        Implement new techniques for brain macromolecules quantification

Animal models: chronic liver failure/chronic hepatic encephalopathy, Brain tumors, creatine deficiencies, etc

 

Grants

2013-2017: Co-applicant in FP7-PEOPLE Marie Curie Initial Training Network project (Transforming Magnetic Resonance Spectroscopy into a Clinical Tool (TRANSACT))
 
 2014: PI for the Industrial grant VSL Pharmaceuticals Inc. 
 
 2014-2016: Co-applicant in the Swiss Bridge Foundation application "Towards patient-specific treatments in glioblastoma: Comparison and validation of high-resolution imaging and molecular profiles of human glioblastoma and respective paired orthotopic xenografts in the mouse" (PI Andreas Hottinger)
 
 2017-2018: Co-applicant in the Swiss Cancer League application “Characterizing invasiveness of patient derived brain tumor transplants in mice by gene expression profiling in association with metabolite profiles obtained by magnetic resonance spectroscopy (MRS). A pilot project”, (PI Monika Hegi)
 
 2017-2021: Swiss National Science Foundation; grants n° 310030_173222/1 to Cudalbu&Braissant&McLin. “Translational Non-Invasive Metabolic Studies towards Novel Treatments of Chronic Hepatic Encephalopathy in Developing Brain, from 3D Organotypic Brain Cell Cultures to the In vivo Rat and Human Brain.”
 
 2017-2021: Swiss National Science Foundation; grants n° 31003A-175778/1 to Braissant&Cudalbu. “Cerebral creatine deficiency syndromes: New in vivo AAV approaches to treat SLC6A8 deficiency.”